Kwok Yung Yuen

Summary

Affiliation: University of Hong Kong
Country: China

Publications

  1. pmc SARS coronavirus detection methods
    Susanna K P Lau
    Department of Microbiology, University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of China
    Emerg Infect Dis 11:1108-11. 2005
  2. ncbi request reprint Wild animal surveillance for coronavirus HKU1 and potential variants of other coronaviruses
    K Y Yuen
    Department of Microbiology, The University of Hong Kong Queen Mary Hospital, Hong Kong SAR, China
    Hong Kong Med J 18:25-6. 2012
  3. pmc Laribacter hongkongensis gen. nov., sp. nov., a novel gram-negative bacterium isolated from a cirrhotic patient with bacteremia and empyema
    K Y Yuen
    Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 39:4227-32. 2001
  4. pmc Typhoid fever associated with acute appendicitis caused by an H1-j strain of Salmonella enterica serotype Typhi
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 43:1470-2. 2005
  5. ncbi request reprint Human infection by avian influenza A H5N1
    K Y Yuen
    Department of Microbiology, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Hong Kong Med J 11:189-99. 2005
  6. pmc Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in sars patients by enzyme-linked immunosorbent assay
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 42:2884-9. 2004
  7. pmc False-positive results in a recombinant severe acute respiratory syndrome-associated coronavirus (SARS-CoV) nucleocapsid enzyme-linked immunosorbent assay due to HCoV-OC43 and HCoV-229E rectified by Western blotting with recombinant SARS-CoV spike polypep
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 42:5885-8. 2004
  8. pmc Life-threatening invasive Helcococcus kunzii infections in intravenous-drug users and ermA-mediated erythromycin resistance
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 43:6205-8. 2005
  9. doi request reprint Lichtheimia hongkongensis sp. nov., a novel Lichtheimia spp. associated with rhinocerebral, gastrointestinal, and cutaneous mucormycosis
    Patrick C Y Woo
    State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong
    Diagn Microbiol Infect Dis 66:274-84. 2010
  10. ncbi request reprint An oral mucosal DNA vaccine for SARS coronavirus infections
    K Y Yuen
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong SAR, China
    Hong Kong Med J 15:41-2. 2009

Collaborators

Detail Information

Publications108 found, 100 shown here

  1. pmc SARS coronavirus detection methods
    Susanna K P Lau
    Department of Microbiology, University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of China
    Emerg Infect Dis 11:1108-11. 2005
    ....
  2. ncbi request reprint Wild animal surveillance for coronavirus HKU1 and potential variants of other coronaviruses
    K Y Yuen
    Department of Microbiology, The University of Hong Kong Queen Mary Hospital, Hong Kong SAR, China
    Hong Kong Med J 18:25-6. 2012
    ..5. This study also revealed a previously unknown diversity of coronaviruses in bats, which are important natural reservoir for coronaviruses including SARS-CoV-like viruses...
  3. pmc Laribacter hongkongensis gen. nov., sp. nov., a novel gram-negative bacterium isolated from a cirrhotic patient with bacteremia and empyema
    K Y Yuen
    Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 39:4227-32. 2001
    ..nov., sp. nov., is proposed, for which HKU1 is the type strain. Further studies should be performed to ascertain the potential of this bacterium to become an emerging pathogen...
  4. pmc Typhoid fever associated with acute appendicitis caused by an H1-j strain of Salmonella enterica serotype Typhi
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 43:1470-2. 2005
    ..She recovered with appendectomy and antibiotic treatment. Further studies should be performed to determine the prevalence of this unusual S. enterica serotype Typhi strain in our locality...
  5. ncbi request reprint Human infection by avian influenza A H5N1
    K Y Yuen
    Department of Microbiology, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Hong Kong Med J 11:189-99. 2005
    ....
  6. pmc Detection of severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in sars patients by enzyme-linked immunosorbent assay
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 42:2884-9. 2004
    ..Further studies on serial clinical specimens should reveal the duration of nucleocapsid protein shedding and may reveal a higher detection rate in SARS patients...
  7. pmc False-positive results in a recombinant severe acute respiratory syndrome-associated coronavirus (SARS-CoV) nucleocapsid enzyme-linked immunosorbent assay due to HCoV-OC43 and HCoV-229E rectified by Western blotting with recombinant SARS-CoV spike polypep
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 42:5885-8. 2004
    ..None of these samples were found to contain a specific antibody in the recombinant SARS-CoV spike polypeptide-based Western blot assay...
  8. pmc Life-threatening invasive Helcococcus kunzii infections in intravenous-drug users and ermA-mediated erythromycin resistance
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 43:6205-8. 2005
    ..Gram smears of both H. kunzii isolates showed a mixture of gram-positive and gram-negative cocci. The isolate from the first patient, resistant to erythromycin and clindamycin, possessed an ermA gene...
  9. doi request reprint Lichtheimia hongkongensis sp. nov., a novel Lichtheimia spp. associated with rhinocerebral, gastrointestinal, and cutaneous mucormycosis
    Patrick C Y Woo
    State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong
    Diagn Microbiol Infect Dis 66:274-84. 2010
    ..to describe this fungus, which caused rhinocerebral, gastrointestinal, and cutaneous mucormycosis, respectively, in 3 patients. A significant proportion of L. corymbifera associated with mucormycosis reported may be L. hongkongensis...
