Mo Yin Mok

Summary

Affiliation: University of Hong Kong
Country: China

Publications

  1. pmc Comparison of performance of the Assessment of SpondyloArthritis International Society, the European Spondyloarthropathy Study Group and the modified New York criteria in a cohort of Chinese patients with spondyloarthritis
    Ho Yin Chung
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, SAR China
    Clin Rheumatol 30:947-53. 2011
  2. doi request reprint The immunological basis of B-cell therapy in systemic lupus erythematosus
    Mo Yin Mok
    Division of Rheumatology and Immunology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong
    Int J Rheum Dis 13:3-11. 2010
  3. doi request reprint Serum levels of IL-33 and soluble ST2 and their association with disease activity in systemic lupus erythematosus
    Mo Yin Mok
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Rheumatology (Oxford) 49:520-7. 2010
  4. doi request reprint The relation of interleukin 17 (IL-17) and IL-23 to Th1/Th2 cytokines and disease activity in systemic lupus erythematosus
    Mo Yin Mok
    Division of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, Hong Kong
    J Rheumatol 37:2046-52. 2010
  5. doi request reprint Do Asian patients have worse lupus?
    M Y Mok
    Division of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong
    Lupus 19:1384-90. 2010
  6. ncbi request reprint Low circulating level of CD133+KDR+cells in patients with systemic sclerosis
    M Y Mok
    Division of Rheumatology and Immunology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Clin Exp Rheumatol 28:S19-25. 2010
  7. doi request reprint Systemic sclerosis is an independent risk factor for increased coronary artery calcium deposition
    Mo Yin Mok
    Queen Mary Hospital and University of Hong Kong, Hong Kong
    Arthritis Rheum 63:1387-95. 2011
  8. doi request reprint Coronary atherosclerosis using computed tomography coronary angiography in patients with systemic sclerosis
    M Y Mok
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, PR China
    Scand J Rheumatol 38:381-5. 2009
  9. doi request reprint ELF1 is associated with systemic lupus erythematosus in Asian populations
    Jing Yang
    Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong, China
    Hum Mol Genet 20:601-7. 2011
  10. ncbi request reprint Pattern of arterial calcification in patients with systemic lupus erythematosus
    Kai Hang Yiu
    Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong
    J Rheumatol 36:2212-7. 2009

