Research Topics
Species | Meng WeiSummaryCountry: China Publications
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Detail Information
Publications
Five-year clinical follow-up of unprotected left main bifurcation lesion stenting: one-stent versus two-stent techniques versus double-kissing crush techniqueShao Liang Chen
Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, 210006 China
EuroIntervention 8:803-14. 2012....
Comparison of paclitaxal vs. sirolimus eluting stents with bio-degradable polymer for the treatment of coronary bifurcation lesions: subgroup analysis from DKCRUSH-I and DKCRUSH-II studiesShao Liang Chen
Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China
Chin Med J (Engl) 125:3382-7. 2012..The present study aimed to investigate the one-year clinical outcome after DK crush stenting using PES (Taxus(TM)) vs. SES-BDP (Excel(TM)) from our database...
Coronary bifurcation angle from 3-D predicts clinical outcomes after stenting bifurcation lesionsShao Liang Chen
Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China
Chin Med J (Engl) 125:2083-8. 2012..The present study was to investigate the dynamic change of BA and clinical relevance for patients with coronary bifurcation lesions treated by drug-eluting stent (DES)...
Intravenous injection of nicardipine changed the distribution of coronary artery endothelial shear stress and fluid dynamics in patients with unstable anginaShao Liang Chen
Department of Cardiology, Nanjing Medical University, Nanjing, Jiangsu, China
Chin Med J (Engl) 125:3240-5. 2012..Coronary endothelial shear stress (ESS) triggered the development of atherosclerosis. However, the effect of calcium channel antagonist on the distribution of ESS remained unclear...
Angioscopy study from a large patient population comparing sirolimus-eluting stent with biodegradable versus durable polymerShao Liang Chen
Division of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China
Catheter Cardiovasc Interv 80:420-8. 2012..This study aimed to compare the neointimal coverage (NIC), subclinical thrombus, color of plaque underneath the stent at 9-month after implantation of sirolimus-eluting stent (SES) either with durable or with biodegradable polymer (BDPM)...
Hemodynamic change in wall shear stress in patients with coronary bifurcation lesions treated by double kissing crush or single-stent techniqueShao Liang Chen
Division of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China
Chin Med J (Engl) 125:1720-6. 2012..The present study aimed at investigating the hemodynamic change of wall shear stress (WSS) in patients with coronary bifurcation lesions treated by double kissing (DK) crush or one-stent with final kissing balloon inflation (FKBI)...
Acute effects of nicardipine and esmolol on the cardiac cycle, intracardiac hemodynamic and endothelial shear stress in patients with unstable angina pectoris and moderate coronary stenosis: results from single center, randomized studyShao Liang Chen
Division of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 21006, China
Cardiovasc Ther 30:162-71. 2012..This study aimed to compare the acute effects of nicardipine and esmolol on hemodynamic and endothelial shear stress (ESS) in patients with unstable angina (UA) and moderate coronary stenosis (MCS)...
Clinical outcomes after recanalization of a chronic total occluded vessel with bifurcation lesions: results from single-center, prospective, chronic total occlusion registry studyShao Liang Chen
Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing 210006, China
Chin Med J (Engl) 125:1035-40. 2012..Stenting strategies and clinical outcomes of bifurcation lesions in a chronic total occlusion (CTO) vessel after successful recanalization remain to be unknown...
Comparison of a five-year clinical outcome between Chinese women and men with de novo coronary disease treated with implantation of a drug-eluting stent: a three-center, prospective, registry studyShao Liang Chen
Division of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China
Chin Med J (Engl) 125:7-11. 2012..The present study aimed to compare the 5-year clinical outcome after DES implantation in Chinese women and men...
Novel side branch ostial stent (BIGUARD): first-in-man studyShao Liang Chen
Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China
Chin Med J (Engl) 122:2092-6. 2009..No study has reported the clinical outcome of a dedicated bifurcation stent in China. We aimed to analyze the safety and clinical outcome of a novel side branch ostial stent (BIGUARD) stent in treating coronary bifurcation lesions...
