Kit-Fai Wong

Summary

Country: China

Publications

  1. pmc Application of tri-colour, dual fusion fluorescence in situ hybridization (FISH) system for the characterization of BCR-ABL1 fusion in chronic myelogenous leukaemia (CML) and residual disease monitoring
    Lisa Lp Siu
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, PR China
    BMC Blood Disord 9:4. 2009
  2. pmc Virtual blood bank
    Kit Fai Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, China
    J Pathol Inform 2:6. 2011
  3. pmc Penicillium marneffei Infection in AIDS
    Stephenie Y N Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong
    Patholog Res Int 2011:764293. 2011
  4. doi request reprint Double minutes and MYC amplification: a combined May-Grunwald Giemsa and fluorescence in situ hybridization study
    K F Wong
    Dept of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Rd, Kowloon, Hong Kong SAR, China
    Am J Clin Pathol 141:280-4. 2014
  5. ncbi request reprint Cytogenetic biodosimetry: what it is and how we do it
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, Jordan, Hong Kong
    Hong Kong Med J 19:168-73. 2013
  6. ncbi request reprint Virtual blood banking in Hong Kong
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, Jordan, Hong Kong
    Hong Kong Med J 18:304-9. 2012
  7. pmc Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms
    Chor Sang Chim
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong
    J Transl Med 9:197. 2011
  8. ncbi request reprint Multicentric osteosarcoma presenting as retrobulbar mass: a diagnostic enigma
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong
    Pediatr Blood Cancer 46:815-9. 2006
  9. ncbi request reprint Inv(1)(p22q25) in chronic myeloproliferative disease: constitutional or clonal defect?
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Hong Kong SAR, China
    Cancer Genet Cytogenet 158:188-91. 2005
  10. ncbi request reprint Polyclonal B-cell lymphocytosis mimicking malignant lymphoma in a newborn
    Kit Fai Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, China
    Arch Pathol Lab Med 129:251-2. 2005

