C-M Lo

Summary

Affiliation: University of Hong Kong
Country: China

Publications

  1. ncbi request reprint Effect of side and size of graft on surgical outcomes of adult-to-adult live donor liver transplantation
    See Ching Chan
    Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 13:91-8. 2007
  2. ncbi request reprint Documented deaths of hepatic lobe donors for living donor liver transplantation
    James F Trotter
    University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Liver Transpl 12:1485-8. 2006
  3. pmc Role of portal vein embolization in hepatocellular carcinoma management and its effect on recurrence: a case-control study
    Rohan C Siriwardana
    Department of Surgery, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, People s Republic of China
    World J Surg 36:1640-6. 2012
  4. ncbi request reprint Liver transplantation for chronic hepatitis B with lamivudine-resistant YMDD mutant using add-on adefovir dipivoxil plus lamivudine
    Chung Mau Lo
    Center for the Study of Liver Disease and the Departments of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Liver Transpl 11:807-13. 2005
  5. ncbi request reprint Liver transplantation for hepatocellular carcinoma
    C M Lo
    Department of Surgery, The University of Hong Kong Medical Centre, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Br J Surg 91:131-3. 2004
  6. ncbi request reprint The role and limitation of living donor liver transplantation for hepatocellular carcinoma
    Chung Mau Lo
    Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 10:440-7. 2004
  7. ncbi request reprint Fibrosing cholestatic hepatitis secondary to precore/core promoter hepatitis B variant with lamivudine resistance: successful retransplantation with combination adefovir dipivoxil and hepatitis B immunoglobulin
    Chung Mau Lo
    Centre for the Study of Liver Disease, and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 10:557-63. 2004
  8. ncbi request reprint Failure of hepatitis B vaccination in patients receiving lamivudine prophylaxis after liver transplantation for chronic hepatitis B
    Chung Mau Lo
    Centre for the Study of Liver Disease, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    J Hepatol 43:283-7. 2005
  9. pmc A randomized, controlled trial of postoperative adjuvant interferon therapy after resection of hepatocellular carcinoma
    Chung Mau Lo
    Centre for the Study of Liver Disease and the Department of Surgery, University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Ann Surg 245:831-42. 2007
  10. ncbi request reprint Efficacy of a pre-S containing vaccine in patients receiving lamivudine prophylaxis after liver transplantation for chronic hepatitis B
    C M Lo
    Centre for the Study of Liver Disease, The University of Hong Kong, Pokfulam, Hong Kong, China
    Am J Transplant 7:434-9. 2007

Detail Information

Publications72

  1. ncbi request reprint Effect of side and size of graft on surgical outcomes of adult-to-adult live donor liver transplantation
    See Ching Chan
    Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 13:91-8. 2007
    ..However, despite similar GW/ESLV, the more arduous recovery and higher mortality rate of left liver recipients raise the caution of assuming the gram-to-gram equivalence of right and left liver grafts...
  2. ncbi request reprint Documented deaths of hepatic lobe donors for living donor liver transplantation
    James F Trotter
    University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Liver Transpl 12:1485-8. 2006
    ....
  3. pmc Role of portal vein embolization in hepatocellular carcinoma management and its effect on recurrence: a case-control study
    Rohan C Siriwardana
    Department of Surgery, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, People s Republic of China
    World J Surg 36:1640-6. 2012
    ..Liver regeneration that occurs after portal vein embolization (PVE) may have adverse effects on the microscopic tumor foci in the residual liver mass in patients with hepatocellular carcinoma (HCC)...
  4. ncbi request reprint Liver transplantation for chronic hepatitis B with lamivudine-resistant YMDD mutant using add-on adefovir dipivoxil plus lamivudine
    Chung Mau Lo
    Center for the Study of Liver Disease and the Departments of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Liver Transpl 11:807-13. 2005
    ..The cost effectiveness of additional passive immunoprophylaxis remains to be defined...