Collaborators

Detail Information

Publications33

  1. pmc Comparison of performance of the Assessment of SpondyloArthritis International Society, the European Spondyloarthropathy Study Group and the modified New York criteria in a cohort of Chinese patients with spondyloarthritis
    Ho Yin Chung
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, SAR China
    Clin Rheumatol 30:947-53. 2011
    ..Compared with established AS patients recognized by MNY criteria, patients fulfilling USpA defined by ESSG or ASAS criteria had earlier disease, as active disease and less irreversible functional deficit...
  2. doi request reprint The immunological basis of B-cell therapy in systemic lupus erythematosus
    Mo Yin Mok
    Division of Rheumatology and Immunology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong
    Int J Rheum Dis 13:3-11. 2010
    ..This article provides an overview on normal B-cell physiology and abnormal B-cell biology in SLE that form the immunological basis of B-cell-targeted therapy in the treatment of these patients with refractory diseases...
  3. doi request reprint Serum levels of IL-33 and soluble ST2 and their association with disease activity in systemic lupus erythematosus
    Mo Yin Mok
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Rheumatology (Oxford) 49:520-7. 2010
    ..This study aims to measure the serum levels of soluble ST2 (sST2) and IL-33 in patients with SLE and to examine their association with disease activity...
  4. doi request reprint The relation of interleukin 17 (IL-17) and IL-23 to Th1/Th2 cytokines and disease activity in systemic lupus erythematosus
    Mo Yin Mok
    Division of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, Hong Kong
    J Rheumatol 37:2046-52. 2010
    ..We examined the relation between serum levels of Th17 (IL-17, IL-23), Th1 (IL-12, interferon-γ), Th2 (IL-10, IL-6, IL-4) cytokines and disease activity in patients with SLE...
  5. doi request reprint Do Asian patients have worse lupus?
    M Y Mok
    Division of Rheumatology and Clinical Immunology, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong
    Lupus 19:1384-90. 2010
    ..Poverty, education level, cultural and behavioural factors are confounders to ethnicity in determining clinical outcome of systemic lupus erythematosus...
  6. ncbi request reprint Low circulating level of CD133+KDR+cells in patients with systemic sclerosis
    M Y Mok
    Division of Rheumatology and Immunology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Clin Exp Rheumatol 28:S19-25. 2010
    ..Results of previous studies on the level of circulating endothelial progenitor cells (EPCs), which are involved in vascular repair, in scleroderma (SSc) patients have been controversial...
  7. doi request reprint Systemic sclerosis is an independent risk factor for increased coronary artery calcium deposition
    Mo Yin Mok
    Queen Mary Hospital and University of Hong Kong, Hong Kong
    Arthritis Rheum 63:1387-95. 2011
    ..This study was undertaken to examine the relationship between coronary atherosclerosis, as assessed by the coronary artery calcium score (CACS), and conventional cardiovascular and disease-specific risk factors in SSc patients...
  8. doi request reprint Coronary atherosclerosis using computed tomography coronary angiography in patients with systemic sclerosis
    M Y Mok
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, PR China
    Scand J Rheumatol 38:381-5. 2009
    ..Impaired coronary artery reserve has previously been demonstrated in patients with systemic sclerosis (SSc). Both micro- and macrovascular factors are probably contributory to the underlying pathogenesis...
  9. doi request reprint ELF1 is associated with systemic lupus erythematosus in Asian populations
    Jing Yang
    Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong, China
    Hum Mol Genet 20:601-7. 2011
    ....
  10. ncbi request reprint Pattern of arterial calcification in patients with systemic lupus erythematosus
    Kai Hang Yiu
    Cardiology Division, Department of Medicine, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong
    J Rheumatol 36:2212-7. 2009
    ..Multidetector computed tomography (MDCT) measured arterial calcium score (CS) reflecting underlying atherosclerosis and is closely associated with cardiovascular events...
  11. doi request reprint Role of circulating endothelial progenitor cells in patients with rheumatoid arthritis with coronary calcification
    Kai Hang Yiu
    Cardiology Division, Department of Medicine, The University of Hong Kong, Hong Kong
    J Rheumatol 37:529-35. 2010
    ..Patients with rheumatoid arthritis (RA) are prone to premature atherosclerosis. We hypothesize that depletion of circulating endothelial progenitor cells (EPC) related to RA can contribute to the development of atherosclerosis...
  12. doi request reprint The clinical course of polymyalgia rheumatica in Chinese
    Wai Ling Li
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pok Fu Lam, Hong Kong, China
    Clin Rheumatol 29:199-203. 2010
    ..Chinese patients with PMR have modestly different clinical profile compared to the Caucasian counterpart. RF and anti-CCP antibodies were more likely to be present in those who subsequently developed into RA...
  13. pmc Abnormalities in circulating plasmacytoid dendritic cells in patients with systemic lupus erythematosus
    Ou Jin
    Department of Medicine, The University of Hong Kong, Hong Kong, People s Republic of China
    Arthritis Res Ther 12:R137. 2010
    ..However, the functional characteristics of directly isolated peripheral circulating blood pDCs in SLE have not been evaluated previously...
  14. pmc ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai
    Wanling Yang
    Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong
    Hum Mol Genet 18:2063-70. 2009
    ..Therefore, despite the low-allele frequencies of the risk alleles of the gene in our two Asian populations, ITGAM was confirmed to be a risk factor related to disease susceptibility and probably severe manifestations of SLE...
  15. pmc Meta-analysis followed by replication identifies loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as associated with systemic lupus erythematosus in Asians
    Wanling Yang
    Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong
    Am J Hum Genet 92:41-51. 2013
    ..For the region involving TET3 and that involving CDKN1B, multiple independent SNPs were identified, highlighting a phenomenon that might partially explain the missing heritability of complex diseases...
  16. pmc Genome-wide association study in Asian populations identifies variants in ETS1 and WDFY4 associated with systemic lupus erythematosus
