Heng Xiang Wang

Summary

Country: China

Publications

  1. doi Haploidentical hematopoietic stem cell transplantation in hematologic malignancies with G-CSF mobilized bone marrow plus peripheral blood stem cells grafts without T cell depletion: a single center report of 29 cases
    Heng Xiang Wang
    Department of Hematology, The General Hospital of Air Force, Beijing, China
    Leuk Lymphoma 53:654-9. 2012
  2. ncbi [Application of fibrotic bronchoscopy in the diagnosis of pulmonary diffuse infiltration following bone marrow transplantation]
    Heng Xiang Wang
    Department of Hematology, The General Hospital of Air Force, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 16:946-9. 2008
  3. ncbi [Clinical study of a new protocol for acute graft-versus host disease prophylaxis in HLA-haploidentical bone marrow transplantation (BMT)]
    Shu Quan Ji
    Department of Hematology, The General Hospital of Air Force PLA, Beijing 100036, China
    Zhonghua Xue Ye Xue Za Zhi 24:416-9. 2003
  4. ncbi [CD25 monoclonal antibody for GVHD prophylaxis in non-T-cell depleted haploidentical bone marrow transplantation for treatment of childhood leukemia]
    Hui Ren Chen
    Department of Hematology, The General Hospital of PLA Air Force, Beijing 100036, China
    Zhonghua Er Ke Za Zhi 42:294-8. 2004
  5. ncbi [A clinical study of haploidentical and G-CSF primed bone marrow transplantation by using CD25 for aGVHD prophylaxis]
    Shu Quan Ji
    Department of Hematology, The General Hospital of Air Force PLA, Beijing, 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 10:447-51. 2002
  6. ncbi Humanized anti-CD25 monoclonal antibody for prophylaxis of graft-vs-host disease (GVHD) in haploidentical bone marrow transplantation without ex vivo T-cell depletion
    Hui Ren Chen
    Research Institution Of Air Force Hematology PLA, Beijing, China
    Exp Hematol 31:1019-25. 2003
  7. ncbi [Haploidentical allogeneic bone marrow stem cell transplantation combined with peripheral blood stem cells for therapy of leukemia]
    Hong Min Yan
    Department of Hematology, Air Force General Hospital, Chinese PLA, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 17:1330-4. 2009
  8. ncbi [Successful engraftment of T-cell undepleted haploidentical transplants by donor primed with G-CSF and additional use of ATG and MMF for recipients]
    Hui Ren Chen
    Research Centre for Hematology, The General Hospital of Air Force, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 10:548-52. 2002
  9. ncbi [Clinical study on hematopoietic reconstitution in patients with leukemia by haploidentical bone marrow transplantation]
    Heng Xiang Wang
    Department of Hematology, The General Hospital of Air Force, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 11:416-9. 2003
  10. doi Haploidentical hematopoietic stem cell transplantation in child hematologic malignancies with G-CSF-mobilized marrow grafts without T-cell depletion: a single-center report of 45 cases
    Heng Xiang Wang
    Department of Hematology, The General Hospital of the Air Force, PLA, Beijing, China
    Pediatr Hematol Oncol 26:119-28. 2009