  5. ncbi request reprint Liver transplantation for hepatocellular carcinoma
    C M Lo
    Department of Surgery, The University of Hong Kong Medical Centre, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Br J Surg 91:131-3. 2004
  6. ncbi request reprint The role and limitation of living donor liver transplantation for hepatocellular carcinoma
    Chung Mau Lo
    Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 10:440-7. 2004
    ..14 to 0.90; P =.029). In conclusion, although complicated factors such as donor voluntarism and selection criteria limit the role of LDLT for HCC, LDLT allows more patients to undergo early transplantation and results in a better outcome...
  7. ncbi request reprint Fibrosing cholestatic hepatitis secondary to precore/core promoter hepatitis B variant with lamivudine resistance: successful retransplantation with combination adefovir dipivoxil and hepatitis B immunoglobulin
    Chung Mau Lo
    Centre for the Study of Liver Disease, and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 10:557-63. 2004
    ..With combination of adefovir and high-dose HBIG, however, long-term survival can be achieved after retransplantation...
  8. ncbi request reprint Failure of hepatitis B vaccination in patients receiving lamivudine prophylaxis after liver transplantation for chronic hepatitis B
    Chung Mau Lo
    Centre for the Study of Liver Disease, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    J Hepatol 43:283-7. 2005
    ..Lamivudine prophylaxis against hepatitis B virus (HBV) reinfection after liver transplantation is associated with recurrence due to escape mutants...
  9. pmc A randomized, controlled trial of postoperative adjuvant interferon therapy after resection of hepatocellular carcinoma
    Chung Mau Lo
    Centre for the Study of Liver Disease and the Department of Surgery, University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Ann Surg 245:831-42. 2007
    ..We conducted a randomized controlled trial of adjuvant interferon therapy in patients with predominantly hepatitis B-related hepatocellular carcinoma (HCC) to investigate whether the prognosis after hepatic resection could be improved...
  10. ncbi request reprint Efficacy of a pre-S containing vaccine in patients receiving lamivudine prophylaxis after liver transplantation for chronic hepatitis B
    C M Lo
    Centre for the Study of Liver Disease, The University of Hong Kong, Pokfulam, Hong Kong, China
    Am J Transplant 7:434-9. 2007
    ..At the end of the study, all patients remained seronegative for HBsAg. In conclusion, Sci-B-Vac is effective in about 50% of patients receiving lamividine prophylaxis and may prevent recurrence due to escape mutants...
  11. pmc Lessons learned from one hundred right lobe living donor liver transplants
    Chung Mau Lo
    Centre for the Study of Liver Disease, and Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Ann Surg 240:151-8. 2004
    ..To evaluate the first 100 adult right lobe living donor liver transplants (LDLT) in a single center to determine whether the results have improved with technical modifications and better experience...
  12. ncbi request reprint Nonalcoholic steatohepatitis in donors for living donor liver transplantation
    Chung Mau Lo
    Centre for the Study of Liver Disease, and Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Transplantation 83:265-6. 2007
  13. pmc Liver transplantation in Asian patients with chronic hepatitis B using lamivudine prophylaxis
    C M Lo
    Centre of Liver Diseases, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Ann Surg 233:276-81. 2001
    ..To report the results of liver transplantation in 31 Asian patients with chronic hepatitis B using lamivudine prophylaxis in an open-label study...
  14. ncbi request reprint Living donor versus deceased donor liver transplantation for early irresectable hepatocellular carcinoma
    C M Lo
    Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Br J Surg 94:78-86. 2007
    ..The aim of this study was to compare the outcome after LDLT with that after DDLT, and to identify factors that might account for any differences...
  15. ncbi request reprint Randomized controlled trial of transarterial lipiodol chemoembolization for unresectable hepatocellular carcinoma
    Chung Mau Lo
    Center for the Study of Liver Disease, University of Hong Kong Medical Center, Queen Mary Hospital, Hong Kong, China
    Hepatology 35:1164-71. 2002
    ..In conclusion, in Asian patients with unresectable hepatocellular carcinoma, transarterial Lipiodol chemoembolization significantly improves survival and is an effective form of treatment...