Different edge effects of paclitaxel- and sirolimus-eluting stents on proximal and distal edges in patients with unstable angina: serial intravascular ultrasound analysisShao Liang Chen
Nanjing First Hospital of Nanjing Medical University, Jiangsu, China
Chin Med J (Engl) 122:1603-9. 2009..This study aimed to compare the different vascular edge responses in patients with unstable angina and single de novo coronary lesion treated with SES and PES...
Novel side branch ostial stentShao Liang Chen
Nanjing First Hospital, Nanjing Medical University, China
J Interv Cardiol 22:145-9. 2009....
Endovascular stent-grafts treatment in acute aortic dissection (type B): clinical outcomes during early, late, or chronic phasesShaoliang Chen
Department of Cardiology, Nanjing First Hospital of Nanjing Medical University, Nanjing, China
Catheter Cardiovasc Interv 68:319-25. 2006..This is a prospective study to evaluate the clinical outcomes of endovascular repair in patients with different phases of type B aortic dissection...
Clinical outcomes of percutaneous coronary intervention for chronic total occlusion lesions in remote hospitals without on-site surgical supportShao Liang Chen
Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China
Chin Med J (Engl) 122:2278-85. 2009..This study aimed to evaluate three-year outcomes after CTO for PCI in ten centers around China where no on-site coronary artery bypass grafting (CABG) support was available...
Crush stenting with drug-eluting stents: relevance of coronary bifurcation lesion location on angiographic and clinical outcomesShao Liang Chen
Nanjing First Hospital, Nanjing Medical University, China
Clin Cardiol 33:E32-9. 2010..Data on the relevance of the location of coronary bifurcation lesions treated by crush stenting with outcomes were limited...
Clinical outcome after management of unprotected left main in-stent restenosis after bare metal or drug-eluting stentsShao Liang Chen
Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China
Chin Med J (Engl) 123:794-9. 2010..There are still a lack of data regarding the subsequent results of UPLMS in-stent restenosis (ISR). The present study aimed at determining the clinical outcome of UPLMS ISR patients after implantation of either BMS or DES...
Prediction of clinical outcomes in patients with unprotected left main trifurcation lesions treated by drug-eluting stents: importance of 2-stent technique and SYNTAX scoreShao Liang Chen
Cardiological Department, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China
J Interv Cardiol 23:352-7. 2010..There were insufficient data on the prognosis of stenting for patients with trifurcated unprotected left main lesions (UPLMS)...
Serial intravascular ultrasound analysis comparing double kissing and classical crush stenting for coronary bifurcation lesionsShao Liang Chen
Division of Cardiology, Nanjing First Hospital, Nanjing Medical University, 210006 Nanjing, China
Catheter Cardiovasc Interv 78:729-36. 2011..Compared with the classical crush, double kissing (DK) crush improved outcomes in patients with coronary bifurcation lesions. However, there is no serial intravascular ultrasound (IVUS) comparisons between these two techniques...
Twenty-four-month update on double-kissing crush stenting of bifurcation lesionsShao Liang Chen
Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China
J Interv Cardiol 22:121-7. 2009..The results confirmed a sustained, lower MACE rate at 24 months with the double kissing (DK) crush stenting technique compared with that for the classical crush stenting technique (18.1% vs. 29.9%, p = 0.044)...
Perspective on bifurcation PCIShao Liang Chen
Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu, China
J Interv Cardiol 22:99-109. 2009..This review presents a historical perspective of interventions in bifurcated lesions, with the strengths and weaknesses of the major strategies and of the new dedicated stents...
Effect of coronary bifurcation angle on clinical outcomes in Chinese patients treated with crush stenting: a subgroup analysis from DKCRUSH-1 bifurcation studyShao Liang Chen
Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China
Chin Med J (Engl) 122:396-402. 2009..We sought to compare high (> or = 60 degrees ) with low (< 60 degrees ) bifurcation angle in patients who underwent either classical or double kissing (DK) crush stenting for bifurcation lesions from the DKCRUSH-1 data base...
Clinical outcomes of contrast-induced nephropathy in patients undergoing percutaneous coronary intervention: a prospective, multicenter, randomized study to analyze the effect of hydration and acetylcysteineShao Liang Chen
Nanjing First Hospital of Nanjing Medical University, Department of Cardiology, 68 Changle Road, 210006, Nanjing, China
Int J Cardiol 126:407-13. 2008..The potential role of hydration in prevention of contrast-induced nephropathy (CIN) still remains to be unclear...