  10. ncbi request reprint An oral mucosal DNA vaccine for SARS coronavirus infections
    K Y Yuen
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong SAR, China
    Hong Kong Med J 15:41-2. 2009
    ..3. This study indicates that the type of vaccine used for priming is crucial for determining the type of immune response developed.Subsequent doses will boost the immune response generated by the first dose of vaccine...
  11. pmc Natural selection retains overrepresented out-of-frame stop codons against frameshift peptides in prokaryotes
    Herman Tse
    Carol Yu Centre for Infection, Department of Microbiology, The University of Hong Kong, Hong Kong, China
    BMC Genomics 11:491. 2010
    ..Given such a functional significance, we expect statistically overrepresented OSCs in coding sequences as a result of a widespread selection. Accordingly, we examined available prokaryotic genomes to look for evidence of this selection...
  12. ncbi request reprint SARS coronavirus spike polypeptide DNA vaccine priming with recombinant spike polypeptide from Escherichia coli as booster induces high titer of neutralizing antibody against SARS coronavirus
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, Room 423, University Pathology Building, Queen Mary Hospital, Hong Kong
    Vaccine 23:4959-68. 2005
    ..The present observation may have major practical value, such as immunization of civet cats, since production of recombinant proteins from E. coli is far less expensive than production of recombinant proteins using eukaryotic systems...
  13. pmc Coronavirus HKU1 and other coronavirus infections in Hong Kong
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 44:2063-71. 2006
    ..Similar studies in other countries are required to better determine the epidemiology and genetic diversity of CoV-HKU1...
  14. ncbi request reprint Relative rates of non-pneumonic SARS coronavirus infection and SARS coronavirus pneumonia
    Patrick C Y Woo
    Department of Microbiology, University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    Lancet 363:841-5. 2004
    ....
  15. ncbi request reprint Clinical and molecular epidemiological features of coronavirus HKU1-associated community-acquired pneumonia
    Patrick C Y Woo
    Division of Infectious Disease, Department of Microbiology, The University of Hong Kong, Hong Kong, China
    J Infect Dis 192:1898-907. 2005
    ..Recently, we described the discovery of a novel group 2 coronavirus, coronavirus HKU1 (CoV-HKU1), from a patient with pneumonia. However, the clinical and molecular epidemiological features of CoV-HKU1-associated pneumonia are unknown...
  16. ncbi request reprint Clinical and molecular epidemiology of human bocavirus in respiratory and fecal samples from children in Hong Kong
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, University of Hong Kong, Hong Kong, China
    J Infect Dis 196:986-93. 2007
    ..We conducted the first systematic prospective clinical and molecular study using nasopharyngeal aspirates (NPAs) and fecal samples...
  17. ncbi request reprint Clinical deterioration in community acquired infections associated with lymphocyte upsurge in immunocompetent hosts
    Vincent C C Cheng
    Division of Infectious Diseases, Centre of Infection Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China
    Scand J Infect Dis 36:743-51. 2004
    ..05). We postulate that the peripheral lymphocyte count may be a useful surrogate marker indicating the presence of immunopathological damage during clinical deterioration in certain infectious diseases...
  18. pmc Molecular epidemiology of human coronavirus OC43 reveals evolution of different genotypes over time and recent emergence of a novel genotype due to natural recombination
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Virol 85:11325-37. 2011
    ....
  19. ncbi request reprint A novel approach for screening immunogenic proteins in Penicillium marneffei using the DeltaAFMP1DeltaAFMP2 deletion mutant of Aspergillus fumigatus
    Patrick C Y Woo
    Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
    FEMS Microbiol Lett 262:138-47. 2006
    ..marneffei infection. A similar approach could be applied to immunogenic protein screening in other microorganisms for serological diagnosis, epidemiological studies and the study of vaccines...
  20. pmc Detection of specific antibodies to severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein for serodiagnosis of SARS coronavirus pneumonia
    Patrick C Y Woo
    Department of Microbiology, University of Hong Kong, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 42:2306-9. 2004
    ..The present ELISA appears to be a sensitive test for serodiagnosis of SARS-CoV pneumonia, is much more economical and less labor-intensive than the indirect immunofluorescence assay, and does not require cultivation of SARS-CoV...
  21. ncbi request reprint Association of Laribacter hongkongensis in community-acquired gastroenteritis with travel and eating fish: a multicentre case-control study
    Patrick C Y Woo
    Department of Microbiology, University of Hong Kong, University Pathology Building, Queen Mary Hospital, Pokfulam, Hong Kong, People s Republic of China
    Lancet 363:1941-7. 2004
    ..We undertook a multicentre case-control study to investigate the association of L hongkongensis with gastroenteritis...
  22. pmc Cloning and characterization of a chromosomal class C beta-lactamase and its regulatory gene in Laribacter hongkongensis
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, Hong Kong
    Antimicrob Agents Chemother 49:1957-64. 2005
    ..The beta-lactamase characterized from strain HLHK5 was named LHK-5 (gene, bla(LHK-5)) and represents the first example of AmpC beta-lactamase in the beta subdivision of proteobacteria...
