Research Topics
| Grainne M McAlonanSummaryAffiliation: University of Hong Kong Country: China Publications
| Collaborators
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Detail Information
Publications
Mapping the brain in autism. A voxel-based MRI study of volumetric differences and intercorrelations in autismGrainne M McAlonan
Department of Psychiatry, University of Hong Kong, Pokfulam, Hong Kong, SAR China
Brain 128:268-76. 2005..Taken together, our data suggest abnormalities in the anatomy and connectivity of limbic-striatal 'social' brain systems which may contribute to the brain metabolic differences and behavioural phenotype in autism...
Age-related grey matter volume correlates of response inhibition and shifting in attention-deficit hyperactivity disorderGrainne M McAlonan
Department of Psychiatry, University of Hong Kong, Pokfulam, Hong Kong
Br J Psychiatry 194:123-9. 2009..Children with attention-deficit hyperactivity disorder (ADHD) have difficulties with executive function and impulse control which may improve with age...
The timing and specificity of prenatal immune risk factors for autism modeled in the mouse and relevance to schizophreniaGrainne M McAlonan
Department of Psychiatry, The University of Hong Kong, Hong Kong, SAR, China
Neurosignals 18:129-39. 2010....
Differential effects on white-matter systems in high-functioning autism and Asperger's syndromeG M McAlonan
State Key Laboratory for Brain and Cognitive Sciences, University of Hong Kong, Pokfulam, Hong Kong SAR China
Psychol Med 39:1885-93. 2009..White-matter maldevelopment is associated with autism and disconnectivity theories of autism are compelling. However, it is unknown whether children with ASP and HFA have distinct white-matter abnormalities...
Distinct patterns of grey matter abnormality in high-functioning autism and Asperger's syndromeGrainne M McAlonan
Department of Psychiatry, University of Hong Kong, Pokfulam, Hong Kong SAR China
J Child Psychol Psychiatry 49:1287-95. 2008..We therefore planned to examine a whole brain hypothesis that the patterns of grey matter differences in Asperger's syndrome and HFA can be distinguished...
Mapping brain structure in attention deficit-hyperactivity disorder: a voxel-based MRI study of regional grey and white matter volumeGrainne M McAlonan
Department of Psychiatry, University of Hong Kong
Psychiatry Res 154:171-80. 2007..Overall, restricted structural brain abnormalities caused by ADHD were localized to brain systems known to be necessary for attention and executive function...
Spatiotemporal dipole source localization of face processing ERPs in adolescents: a preliminary studyTeresa Ka Wai Wong
Department of Psychiatry, The University of Hong Kong, Pokfulam, Hong Kong
Behav Brain Funct 5:16. 2009..abstract:..
Maturation of social attribution skills in typically developing children: an investigation using the social attribution taskZhouyi Hu
Neuropsychology and Applied Cognitive Neuroscience Laboratory, Department of Psychology, Sun Yat Sen University, Guangzhou, China
Behav Brain Funct 6:10. 2010..Therefore the present study aimed to map the trajectory of social attribution skill acquisition in typically developing children from a young age...
Immediate and sustained psychological impact of an emerging infectious disease outbreak on health care workersGrainne M McAlonan
Department of Psychiatry, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China
Can J Psychiatry 52:241-7. 2007..To assess the immediate and sustained psychological health of health care workers who were at high risk of exposure during the severe acute respiratory syndrome (SARS) outbreak...
Voxel-based analysis of postnatal white matter microstructure in mice exposed to immune challenge in early or late pregnancyQi Li
Department of Psychiatry, University of Hong Kong, Pok Fu Lam, Hong Kong
Neuroimage 52:1-8. 2010..Moreover, FA changes were more extensive in the group exposed earliest in gestation...
Psychological effects of the SARS outbreak in Hong Kong on high-risk health care workersSiew E Chua
Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, SAR, China
Can J Psychiatry 49:391-3. 2004..To quantify stress and the psychological impact of severe acute respiratory syndrome (SARS) on high-risk health care workers (HCWs)...
Stress and psychological distress among SARS survivors 1 year after the outbreakAntoinette M Lee
Department of Psychiatry, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China
Can J Psychiatry 52:233-40. 2007..Our study examined the stress level and psychological distress of severe acute respiratory syndrome (SARS) survivors 1 year after the outbreak...
Psychological responses to the SARS outbreak in healthcare students in Hong KongJosephine G W S Wong
Department of Psychiatry, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
Med Teach 26:657-9. 2004..Suitable psychological and occupational support services should be made available in case of future outbreaks...
Cerebral grey, white matter and csf in never-medicated, first-episode schizophreniaSiew E Chua
Department of Psychiatry, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, S A R China
Schizophr Res 89:12-21. 2007..Ratio of lateral ventricle to caudate volume was bilaterally significantly increased (p<0.005, 2-tailed), which could represent an early biomarker in first-episode, never-medicated schizophrenia...