Left ventricular endocardial pacing predicts the reduction of left ventricular outflow tract pressure gradient immediately after percutaneous transseptal myocardial ablation in patients with hypertrophic obstructive cardiomyopathy refractory to medicationShao Liang Chen
Department of Cardiology, Nanjing First Hospital of Nanjing Medical University, Nanjing 210006, China
Chin Med J (Engl) 120:562-8. 2007..Hypertrophic obstructive cardiomyopathy (HOCM) carries an increased risk for sudden cardiac death. No data regarding the percutaneous transseptal myocardial ablation (PTSMA) and epicardial left ventricular pacing (LVP) were reported...
Midterm outcomes of percutaneous transluminal septal myocardial ablation in patients with hypertrophic obstructive cardiomyopathy refractory to medicationShao-Liang Chen
Cardiological Division, Nanjing First Hospital of Nanjing Medical University, Nanjing 210006, China
Chin Med J (Engl) 119:1121-4. 2006
Cardiac electromechanical mapping in analyzing the mechanism of left ventricular remodeling immediately after percutaneous transluminal septal ablation in patients with hypertrophic obstructive cardiomyopathyShao Liang Chen
Cardiological Division, Nanjing First Hospital of Nanjing Medical University, Nanjing 210006, China
Chin Med J (Engl) 118:1779-85. 2005....
Crush stenting in treating coronary bifurcate lesions: paclitaxel eluting stents versus sirolimus eluting stentsShao Liang Chen
Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, Jiangsu 210006, China
Chin Med J (Engl) 121:528-33. 2008..Because no data regarding the comparison of crush stenting with paclitaxel (PES) or sirolimus eluting stents (SES) for coronary bifurcate lesions have been reported, we compared the clinical outcomes of these two types of stents...
[DK crush technique: modified treatment of bifurcation lesions in coronary artery.]Shao-Liang Chen
Cardiological Division, Nanjing First Hospital of Nanjing Medical University, Nanjing 210006, China
Chin Med J (Engl) 118:1746-50. 2005
Crush stenting with paclitaxel-eluting or sirolimus-eluting stents for the treatment of coronary bifurcation lesionsShaoliang Chen
Department of Cardiology, Nanjing First Hospital, Nanjing Medical University, Nanjing, China
Angiology 59:475-83. 2008..In this study with crush stenting, use of sirolimus-eluting stent, compared with paclitaxel-eluting stent, yielded significantly lower late lumen loss, restenosis, and revascularization rates, with comparable safety by 8-month follow-up...
Study comparing the double kissing (DK) crush with classical crush for the treatment of coronary bifurcation lesions: the DKCRUSH-1 Bifurcation Study with drug-eluting stentsS L Chen
Cardiological Department, Nanjing First Hospital of Nanjing Medical University, Nanjing, China
Eur J Clin Invest 38:361-71. 2008..The double kissing (DK) crush technique has the potential to increase the FKBI rate, and no prospective studies on the comparison of classical with DK crush techniques have been reported...
Improvement of cardiac function after transplantation of autologous bone marrow mesenchymal stem cells in patients with acute myocardial infarctionShao Liang Chen
Department of Cardiology, Nanjing First Municipal Hospital, Nanjing Medical University, Nanjing 210006, China
Chin Med J (Engl) 117:1443-8. 2004..There is a growing interest in repairing scar area by transplanting bone marrow stem cells. However, effectiveness of intracoronary injection of bone marrow mesenchymal stem cells (BMSCs) in patients with AMI still remains unclear...
[Comparison of DK crush with classical crush technique with drug-eluting stents for the treatment of coronary bifurcation lesions from DKCRUSH-1 study]Shao Liang Chen
Department of Cardiology, Nanjing First Hospital, Nanjing Medical College, Nanjing 210006, China
Zhonghua Xin Xue Guan Bing Za Zhi 36:100-7. 2008..To determine independent factors correlated with clinical effects of DK crush and classical crush technique with drug-eluting stents on bifurcation lesions...
Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarctionShao Liang Chen
Division of Cardiology, Nanjing First Hospital, Nanjing University, Nanjing, Jiangsu Province, China
Am J Cardiol 94:92-5. 2004..Several imagining techniques demonstrated that bone marrow mesenchymal stem cells significantly improved left ventricular function...
Distal left main coronary bifurcation lesions predict worse outcome in patients undergoing percutaneous implantation of drug-eluting stents: results from the Drug-Eluting Stent for the Treatment of Left Main Disease (DISTAL) StudyShao Liang Chen
Cardiological Department, Nanjing First Hospital, Nanjing Medical University, Nanjing, PR China
Cardiology 113:264-73. 2009..We investigated the clinical outcome of stenting of unprotected left main coronary artery (LMCA)...
Tranilast stabilizes the accumulation and degranulation of resident mast cells while reducing cardiomyocyte apoptosis in a swine model of coronary microembolisationQing Yong Zhang
Division of Cardiology, Number 6 People s Hospital, Jiaotong University, Shanghai 200233, China
Clin Exp Pharmacol Physiol 37:641-6. 2010..4. These findings suggest that tranilast suppresses the accumulation and degranulation of MC while reducing cardiomyocyte apoptosis after CME...
Final kissing balloon inflation by classic crush stenting did not improve the clinical outcomes for the treatment of unprotected left main bifurcation lesions: the importance of double-kissing crush techniqueShaoliang Chen
Nanjing First Hospital, Nanjing Medical University, Jiang Su, China
Catheter Cardiovasc Interv 71:166-72. 2008..The authors compared the clinical outcomes in patients with unprotected distal left main bifurcation lesions treated by classic crush or DK crush stenting techniques...
Protective effects of salvianolate on microvascular flow in a porcine model of myocardial ischaemia and reperfusionBeibei Han
Division of Cardiology, Shanghai Sixth People s Hospital, Shanghai Jiao Tong University School of Medicine, China
Arch Cardiovasc Dis 104:313-24. 2011..Microvascular reflow is crucial for myocyte survival during ischaemia/reperfusion injury...
Proximal coronary hemodynamic changes evaluated by intracardiac echocardiography during myocardial ischemia and reperfusion in a canine modelBeibei Han
Department of Cardiology, Shanghai 6th People s Hospital, Shanghai Jiaotong University, Shanghai, PR China
Echocardiography 25:312-20. 2008....
Meta-analysis of long-term outcomes of drug-eluting stent implantations for chronic total coronary occlusionsJian Ma
Division of Cardiology, Shanghai Sixth People s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Heart Lung 40:e32-40. 2011..We reviewed outcomes of DES vs. BMS implantation for CTO lesions, to evaluate the risk-benefit ratio of DES implantation...
Combined transplantation of endothelial progenitor cells and mesenchymal stem cells into a rat model of isoproterenol-induced myocardial injuryXin Zhang
Division of Cardiology, Shanghai Sixth Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China
Arch Cardiovasc Dis 101:333-42. 2008..Endothelial progenitor cells (EPCs) and mesenchymal stem cells (MSCs) have different biological properties, but their potential for synergy in the treatment of injured myocardium has not been studied extensively...
A new algorithm to predict warfarin dose from polymorphisms of CYP4F2 , CYP2C9 and VKORC1 and clinical variables: derivation in Han Chinese patients with non valvular atrial fibrillationMeng Wei
Department of Clinical Pharmacology, Nanjing First Hospital, Nanjing Medical University, 68 Changle Road, Nanjing, Jiangsu 210006, China
Thromb Haemost 107:1083-91. 2012..The algorithm developed by us might predict warfarin dose used by Chinese NVAF patients...
Favorable effects of resveratrol on sympathetic neural remodeling in rats following myocardial infarctionPing Xin
Division of Cardiology, Shanghai Sixth Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China
Eur J Pharmacol 649:293-300. 2010....
Thorombolytic therapy with rescue percutaneous coronary intervention versus primary percutaneous coronary intervention in patients with acute myocardial infarction: a multicenter randomized clinical trialRun lin Gao
Department of Cardiology, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences, Beijing 100037, China
Chin Med J (Engl) 123:1365-72. 2010....