  23. ncbi request reprint Anaerospora hongkongensis gen. nov. sp. nov., a novel genus and species with ribosomal DNA operon heterogeneity isolated from an intravenous drug abuser with pseudobacteremia
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital Compound, Hong Kong
    Microbiol Immunol 49:31-9. 2005
    ..hippei and P. vibrioides. The G+C content of the bacterium (mean +/- SD) was 46.8 +/- 3.2%. For these reasons, a new genus and species, Anaerospora hongkongensis gen. nov. sp. nov., is proposed, for which HKU15T is the type strain...
  24. ncbi request reprint Characterization of a novel cryptic plasmid, pHLHK26, in Laribacter hongkongensis
    Patrick C Y Woo
    Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
    New Microbiol 30:139-47. 2007
    ....
  25. pmc Differential sensitivities of severe acute respiratory syndrome (SARS) coronavirus spike polypeptide enzyme-linked immunosorbent assay (ELISA) and SARS coronavirus nucleocapsid protein ELISA for serodiagnosis of SARS coronavirus pneumonia
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Pokfulam, Hong Kong
    J Clin Microbiol 43:3054-8. 2005
    ..2%) (P < 0.01). An ELISA for detection of IgM against S and N could be more sensitive than one that detects IgM against N alone for serodiagnosis of SARS-CoV pneumonia...
  26. pmc Initial viral load and the outcomes of SARS
    Chung Ming Chu
    Department of Microbiology, Queen Mary Hospital, The University of Hong Kong, China
    CMAJ 171:1349-52. 2004
    ..Preliminary data suggest that a high viral load of the SARS coronavirus is associated with adverse outcomes in the intensive care unit, but the relation of viral load to survival is unclear...
  27. ncbi request reprint Bacteremia in a patient with colonic carcinoma caused by a novel Sedimentibacter species: Sedimentibacter hongkongensis sp. nov
    Patrick C Y Woo
    Department of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
    Diagn Microbiol Infect Dis 50:81-7. 2004
    ..9% differences between the 16S rRNA gene sequence of the bacterium and those of S. hydroxybenzoicus and S. saalensis respectively. A new species, Sedimentibacter hongkongenesis sp. nov., is proposed, for which HKU2(T) is the type strain...
  28. pmc Longitudinal profile of immunoglobulin G (IgG), IgM, and IgA antibodies against the severe acute respiratory syndrome (SARS) coronavirus nucleocapsid protein in patients with pneumonia due to the SARS coronavirus
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, Hong Kong
    Clin Diagn Lab Immunol 11:665-8. 2004
    ..Further studies should be performed to see whether SARS-CoV nucleocapsid protein antibody positivity has any prognostic significance...
  29. ncbi request reprint Eggerthella hongkongensis sp. nov. and eggerthella sinensis sp. nov., two novel Eggerthella species, account for half of the cases of Eggerthella bacteremia
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    Diagn Microbiol Infect Dis 49:255-63. 2004
    ..The present study suggests that Eggerthella bacteremia is much more common than expected and is associated with significant morbidity and mortality. Moreover, the 2 novel species account for half of the cases of Eggerthella bacteremia...
  30. ncbi request reprint Streptococcus sinensis may react with Lancefield group F antiserum
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Med Microbiol 53:1083-8. 2004
    ..3 % S. anginosus, respectively. The present data revealed that a proportion of Lancefield group F streptococci could be S. sinensis. Lancefield group F streptococci should not be automatically reported as 'S. milleri'...
  31. doi request reprint Proteome profiling of the dimorphic fungus Penicillium marneffei extracellular proteins and identification of glyceraldehyde-3-phosphate dehydrogenase as an important adhesion factor for conidial attachment
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, Research Centre of Infection and Immunology and Carol Yu Centre for Infection, University of Hong Kong, China Department of Microbiology, University of Hong Kong, China
    FEBS J 280:6613-26. 2013
    ..This report demonstrates GAPDH as an adherence factor in P. marneffei by mediating conidia adherence to host bronchoalveolar epithelium during the early establishment phase of infection. ..
  32. ncbi request reprint Recombinant adeno-associated virus expressing the receptor-binding domain of severe acute respiratory syndrome coronavirus S protein elicits neutralizing antibodies: Implication for developing SARS vaccines
    Lanying Du
    Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Virology 353:6-16. 2006
    ..5 months. These results suggested that RBD-rAAV is a promising SARS candidate vaccine...
  33. pmc Detection of antibodies specific to an antigenic cell wall galactomannoprotein for serodiagnosis of Aspergillus fumigatus aspergillosis
    Che Man Chan
    Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 40:2041-5. 2002
    ..Thus, this ELISA-based test for the detection of anti-Afmp1p antibody can be of significant value as a diagnostic for aspergillosis...
  34. pmc Discovery of seven novel Mammalian and avian coronaviruses in the genus deltacoronavirus supports bat coronaviruses as the gene source of alphacoronavirus and betacoronavirus and avian coronaviruses as the gene source of gammacoronavirus and deltacoronavi
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, Hong Kong, and Guangzhou Center for Disease Control and Prevention, Guangzhou, China
    J Virol 86:3995-4008. 2012
    ....
  35. pmc Intranasal vaccination of recombinant adeno-associated virus encoding receptor-binding domain of severe acute respiratory syndrome coronavirus (SARS-CoV) spike protein induces strong mucosal immune responses and provides long-term protection against SARS-
    Lanying Du
    Department of Microbiology, University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China
    J Immunol 180:948-56. 2008
    ..n. vaccination may be the preferred route of administration due to its ability to induce SARS-CoV-specific systemic and mucosal immune responses and its better safety profile...
