Bohai Wen

Summary

Country: China

Publications

  1. pmc Potential serodiagnostic markers for Q fever identified in Coxiella burnetii by immunoproteomic and protein microarray approaches
    Xiaolu Xiong
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Dong dia jie, Beijing 100071, China
    BMC Microbiol 12:35. 2012
  2. pmc Simultaneous detection of Anaplasma marginale and a new Ehrlichia species closely related to Ehrlichia chaffeensis by sequence analyses of 16S ribosomal DNA in Boophilus microplus ticks from Tibet
    Bohai Wen
    Department of Microbiology, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China
    J Clin Microbiol 40:3286-90. 2002
  3. ncbi Ehrlichiae and ehrlichial diseases in china
    Bohai Wen
    Department of Microbiology, Beijing Institute of Microbiology and Epidemiology, PR China
    Ann N Y Acad Sci 990:45-53. 2003
  4. ncbi Analysis of immunoprotectivity of the recombinant OmpA of Rickettsia heilongjiangensis
    Yanmei Jiao
    Beijing Institute of Microbiology and Epidemiology and State Key Laboratory of Pathogen and Biosecurity, Fengtai, Beijing 100071, China
    Ann N Y Acad Sci 1063:261-5. 2005
  5. ncbi Balb/c mouse model and real-time quantitative polymerase chain reaction for evaluation of the immunoprotectivity against Q fever
    Jingbo Zhang
    Beijing Institute of Microbiology and Epidemiology, Fengtai, Beijing 100071, China
    Ann N Y Acad Sci 1063:171-5. 2005
  6. pmc Complete genome sequence of Rickettsia heilongjiangensis, an emerging tick-transmitted human pathogen
    Changsong Duan
    State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, 20 Dong Da Jie St, Fengtai, Beijing 100071, China
    J Bacteriol 193:5564-5. 2011
  7. pmc Efficient activation of T cells by human monocyte-derived dendritic cells (HMDCs) pulsed with Coxiella burnetii outer membrane protein Com1 but not by HspB-pulsed HMDCs
    Ying Wang
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China
    BMC Immunol 12:52. 2011
  8. pmc Exploratory study on pathogenesis of far-eastern spotted fever
    Changsong Duan
    State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China
    Am J Trop Med Hyg 85:504-9. 2011
  9. ncbi Protective immunity against Q fever induced with a recombinant P1 antigen fused with HspB of Coxiella burnetii
    Qingfeng Li
    Beijing Institute of Microbiology and Epidemiology, Fengtai, Beijing 100071, China
    Ann N Y Acad Sci 1063:130-42. 2005
  10. pmc Coxiella burnetii antigen-stimulated dendritic cells mediated protection against Coxiella burnetii in BALB/c mice
    Yan Wei
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China
    J Infect Dis 203:283-91. 2011