Collaborators

Detail Information

Publications31

  1. doi Haploidentical hematopoietic stem cell transplantation in hematologic malignancies with G-CSF mobilized bone marrow plus peripheral blood stem cells grafts without T cell depletion: a single center report of 29 cases
    Heng Xiang Wang
    Department of Hematology, The General Hospital of Air Force, Beijing, China
    Leuk Lymphoma 53:654-9. 2012
    ..2%. These results suggest that G-CSF-primed bone marrow plus peripheral blood stem cell grafts are an appropriate stem cell source for Haplo-HSCT and large scale investigations are needed to confirm this protocol...
  2. ncbi [Application of fibrotic bronchoscopy in the diagnosis of pulmonary diffuse infiltration following bone marrow transplantation]
    Heng Xiang Wang
    Department of Hematology, The General Hospital of Air Force, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 16:946-9. 2008
    ..Furthermore, TBLB should be recommended in order to avoid open lung biopsy, if the patients tolerate the operation...
  3. ncbi [Clinical study of a new protocol for acute graft-versus host disease prophylaxis in HLA-haploidentical bone marrow transplantation (BMT)]
    Shu Quan Ji
    Department of Hematology, The General Hospital of Air Force PLA, Beijing 100036, China
    Zhonghua Xue Ye Xue Za Zhi 24:416-9. 2003
    ..To explore the feasibility of a new protocol for acute graft versus host disease (aGVHD) prophylaxis in haploidentical bone marrow transplantation...
  4. ncbi [CD25 monoclonal antibody for GVHD prophylaxis in non-T-cell depleted haploidentical bone marrow transplantation for treatment of childhood leukemia]
    Hui Ren Chen
    Department of Hematology, The General Hospital of PLA Air Force, Beijing 100036, China
    Zhonghua Er Ke Za Zhi 42:294-8. 2004
    ..The purpose of this study was to explore the effects of CD25 monoclonal antibody on reducing the incidence of severe acute GVHD in haploidentical bone marrow transplantation for the treatment of childhood leukemia...
  5. ncbi [A clinical study of haploidentical and G-CSF primed bone marrow transplantation by using CD25 for aGVHD prophylaxis]
    Shu Quan Ji
    Department of Hematology, The General Hospital of Air Force PLA, Beijing, 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 10:447-51. 2002
    ..The major histocompatibility barrier in the haploidentical related allo-BMT could be crossed by donors primed with G-CSF and GVHD prophylaxis with CD25 antibody in the hosts...
  6. ncbi Humanized anti-CD25 monoclonal antibody for prophylaxis of graft-vs-host disease (GVHD) in haploidentical bone marrow transplantation without ex vivo T-cell depletion
    Hui Ren Chen
    Research Institution Of Air Force Hematology PLA, Beijing, China
    Exp Hematol 31:1019-25. 2003
    ..To investigate the effects of a novel anti-IL-2 receptor (CD25) monoclonal antibody, basiliximab, on graft-vs-host disease (GVHD) and engraftment in haploidentical bone marrow transplantation (BMT)...
  7. ncbi [Haploidentical allogeneic bone marrow stem cell transplantation combined with peripheral blood stem cells for therapy of leukemia]
    Hong Min Yan
    Department of Hematology, Air Force General Hospital, Chinese PLA, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 17:1330-4. 2009
    ....
  8. ncbi [Successful engraftment of T-cell undepleted haploidentical transplants by donor primed with G-CSF and additional use of ATG and MMF for recipients]
    Hui Ren Chen
    Research Centre for Hematology, The General Hospital of Air Force, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 10:548-52. 2002
    ..This could be caused by the low overall incidence of aGVHD as a result of BM primed with G-CSF. The four-agent of immunosuppressive combined prophylaxis against GVHD in different periods may be highly effective...
  9. ncbi [Clinical study on hematopoietic reconstitution in patients with leukemia by haploidentical bone marrow transplantation]
    Heng Xiang Wang
    Department of Hematology, The General Hospital of Air Force, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 11:416-9. 2003
    ....
  10. doi Haploidentical hematopoietic stem cell transplantation in child hematologic malignancies with G-CSF-mobilized marrow grafts without T-cell depletion: a single-center report of 45 cases
    Heng Xiang Wang
    Department of Hematology, The General Hospital of the Air Force, PLA, Beijing, China
    Pediatr Hematol Oncol 26:119-28. 2009
    ..The total disease-free survival rate longer than 2 years was 53.3%. These data suggest that haploidentical hematopoietic transplantation is an alterative strategy for children who lack immediate access to HLA-matched sources...