  36. pmc Use of cefoperazone MacConkey agar for selective isolation of Laribacter hongkongensis
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, Hong Kong
    J Clin Microbiol 41:4839-41. 2003
    ..In addition, with CMA, Arcobacter butzleri was unexpectedly isolated from the stools of six patients...
  37. ncbi request reprint Identification and complete genome analysis of three novel paramyxoviruses, Tuhoko virus 1, 2 and 3, in fruit bats from China
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, Hong Kong, China
    Virology 404:106-16. 2010
    ..Analysis of phosphoprotein gene mRNA products confirmed mRNA editing. Antibodies to the viruses were detected in 48-60% of Leschenault's rousettes...
  38. ncbi request reprint NF90 exerts antiviral activity through regulation of PKR phosphorylation and stress granules in infected cells
    Xi Wen
    State Key Laboratory for Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of China
    J Immunol 192:3753-64. 2014
    ..Taken together, these results reveal a yet-to-be defined host antiviral mechanism in which NF90 upregulation of PKR phosphorylation restricts virus infection. ..
  39. pmc Genetic characterization of Betacoronavirus lineage C viruses in bats reveals marked sequence divergence in the spike protein of pipistrellus bat coronavirus HKU5 in Japanese pipistrelle: implications for the origin of the novel Middle East respiratory sy
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, China
    J Virol 87:8638-50. 2013
    ..Intensive surveillance for lineage C betaCoVs in Pipistrellus and related bats with diverse habitats and other animals in the Middle East may fill the evolutionary gap. ..
  40. pmc Coexistence of different genotypes in the same bat and serological characterization of Rousettus bat coronavirus HKU9 belonging to a novel Betacoronavirus subgroup
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, Research Centre of Infection and Immunology, Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong, China
    J Virol 84:11385-94. 2010
    ..Such unique phenomena, and the unusual instability of ORF7a, are likely due to recombination which may have been facilitated by the dense roosting behavior and long foraging range of Leschenault's rousette...
  41. pmc Characterization and complete genome sequence of a novel coronavirus, coronavirus HKU1, from patients with pneumonia
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Virol 79:884-95. 2005
    ..13 x 10(6) copies per ml, from a 35-year-old woman with pneumonia. Our data support the existence of a novel group 2 coronavirus associated with pneumonia in humans...
  42. ncbi request reprint Actinomyces hongkongensis sp. nov. a novel Actinomyces species isolated from a patient with pelvic actinomycosis
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, Hong Kong
    Syst Appl Microbiol 26:518-22. 2003
    ..nov., is proposed, for which HKU8(T) is the type strain. Further studies should be performed to ascertain the potential of this bacterium to become an important cause of actinomycosis...
  43. ncbi request reprint Clinical isolates of Streptococcus iniae from Asia are more mucoid and beta-hemolytic than those from North America
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, Hong Kong
    Diagn Microbiol Infect Dis 54:177-81. 2006
    ..iniae infection. The Asian population and handlers of fresh fish should be informed of the risk of acquiring S. iniae infection...
  44. pmc Comparative analysis of twelve genomes of three novel group 2c and group 2d coronaviruses reveals unique group and subgroup features
    Patrick C Y Woo
    State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Virol 81:1574-85. 2007
    ..Further molecular epidemiological studies on coronaviruses in the bats of other countries, as well as in other animals, and complete genome sequencing will shed more light on coronavirus diversity and their evolutionary histories...
  45. doi request reprint Spike protein, S, of human coronavirus HKU1: role in viral life cycle and application in antibody detection
    Che Man Chan
    Department of Microbiology, The University of Hong Kong, Hong Kong Special Administration Region, Hong Kong
    Exp Biol Med (Maywood) 233:1527-36. 2008
    ..The data suggest that the native form of HCoV-HKU1 spike expressed in our system can be used in developing serological diagnostic assay and in understanding the role of S in the viral life cycle...
  46. doi request reprint Delayed induction of proinflammatory cytokines and suppression of innate antiviral response by the novel Middle East respiratory syndrome coronavirus: implications for pathogenesis and treatment
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, University of Hong Kong, Hong Kong, P R China
    J Gen Virol 94:2679-90. 2013
    ..Our results provide insights into the pathogenesis and treatment of MERS-CoV infections. ..
  47. ncbi request reprint Diagnostic application of genotypic identification of mycobacteria
    Wing Cheong Yam
    Centre of Infection and Department of Microbiology, Queen Mary Hospital, The University of Hong Kong, China
    J Med Microbiol 55:529-36. 2006
    ....
  48. doi request reprint Identification and characterization of a novel paramyxovirus, porcine parainfluenza virus 1, from deceased pigs
    Susanna K P Lau
    Department of Microbiology, University of Hong Kong, Hong Kong, PR China
    J Gen Virol 94:2184-90. 2013
    ..The presence of PPIV-1 in mainly respiratory samples suggests a possible association with respiratory disease, similar to HPIV-1 and SeV. ..