  16. ncbi request reprint Development of antibody to hepatitis B surface antigen after liver transplantation for chronic hepatitis B
    Chung Mau Lo
    Department of Surgery, Center for the Study of Liver Disease, University of Hong Kong Medical Center, Queen Mary Hospital, China
    Hepatology 37:36-43. 2003
    ..The antibody is likely to be of donor origin, suggesting the possibility of adoptive immunity transfer through a liver graft...
  17. ncbi request reprint Safety and outcome of hepatitis B core antibody-positive donors in right-lobe living donor liver transplantation
    Chung Mau Lo
    Department of Surgery, Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Hong Kong, China
    Liver Transpl 9:827-32. 2003
    ..All donors had completely normal liver function at a median follow-up of 31 months (range, 21 to 76 months). A positive serological test result for anti-HBc should not be regarded as a contraindication for right-lobe liver donation...
  18. ncbi request reprint Complications and long-term outcome of living liver donors: a survey of 1,508 cases in five Asian centers
    Chung Mau Lo
    Centre for the Study of Liver Disease and the Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Transplantation 75:S12-5. 2003
    ..The long-term outcome of liver donation, however, remains unknown, and transplant centers should continue their follow-up of donors...
  19. ncbi request reprint Prophylaxis and treatment of recurrent hepatitis B after liver transplantation
    Chung Mau Lo
    Centre for the Study of Liver Disease and the Department of Surgery, University of Hong Kong Medical Center, Queen Mary Hospital, Hong Kong, China
    Transplantation 75:S41-4. 2003
    ....
  20. ncbi request reprint Hepatic venoplasty in living-donor liver transplantation using right lobe graft with middle hepatic vein
    Chung Mau Lo
    Centre for the Study of Liver Disease and Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Transplantation 75:358-60. 2003
    ..This hepatic venoplasty technique can be applied systemically as a standard one in right lobe liver graft with the middle hepatic vein to simplify the recipient hepatectomy and to obviate venous outflow obstruction...
  21. ncbi request reprint Portal hyperperfusion injury as the cause of primary nonfunction in a small-for-size liver graft-successful treatment with splenic artery ligation
    Chung Mau Lo
    Department of Surgery, and Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Hong Kong
    Liver Transpl 9:626-8. 2003
    ..Splenic artery ligation is a technically simple procedure that can be applied for the prevention or treatment of such injury...
  22. ncbi request reprint Significance of hepatitis B virus genotype in liver transplantation for chronic hepatitis B
    Chung Mau Lo
    Department of Surgery, Centre for the Study of Liver Disease, The University of Hong Kong, Pokfulam, Hong Kong, China
    Am J Transplant 5:1893-900. 2005
    ....
  23. ncbi request reprint 48 weeks pegylated interferon alpha-2a is superior to 24 weeks of pegylated interferon alpha-2b in achieving hepatitis B e antigen seroconversion in chronic hepatitis B infection
    C K Hui
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China
    Aliment Pharmacol Ther 23:1171-8. 2006
    ..Although 48-week therapy with pegylated-interferons has been shown to be effective for the treatment of chronic hepatitis B virus infection, the efficacy of a shorter duration of therapy with pegylated interferons is unknown...
  24. ncbi request reprint Laparoscopic resection of a pancreatic polypeptidoma with a solitary liver metastasis
    W F Chan
    Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Pokfulam Road, Hong Kong, China
    Surg Endosc 18:554-6. 2004
    ..A patient undergoing concomitant laparoscopic distal pancreatectomy and hepatectomy for pancreatic polypeptidoma with a solitary liver metastasis is reported...