A naturalistic study of grey matter volume increase after early treatment in anti-psychotic naïve, newly diagnosed schizophreniaMichelle Y Deng
Department of Psychiatry, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Hong Kong, Hong Kong
Psychopharmacology (Berl) 206:437-46. 2009..Anti-psychotic treatment appears to be associated with striatal volume increase, but how early this change occurs is still unknown...
Can Asperger syndrome be distinguished from autism? An anatomic likelihood meta-analysis of MRI studiesKevin K Yu
Department of Psychiatry, The University of Hong Kong, Pokfulam, Hong Kong
J Psychiatry Neurosci 36:412-21. 2011..It capitalizes on the voxel-based morphometry (VBM) approach to systematically explore the whole brain for anatomic correlates of delay and no delay in language acquisition in people with autism spectrum disorders...
Not only dopamine D2 receptors involved in Peony-Glycyrrhiza Decoction, an herbal preparation against antipsychotic-associated hyperprolactinemiaDi Wang
School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China
Prog Neuropsychopharmacol Biol Psychiatry 39:332-8. 2012..This experimental evidence supports clinical use of PGD as an effective treatment of antipsychotic-induced hyperPRL...
MRI study of minor physical anomaly in childhood autism implicates aberrant neurodevelopment in infancyCharlton Cheung
Department of Psychiatry, The University of Hong Kong, Pokfulam, Hong Kong
PLoS ONE 6:e20246. 2011..We hypothesized that optical MPAs might afford a retrospective 'window' to early neurodevelopment; specifically, inter-orbital distance increase may represent a biomarker for early brain dysmaturation in autism...
MR Diffusion Tensor Imaging Detects Rapid Microstructural Changes in Amygdala and Hippocampus Following Fear Conditioning in MiceAbby Y Ding
Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Hong Kong SAR, China Department of Electrical and Electronic Engineering, The University of Hong Kong, Hong Kong SAR, China
PLoS ONE 8:e51704. 2013..However, whether early changes in fear circuits can be captured invivo is not known...
Brain anatomical abnormalities in high-risk individuals, first-episode, and chronic schizophrenia: an activation likelihood estimation meta-analysis of illness progressionRaymond C K Chan
Department of Psychiatry, University of Hong Kong, Hong Kong Special Administrative Region, China
Schizophr Bull 37:177-88. 2011..We predicted that gray matter abnormalities would show progressive changes, with most extensive abnormalities in the chronic group relative to FES and least in the high-risk group...
Prenatal immune challenge is an environmental risk factor for brain and behavior change relevant to schizophrenia: evidence from MRI in a mouse modelQi Li
Department of Psychiatry, University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China
PLoS ONE 4:e6354. 2009..The present experiments tested the hypothesis that there is a causal relationship between prenatal immune challenge and emergence of ventricular abnormalities relevant to schizophrenia in adulthood...
Abnormal spatiotemporal processing of emotional facial expressions in childhood autism: dipole source analysis of event-related potentialsTeresa K W Wong
Department of Psychiatry, The University of Hong Kong, Pokfulam, Hong Kong
Eur J Neurosci 28:407-16. 2008....
Magnetic resonance spectroscopy reveals N-acetylaspartate reduction in hippocampus and cingulate cortex after fear conditioningIris Y Zhou
Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Hong Kong Special Administrative Region, China
Psychiatry Res 204:178-83. 2012..The neurochemical changes characterized by 1H MRS can shed light on the biochemical mechanisms of learning and memory. Moreover, such information can potentially facilitate prompt intervention for patients with psychiatric disorders...
Stress and psychological impact on SARS patients during the outbreakSiew E Chua
Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, SAR, China
Can J Psychiatry 49:385-90. 2004..To examine stress and psychological impact in severe acute respiratory syndrome (SARS) patients during the 2003 outbreak. SARS is a novel, highly infectious pneumonia, and its psychological impact is still unclear...
Neural acupuncture unit: a new concept for interpreting effects and mechanisms of acupunctureZhang Jin Zhang
School of Chinese Medicine, LKS Faculty of Medicine, The University of Hong Kong, 10 Sassoon Road, Pokfulam, Hong Kong
Evid Based Complement Alternat Med 2012:429412. 2012..The introduction of the conception of NAU provides a new theoretical approach to interpreting effects and mechanisms of acupuncture in modern biomedical knowledge framework...
An epidemiological study of concomitant use of Chinese medicine and antipsychotics in schizophrenic patients: implication for herb-drug interactionZhang Jin Zhang
School of Chinese Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong, China
PLoS ONE 6:e17239. 2011..The aim of this epidemiological study was to characterize associations of clinical outcomes with concomitant herbal and antipsychotic use in patients with schizophrenia...