Collaborators

Detail Information

Publications40

  1. pmc Application of tri-colour, dual fusion fluorescence in situ hybridization (FISH) system for the characterization of BCR-ABL1 fusion in chronic myelogenous leukaemia (CML) and residual disease monitoring
    Lisa Lp Siu
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, PR China
    BMC Blood Disord 9:4. 2009
    ....
  2. pmc Virtual blood bank
    Kit Fai Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, China
    J Pathol Inform 2:6. 2011
    ..Thus, the virtual blood bank can help ensure that the right patient receives the right amount of the right blood component at the right time...
  3. pmc Penicillium marneffei Infection in AIDS
    Stephenie Y N Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong
    Patholog Res Int 2011:764293. 2011
    ..Secondary prophylaxis may be discontinued with a low risk of relapse of the infection once the immune dysfunction has improved...
  4. doi request reprint Double minutes and MYC amplification: a combined May-Grunwald Giemsa and fluorescence in situ hybridization study
    K F Wong
    Dept of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Rd, Kowloon, Hong Kong SAR, China
    Am J Clin Pathol 141:280-4. 2014
    ....
  5. ncbi request reprint Cytogenetic biodosimetry: what it is and how we do it
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, Jordan, Hong Kong
    Hong Kong Med J 19:168-73. 2013
    ..This was part of the contingency plan for emergency measures against radiation accidents at nuclear power stations...
  6. ncbi request reprint Virtual blood banking in Hong Kong
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, Jordan, Hong Kong
    Hong Kong Med J 18:304-9. 2012
    ..The system can be implemented either locally in the same hospital with a central blood bank, or in a more remote and networked site without a nearby supporting blood bank...
  7. pmc Methylation of miR-34a, miR-34b/c, miR-124-1 and miR-203 in Ph-negative myeloproliferative neoplasms
    Chor Sang Chim
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong
    J Transl Med 9:197. 2011
    ..MicroRNA (miR) miR-34a, -34b/c, -124-1 and -203 are tumor suppressor miRs implicated in carcinogenesis...
  8. ncbi request reprint Multicentric osteosarcoma presenting as retrobulbar mass: a diagnostic enigma
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong
    Pediatr Blood Cancer 46:815-9. 2006
    ..A hypertetraploid clone with complex structural abnormalities was demonstrated by cytogenetic study...
  9. ncbi request reprint Inv(1)(p22q25) in chronic myeloproliferative disease: constitutional or clonal defect?
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Hong Kong SAR, China
    Cancer Genet Cytogenet 158:188-91. 2005
    ..The inv(1) is an acquired clonal abnormality in one patient and a constitutional defect in the other. To our knowledge, this is the first report on the occurrence of inv(1)(p22q25) in hematolymphoid malignancies...
  10. ncbi request reprint Polyclonal B-cell lymphocytosis mimicking malignant lymphoma in a newborn
    Kit Fai Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, China
    Arch Pathol Lab Med 129:251-2. 2005
    ..Cytogenetic analysis showed a normal karyotype, and viral cultures and serologic studies yielded negative results. The polyclonal lymphocytosis was self-limiting and disappeared within a month...
  11. ncbi request reprint Diffuse large B-cell lymphoma with occult marrow involvement and a novel t(9;10)(q32;q22)
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong SAR, China
    Cancer Genet Cytogenet 147:68-70. 2003
    ....
  12. ncbi request reprint Isochromosome 7q in Down syndrome
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong SAR, China
    Cancer Genet Cytogenet 164:152-4. 2006
    ..It has rarely been described in myelodysplastic syndrome and acute myeloid leukemia. We report the occurrence of i(7q) as the primary abnormality in a 2-year-old boy with Down syndrome and minimally differentiated acute myeloid leukemia...
  13. ncbi request reprint Metastatic melanoma
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, China
    Br J Haematol 134:554. 2006
  14. ncbi request reprint Transformed follicular lymphoma with concurrent t(2;3), t(8;14) and t(14;18)
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong SAR, China
    Cancer Genet Cytogenet 173:68-70. 2007
    ..3),t(2;3)(p12;q27),t(8;14)(q24.1;q32),+12,t(14;18)(q32;q21),+21. To my knowledge, this is the first reported case of simultaneous occurrence of t(2;3), t(8;14), and t(14;18) in transformed follicular lymphoma...
  15. ncbi request reprint Diagnosis of familial amyloidotic polyneuropathy by bone marrow biopsy
    Kit Fai Wong
    Department of Pathology, Queen Elizabeth Hospital, Queen Mary Hospital, Hong Kong SAR, China
    Br J Haematol 139:517. 2007
  16. doi request reprint t(8;16)(p11;p13) predisposes to a transient but potentially recurring neonatal leukemia
    Kit Fai Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, China
    Hum Pathol 39:1702-7. 2008
    ..The genetic lesion only became undetectable at the molecular level at the age of 20 months. The possible role of MYST3 and CREBBP gene fusion in the pathogenesis of the leukemia is discussed...
  17. doi request reprint JAK2 V617F mutation is associated with 5q- syndrome in Chinese
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, China
    Leuk Lymphoma 50:1333-5. 2009
    ..We performed a retrospective analysis of JAK2 V617F mutation in Chinese patients with myeloid neoplasms and isolated del(5q), and were able to demonstrate the frequent occurrence of JAK2 V617F mutation in 5q- syndrome...
  18. doi request reprint Essential thrombocythemia with deleted 5q--a genetic and morphologic hybrid?
    Kit Fai Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, China
    Cancer Genet Cytogenet 201:39-41. 2010
    ....
  19. ncbi request reprint Severe acute respiratory syndrome (SARS)
    K F Wong
    Departments of Pathology and Radiology and Imaging, Queen Elizabeth Hospital, Hong Kong, China E mail
    Br J Haematol 122:171. 2003
  20. ncbi request reprint Cytomegalovirus infection associated with clonal proliferation of T-cell large granular lymphocytes: causal or casual?
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong SAR, China
    Cancer Genet Cytogenet 142:77-9. 2003
    ..The leukemic LGL are shown to be clonal by both TCR gene rearrangement and chromosomal studies. They persist after subsidence of the cytomegalovirus infection...
  21. ncbi request reprint Waldenström macroglobulinemia with a novel der(8;17)(q10;q10)
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, Kowloon, SAR, Hong Kong, China
    Cancer Genet Cytogenet 141:83-5. 2003
    ..Although this cytogenetic abnormality has been reported in a number of solid tumors, a literature review suggests also a possible association with B-cell chronic lymphoproliferative disorders...
