Research Topics
Species | Virginia C N WongSummaryAffiliation: University of Hong Kong Country: China Publications
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Detail Information
Publications
Acupuncture for acute management and rehabilitation of traumatic brain injuryVirginia Wong
Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
Cochrane Database Syst Rev 3:CD007700. 2013..A number of studies conducted and published in China have suggested that acupuncture may be beneficial in the acute treatment and rehabilitation of TBI...
Acupuncture for hypoxic ischemic encephalopathy in neonatesVirginia Wong
Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
Cochrane Database Syst Rev 1:CD007968. 2013..Hypoxic ischemic encephalopathy (HIE) in the neonate is associated with high mortality and morbidity. Effective treatment options are limited and therefore alternative therapies such as acupuncture are increasingly used...
Acupuncture for acute management and rehabilitation of traumatic brain injuryVirginia Wong
Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
Cochrane Database Syst Rev 12:CD007700. 2012..A number of studies conducted and published in China have suggested that acupuncture may be beneficial in the acute treatment and rehabilitation of TBI...
Accupouncture for acute management and rehabilitation of traumatic brain injuryV Wong
Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, Queen Mary Hospital, SAR, China
Eur J Phys Rehabil Med 48:71-86. 2012....
Pilot study of positron emission tomography (PET) brain glucose metabolism to assess the efficacy of tongue and body acupuncture in cerebral palsyVirginia C N Wong
Department of Pediatrics and Adolescent Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong ROC
J Child Neurol 21:456-62. 2006..A larger-scale study for different degrees of severity of cerebral palsy and an impairment model should be undertaken to correlate clinical with neurometabolic change...
A modified screening tool for autism (Checklist for Autism in Toddlers [CHAT-23]) for Chinese childrenVirginia Wong
Department of Paediatrics and Adolescent Medicine, University of Hong Kong, Hong Kong
Pediatrics 114:e166-76. 2004..Joint attention was addressed in the original CHAT, whereas the other areas were addressed only in the M-CHAT. To date, there has been no study of the application of either the original CHAT or the M-CHAT for Chinese populations...
Spinal muscular atrophy: survival pattern and functional statusBrian H Y Chung
Division of Neurodevelopmental Paediatrics, Department of Paediatrics and Adolescent Medicine, University of Hong Kong, Hong Kong, China
Pediatrics 114:e548-53. 2004..The objective of this study was to assess the survival pattern, ambulatory status, and functional status of children with SMA...
Cerebral palsy: correlation of risk factors and functional performance using the Functional Independence Measure for Children (WeeFIM)Virginia Wong
Division of Neurodevelopmental Paediatrics, Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong
J Child Neurol 19:887-93. 2004..007) analyses. The functional status of children with cerebral palsy depends on the severity and the presence of epilepsy. Despite impairment, we found that most children with cerebral palsy could achieve functional independence...
Correlation of Functional Independence Measure for Children (WeeFIM) with developmental language tests in children with developmental delayVirginia Wong
Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China
J Child Neurol 20:613-6. 2005....
Stiff child syndrome with mutation of DYT1 geneVirginia C N Wong
Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
Neurology 65:1465-6. 2005..Autoantibodies to glutamic acid decarboxylase (anti-GAD) were absent. His asymptomatic mother had a DYT1 mutation. His asymptomatic sister has diabetes mellitus and antibodies to glutamic acid decarboxylase but no DYT1 mutation...
Tuberous sclerosis complex: correlation of magnetic resonance imaging (MRI) findings with comorbiditiesVirginia Wong
Department of Paediatrics, The University of Hong Kong, China
J Child Neurol 21:99-105. 2006....
Pilot study of efficacy of tongue and body acupuncture in children with visual impairmentVirginia C N Wong
Department of Pediatrics and Adolescent Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong ROC
J Child Neurol 21:463-73. 2006..As children with chronic visual impairment also showed some visual recovery, more studies should be done to assess the full potential of acupuncture as an adjunct to Western medicine in neuroplasticity...
Short- and long-term outcome of severe neonatal nonhemolytic hyperbilirubinemiaVirginia Wong
Division of Neurodevelopmental Paediatrics, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong
J Child Neurol 21:309-15. 2006....
Study of the relationship between tuberous sclerosis complex and autistic disorderVirginia Wong
Division of Neurodevelopmental Paediatrics, Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China
J Child Neurol 21:199-204. 2006....