  49. pmc Usefulness of the MicroSeq 500 16S ribosomal DNA-based bacterial identification system for identification of clinically significant bacterial isolates with ambiguous biochemical profiles
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 41:1996-2001. 2003
    ....
  50. ncbi request reprint Granulicatella adiacens and Abiotrophia defectiva bacteraemia characterized by 16S rRNA gene sequencing
    Patrick Chiu Yat Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Med Microbiol 52:137-40. 2003
    ..defectiva. 16S rRNA gene sequencing is the technique of choice for identifying G. adiacens and A. defectiva, and early surgical intervention should be considered when G. adiacens endocarditis is diagnosed...
  51. ncbi request reprint Polymorphisms of CCR5 gene in a southern Chinese population and their effects on disease progression in HIV infections
    Bo Jian Zheng
    HIV Research Laboratories, Department of Microbiology, The University of Hong Kong, Hong Kong, China
    AIDS 16:2480-2. 2002
  52. ncbi request reprint Seasonal and tissue distribution of Laribacter hongkongensis, a novel bacterium associated with gastroenteritis, in retail freshwater fish in Hong Kong
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, Hong Kong
    Int J Food Microbiol 113:62-6. 2007
    ..Proper handling of freshwater fish for cooking, especially the gills and gut, is recommended to prevent acquisition of L. hongkongensis, and other freshwater fish related infections...
  53. pmc Detection of cell wall galactomannoprotein Afmp1p in culture supernatants of Aspergillus fumigatus and in sera of aspergillosis patients
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 40:4382-7. 2002
    ..In conclusion, the combined Afmp1p antibody and antigen tests are highly sensitive and specific for A. fumigatus invasive aspergillosis...
  54. pmc Seronegative bacteremic melioidosis caused by Burkholderia pseudomallei with ambiguous biochemical profile: clinical importance of accurate identification by 16S rRNA gene and groEL gene sequencing
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 41:3973-7. 2003
    ..Sequencing of the groEL gene showed that the isolate was B. pseudomallei. Proper identification of the bacterium in this study is crucial, since there would be a radical difference in the duration of antimicrobial therapy...
  55. pmc Comparative analysis of 22 coronavirus HKU1 genomes reveals a novel genotype and evidence of natural recombination in coronavirus HKU1
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Virol 80:7136-45. 2006
    ..g., pol or helicase) and another from HE to N (e.g., spike or N). Further studies will delineate whether the ATR is useful for the molecular typing of CoV HKU1...
  56. ncbi request reprint Laribacter hongkongensis: a potential cause of infectious diarrhea
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, China
    Diagn Microbiol Infect Dis 47:551-6. 2003
    ..More extensive epidemiologic studies should be carried out to ascertain the causative association between L. hongkongensis and diarrhea and to define the reservoir and modes of transmission of L. hongkongensis...
  57. doi request reprint Phaeoacremonium parasiticum invasive infections and airway colonization characterized by agar block smear and ITS and β-tubulin gene sequencing
    Kelvin K W To
    Carol Yu Centre for Infection, The University of Hong Kong, Hong Kong, China
    Diagn Microbiol Infect Dis 74:190-7. 2012
    ..parasiticum. Cases of P. parasiticum infections should be confirmed by a polyphasic approach using morphologic characterization and ITS and β-tubulin gene sequencing...
  58. pmc Recent transmission of a novel alphacoronavirus, bat coronavirus HKU10, from Leschenault's rousettes to pomona leaf-nosed bats: first evidence of interspecies transmission of coronavirus between bats of different suborders
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong
    J Virol 86:11906-18. 2012
    ..This study provided the first evidence for interspecies transmission of coronavirus between bats of different suborders...
  59. doi request reprint Identification and characterization of bocaviruses in cats and dogs reveals a novel feline bocavirus and a novel genetic group of canine bocavirus
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, Hong Kong
    J Gen Virol 93:1573-82. 2012
    ..Although the pathogenicity of FBoV and CBoV remains to be determined, their presence in different host tissues suggested wide tissue tropism...
  60. doi request reprint Detection of human rhinovirus C in fecal samples of children with gastroenteritis
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, Hong Kong
    J Clin Virol 53:290-6. 2012
    ..Despite recent discovery of the novel human rhinovirus species, HRV-C, little is known about the association of HRV-C in diseases other than respiratory tract infections...
  61. doi request reprint Comparative analysis of six genome sequences of three novel picornaviruses, turdiviruses 1, 2 and 3, in dead wild birds, and proposal of two novel genera, Orthoturdivirus and Paraturdivirus, in the family Picornaviridae
    Patrick C Y Woo
    State Key Laboratory of Emerging Infectious Diseases, Hong Kong Special Administration Region, Hong Kong SAR
    J Gen Virol 91:2433-48. 2010
    ..Based on our results we propose two novel genera, Orthoturdivirus for TV1, and Paraturdivirus for TV2 and TV3, in the family Picornaviridae. The type of internal ribosomal entry site for TV1, TV2 and TV3 remains to be determined...
  62. pmc Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats
    Susanna K P Lau
    Department of Microbiology, Research Centre of Infection and Immunology, State Key Laboratory of Emerging Infectious Diseases, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong Special Administrative Region, China
    Proc Natl Acad Sci U S A 102:14040-5. 2005
    ..Neutralizing antibody to human SARS-CoV also was detected in bats with lower viral loads. Precautions should be exercised in the handling of these animals...
