Cheng Cao Sun
Affiliation: Wuhan University
Sun C, Li S, Hu W, Zhang J, Zhou Q, Liu C, et al
. Comprehensive Analysis of the Expression and Prognosis for E2Fs in Human Breast Cancer. Mol Ther. 2019;: pubmed publisher
..This study implied that E2F1-3, 5, 7, and 8 are potential targets of precision therapy for patients with breast cancer and that E2F4 and 6 are new biomarkers for the prognosis of breast cancer. ..
Hu W, Bi Z, Chen Z, Liu C, Li L, Zhang F, et al
. Emerging landscape of circular RNAs in lung cancer. Cancer Lett. 2018;427:18-27 pubmed publisher
..This paper also summarizes the recent advances in circRNA biogenesis, analyzes the role of circRNAs in cancers, and discusses the potential mechanisms of circRNAs in lung cancer. ..
Zhou Q, Hu W, Zhu W, Zhang F, Lin Lin L, Liu C, et al
. Long non coding RNA XIST as a prognostic cancer marker - A meta-analysis. Clin Chim Acta. 2018;482:1-7 pubmed publisher
..33) and tumor size (OR = 3.10, 95% CI: 2.24-4.30). LncRNA XIST may serve as a potential biomarker to predict solid tumor prognosis. This molecule can be effectively used to predict the clinical and pathological features of cancers. ..
Fang J, Sun C, Gong C. Long noncoding RNA XIST acts as an oncogene in non-small cell lung cancer by epigenetically repressing KLF2 expression. Biochem Biophys Res Commun. 2016;478:811-7 pubmed publisher
..Additionally, rescue experiments revealed that XIST's oncogenic functions were partly depending on silencing KLF2 expression. Collectively, our findings expound how XIST over-expression endows an oncogenic function in NSCLC. ..
Pan J, Zhang F, Sun C, Li S, Li G, Gong F, et al
. miR-134: A Human Cancer Suppressor?. Mol Ther Nucleic Acids. 2017;6:140-149 pubmed publisher
..Herein, we review the crucial roles of miR-134 in scores of human cancers via analyzing latest investigations, which might provide evidence for cancer diagnose, treatment, prognosis, or further investigations. ..
Pan J, Sun C, Bi Z, Chen Z, Li S, Li Q, et al
. miR-206/133b Cluster: A Weapon against Lung Cancer?. Mol Ther Nucleic Acids. 2017;8:442-449 pubmed publisher
..Hence, in this review, we summarize the role and potential mechanisms of the miR-206/133b cluster in lung cancer. ..
Sun C, Zhang L, Li G, Li S, Chen Z, Fu Y, et al
. The lncRNA PDIA3P Interacts with miR-185-5p to Modulate Oral Squamous Cell Carcinoma Progression by Targeting Cyclin D2. Mol Ther Nucleic Acids. 2017;9:100-110 pubmed publisher
..Therefore, our study demonstrated that PDIA3P may be a therapeutic target for the treatment of OSCC. ..
Zhang Z, Chen J, Xia S, Zhao H, Yang J, Zhang H, et al
. Long intergenic non-protein coding RNA 319 aggravates lung adenocarcinoma carcinogenesis by modulating miR-450b-5p/EZH2. Gene. 2018;650:60-67 pubmed publisher
..This results and findings provide a novel insight for lung adenocarcinoma tumorigenesis. ..