C S Lau

Summary

Affiliation: University of Hong Kong
Country: China

Publications

  1. ncbi request reprint Profile of sex hormones in male patients with systemic lupus erythematosus
    C C Mok
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Lupus 9:252-7. 2000
  2. pmc Abnormalities in circulating plasmacytoid dendritic cells in patients with systemic lupus erythematosus
    Ou Jin
    Department of Medicine, The University of Hong Kong, Hong Kong, People s Republic of China
    Arthritis Res Ther 12:R137. 2010
  3. pmc Phenotypic and functional abnormalities of bone marrow-derived dendritic cells in systemic lupus erythematosus
    Ying J Nie
    Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, PR China
    Arthritis Res Ther 12:R91. 2010
  4. ncbi request reprint Ethnic and geographical differences in systemic lupus erythematosus: an overview
    C S Lau
    University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    Lupus 15:715-9. 2006
  5. doi request reprint Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese
    W Yang
    Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
    Genes Immun 10:219-26. 2009
  6. doi request reprint Two missense variants in UHRF1BP1 are independently associated with systemic lupus erythematosus in Hong Kong Chinese
    Y Zhang
    Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China
    Genes Immun 12:231-4. 2011
  7. ncbi request reprint Prognostic role of coronary calcification in patients with rheumatoid arthritis and systemic lupus erythematosus
    K H Yiu
    Department of Medicine, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong
    Clin Exp Rheumatol 30:345-50. 2012
  8. ncbi request reprint Lupus nephritis in Southern Chinese patients: clinicopathologic findings and long-term outcome
    C C Mok
    Division of Rheumatology, Queen Mary Hospital, Pokfulam, Hong Kong
    Am J Kidney Dis 34:315-23. 1999
  9. doi request reprint Prevalence and extent of calcification over aorta, coronary and carotid arteries in patients with rheumatoid arthritis
    S Wang
    Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
    J Intern Med 266:445-52. 2009
  10. doi request reprint Coronary atherosclerosis using computed tomography coronary angiography in patients with systemic sclerosis
    M Y Mok
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, PR China
    Scand J Rheumatol 38:381-5. 2009