Occipital deep white matter hyperintensities in autism spectrum disorderVirginia Wong
Division of Neurodevelopmental Paediatrics, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
Pediatr Int 49:513-5. 2007
Functional Independence Measure (WeeFIM) for Chinese children: Hong Kong CohortVirginia Wong
Department of Paediatrics, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
Pediatrics 109:E36. 2002..During the task, there is no concern about safety or taking an inordinate amount of time. Level 6 reflects modified independence and includes use of an assistive device or not completing the task in a timely or safe manner...
Study of seizure and epilepsy in Chinese children in Hong Kong: period prevalence and patternsVirginia Wong
Division of Neurodevelopmental Pediatrics, Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China
J Child Neurol 19:19-25. 2004..5 per 1000 children aged < 19 years. The estimated period prevalence rate of children and adolescents with epilepsy in our children is 4.5 per 1000 children...
Rett syndrome: prevalence among Chinese and a comparison of MECP2 mutations of classic Rett syndrome with other neurodevelopmental disordersVirginia C N Wong
Department of Pediatrics and Adolescent Medicine, The University of Hong Kong
J Child Neurol 22:1397-400. 2007..In the early stage of developmental arrest before developmental regression, MECP2 screening might be useful for girls with unexplained epileptic encephalopathy before full-blown classic Rett syndrome is evident...
Evidence-based approach of the use of Botulinum toxin type A (BTX) in cerebral palsyVirginia Wong
Division of Neurodevelopmental Paediatrics, Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, P R China
Pediatr Rehabil 6:85-96. 2003..More multi-centre clinical trials with standardized protocols are needed before widespread recommendation of the use of BTX in treating spasticity in CP can be made...
Molecular genetic study of a childhood form of spinal muscular atrophyV Wong
Department of Paediatrics, Queen Mary Hospital, Faculty of Medicine, The University of Hong Kong
J Child Neurol 16:291-4. 2001..Thus, the role of the NAIP gene needs to be specifically defined in spinal muscular atrophy. In a suspected case of spinal muscular atrophy, deletion of the SMNt gene is a useful laboratory marker for confirmation of the diagnosis...
West syndrome--The University of Hong Kong experience (1970-2000)V Wong
Department of Paediatrics, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
Brain Dev 23:609-15. 2001..To study the clinical pattern of West syndrome (WS) in a university based hospital...
Open-label study of botulinum toxin for upper limb spasticity in cerebral palsyVirginia Wong
Department of Pediatrics, The University of Hong Kong, Queen Mary Hospital, People s Republic of China
J Child Neurol 17:138-42. 2002..Motivated families should be selected with a specific target of using botulinum toxin as an adjunct in a habilitation program...
Acute gastroenteritis-related encephalopathyV Wong
Department of Paediatrics, The University of Hong Kong, Queen Mary Hospital
J Child Neurol 16:906-10. 2001..The underlying mechanism for provoking seizure is unknown. One should be reassured of a good outcome in the majority of children with recurrent episodes of afebrile/febrile seizures during an episode of acute gastroenteritis...
Mutation of gene in spinal muscular atrophy respiratory distress type IVirginia C N Wong
Division of Neurodevelopmental Paediatrics, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong
Pediatr Neurol 34:474-7. 2006....
Epidemiological study of autism spectrum disorder in ChinaVirginia C N Wong
Division of Child Neurology Developmental Paediatrics Neurohabilitation, Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, China
J Child Neurol 23:67-72. 2008..58:1. This is the first reported epidemiologic study of autism spectrum disorder in Chinese children. The incidence rate is similar to those reported in Australia and North America and is lower than Europeans...
Functional Independence Measure for Children: a comparison of Chinese and Japanese childrenSheila S N Wong
Department of Paediatrics and Adolescent Medicine, United Christian Hospital, Hong Kong
Neurorehabil Neural Repair 21:91-6. 2007..In 2001 to 2002, the authors created a normative Chinese WeeFIM profile and compared this with the American one. In this study, they aimed to compare their Chinese normative data with the Japanese one...
Magnetic resonance spectroscopy and analysis of MECP2 in Rett syndromePek Lan Khong
Department of Diagnostic Radiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong
Pediatr Neurol 26:205-9. 2002..Our preliminary results suggest that reduction in N-acetylaspartate/total creatine ratio may not be related to the MECP2 mutation...
Vanishing white matter disease: the first reported chinese patientSheila S N Wong
Department of Paediatrics and Adolescent Medicine, United Christian Hospital, Kowloon, Hong Kong SAR, China
J Child Neurol 23:710-4. 2008..We describe the first Chinese patient with typical clinical and radiological features genetically confirmed to have vanishing white matter disease for a mutation in EIF2B4, followed by a brief review of the disease...