Collaborators

Detail Information

Publications12

  1. pmc Potential serodiagnostic markers for Q fever identified in Coxiella burnetii by immunoproteomic and protein microarray approaches
    Xiaolu Xiong
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Dong dia jie, Beijing 100071, China
    BMC Microbiol 12:35. 2012
    ..Coxiella burnetii is the etiological agent of Q fever. The clinical diagnosis of Q fever is mainly based on several serological tests. These tests all need Coxiella organisms which are difficult and hazardous to culture and purify...
  2. pmc Simultaneous detection of Anaplasma marginale and a new Ehrlichia species closely related to Ehrlichia chaffeensis by sequence analyses of 16S ribosomal DNA in Boophilus microplus ticks from Tibet
    Bohai Wen
    Department of Microbiology, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China
    J Clin Microbiol 40:3286-90. 2002
    ..microplus ticks is a new species of the genus Ehrlichia and is most closely related to E. chaffeensis...
  3. ncbi Ehrlichiae and ehrlichial diseases in china
    Bohai Wen
    Department of Microbiology, Beijing Institute of Microbiology and Epidemiology, PR China
    Ann N Y Acad Sci 990:45-53. 2003
    ..These results reveal that a variety of tick-borne ehrlichial agents and diseases exist in China, and the ehrlichial agents and their tick-vectors are same as or different from that in other countries at species or strain levels...
  4. ncbi Analysis of immunoprotectivity of the recombinant OmpA of Rickettsia heilongjiangensis
    Yanmei Jiao
    Beijing Institute of Microbiology and Epidemiology and State Key Laboratory of Pathogen and Biosecurity, Fengtai, Beijing 100071, China
    Ann N Y Acad Sci 1063:261-5. 2005
    ..These results suggest that the truncated OmpA of R. heilongjiangii is immunogenic for effectively inducing humoral and cell-mediated immune responses against homologous and heterologous species in the spotted fever group...
  5. ncbi Balb/c mouse model and real-time quantitative polymerase chain reaction for evaluation of the immunoprotectivity against Q fever
    Jingbo Zhang
    Beijing Institute of Microbiology and Epidemiology, Fengtai, Beijing 100071, China
    Ann N Y Acad Sci 1063:171-5. 2005
    ..The results suggest that the combination of Balb/c model and the real-time quantitative PCR assay is a reliable and sensitive way to evaluate the efficiency of vaccines against Q fever...
  6. pmc Complete genome sequence of Rickettsia heilongjiangensis, an emerging tick-transmitted human pathogen
    Changsong Duan
    State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, 20 Dong Da Jie St, Fengtai, Beijing 100071, China
    J Bacteriol 193:5564-5. 2011
    ..Rickettsia heilongjiangensis is an emerging tick-transmitted human pathogen causing far-Eastern spotted fever. Here we report the complete sequence and the main features of the genome of R. heilongjiangensis (strain 054)...
  7. pmc Efficient activation of T cells by human monocyte-derived dendritic cells (HMDCs) pulsed with Coxiella burnetii outer membrane protein Com1 but not by HspB-pulsed HMDCs
    Ying Wang
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing 100071, China
    BMC Immunol 12:52. 2011
    ..It is not clear whether Com1 and HspB have the ability to mount immune responses against C. burnetii infection...
  8. pmc Exploratory study on pathogenesis of far-eastern spotted fever
    Changsong Duan
    State Key Laboratory of Pathogens and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China
    Am J Trop Med Hyg 85:504-9. 2011
    ..i. Our results reveal that R. heilongjiangensis may cause an infection in BALB/c mice and the pathological lesions in the infected mice are associated with host inflammatory response induced by R. heilongjiangensis...
  9. ncbi Protective immunity against Q fever induced with a recombinant P1 antigen fused with HspB of Coxiella burnetii
    Qingfeng Li
    Beijing Institute of Microbiology and Epidemiology, Fengtai, Beijing 100071, China
    Ann N Y Acad Sci 1063:130-42. 2005
    ..The data from this study indicate that fusion antigen P1-HspB is a good immunogen for eliciting immunoresponses against C. burnetii, and it may be a more suitable candidate for preparing subunit vaccine against Q fever...
  10. pmc Coxiella burnetii antigen-stimulated dendritic cells mediated protection against Coxiella burnetii in BALB/c mice
    Yan Wei
    State Key Laboratory of Pathogen and Biosecurity, Beijing Institute of Microbiology and Epidemiology, Beijing, China
    J Infect Dis 203:283-91. 2011
    ..Our results suggest that PIIAg is far superior to PIAg in activating BMDCs to confer protection against C. burnetii in vivo, whereas Com1 and SecB are protective antigens because Com1- or SecB-pulsed BMDCs confer partial protection...
  11. ncbi A spiroplasma associated with tremor disease in the Chinese mitten crab (Eriocheir sinensis)
    Wen Wang
    Key Laboratory for Bioresources Technology of Jiangsu Province, College of Biological Sciences, Nanjing Normal University, Nanjing 210097, PR China
    Microbiology 150:3035-40. 2004
    ..This is believed to be the first time a spiroplasma has been found in a crustacean. These findings are not only significant for studies on pathogenic spiroplasmas, but also have implications for studies of freshwater ecology...
  12. ncbi Purification and antigenic characteristics of a rickettsia-like organism from the oyster Crassostrea ariakensis
    Xinzhong Wu
    College of Animal Sciences, Zhejiang University, 268 Kaixuan Road, Hangzhou 310029, China
    Dis Aquat Organ 67:149-54. 2005
    ..The present results advance our knowledge of RLO protein antigens, and several proteins have been identified that could potentially be useful for diagnostic assays or for production of experimental immunostimulants...