Research Topics
Species | Yuqing LiuSummaryAffiliation: University of Hong Kong Country: China Publications
| Collaborators
|
Detail Information
Publications
Blockage of epidermal growth factor receptor by quinazoline tyrosine kinase inhibitors suppresses growth of human hepatocellular carcinomaYuqing Liu
Centre for the Study of Liver Disease, Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
Cancer Lett 248:32-40. 2007..This suggested that blockage of EGF receptors may provide an effective therapeutic approach for human HCC and ANAPD could be a potential drug candidate for the treatment of HCC...
Chemokine receptors support infiltration of lymphocyte subpopulations in human hepatocellular carcinomaYuqing Liu
Department of Surgery, The University of Hong Kong, Centre for the Study of Liver Disease, L9 57, Faculty of Medicine Building, 21 Sassoon Road, Pokfulam, Hong Kong, China
Clin Immunol 114:174-82. 2005..This study demonstrates the role of chemokine receptors in the recruitment of specific lymphocyte subsets to the liver in HCC and suggests the importance of these receptors in regulation of immune defense against HCC...
Reduced expression of chemokine receptors on peripheral blood lymphocytes in patients with hepatocellular carcinomaYuqing Liu
Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, ROC
Am J Gastroenterol 99:1111-21. 2004..The results demonstrated the role of chemokine receptors in recruitment of lymphocytes from peripheral blood to HCC. The findings have important implications in understanding of immunopathogenesis of HCC...
PTK787/ZK22258 attenuates stellate cell activation and hepatic fibrosis in vivo by inhibiting VEGF signalingYuqing Liu
Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
Lab Invest 89:209-21. 2009..These findings provide novel insights into the potential value of blocking VEGF signaling by a small molecule tyrosine kinase inhibitor in treating hepatic fibrosis...
High doses of tyrosine kinase inhibitor PTK787 enhance the efficacy of ischemic hypoxia for the treatment of hepatocellular carcinoma: dual effects on cancer cell and angiogenesisZhen Fan Yang
Center for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
Mol Cancer Ther 5:2261-70. 2006..In conclusion, PTK787 combined with hypoxia achieved a better therapeutic efficacy than hypoxia alone through enhancing hypoxia-induced antitumor cell effect and preventing the activation of angiogenic process...
Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist NilotinibYuqing Liu
Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
J Hepatol 55:612-25. 2011..Nilotinib is a novel tyrosine kinase inhibitor of Bcr-Abl and other kinases. In this study, we have examined its activity as an anti-fibrotic agent...
Both antiangiogenesis- and angiogenesis-independent effects are responsible for hepatocellular carcinoma growth arrest by tyrosine kinase inhibitor PTK787/ZK222584Yuqing Liu
Centre for the Study of Liver Disease and Department of Surgery, The University of Hong Kong, Pokfulam, Hong Kong, China
Cancer Res 65:3691-9. 2005..Our data suggest that blockage of VEGF receptors may provide an effective therapeutic approach for human hepatocellular carcinoma...
Vitamin k epoxide reductase: a protein involved in angiogenesisYibo Wang
Sino German Laboratory for Molecular Medicine and Hypertension Division, Cardiovascular Institute and Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, 167 Beilishilu, Xicheng District, Beijing 100037, P R China
Mol Cancer Res 3:317-23. 2005..Our findings support the impact of VKOR in the process of angiogenesis; hence, the molecule may have a potential application in cardiovascular disease and cancer therapy...
Effect of physiological heterogeneity of E. coli population on antibiotic susceptivity testYuqing Liu
Institute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Science, Jinan, 250100, China
Sci China C Life Sci 50:808-13. 2007..However there are few reports concerned with this study. Further research using different kinds of antibiotics with synchronized continuous culture of different bacterial strains is required...
CARP is a novel caspase recruitment domain containing pro-apoptotic proteinBaohua Liu
Sino German Laboratory for Molecular Medicine and Center for Molecular Cardiology, Fu Wai Hospital, Chinese Academy of Medical Sciences, 167 Beilishilu, Beijing 100037, China
Biochem Biophys Res Commun 293:1396-404. 2002..Our results suggest that CARP is a novel CARD-containing pro-apoptotic protein...