Expanding phenotype and clinical analysis of tyrosine hydroxylase deficiencyWai Lan Yeung
Department of Paediatrics, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China
J Child Neurol 26:179-87. 2011..Treatment response for mild-type patients is universally good even with a treatment delay of 10 years after onset of neurological symptoms...
Neurodevelopmental outcome of severe neonatal hemolytic hyperbilirubinemiaWen-Xiong Chen
Division of Neurodevelopmental Pediatrics, Department of Pediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong ROC
J Child Neurol 21:474-9. 2006..The prognosis of neonatal hemolytic hyperbilirubinemia in our Chinese cohort is excellent, possibly owing to an aggressive early-intervention approach...
Brief report: emerging services for children with autism spectrum disorders in Hong Kong (1960-2004)Virginia C N Wong
Division of Child Neurology Developmental Paediatrics Neurohabilitation, Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China
J Autism Dev Disord 38:383-9. 2008..The university-based Autism Research Program at the University of Hong Kong serves as an example of an integrated center for research, teaching, and training in autism. The period from 1960 to 2004 is reviewed...
The human secretin gene in children with autistic spectrum disorder: screening for polymorphisms and mutationsSamuel S M Ng
Institute of Molecular Biology, The University of Hong Kong, Hong Kong
J Child Neurol 20:701-4. 2005..We did not find evidence of a relationship between human secretin gene mutation and autism...
Randomized controlled trial of electro-acupuncture for autism spectrum disorderVirginia C N Wong
Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
Altern Med Rev 15:136-46. 2010..To study the efficacy, safety, and compliance of short-term electro-acupuncture for children with autism spectrum disorder (ASD)...
Electroacupuncture for children with autism spectrum disorder: pilot study of 2 casesWen Xiong Chen
Division of Child Neurology Developmental Paediatrics Neurohabilitation, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
J Altern Complement Med 14:1057-65. 2008..The objective of this study was to observe for efficacy, safety, and compliance of electroacupuncture for autism spectrum disorder (ASD)...
The evaluation of Wallerian degeneration in chronic paediatric middle cerebral artery infarction using diffusion tensor MR imagingPek Lan Khong
Department of Diagnostic Radiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
Cerebrovasc Dis 18:240-7. 2004....
Subacute sclerosing panencephalitis in children: prevalence in South ChinaPatrick Ip
Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
Pediatr Neurol 31:46-51. 2004..Active surveillance of subacute sclerosing panencephalitis for those with measles infection during the 1988 outbreak is necessary to conduct multicenter drug trials for this devastating disease...
DNA diagnosis of FRAXA and FRAXE in Chinese children with neurodevelopmental disorders and fragile X syndromeS Y Chan
Department of Paediatrics, The University of Hong Kong, Queen Mary Hospital, Hong Kong
Clin Genet 53:179-83. 1998....
MRI of neonatal encephalopathyP L Khong
Department of Diagnostic Radiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong, People s Republic of China
Clin Radiol 58:833-44. 2003..The applications of advanced MRI techniques, such as diffusion-weighted imaging and magnetic resonance spectroscopy are emphasized...
Randomized controlled trial for early intervention for autism: a pilot study of the Autism 1-2-3 ProjectVirginia C N Wong
Division of Child Neurology Developmental Paediatrics Neurohabilitation, Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Pokfulam Road, Hong Kong, China
J Autism Dev Disord 40:677-88. 2010..This intervention can serve as short-term training on communication and social interaction for children with autism, and reduce the stress of their parents during the long waiting time for public health services...
Acute fulminant subacute sclerosing panencephalitis with absent measles and PCR studies in cerebrospinal fluidBrian H Y Chung
Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, China
Pediatr Neurol 31:222-4. 2004..There were no typical periodic complexes in serial electroencephalographic monitoring; cerebrospinal fluid measles antibody titer was negative.The diagnosis was made by molecular and histologic examination of open brain biopsy tissue...
MR imaging of spinal tumors in children with neurofibromatosis 1Pek-Lan Khong
Department of Diagnostic Radiology, Rm. 406, Block K, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong
AJR Am J Roentgenol 180:413-7. 2003....