  11. ncbi Impact of incompatible killer cell immunoglobulin-like receptor and its ligand on the outcome of haploidentical bone marrow transplantation
    Lian Ning Duan
    Department of Hematology, General Hospital of Air Force, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 15:809-15. 2007
    ..The missing ligand for the donor KIR has strong effect on the outcome of BMT and it means a lot to analyze the KIR genotype and its ligand for the selection of best donor and prognostic evaluation in haploidentical BMT...
  12. ncbi [Antithymocyte globulin used for treatment of severe acute graft versus host disease after haploidentical bone marrow transplantation]
    Jing Liu
    Department of Hematology, Air Force General Hospital of PLA, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 15:816-8. 2007
    ..In conclusion, low-dose ATG is effective for some patients with steroid-resistant severe aGVHD, and has not severe side effect. To strengthen environmental protection should be considered as important for prevention of infection...
  13. ncbi Haploidentical hematopoietic stem-cell transplantation for non-Hodgkin lymphoma with bone marrow involvement
    Heng Xiang Wang
    Department of Hematology, The General Hospital of Air Force, Beijing, China
    Leuk Lymphoma 50:1488-93. 2009
    ..71 months (range: 44-81 months). The results here suggest that haplo-HSCT might provide an opportunity of myeloablative therapy for refractory lymphoma with marrow infiltration...
  14. ncbi [Neurological complications following haploidentical bone marrow transplantation]
    Heng Xiang Wang
    Department of Hemotology, General Hospital of Air Force, PLA, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 13:1128-30. 2005
    ..Moreover, central nerve system infection and peripheral nerve diseases associated with slow immune reconstitution should have clinical interests...
  15. ncbi [Pulmonary complications in haploidentical bone marrow transplantation]
    Heng Xiang Wang
    Department of Hematology, General Hospital of Air Force, PLA, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 12:185-7. 2004
    ..In conclusion: pulmonary complications were commonly seen in haploidentcal bone marrow transplantation, and fungal pneumonia might be the main cause that needs intensive management...
  16. ncbi [Clinical investigation on treatment of children leukemia with non-T-cell depleted haploidentical bone marrow transplantation]
    Hong Ming Yan
    Department of Hematology, The General Hospital of Air Force, Center of PLA Haploidentical Bone Marrow Transplantation, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 16:101-5. 2008
    ....
  17. ncbi [Clinical research on reconstitution of CD4+CD25+ T cells after haploidentical bone marrow transplantation]
    Lian Nng Duan
    Department of Hematology, Air Force General Hospital of Chinese PLA, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 18:177-80. 2010
    ..Further investigation is needed to clarify whether the relapse of leukemia after hiBMT is related to the reconstitution of CD4(+)CD25(+) T cells...
  18. ncbi [Allogeneic hematopoietic stem cell transplantation in 6 patients with myelodysplastic syndrome]
    Mei Xue
    Department of Hematology, PLA Air Force General Hospital, Beijing, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 17:719-22. 2009
    ..During 18 - 108 months of following-up, 2 cases died of pulmonary complication and of relapse; the other 4 cases survive in a disease-free situation. In conclusion, allo-HSCT was an effective approach for the treatment of MDS...
  19. ncbi [Factors impacting yield of CD34(+) cells from healthy donors mobilized with rhG-CSF]
    Ling Zhu
    Department of Hematology, Air Force General Hospital, Chinese PLA, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 17:1541-5. 2009
    ....
  20. ncbi [Efficacy of anti-CD25 monoclonal antibody used in treating steroid-resistant acute graft-versus-host disease following haploidentical bone marrow transplantation]
    Jing Liu
    Department of Hematology, Air Force General Hospital, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 17:160-3. 2009
    ..Infection is the main cause of death. Thereby, it is especially important to strengthen environmental protection and prevent infection...
  21. ncbi [Donor peripheral blood mononuclear cell infusion (DMNCI) for treatment of patients with relapsed leukemia after haploidentical bone marrow transplantation]
    Mei Xue
    Department of Hematology, General Hospital of PLA Air Force, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 15:819-22. 2007
    ....
