Research Topics
Species | Dong Dong WuSummaryCountry: China Publications
| Collaborators
|
Detail Information
Publications
Evolution and function of de novo originated genesDong Dong Wu
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China Electronic address
Mol Phylogenet Evol 67:541-5. 2013..Examinations of the function of de novo origin and the function of noncoding RNA genes should become more frequent and appreciated in the future studies...
Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hairDong Dong Wu
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, PR China
BMC Evol Biol 8:241. 2008....
Positive selection on the gene RNASEL: correlation between patterns of evolution and functionWei Jin
Laboratory for Conservation and Utilization of Bio resource, Yunnan University, Kunming, China
Mol Biol Evol 29:3161-8. 2012..We provide evidence that positive selection has operated on the RNASEL gene, and its evolution is correlated with its function in pathogen defense and cancer association...
Positive selection on the osteoarthritis-risk and decreased-height associated variants at the GDF5 gene in East AsiansDong Dong Wu
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
PLoS ONE 7:e42553. 2012....
A profound role for the expansion of trypsin-like serine protease family in the evolution of hematophagy in mosquitoDong Dong Wu
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
Mol Biol Evol 26:2333-41. 2009..Our results suggest that the expansion and diversification of the Tryp_SPc domain family in mosquito was driven by positive selection and helps to explain the adaptive hematophagy of the mosquito...
De novo origin of human protein-coding genesDong Dong Wu
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
PLoS Genet 7:e1002379. 2011..Our results are inconsistent with the traditional view that the de novo origin of new genes is very rare, thus there should be greater appreciation of the importance of the de novo origination of genes...
Multi-locus analysis reveals a different pattern of genetic diversity for mitochondrial and nuclear DNA between wild and domestic pigs in East AsiaYin Qiu Ji
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
PLoS ONE 6:e26416. 2011....
Correlated evolution among six gene families in Drosophila revealed by parallel change of gene numbersDong Dong Wu
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
Genome Biol Evol 3:396-400. 2011..In conclusion, we propose that the correlated evolution among these six gene families in Drosophila is a signature of a parallel response to ecological adaptation...
Eukaryotic origin of a metabolic pathway in virus by horizontal gene transferDong Dong Wu
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, China
Genomics 98:367-9. 2011..g. thymidylate synthesis, and DNA replication) in Hz-1 virus. In conclusion, we provide an example of horizontal gene transfer of functionally related genes in a pathway to prokaryote from eukaryote...
Evidence for positive selection on the Osteogenin (BMP3) gene in human populationsDong Dong Wu
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
PLoS ONE 5:e10959. 2010..Osteogenin (BMP3) plays an important role in skeletal development and bone osteogenesis as an antagonist of the osteogenic bone morphogenetic proteins, and negatively regulates bone mineral density...
Different level of population differentiation among human genesDong Dong Wu
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, PR China
BMC Evol Biol 11:16. 2011....
Positive selection drives population differentiation in the skeletal genes in modern humansDong Dong Wu
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China
Hum Mol Genet 19:2341-6. 2010..In conclusion, we provide genetic evidence supporting the rapid evolution of the human skeletal system and the associated diversity of phenotypes...
Intriguing balancing selection on the intron 5 region of LMBR1 in human populationFang He
State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China
PLoS ONE 3:e2948. 2008..Mutation in this non-coding region is associated with preaxial polydactyly, and may play crucial roles in the evolution of limb and skeletal system...