Anti-NMDA receptor encephalitis with atypical brain changes on MRISophelia H S Chan
Division of Child Neurology Developmental Paediatrics Neurohabilitation, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China
Pediatr Neurol 43:274-8. 2010..Persistent lesions in the white matter and pons were observed in magnetic resonance imaging of the brain, findings that have not been described previously in N-methyl-D-aspartate receptor antibody encephalitis...
Value of clinical assessment in the diagnostic evaluation of Global Developmental Delay (GDD) using a Likelihood Ratio ModelVirginia C N Wong
Division of Child Neurology Developmental Paediatrics Neurohabilitation, Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong
Brain Dev 33:548-57. 2011..A selective approach is recommended for investigating children with GDD. Our objective is to identify clinical markers to improve the diagnostic yield of evaluation of children with GDD...
Childhood acute disseminated encephalomyelitis: the role of brain and spinal cord MRIPek Lan Khong
Department of Diagnostic Radiology, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong
Pediatr Radiol 32:59-66. 2002..It is recognised that the clinical and radiological spectrum of childhood acute disseminated encephalomyelitis (ADEM) is wide...
Effect of acupuncture in a patient with 7-year-history of Bell's palsyChau Lai Wong
Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong
J Altern Complement Med 14:847-53. 2008..To demonstrate the effect of acupuncture in a child with chronic Bell's palsy of 7 years duration...
Neuromuscular junction acetylcholinesterase deficiency responsive to albuterolSophelia H S Chan
Division of Child Neurology, Developmental Paediatrics, and Neurohabilitation, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong Special Administrative Region
Pediatr Neurol 47:137-40. 2012..Further studies are needed of the efficacy of albuterol in different types of congenital myasthenic syndrome and the physiologic basis of its beneficial effects...
Efficacy and safety of levetiracetam as adjunctive therapy in adult patients with uncontrolled partial epilepsy: the Asia SKATE II StudyPatrick Kwan
The Chinese University of Hong Kong, Hong Kong, China
Epilepsy Behav 18:100-5. 2010..4%, and 17.7% became seizure free during the treatment period. Levetiracetam was well tolerated and efficacious as adjunctive therapy for partial epilepsy in clinical practice among Asian populations...
Traditional Chinese medicine (tongue acupuncture) in children with drooling problemsV Wong
Division of Neurodevelopmental Paediatrics, University of Hong Kong, China
Pediatr Neurol 25:47-54. 2001....
Attention-deficit hyperactivity disorder and blood mercury level: a case-control study in chinese childrenD K L Cheuk
Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, P. R. China
Neuropediatrics 37:234-40. 2006..69 times (95 % CI 2.57 - 36.5) higher risk of having ADHD after adjustment for confounding variables. CONCLUSION: High blood mercury level was associated with ADHD. Whether the relationship is causal requires further studies...
Acute viral encephalitis in childrenV Wong
Department of Paediatrics, University of Hong Kong, Queen Mary Hospital
Aust Paediatr J 23:339-42. 1987..The best predictors to unfavourable outcome were the rapid rate of deterioration in conscious level after admission and the age of the patients...
An evaluation of the psychometric properties of the Smoking Self-Efficacy Questionnaire (SEQ-12) among Chinese cardiac patients who smokeDoris Y P Leung
Department of Nursing Studies, Li Ka Shing Faculty of Nursing, The University of Hong Kong, 4 F William MW Mong Block, Pokfulam, Hong Kong
Nicotine Tob Res 10:1311-8. 2008..The SEQ-12 can be used to assess smokers' self-efficacy so that appropriate smoking cessation interventions can be provided...
Cultivating psychological well-being in Hong Kong's future doctorsJ G W S Wong
Department of Psychiatry, The Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
Med Teach 27:715-9. 2005..The findings in this study help to ensure that the services provided will be relevant, accessible and acceptable to the students...
A multistep mutation mechanism drives the evolution of the CAG repeat at MJD/SCA3 locusSandra Martins
IPATIMUP Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal
Eur J Hum Genet 14:932-40. 2006....
T2-weighted hyperintensities (unidentified bright objects) in children with neurofibromatosis 1: their impact on cognitive functionWinnie H S Goh
The Duchess of Kent Children s Habilitation Institute, Hong Kong
J Child Neurol 19:853-8. 2004..55; P = .005). Unidentified bright objects in the thalamus, globus pallidus, and middle cerebellar peduncles and the laterality of the lesions had an impact on cognitive function...
Neurologic complications in children hospitalized with influenza: comparison between USA and Hong KongBrian H Y Chung
J Pediatr 151:e17-8; author reply e18-9. 2007