Efficacy and tolerability of a single-pill combination of amlodipine/valsartan in Asian hypertensive patients not adequately controlled with valsartan monotherapyJun Huang
The First Affiliated Hospital with Nanjing Medical University, Nanjing, China
Clin Exp Hypertens 33:179-86. 2011..1-58.6%) monotherapies. The combination was well tolerated. In conclusion, single-pill combination with Aml/Val provided significant additional BP reduction and control in hypertensive patients not responding to Val 80 mg...
Fabrication of stents with endothelial function in vitroQing Zhao
Department of Cardiology, Shanghai Sixth People s Hospital, Shanghai Jiao Tong University, 200233, China
Scand Cardiovasc J 44:76-81. 2010..The aim of the study is to fabricate stents with rabbit outgrowth endothelial progenitor cells (OECs) to facilitate their endothelial function in vitro...
Rac1 signalling mediates doxorubicin-induced cardiotoxicity through both reactive oxygen species-dependent and -independent pathwaysJian Ma
Department of Cardiology, Shanghai 6th People s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200233, China
Cardiovasc Res 97:77-87. 2013..This study investigated the role of Rac1, an important subunit of NADPH oxidase, in doxorubicin-induced cardiotoxicity and the underlying mechanisms...
[Evaluation of the myocardial protection of trimetazidine during percutaneous coronary intervention: a multi-center randomized and controlled clinical study]Yun Dai Chen
Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China
Zhonghua Nei Ke Za Zhi 49:473-6. 2010..To evaluate the myocardial protection effects of trimetazidine during percutaneous coronary intervention (PCI)...
[Effects of pravastatin, fosinopril and their combination on myocardium TNF-alpha expression and ventricular remodeling after myocardial infarction in rats]Meng Wei
Department of Cardiology, Shanghai Jiaotong University Affiliated No 6 Hospital, Shanghai 200233, China
Zhonghua Xin Xue Guan Bing Za Zhi 33:444-7. 2005....
[Cardiac mast cells accumulation and degranulation contribute to collagen deposition after coronary microembolization]Qing Yong Zhang
Department of Cardiology, the NO 6 People s Hospital, Shanghai Jiaotong University, Shanghai 200233, China
Zhejiang Da Xue Xue Bao Yi Xue Ban 39:187-92. 2010..To investigate potential pathophysiological role of cardiac mast cells accumulation and degranulation on the collagen deposition after coronary microembolization (CME)...
Simvastatin attenuates sympathetic hyperinnervation to prevent atrial fibrillation during the postmyocardial infarction remodeling processTao Yu
Division of Cardiology, Shanghai Sixth Hospital, Shanghai Jiaotong University School of Medicine, State Key Discipline Division, Shanghai, China
J Appl Physiol 113:1937-44. 2012..These data suggest that simvastatin administration after MI can prevent AF through reduced sympathetic hyperinnervation...
Rationale and design of the beta-blocker in heart failure with normal left ventricular ejection fraction (beta-PRESERVE) studyJingmin Zhou
Department of Cardiology, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, Shanghai, China
Eur J Heart Fail 12:181-5. 2010..However, few studies have been conducted in this population and no proven treatment is available. Although beta-blockers are evidence-based first-line therapy in systolic heart failure, they have not been well studied in HFNEF...
[Long-term outcomes after elective coronary stenting in diabetic patients]Li Jiang
Department of Cardiology, Shanghai Sixth People s Hospital, Shanghai Jiaotong University, Shanghai 200233, China
Zhonghua Nei Ke Za Zhi 43:433-5. 2004..To observe the long-term outcomes following coronary stenting in diabetic patients with coronary artery disease...
[Effects of intensive clinic follow-up on short-term outcome of outpatients with chronic heart failure]Ming ya Liu
Department of Cardiology, Shanghai Sixth People s Hospital Affiliated to Shanghai Jiaotong University, Shanghai 200233, China
Zhonghua Xin Xue Guan Bing Za Zhi 38:588-91. 2010..To test the efficacy of intensive clinic follow-up for outpatients with chronic heart failure (CHF) on outcome...