  25. ncbi request reprint Natural history of patients with recurrent chronic hepatitis C virus and occult hepatitis B co-infection after liver transplantation
    C K Hui
    Department of Medicine, The University of Hong Kong, Hong Kong SAR, China
    Am J Transplant 6:1600-8. 2006
    ..97). In conclusion, occult hepatitis B virus co-infection in patients with recurrent chronic hepatitis C infection was not associated with accelerated fibrosis progression or severe fibrosis after liver transplantation...
  26. pmc Clinicopathological significance of homeoprotein Six1 in hepatocellular carcinoma
    K T Ng
    Centre for the Study of Liver Disease and Departments of Surgery, The University of Hong Kong, Queen Mary Hospital, L9 55, Faculty of Medicine Building, 21 Sassoon Road, Pokfulam, Hong Kong, China
    Br J Cancer 95:1050-5. 2006
    ..004) and poor overall survival (P=0.0423). We concluded that Six1 is frequently overexpressed in HCC patients and elevated Six1 protein in HCC patients may be an indication of advanced stage and poor overall survival after hepatectomy...
  27. ncbi request reprint Effects of the intermittent Pringle manoeuvre on hepatic gene expression and ultrastructure in a randomized clinical study
    K Man
    Department of Surgery, Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Br J Surg 90:183-9. 2003
    ..The aim of this study was to investigate hepatic gene expression related to microcirculatory modulation and ultrastructural changes in patients having the intermittent Pringle manoeuvre...
  28. ncbi request reprint Surgical treatment of pancreatic insulinomas in the era of laparoscopy
    C Y Lo
    Department of Surgery, The University of Hong Kong Medical Centre, Queen Mary Hospital, Pokfulam, Hong Kong, China
    Surg Endosc 18:297-302. 2004
    ..This report evaluates our experience with surgical treatment for pancreatic insulinomas in this era of laparoscopy and reviews the application, safety, and outcome of this surgical approach reported in the literature...
  29. pmc Intravenous bolus somatostatin after diagnostic cholangiopancreatography reduces the incidence of pancreatitis associated with therapeutic endoscopic retrograde cholangiopancreatography procedures: a randomised controlled trial
    R T P Poon
    Surgical Endoscopy Unit, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Gut 52:1768-73. 2003
    ..This study evaluated whether intravenous bolus somatostatin given after diagnostic cholangiopancreatography could reduce the incidence of pancreatitis in a group of patients undergoing therapeutic ERCP procedures...
  30. ncbi request reprint Monday blues of deceased-donor liver transplantation
    See Ching Chan
    Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
    Hepatobiliary Pancreat Dis Int 10:26-9. 2011
    ..There is a constant and global shortage of deceased-donor organs for transplantation. Ways to identify areas for securing potential deceased-donor organs may improve the supply and hence benefit more patients in need of transplantation...
  31. ncbi request reprint Marked suppression of tumor growth by FTY720 in a rat liver tumor model: the significance of down-regulation of cell survival Akt pathway
    Kevin T Ng
    Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, PR China
    Int J Oncol 30:375-80. 2007
    ..In addition, we confirmed that FTY720 caused no effect on infiltrated lymphocyte in tumor tissue. We conclude that FTY720 is an effective anticancer agent for liver tumor in a rat model without affecting the immune system of the host...
  32. pmc Difference in tumor invasiveness in cirrhotic patients with hepatocellular carcinoma fulfilling the Milan criteria treated by resection and transplantation: impact on long-term survival
    Ronnie T P Poon
    Centre for the Study of Liver Disease and Department of Surgery, University of Hong Kong, Pokfulam, Hong Kong, China
    Ann Surg 245:51-8. 2007
    ..This study compared the tumor characteristics of patients with HCC within the Milan criteria treated by resection or transplantation, and elucidated their impact on long-term survival...
  33. ncbi request reprint Liver transplantation for hepatocellular carcinoma in Asia
    Vanessa De Villa
    Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Oncologist 12:1321-31. 2007
    ..With the promotion of organ donation, better quantification of the benefit of LDLT for extended indications, and identification of predictors for survival, the practice of liver transplantation for HCC in Asia will continue to evolve...