  63. ncbi request reprint Characterization of a novel insertion sequence, IS Bp1, in Burkholderia pseudomallei
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    Arch Microbiol 177:267-73. 2002
    ..Using several insertion sequences and a combination of insertion-sequence-based and non-insertion-sequence-based methods such as ribotyping will probably increase the discriminatory power of molecular typing in B. pseudomallei...
  64. pmc Ecoepidemiology and complete genome comparison of different strains of severe acute respiratory syndrome-related Rhinolophus bat coronavirus in China reveal bats as a reservoir for acute, self-limiting infection that allows recombination events
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, Research Centre of Infection and Immunology, Department of Microbiology, The University of Hong Kong, Hong Kong, Hong Kong
    J Virol 84:2808-19. 2010
    ..Such frequent recombination, coupled with rapid evolution especially in ORF7b/ORF8 region, in these animals may have accounted for the cross-species transmission and emergence of SARS...
  65. ncbi request reprint Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics
    Richard Y Kao
    Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Chem Biol 11:1293-9. 2004
    ....
  66. pmc Ecoepidemiology of Laribacter hongkongensis, a novel bacterium associated with gastroenteritis
    Jade L L Teng
    Department of Microbiology, University of Hong Kong, Hong Kong
    J Clin Microbiol 43:919-22. 2005
    ..Comparing the pulsed-field gel electrophoresis patterns of fish and patient isolates revealed that most patient isolates were clustered together, suggesting that some clones could be more virulent...
  67. pmc Human parainfluenza virus 4 outbreak and the role of diagnostic tests
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital
    J Clin Microbiol 43:4515-21. 2005
    ..To better define the epidemiology and clinical spectrum of disease of HPIV-4 infections, HPIV-4 should be included in the routine panels of respiratory virus detection on respiratory specimens...
  68. pmc Catabacter hongkongensis gen. nov., sp. nov., isolated from blood cultures of patients from Hong Kong and Canada
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, Hong Kong
    J Clin Microbiol 45:395-401. 2007
    ..hongkongensis. Further studies should be performed to ascertain the epidemiology and other disease associations of this bacterium...
  69. ncbi request reprint Anaerobic, non-sporulating, Gram-positive bacilli bacteraemia characterized by 16S rRNA gene sequencing
    Susanna K P Lau
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Med Microbiol 53:1247-53. 2004
    ..Further studies to look for specific virulence factors are warranted...
  70. ncbi request reprint Identification of influenza A nucleoprotein as an antiviral target
    Richard Y Kao
    Department of Microbiology, The University of Hong Kong, Hong Kong
    Nat Biotechnol 28:600-5. 2010
    ..Our results demonstrate that viral NP is a valid target for the development of small-molecule therapies...
  71. doi request reprint Leptin mediates the pathogenesis of severe 2009 pandemic influenza A(H1N1) infection associated with cytokine dysregulation in mice with diet-induced obesity
    Anna J X Zhang
    Carol Yu Centre for Infection and Division of Infectious Diseases, Department of Microbiology, University of Hong Kong, Queen Mary Hospital, Pokfulam Rd, Pokfulam, Hong Kong SAR, China
    J Infect Dis 207:1270-80. 2013
    ..The mechanism for severe lung injury in obese patients and the specific treatment strategy remain elusive...
  72. pmc Isolation and characterization of a novel Betacoronavirus subgroup A coronavirus, rabbit coronavirus HKU14, from domestic rabbits
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong
    J Virol 86:5481-96. 2012
    ..Antibody against RbCoV was detected in 20 (67%) of 30 rabbit sera tested by an N-protein-based Western blot assay, whereas neutralizing antibody was detected in 1 of these 20 rabbits...
  73. ncbi request reprint Complete genome sequence of bat coronavirus HKU2 from Chinese horseshoe bats revealed a much smaller spike gene with a different evolutionary lineage from the rest of the genome
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, Hong Kong
    Virology 367:428-39. 2007
    ..These suggest a common evolutionary origin in the spike protein of bat-CoV HKU2, bat-SARS-CoV, and SARS-CoV...
  74. pmc Natural occurrence and characterization of two internal ribosome entry site elements in a novel virus, canine picodicistrovirus, in the picornavirus-like superfamily
    Patrick C Y Woo
    State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong
    J Virol 86:2797-808. 2012
    ..Based on our results, we have proposed a novel species, canine picodicistrovirus (CPDV), to describe this novel member of the picornavirus-like superfamily, which could represent a novel family of viruses...
  75. pmc Discovery and genomic characterization of a novel ovine partetravirus and a new genotype of bovine partetravirus
    Herman Tse
    Department of Microbiology, The University of Hong Kong, Hong Kong, China
    PLoS ONE 6:e25619. 2011
    ..Results from the present study provide further support to the classification of partetraviruses as a separate genus in Parvovirinae...
  76. doi request reprint High diversity of polyketide synthase genes and the melanin biosynthesis gene cluster in Penicillium marneffei
    Patrick C Y Woo
    State Key Laboratory of Emerging Infectious Diseases, Hong Kong, China
    FEBS J 277:3750-8. 2010
    ..marneffei and 6 min for the alb1 knockdown mutant of P. marneffei, implying that the melanin-biosynthesis gene cluster contributed to virulence through decreased susceptibility to killing by hydrogen peroxide...