  22. ncbi request reprint Follicular lymphoma with trisomy 18 and over-expression of BCL2 in the absence of t(14;18)(q32;q21)
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong, China
    Cancer Genet Cytogenet 123:52-4. 2000
    ..However, trephine biopsy revealed involvement of the marrow by follicular lymphoma, and cytogenetic study showed an abnormal clone with 47,XX,+18...
  23. ncbi request reprint Waldenström macroglobulinemia with karyotypic aberrations involving both homologous 6q
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, China
    Cancer Genet Cytogenet 124:137-9. 2001
    ..A literature review suggests that deletions of chromosome 6 at 6q21 are associated with lymphoplasmacytoid differentiation and IgM production in B-cell chronic lymphoproliferative disorders...
  24. ncbi request reprint Acute myeloid leukemia with concomitant trisomies 4 and 10: a distinctive form of myeloid leukemia?
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong SAR, China
    Cancer Genet Cytogenet 127:74-6. 2001
    ..These findings raise the possibility that AML with concommitant trisomy 4 and trisomy 10 may constitute a distinctive subtype of AML...
  25. ncbi request reprint Sinonasal angiosarcoma with marrow involvement at presentation mimicking malignant lymphoma: cytogenetic analysis using multiple techniques
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, SAR, Hong Kong, China
    Cancer Genet Cytogenet 129:64-8. 2001
    ..The identification of these karyotypic changes has been facilitated by the application of comparative genomic hybridization and spectral karyotyping...
  26. ncbi request reprint Chromosomal abnormalities in T-cell large granular lymphocyte leukaemia: report of two cases and review of the literature
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong SAR, China
    Br J Haematol 116:598-600. 2002
    ..This is the first report describing the possible involvement of T-cell receptor genes in karyotypic aberrations in T-LGL...
  27. ncbi request reprint Chronic lymphocytic leukemia with a novel der(8;15)(q10;q10) translocation
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, SAR, Hong Kong, China
    Cancer Genet Cytogenet 132:159-60. 2002
    ..The der(8;15) is a novel chromosomal abnormality in human malignancies. The resulting loss of 8p and trisomy 15q are both unusual chromosomal changes in chronic lymphocytic leukemia...
  28. ncbi request reprint Cytogenetic abnormalities in natural killer cell lymphoma/leukaemia--is there a consistent pattern?
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong, China
    Leuk Lymphoma 34:241-50. 1999
    ..Search for the involved genes located in this chromosome region can potentially shed light on the molecular pathogenesis of the natural killer cell neoplasms...
  29. ncbi request reprint Gain of chromosome 3/3q in B-cell chronic lymphoproliferative disorder is associated with plasmacytoid differentiation with or without IgM overproduction
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, SAR, Hong Kong, China
    Cancer Genet Cytogenet 136:82-5. 2002
    ..The relationship between the gain of chromosome 3 and plasmacytoid differentiation in B-cell chronic lymphoproliferative disorders is discussed...
  30. ncbi request reprint Precursor T-lymphoblastic leukemia with a novel t(1;22)(p34;q13)
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, Hong Kong SAR, China
    Cancer Genet Cytogenet 136:146-8. 2002
    ..The t(1;22)(p34;q13) is a novel chromosomal abnormality in human malignancies and is probably a variant form of the t(1;14)(p34;q11) found in precursor T-ALL...
  31. ncbi request reprint A novel t(2;3)(q31;p13) in acute myelocytic leukemia
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, SAR, Hong Kong, China
    Cancer Genet Cytogenet 138:77-9. 2002
    ..Nevertheless, interphase cytogenetics by fluorescence in situ hybridization using a chromosome 8 alpha-satellite DNA probe showed that the percentage of cells with three hybridization signals was within the control range...
  32. ncbi request reprint Hypoplastic myelodysplastic syndrome-a clinical, morphologic, or genetic diagnosis?
    K F Wong
    Department of Pathology, Queen Elizabeth Hospital, 30 Gascoigne Road, Kowloon, SAR, Hong Kong, China
    Cancer Genet Cytogenet 138:85-8. 2002
    ..The case illustrates the problems in the differentiation between aplastic anemia and hypoplastic MDS...
  33. ncbi request reprint Natural killer cell neoplasms: a distinctive group of highly aggressive lymphomas/leukemias
    Michael M C Cheung
    Department of Clinical Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong
    Semin Hematol 40:221-32. 2003
    ..Aggressive NK cell leukemia must be distinguished from T-cell large granular lymphocyte leukemia and indolent NK cell lymphoproliferative disorder, both of which are indolent...
  34. ncbi request reprint Nucleolated variant of mantle cell lymphoma with leukemic manifestations mimicking prolymphocytic leukemia
    Kit Fai Wong
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong, People s Republic of China
    Am J Clin Pathol 117:246-51. 2002
    ..This study documents the existence of an unusual leukemic form of mantle cell lymphoma with prominent nucleoli; the clinicopathologic features that distinguish it from other chronic lymphoproliferative disorders are discussed...
  35. pmc Specific patterns of gene methylation in natural killer cell lymphomas : p73 is consistently involved
    Lisa Lai Ping Siu
    Department of Medicine, Queen Mary Hospital, Hong Kong, People s Republic of China
    Am J Pathol 160:59-66. 2002
    ..These results suggest that p73 may be an important target in the neoplastic transformation of NK cells, and the demonstration of its methylation may serve as a potential molecular tool for NK cell lymphoma detection...
  36. ncbi request reprint Valproate-associated dysmyelopoiesis in elderly patients
    Chi Chiu So
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong, People s Republic of China
    Am J Clin Pathol 118:225-8. 2002
    ..A correct diagnosis is important for acute patient anagement and for prognostication...
  37. ncbi request reprint Hb Kodaira II: a high oxygen affinity variant with a novel mutation in the beta-globin gene and phenotypic identity to Hb Kodaira
    Chi Chiu So
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong, SAR, China
    Hemoglobin 26:205-7. 2002
  38. ncbi request reprint Transfusion medicine illustrated. A surfeit of spherocytes
    Chi Chiu So
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong, China SAR
    Transfusion 43:131. 2003
  39. ncbi request reprint May-Hegglin anomaly
    Chi Chiu So
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong, China SAR
    Br J Haematol 120:373. 2003
  40. ncbi request reprint Bone marrow penicilliosis
    Chi Chui So
    Department of Pathology, Queen Elizabeth Hospital, Hong Kong, China, SAR
    Br J Haematol 117:777. 2002