  34. ncbi request reprint Identification of hepatitis B virus-specific lymphocytes in human liver grafts from HBV-immune donors
    Ying Luo
    Department of Surgery, Centre for the Study of Liver Disease, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 13:71-9. 2007
    ..043). In conclusion, the presence of considerable numbers of donor-derived HBV-specific immunocompetent cells in grafts may account for the adoptive transfer of HBV immunity through liver transplantation...
  35. pmc Toward current standards of donor right hepatectomy for adult-to-adult live donor liver transplantation through the experience of 200 cases
    See Ching Chan
    Centre for the Study of Liver Disease and Department of Surgery, University of Hong Kong, Pokfulam, Hong Kong, China
    Ann Surg 245:110-7. 2007
    ..To define the current standards of donor right hepatectomy, including the middle hepatic vein for adult-to-adult live donor liver transplantation...
  36. ncbi request reprint Management of carcinoma of the gallbladder: a single-institution experience in 16 years
    Siu Yin Chan
    Centre for the Study of Liver Disease, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    J Surg Oncol 97:156-64. 2008
    ..Radical surgery is the only curative treatment for carcinoma of gallbladder. This study aimed to evaluate the outcome of patients with carcinoma of gallbladder managed in a single institution over 16 years...
  37. doi request reprint A decade of right liver adult-to-adult living donor liver transplantation: the recipient mid-term outcomes
    See Ching Chan
    Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China
    Ann Surg 248:411-9. 2008
    ..We analyzed a single center's experience over a decade of right liver living donor liver transplantation (RLDLT)...
  38. ncbi request reprint Ischemia-reperfusion of small liver remnant promotes liver tumor growth and metastases--activation of cell invasion and migration pathways
    Kwan Man
    Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 13:1669-77. 2007
    ..In conclusion, hepatic I/R injury of a small liver remnant exacerbated liver tumor growth and metastasis by marked activation of cell adhesion, invasion, and angiogenesis pathways...
  39. pmc External drainage of pancreatic duct with a stent to reduce leakage rate of pancreaticojejunostomy after pancreaticoduodenectomy: a prospective randomized trial
    Ronnie T P Poon
    Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
    Ann Surg 246:425-33; discussion 433-5. 2007
    ..This single-center prospective randomized trial compared the results of pancreaticoduodenectomy with external drainage stent versus no stent for pancreaticojejunal anastomosis...
  40. doi request reprint Albumin mRNA in plasma predicts post-transplant recurrence of patients with hepatocellular carcinoma
    Siu Tim Cheung
    Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong
    Transplantation 85:81-7. 2008
    ..The former criteria have limited power on prognosis, whereas the latter do not provide complete information until explant is available...
  41. doi request reprint The significance of acute phase small-for-size graft injury on tumor growth and invasiveness after liver transplantation
    Kwan Man
    Departments of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Ann Surg 247:1049-57. 2008
    ..To test the hypothesis that acute phase small-for-size graft injury may promote late phase tumor recurrence after liver transplantation...
  42. ncbi request reprint Liver transplantation for combined hepatocellular cholangiocarcinoma
    Albert Chi Yan Chan
    Department of Surgery, The University of Hong Kong, Hong Kong SAR
    Asian J Surg 30:143-6. 2007
    ..One patient succumbed to distant metastases 16.5 months after liver transplantation whereas the other two patients continued to survive 35 and 25 months after transplantation, respectively...
  43. ncbi request reprint Working up donors for high-urgency and elective adult-to-adult live donor liver transplantation
    See Ching Chan
    Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 13:509-15. 2007
    ..In a region with scarcity of deceased donor liver grafts, careful and expeditious initial donor workup minimizes dropouts from subsequent steps and allows timely transplantation in high-urgency situations...