  77. ncbi request reprint D225G mutation in hemagglutinin of pandemic influenza H1N1 (2009) virus enhances virulence in mice
    Bojian Zheng
    Department of Microbiology, The University of Hong Kong, Pokfulam, China
    Exp Biol Med (Maywood) 235:981-8. 2010
    ..The only consistent mutation in the genomes of viral clones obtained from dying mice was D225G substitution...
  78. pmc Comparative host gene transcription by microarray analysis early after infection of the Huh7 cell line by severe acute respiratory syndrome coronavirus and human coronavirus 229E
    Bone S F Tang
    Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, Center of Infection and Immunology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China
    J Virol 79:6180-93. 2005
    ..These transcriptomal changes are compatible with the histological changes of pulmonary vasculitis and microvascular thrombosis in addition to the diffuse alveolar damage involving the pneumocytes...
  79. pmc Internal transcribed spacer region sequence heterogeneity in Rhizopus microsporus: implications for molecular diagnosis in clinical microbiology laboratories
    Patrick C Y Woo
    State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong
    J Clin Microbiol 48:208-14. 2010
    ..When thick bands and double peaks are observed during PCR sequencing of a gene target, such a strain should be sent to reference laboratories proficient in molecular technologies for further identification and/or genotyping...
  80. pmc Clinical and molecular epidemiology of human parainfluenza virus 4 infections in hong kong: subtype 4B as common as subtype 4A
    Susanna K P Lau
    Department of Microbiology, State Key Laboratory of Emerging Infectious Diseases, Research Centre of Infection and Immunology, The University of Hong Kong, Hong Kong
    J Clin Microbiol 47:1549-52. 2009
    ..Patients with HPIV4 infection were mainly young children and immunocompromised adults. In contrast to the reported predominance of HPIV4A infection, molecular subtyping revealed that 15 (44%) cases were caused by HPIV4B...
  81. pmc Development of a multi-locus sequence typing scheme for Laribacter hongkongensis, a novel bacterium associated with freshwater fish-borne gastroenteritis and traveler's diarrhea
    Patrick C Y Woo
    State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, PR China
    BMC Microbiol 9:21. 2009
    ..hongkongensis. In this study, a multilocus sequence typing (MLST) system was developed for L. hongkongensis. The system was used to characterize 146 L. hongkongensis isolates, including 39 from humans and 107 from fish...
  82. pmc Analysis of a viridans group strain reveals a case of bacteremia due to lancefield group G alpha-hemolytic Streptococcus dysgalactiae subsp equisimilis in a patient with pyomyositis and reactive arthritis
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, Hong Kong
    J Clin Microbiol 41:613-8. 2003
    ..dysgalactiae subsp. equisimilis or a novel type of S. dysgalactiae. The present case showed that group G alpha-hemolytic S. dysgalactiae subsp. equisimilis can be associated with serious invasive infection and poststreptococcal sequelae...
  83. pmc Complete genome analysis of three novel picornaviruses from diverse bat species
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Virol 85:8819-28. 2011
    ..This report describes the discovery and complete genome analysis of three picornaviruses in bats, and their presence in diverse bat genera/species suggests the ability to cross the species barrier...
  84. pmc Clinical spectrum of exophiala infections and a novel Exophiala species, Exophiala hongkongensis
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, Hong Kong, China
    J Clin Microbiol 51:260-7. 2013
    ..We propose the new species Exophiala hongkongensis to describe this novel fungus...
  85. pmc Automated pangenomic analysis in target selection for PCR detection and identification of bacteria by use of ssGeneFinder Webserver and its application to Salmonella enterica serovar Typhi
    Chi Chun Ho
    Department of Microbiology, The University of Hong Kong, Hong Kong, China
    J Clin Microbiol 50:1905-11. 2012
    ..Typhi. These and other validated targets should be applicable to the identification and direct PCR detection of bacterial pathogens from uncultured, mixed, and environmental samples...
  86. pmc Identification of a novel feline picornavirus from the domestic cat
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, Hong Kong
    J Virol 86:395-405. 2012
    ..Further studies are important to understand the pathogenicity, epidemiology, and genetic evolution of FePV in these common pet animals...
  87. pmc Clinical features and complete genome characterization of a distinct human rhinovirus (HRV) genetic cluster, probably representing a previously undetected HRV species, HRV-C, associated with acute respiratory illness in children
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, University Pathology Building, Queen Mary Hospital, Hong Kong
    J Clin Microbiol 45:3655-64. 2007
    ..A newly identified HRV species, HRV-C, is circulating worldwide and is an important cause of febrile wheeze and asthmatic exacerbations in children requiring hospitalization...
  88. doi request reprint A regulatory polymorphism in interferon-gamma receptor 1 promoter is associated with the susceptibility to chronic hepatitis B virus infection
    Jie Zhou
    Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong, Hong Kong SAR, China
    Immunogenetics 61:423-30. 2009
    ..We conclude that a functional -56C/T SNP in IFNGR1 promoter is associated with the clinical outcome of HBV infection in this Chinese population...
