Wang J, Luo H, Yang L, Li Y. Baicalein induces apoptosis and reduces inflammation in LPS-stimulated keratinocytes by blocking the activation of NF-?B: implications for alleviating oral lichen planus. Cell Mol Biol (Noisy-le-grand). 2016;62:55-60 pubmed
..Our findings suggest that BAI inhibits the production of inflammatory cytokines by negatively regulating the NF-?B signaling pathway under LPS simulation in HaCaT cells. ..
Wang J, Luo H, Xiao Y, Wang L. miR-125b inhibits keratinocyte proliferation and promotes keratinocyte apoptosis in oral lichen planus by targeting MMP-2 expression through PI3K/Akt/mTOR pathway. Biomed Pharmacother. 2016;80:373-380 pubmed publisher
..Taken together, these data confirm that miR-125b might inhibit keratinocyte proliferation and promote keratinocyte apoptosis in OLP pathogenesis by targeting MMP-2 through PI3K/Akt/mTOR pathway. ..
Liu Y, Liu G, Zhang H, Wang J. MiRNA-199a-5p influences pulmonary artery hypertension via downregulating Smad3. Biochem Biophys Res Commun. 2016;473:859-866 pubmed publisher
..Our date suggest that miR-199a-5p may function as a regulator of PAH by targeting Smad3, indicating a novel therapeutic strategy for patients with PAH. ..
Wang J, Xin L, Cheng W, Wang Z, Zhang W. [Effect of heat shock factor 1 on airway hyperresponsiveness and airway inflammation in mice with allergic asthma]. Zhongguo Dang Dai Er Ke Za Zhi. 2017;19:222-228 pubmed
..05). Knockdown of HSF1 aggravates airway hyperresponsiveness and airway inflammation in asthmatic mice, and its possible mechanism may involve the negative regulation of HMGB1 and JNK. ..