  44. doi request reprint Survival analysis of patients with transplantable recurrent hepatocellular carcinoma: implications for salvage liver transplant
    Kelvin K Ng
    FRCS Glasg, FRCS Edin, FACS, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Rd, Hong Kong
    Arch Surg 143:68-74; discussion 74. 2008
    ..There is no difference in the survival benefit between salvage liver transplant and nontransplant therapies for recurrent hepatocellular carcinoma (HCC)...
  45. doi request reprint Changing paradigm in the management of hepatocellular carcinoma improves the survival benefit of early detection by screening
    Albert C Y Chan
    Department of Surgery, University of Hong Kong Medical Centre, Hong Kong, China
    Ann Surg 247:666-73. 2008
    ..To evaluate the impact of improved surgical management of hepatocellular carcinoma (HCC) on the survival of patients with screened HCC...
  46. ncbi request reprint Tumor size and operative risks of extended right-sided hepatic resection for hepatocellular carcinoma: implication for preoperative portal vein embolization
    Barbara H Chik
    Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Pokfulam, Hong Kong, China
    Arch Surg 142:63-9; discussion 69. 2007
    ..The present study evaluated the factors associated with increased operative risks in patients who underwent extended right-sided hepatic resection for HCC...
  47. ncbi request reprint Signal transducers and activators of transcription 5b activation enhances hepatocellular carcinoma aggressiveness through induction of epithelial-mesenchymal transition
    Terence K Lee
    Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Cancer Res 66:9948-56. 2006
    ..In conclusion, STAT5b activation enhanced HCC aggressiveness by induction of EMT, which was possibly mediated by HBX activation. STAT5b could serve as a novel molecular target for HCC treatment...
  48. pmc Anterior approach versus conventional approach right hepatic resection for large hepatocellular carcinoma: a prospective randomized controlled study
    Chi Leung Liu
    Centre for the Study of Liver Disease and Department of Surgery, University of Hong Kong, Pokfulam, Hong Kong, China
    Ann Surg 244:194-203. 2006
    ..To evaluate whether major right hepatectomy using the anterior approach technique for large hepatocellular carcinoma (HCC) results in better operative and long-term survival outcomes when compared with the conventional approach technique...
  49. ncbi request reprint Pancreaticoduodenectomy with en bloc portal vein resection for pancreatic carcinoma with suspected portal vein involvement
    Ronnie T Poon
    Department of Surgery and Centre for the Study of Liver Disease, Queen Mary Hospital, University of Hong Kong Medical Centre, Hong Kong, China
    World J Surg 28:602-8. 2004
    ....
  50. ncbi request reprint Insulin in UW solution exacerbates hepatic ischemia / reperfusion injury by energy depletion through the IRS-2 / SREBP-1c pathway
    Xian Liang Li
    Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Hong Kong, China
    Liver Transpl 10:1173-82. 2004
    ..The key enzyme activities of the energy-consuming process of glycogen and fatty acid synthesis as well as lipoprotein metabolism were accelerated by insulin through the IRS-2 / SREBP-1c pathway...
  51. ncbi request reprint Management of hepatocellular carcinoma in renal transplant recipients
    Kenneth S Chok
    Department of Surgery, Centre for the Study of Liver Disease, The University of Hong Kong, Pokfulam, Hong Kong, China
    J Surg Oncol 87:139-42. 2004
    ..The aim of the present study was to review the management and outcome of HCC in renal transplant recipients at a specialized surgical center...
  52. ncbi request reprint Attenuation of small-for-size liver graft injury by FTY720: significance of cell-survival Akt signaling pathway
    Yi Zhao
    Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Am J Transplant 4:1399-407. 2004
    ..In conclusion, FTY720 attenuates small-for-size liver graft injury by activation of cell-survival Akt signaling and down-regulation of the MAPK pathway...