  89. ncbi request reprint Construction of an inducible expression shuttle vector for Laribacter hongkongensis, a novel bacterium associated with gastroenteritis
    Patrick C Y Woo
    Department of Microbiology, Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital Compound, Pokfulam Road, Hong Kong
    FEMS Microbiol Lett 252:57-65. 2005
    ..This inducible expression system was able to express two commonly used reporter genes, the green fluorescent protein gene and the glutathione S-transferase gene, efficiently in E. coli and L. hongkongensis...
  90. doi request reprint Is the discovery of the novel human betacoronavirus 2c EMC/2012 (HCoV-EMC) the beginning of another SARS-like pandemic?
    Jasper F W Chan
    Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    J Infect 65:477-89. 2012
    ..Despite the apparently low transmissibility of the virus at this stage, research preparedness against another SARS-like pandemic is an important precautionary strategy...
  91. pmc Characterization of a Tsukamurella pseudo-outbreak by phenotypic tests, 16S rRNA sequencing, pulsed-field gel electrophoresis, and metabolic footprinting
    Kelvin K W To
    State Key Laboratory for Emerging Infectious Diseases, The University of Hong Kong, Hong Kong, Hong Kong
    J Clin Microbiol 51:334-8. 2013
    ..This report highlights that early recognition of pseudo-outbreaks is important in preventing unnecessary and incorrect treatment of patients...
  92. pmc Identification of a novel bat papillomavirus by metagenomics
    Herman Tse
    State Key Laboratory of Emerging Infectious Diseases, Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Pok Fu Lam, Hong Kong Island, Hong Kong
    PLoS ONE 7:e43986. 2012
    ..We propose MscPV1 as the first member of the novel Dyolambda-papillomavirus genus...
  93. ncbi request reprint Molecular epidemiology and household transmission of community-associated methicillin-resistant Staphylococcus aureus in Hong Kong
    Pak Leung Ho
    Department of Microbiology and Centre of Infection, University of Hong Kong, Hong Kong SAR, PR China
    Diagn Microbiol Infect Dis 57:145-51. 2007
    ..In conclusion, CA-MRSA has a propensity to spread within families. Our findings showed that CA-MRSA strains in Hong Kong have diverse genetic backgrounds...
  94. ncbi request reprint Alkanindiges hongkongensis sp. nov. A novel Alkanindiges species isolated from a patient with parotid abscess
    Patrick C Y Woo
    Department of Microbiology, The University of Hong Kong, University Pathology Building, Queen Mary Hospital Compound, Pokfulam Road, Hong Kong
    Syst Appl Microbiol 28:316-22. 2005
    ....
  95. pmc MBEToolbox: a MATLAB toolbox for sequence data analysis in molecular biology and evolution
    James J Cai
    Department of Microbiology, University of Hong Kong, Pokfulam, Hong Kong, China
    BMC Bioinformatics 6:64. 2005
    ..However, few functions are freely available in MATLAB to perform the sequence data analyses specifically required for molecular biology and evolution...
  96. pmc Wild type and mutant 2009 pandemic influenza A (H1N1) viruses cause more severe disease and higher mortality in pregnant BALB/c mice
    Kwok Hung Chan
    Department of Microbiology, University of Hong Kong, Hong Kong Special Administrative Region, China
    PLoS ONE 5:e13757. 2010
    ..Pregnant women infected by the pandemic influenza A (H1N1) 2009 virus had more severe disease and higher mortality but its pathogenesis is still unclear...
  97. pmc Priming with rAAV encoding RBD of SARS-CoV S protein and boosting with RBD-specific peptides for T cell epitopes elevated humoral and cellular immune responses against SARS-CoV infection
    Lanying Du
    Department of Microbiology, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Vaccine 26:1644-51. 2008
    ....
  98. doi request reprint Concurrent comparison of epidemiology, clinical presentation and outcome between adult patients suffering from the pandemic influenza A (H1N1) 2009 virus and the seasonal influenza A virus infection
    Kelvin K W To
    Carol Yu Centre for Infection, The University of Hong Kong, China
    Postgrad Med J 86:515-21. 2010
    ..The demographics, clinical features and outcome of patients with pandemic influenza A (H1N1) 2009 infection were compared with a concurrent cohort of patients with seasonal influenza A infection...
  99. doi request reprint Effect of clinical and virological parameters on the level of neutralizing antibody against pandemic influenza A virus H1N1 2009
    Ivan F N Hung
    Department of Microbiology, The University of Hong Kong, Hong Kong
    Clin Infect Dis 51:274-9. 2010
    ..The relative lack of background neutralizing antibody against this novel virus provides a unique opportunity for understanding this issue...
  100. doi request reprint Viral load in patients infected with pandemic H1N1 2009 influenza A virus
    Kelvin K W To
    Department of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China
    J Med Virol 82:1-7. 2010
    ..Younger age was associated with prolonged shedding in the respiratory tract and higher viral load in the stool. Data from this quantitative analysis of viral shedding may have implications for formulating infection control measures...
  101. pmc First report of Gordonibacter pamelaeae bacteremia
    Patrick C Y Woo
    State Key Laboratory of Emerging Infectious Diseases, The University of Hong Kong, Hong Kong
    J Clin Microbiol 48:319-22. 2010
    ..The bacterium was a nonsporulating, anaerobic, gram-positive, nonmotile, coccobacillus that was catalase, arginine dihydrolase, and arginine acrylamidase positive. The gastrointestinal tract is probably its reservoir...