Elly S W Ngan
Affiliation: University of Hong Kong
Ngan E, Lee K, Yeung W, Ngan H, Ng E, Ho P. Endocrine gland-derived vascular endothelial growth factor is expressed in human peri-implantation endometrium, but not in endometrial carcinoma. Endocrinology. 2006;147:88-95 pubmed
..It may imply that EG-VEGF may only play a role in vascular function of peri-implantation endometrium, but is unlikely to be associated with the etiology of endometrial cancer development. ..
Ngan E, Sit F, Lee K, Miao X, Yuan Z, Wang W, et al
. Implications of endocrine gland-derived vascular endothelial growth factor/prokineticin-1 signaling in human neuroblastoma progression. Clin Cancer Res. 2007;13:868-75 pubmed
..Our study has shown for the first time that aberrant EG-VEGF/Prok-1 signaling favors neuroblastoma progression and could be a potential target for future neuroblastoma treatment. ..
Ngan E, Lee K, Sit F, Poon H, Chan J, Sham M, et al
. Prokineticin-1 modulates proliferation and differentiation of enteric neural crest cells. Biochim Biophys Acta. 2007;1773:536-45 pubmed
..Taken together, it is the first report demonstrating that Prok-1 acts as a gut mucosa/mesenchyme-derived factor and maintains proliferation and differentiation of enteric NCCs. ..
Ngan E, Shum C, Poon H, Sham M, Garcia Barcelo M, Lui V, et al
. Prokineticin-1 (Prok-1) works coordinately with glial cell line-derived neurotrophic factor (GDNF) to mediate proliferation and differentiation of enteric neural crest cells. Biochim Biophys Acta. 2008;1783:467-78 pubmed
..Taken together, these findings provide evidence that Prok-1 crosstalks with GDNF/Ret signaling and probably provides an additional layer of signaling refinement to maintain proliferation and differentiation of enteric NCCs. ..