  53. ncbi request reprint Up-regulation of vascular endothelial growth factor (VEGF) in small-for-size liver grafts enhances macrophage activities through VEGF receptor 2-dependent pathway
    Zhen Fan Yang
    Center for the Study of Liver Disease and Department of Surgery, University of Hong Kong, Hong Kong, China
    J Immunol 173:2507-15. 2004
    ..In conclusion, the present study showed that the up-regulated expression of VEGF and its interaction with Flk-1 in small-for-size liver grafts might facilitate the activities of macrophages...
  54. pmc FK 409 ameliorates small-for-size liver graft injury by attenuation of portal hypertension and down-regulation of Egr-1 pathway
    Kwan Man
    Department of Surgery, Centre for the Study of Liver Disease, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Ann Surg 240:159-68. 2004
    ..To investigate whether low-dose nitric oxide donor FK 409 could attenuate small-for-size graft injury in liver transplantation using small-for-size grafts...
  55. ncbi request reprint Tailoring donor hepatectomy per segment 4 venous drainage in right lobe live donor liver transplantation
    See Ching Chan
    Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 10:755-62. 2004
    ..In conclusion, unfavorable venous drainage patterns were one of the independent factors compromising postoperative donor liver function, but was circumvented by preservation of V4b...
  56. ncbi request reprint Interleukin-2 receptor antibody (basiliximab) for immunosuppressive induction therapy after liver transplantation: a protocol with early elimination of steroids and reduction of tacrolimus dosage
    Chi Leung Liu
    Centre for the Study of Liver Disease, and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 10:728-33. 2004
    ..Further studies and long-term follow-up are required to document their potential benefits on hepatitis B and HCC recurrences...
  57. ncbi request reprint Use of elderly donors (> 60 years) for liver transplantation
    Yi Zhao
    Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Medical Centre, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China
    Asian J Surg 27:114-9. 2004
    ..In this study, we reviewed our experience of using elderly brain-dead donor livers, investigating the potential prognostic factors of the donor, and analysing the influence of donor age on early graft function and graft survival...
  58. pmc Extended hepatic resection for hepatocellular carcinoma in patients with cirrhosis: is it justified?
    Ronnie Tung Ping Poon
    Centre for the Study of Liver Disease and Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Ann Surg 236:602-11. 2002
    ..To evaluate the perioperative outcomes and long-term survival of extended hepatic resection for hepatocellular carcinoma (HCC) in patients with cirrhosis...
  59. ncbi request reprint Hepatic resection for incidentaloma
    Chi Leung Liu
    Centre for the Study of Liver Disease and the Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    J Gastrointest Surg 8:785-93. 2004
    ..The diagnosis of malignant disease, especially HCC, should be considered in male patients older than 50 years who present with large hepatic lesions...
  60. ncbi request reprint FTY720 attenuates hepatic ischemia-reperfusion injury in normal and cirrhotic livers
    Kwan Man
    Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Am J Transplant 5:40-9. 2005
    ..In conclusion, FTY720 attenuates ischemia-reperfusion injury in both normal and cirrhotic livers by activation of cell survival Akt signaling and down-regulation of Egr-1 via Raf-MEK-Erk pathway...
  61. ncbi request reprint Safety of donor right hepatectomy without abdominal drainage: a prospective evaluation in 100 consecutive liver donors
    Chi Leung Liu
    Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 11:314-9. 2005
    ..Abdominal drainage is not a mandatory procedure after donor hepatectomy in LDLT...
  62. ncbi request reprint Estimating liver weight of adults by body weight and gender
    See Ching Chan
    Centre for the Study of Liver Disease, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    World J Gastroenterol 12:2217-22. 2006
    ..To estimate the standard liver weight for assessing adequacies of graft size in live donor liver transplantation and remnant liver in major hepatectomy for cancer...
  63. ncbi request reprint Attenuation of acute phase shear stress by somatostatin improves small-for-size liver graft survival
    Xiao Xu
    Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 12:621-7. 2006
    ..In conclusion, low-dose somatostatin rescues small-for-size grafts from acute phase injury in liver transplantation by attenuation of acute-phase shear stress that resulted from transient portal hypertension...