  22. ncbi Functional mesenchymal stem cells remain present in bone marrow microenvironment of patients with leukemia post-allogeneic hematopoietic stem cell transplant
    Li Ding
    Department of Hematology, General Hospital of the Air Force, PLA, Beijing, China
    Leuk Lymphoma 55:1635-44. 2014
    ..The results indicate that functional MSCs remain present in the BM microenvironment, and these findings shed light on the understanding of BM microenvironment reconstitution post-HSCT. ..
  23. ncbi [Nocardial infection after allogeneic hematopoietic stem cell transplantation]
    Jing Liu
    Department of Hematology, Air Force General Hospital, PLA Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 17:1339-41. 2009
    ..The culture of BAL fluid is helpful for its diagnosis and this disease might be sensitive to the treatment of TMP-SMZ-containing regimens...
  24. ncbi [Detection of bcr/abl fusion gene changes in patients with chronic myeloid leukemia after allo-HSCT by real-time quantitative reverse transcription polymerase chain reaction and its significance]
    Mei Xue
    Department of Hematology, Air Force General Hospital, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 16:1350-3. 2008
    ..It is concluded that serial quantifications of bcr/abl mRNA levels by RQ-PCR are reliable and can be used to detect the MRD, to monitor the outcome and to predict the relapse...
  25. ncbi [Acute leukemia relapse of donor origin in two cases after haploidentical bone marrow transplantation]
    Ling Zhu
    Department of Hematology, General Hospital of Air Forces, Beijing 100036, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 14:400-2. 2006
    ..Donor-cell leukemia after allogeneic hematopoietic stem cell transplantation can be an ideal model to investigate the related events in human leukemogenesis...
  26. ncbi [Analysis of T lymphocyte absolute number and function in the early phase after haploidentical hematopoietic stem cell transplantation]
    Li Ding
    Department of Experimental Hematology, Beijing Institute of Radiation Medicine, Beijing, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 21:702-6. 2013
    ..However, T cell function recovers to normal range at month 3 after transplantation. ..
  27. ncbi [Effect of microRNA-17-92 cluster on the biological characteristics of K562 cells and its mechanisms]
    Shuang Yang
    Department of Hematology, Dalian Medical University, Dalian 116044, Liaoning Province, China Department of Hematology, General Hospital of Chinese Air Force, Beijing 1000142, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 22:20-4. 2014
    ..The expression of signal connector protein Crk was greatly up-regulated in miR-17-92-mimic-transfected K562 cells. It is concluded that miR-17-92 can promote proliferation, inhibit apoptosis and regulate the cell cycle of K562 cells. ..
  28. pmc Microvesicles derived from human umbilical cord mesenchymal stem cells stimulated by hypoxia promote angiogenesis both in vitro and in vivo
    Hong Chao Zhang
    Department of Cardiology Surgery, General Hospital of Air Force, Beijing, China
    Stem Cells Dev 21:3289-97. 2012
    ..0001), as assessed by laser Doppler imaging analysis. These data indicate that MV releasing is one of the major mechanisms underlying the effectiveness of MSC therapy by promoting angiogenesis...
  29. ncbi [Effects of tumor necrosis factor-α on immunoregulatory activities of mesenchymal stem cells in vitro and in vivo]
    Yong Qi Wang
    Department of Hematoloyg, General Hospital of Chinese Air Force, Beijing, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 20:981-4. 2012
    ..05). It is concluded that the TNF-α exhibits different effects on immune regulation activity of MSC, and its underlying mechanism needs to further investigate...
  30. doi The epigenetically-regulated miR-663 targets H-ras in K-562 cells
    Yang Yang
    Department of Haematology and BMT Centre, Chinese PLA General Hospital, Beijing, China Department of Haematology, Chinese PLA Air Force General Hospital, Beijing, China
    FEBS J 280:5109-17. 2013
    ..Over-expression of miR-663 may suppress proliferation of the k-562 cell line in part by enhancing cell apoptosis. ..
  31. ncbi [Human bone marrow mesenchymal stem cells have little preventive or therapeutic effect on rat arthritis induced by collagen]
    Yong Qi Wang
    Department of Hematology, General Hospital of Chinese Air Force, Beijing, China
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 20:433-7. 2012
    ..It is concluded that MSC infusion has little beneficial effects on collagen-induced arthritis in rats, conversely, MSC therapy aggravated the damage of the involved joints, its underlying mechanisms need to be further investigated...