    Wanling Yang
    Department of Paediatrics and Adolescent Medicine, LKS Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong
    PLoS Genet 6:e1000841. 2010
    ..These new genetic findings may help us to gain a better understanding of the disease and the functions of the genes involved...
  17. ncbi request reprint Tuberculosis in systemic lupus erythematosus in an endemic area and the role of isoniazid prophylaxis during corticosteroid therapy
    Mo Yin Mok
    Department of Medicine, The University of Hong Kong, Hong Kong
    J Rheumatol 32:609-15. 2005
    ..We examined the usefulness of INAH in the prevention of recurrences of TB in patients with SLE receiving high dose corticosteroid therapy...
  18. doi request reprint Relationship between cardiac valvular and arterial calcification in patients with rheumatoid arthritis and systemic lupus erythematosus
    Kai Hang Yiu
    Cardiology Division, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    J Rheumatol 38:621-7. 2011
    ..We investigated the prevalence of valvular calcification in patients with RA and SLE and its relationship with arterial atherosclerotic calcification...
  19. ncbi request reprint Serum nitric oxide metabolites and disease activity in patients with systemic sclerosis
    Mo Yin Mok
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, Hong Kong
    Clin Rheumatol 27:315-22. 2008
    ..004 by trend). Serum NO(x) in SSc patients were elevated compared to healthy controls. Serum NO(x) level was determined by multiple factors including age, prednisolone use, and elevated PAP...
  20. ncbi request reprint Long-term study of mycophenolate mofetil as continuous induction and maintenance treatment for diffuse proliferative lupus nephritis
    Tak Mao Chan
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, New Clinical Building, Room 303, Pokfulam Road, Hong Kong
    J Am Soc Nephrol 16:1076-84. 2005
    ..062 by survival analysis). It is concluded that MMF and prednisolone constitute an effective continuous induction-maintenance treatment for DPLN in Chinese patients...
  21. doi request reprint Relationship between autoantibody clustering and clinical subsets in SLE: cluster and association analyses in Hong Kong Chinese
    Philip Hei Li
    Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    Rheumatology (Oxford) 52:337-45. 2013
    ..This study aims to identify the existence of, and relationship between autoantibody clusters and clinical subsets in Chinese SLE patients...
  22. ncbi request reprint Prognostic role of coronary calcification in patients with rheumatoid arthritis and systemic lupus erythematosus
    K H Yiu
    Department of Medicine, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong
    Clin Exp Rheumatol 30:345-50. 2012
    ....
  23. doi request reprint Ethnic differences in cardiovascular risk in rheumatic disease: focus on Asians
    Kai Hang Yiu
    Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Nat Rev Rheumatol 7:609-18. 2011
    ..We also discuss the burden of CVD, as evaluated using various surrogate markers in these patients, and their overall CVD mortality rate...
  24. ncbi request reprint Antiphospholipid antibody profiles and their clinical associations in Chinese patients with systemic lupus erythematosus
    Mo Yin Mok
    Department of Medicine, and the Clinical Trials Centre, Queen Mary Hospital, Hong Kong
    J Rheumatol 32:622-8. 2005
    ....
  25. ncbi request reprint Elevated plasma adrenomedullin and vascular manifestations in patients with systemic sclerosis
    Mo Yin Mok
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    J Rheumatol 34:2224-9. 2007
    ..We examined associations between ADM concentrations and vascular manifestations in a cohort of patients with SSc...
  26. ncbi request reprint Mannose-binding lectin and susceptibility to infection in Chinese patients with systemic lupus erythematosus
    Mo Yin Mok
    Department of Medicine, Queen Mary Hospital, Hong Kong
    J Rheumatol 34:1270-6. 2007
    ....
  27. doi request reprint Distinct roles of myeloid and plasmacytoid dendritic cells in systemic lupus erythematosus
    Vera Sau Fong Chan
    Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong
    Autoimmun Rev 11:890-7. 2012
    ..The recent surge of interest in studying microRNA regulation in SLE pathogenesis will also be discussed...
  28. doi request reprint Systemic lupus erythematosus patients have increased number of circulating plasmacytoid dendritic cells, but decreased myeloid dendritic cells with deficient CD83 expression
    Ou Jin
    Division of Rheumatology and Clinical Immunology, Department of Medicine, The University of Hong Kong, Hong Kong, China
    Lupus 17:654-62. 2008
    ..In SLE, the increased number of circulating pDCs supports a pathogenic role for these cells, and the decreased mDC number and CD83 expression may explain the susceptibility to infections in these patients...
  29. ncbi request reprint Periodontal status of adults with systemic sclerosis: case-control study
    W Keung Leung
    Prince Philip Dental Hospital, Faculty of Dentistry, The University of Hong Kong, Hong Kong SAR, China
    J Periodontol 82:1140-5. 2011
    ..This project aims to compare the periodontal status of dentate Hong Kong Chinese with and without SSc...
  30. doi request reprint Degos' disease: a rare condition simulating rheumatic diseases
    Ho Yin Chung
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pok Fu Lam, Hong Kong, China
    Clin Rheumatol 28:861-3. 2009
    ..Our patient was put on aspirin but suffered from recurrent bowel infarction 1.5 years later and eventually succumbed to septic complications...
  31. doi request reprint The burden and measurement of cardiovascular disease in SSc
    Mo Yin Mok
    Division of Rheumatology and Clinical Immunology, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China
    Nat Rev Rheumatol 6:430-4. 2010
    ..In addition, these measurements will facilitate trials of therapeutic strategies that, in addition to controlling conventional risk factors, prevent and treat cardiovascular disease in patients with SSc...
  32. pmc Management of rheumatoid arthritis: consensus recommendations from the Hong Kong Society of Rheumatology
    Chi Chiu Mok
    Department of Medicine, Tuen Mun Hospital, Tuen Mun, Hong Kong
    Clin Rheumatol 30:303-12. 2011
    ....
  33. ncbi request reprint Pregnancy outcome in patients with adult onset Still's disease
    Mo Yin Mok
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    J Rheumatol 31:2307-9. 2004
    ..Most did not respond satisfactorily to nonsteroidal antiinflammatory agents alone, but responded to administration of corticosteroids, especially in high doses...