  64. pmc Operative outcomes of adult-to-adult right lobe live donor liver transplantation: a comparative study with cadaveric whole-graft liver transplantation in a single center
    Chi Leung Liu
    Centre for the Study of Liver, University of Hong Kong, Pokfulam, Hong Kong, China
    Ann Surg 243:404-10. 2006
    ..To evaluate and compare the operative and survival outcomes of patients who underwent right lobe live donor liver transplantation (RLDLT) and cadaveric whole-graft liver transplant (CWLT) recipients in a single institution...
  65. ncbi request reprint Long-term biological consequences of donor right hepatectomy including the middle hepatic vein in adult-to-adult live donor liver transplantation
    See Ching Chan
    Centre for the Study of Liver Disease, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Liver Transpl 12:259-63. 2006
    ..In conclusion, donor right hepatectomy including the middle hepatic vein is biologically acceptable to the live donor...
  66. ncbi request reprint Comparison of early endoscopic ultrasonography and endoscopic retrograde cholangiopancreatography in the management of acute biliary pancreatitis: a prospective randomized study
    Chi Leung Liu
    Centre for the Study of Liver Disease, The University of Hong Kong, Hong Kong, China
    Clin Gastroenterol Hepatol 3:1238-44. 2005
    ..We report a large prospective randomized study comparing early EUS and endoscopic retrograde cholangiopancreatography (ERCP) in the management of these patients...
  67. ncbi request reprint Natural history of untreated nonsurgical hepatocellular carcinoma
    Yuk Pang Yeung
    Department of Surgery, Kwong Wah Hospital, and Centre for the Study of Liver Disease, China
    Am J Gastroenterol 100:1995-2004. 2005
    ..We studied the natural history of untreated nonsurgical HCC to examine whether the prognosis has changed with improved supportive treatment and to identify factors affecting survival...
  68. pmc Improving perioperative outcome expands the role of hepatectomy in management of benign and malignant hepatobiliary diseases: analysis of 1222 consecutive patients from a prospective database
    Ronnie T Poon
    Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
    Ann Surg 240:698-708; discussion 708-10. 2004
    ..To assess the trends in perioperative outcome of hepatectomy for hepatobiliary diseases...
  69. ncbi request reprint Better survival in female patients with hepatocellular carcinoma: oral contraceptive pills related?
    Chi Ming Lam
    Department of Surgery, Centre for the Study of Liver Disease, University of Hong Kong, Pokfulam, Hong Kong, China
    J Clin Gastroenterol 39:533-9. 2005
    ..Hepatocellular carcinoma (HCC) has an indisputable male predominance. "Gender" as an independent prognostic factor for survival is, however, controversial...
  70. ncbi request reprint What is the best technique for right hemiliver living donor liver transplantation? With or without the middle hepatic vein? Duct-to-duct biliary anastomosis or Roux-en-Y hepaticojejunostomy?
    Chi Leung Liu
    Department of Surgery, Centre for the Study of Liver Disease, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Pokfulam, Hong Kong, China
    J Hepatol 43:17-22. 2005
  71. ncbi request reprint The influence of phosphatidylinositol 3-kinase/Akt pathway on the ischemic injury during rat liver graft preservation
    Xian Liang Li
    Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Pokfulam, Republic of China
    Am J Transplant 5:1264-75. 2005
    ..In conclusion, PI3-kinase/Akt pathway was dysregulated and contributed to ischemic injury during preservation. Heparin and LY294002 could improve graft viability by maintaining calcium homeostasis during preservation...
  72. pmc Long-term survival and pattern of recurrence after resection of small hepatocellular carcinoma in patients with preserved liver function: implications for a strategy of salvage transplantation
    Ronnie Tung Ping Poon
    Centre for the Study of Liver Disease and Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, China
    Ann Surg 235:373-82. 2002
    ....