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Profile of sex hormones in male patients with systemic lupus erythematosus
    C C Mok
    Department of Medicine, Queen Mary Hospital, Hong Kong
    Lupus 9:252-7. 2000
    ..To study the profile of sex hormones in male patients with systemic lupus erythematosus (SLE)...
  2. pmc Abnormalities in circulating plasmacytoid dendritic cells in patients with systemic lupus erythematosus
    Ou Jin
    Department of Medicine, The University of Hong Kong, Hong Kong, People s Republic of China
    Arthritis Res Ther 12:R137. 2010
    ..However, the functional characteristics of directly isolated peripheral circulating blood pDCs in SLE have not been evaluated previously...
  3. pmc Phenotypic and functional abnormalities of bone marrow-derived dendritic cells in systemic lupus erythematosus
    Ying J Nie
    Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, PR China
    Arthritis Res Ther 12:R91. 2010
    ..However, whether DC abnormalities occur during their development in the bone marrow (BM) or in the periphery is not known...
  4. ncbi request reprint Ethnic and geographical differences in systemic lupus erythematosus: an overview
    C S Lau
    University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    Lupus 15:715-9. 2006
    ..But are these ethnic and geographical differences real? If yes, they may provide investigators insight into the underlying pathoaetiology of this condition and pave the way to future research directions in lupus...
  5. doi request reprint Population differences in SLE susceptibility genes: STAT4 and BLK, but not PXK, are associated with systemic lupus erythematosus in Hong Kong Chinese
    W Yang
    Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
    Genes Immun 10:219-26. 2009
    ..36, OR=1.06, 95% confidence interval: 0.93-1.21). Our study indicates that some of the susceptibility genes for this disease may be population specific...
  6. doi request reprint Two missense variants in UHRF1BP1 are independently associated with systemic lupus erythematosus in Hong Kong Chinese
    Y Zhang
    Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, LKS Faculty of Medicine, The University of Hong Kong, Hong Kong, China
    Genes Immun 12:231-4. 2011
    ..44 x 10⁻⁹, odds ratio=1.49). Cross-population confirmation establishes the involvement of this locus in SLE and indicates that distinct alleles are contributing to disease susceptibility...
  7. ncbi request reprint Prognostic role of coronary calcification in patients with rheumatoid arthritis and systemic lupus erythematosus
    K H Yiu
    Department of Medicine, Queen Mary Hospital, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong
    Clin Exp Rheumatol 30:345-50. 2012
    ....
  8. ncbi request reprint Lupus nephritis in Southern Chinese patients: clinicopathologic findings and long-term outcome
    C C Mok
    Division of Rheumatology, Queen Mary Hospital, Pokfulam, Hong Kong
    Am J Kidney Dis 34:315-23. 1999
    ..Prospective randomized studies with well-defined treatment protocols are needed to delineate the optimal treatment strategy for LN...
  9. doi request reprint Prevalence and extent of calcification over aorta, coronary and carotid arteries in patients with rheumatoid arthritis
    S Wang
    Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
    J Intern Med 266:445-52. 2009
    ..To evaluate the prevalence and pattern of arterial calcification in patients with rheumatoid arthritis (RA)...
  10. doi request reprint Coronary atherosclerosis using computed tomography coronary angiography in patients with systemic sclerosis
    M Y Mok
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, PR China
    Scand J Rheumatol 38:381-5. 2009
    ..Impaired coronary artery reserve has previously been demonstrated in patients with systemic sclerosis (SSc). Both micro- and macrovascular factors are probably contributory to the underlying pathogenesis...
  11. ncbi request reprint Low circulating level of CD133+KDR+cells in patients with systemic sclerosis
    M Y Mok
    Division of Rheumatology and Immunology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Clin Exp Rheumatol 28:S19-25. 2010
    ..Results of previous studies on the level of circulating endothelial progenitor cells (EPCs), which are involved in vascular repair, in scleroderma (SSc) patients have been controversial...
  12. ncbi request reprint Intestinal pseudo-obstruction in systemic lupus erythematosus: an uncommon but important clinical manifestation
    M Y Mok
    Division of Rheumatology, University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    Lupus 9:11-8. 2000
    ..To document intestinal pseudo-obstruction (IpsO) as a recognised clinical manifestation of systemic lupus erythematosus (SLE) and a possible new clinical entity with its apparent association with ureterohydronephrosis...
  13. pmc Association of BANK1 and TNFSF4 with systemic lupus erythematosus in Hong Kong Chinese
    Y K Chang
    Li Ka Shing Faculty of Medicine, Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
    Genes Immun 10:414-20. 2009
    ..26 x 10(-3)), but not vice versa (P=0.55). These findings suggest that multiple independent genetic variants may be present within the gene locus, which exert their effects on SLE pathogenesis through different mechanisms...
  14. ncbi request reprint The efficacy of cevimeline hydrochloride in the treatment of xerostomia in Sjögren's syndrome in southern Chinese patients: a randomised double-blind, placebo-controlled crossover study
    K C M Leung
    Oral Rehabilitation, Faculty of Dentistry, The University of Hong Kong, Hong Kong, China
    Clin Rheumatol 27:429-36. 2008
    ..However, there was no improvement in salivary flow rates and dry eye symptoms. SS patients had lower SF-36 scores, but these did not improve after treatment with cevimeline...
  15. ncbi request reprint Non-tuberculous mycobacterial infection in patients with systemic lupus erythematosus
    M Y Mok
    University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Rheumatology (Oxford) 46:280-4. 2007
    ..To examine the clinical manifestations of non-tuberculous mycobacterial (NTM) infections with those of Mycobacterium tuberculosis (MTB) infections in SLE patients...
  16. ncbi request reprint Clinical characteristics, treatment, and outcome of adult onset Still's disease in southern Chinese
    C C Mok
    Department of Medicine, Queen Mary Hospital, Pokfulam, Hong Kong
    J Rheumatol 25:2345-51. 1998
    ..To study the clinical characteristics, treatment outcome, and complications of patients with adult onset Still's disease (AOSD) in our local Chinese population...
  17. ncbi request reprint Interstitial lung disease in systemic sclerosis
    G C Ooi
    Department of Diagnostic Radiology, The University of Hong Kong, Queen Mary Hospital, SAR China
    Acta Radiol 44:258-64. 2003
    ..To evaluate high-resolution CT (HRCT) parameters of inflammation and fibrosis in systemic sclerosis (SSc), for correlation with lung function, skin scores and exercise tolerance...
  18. ncbi request reprint Necrotizing fasciitis in rheumatic diseases
    M Y Mok
    University Department of Medicine, Queen Mary Hospital, Hong Kong
    Lupus 15:380-3. 2006
    ..5, 95% CI 2.1-27.3, P = 0.01). Timely debridement of necrotic tissue is important for reducing mortality...
  19. ncbi request reprint Use of exogenous estrogens in systemic lupus erythematosus
    C C Mok
    Department of Medicine and Geriatrics, Tuen Mun Hospital and the Department of Medicine, Queen Mary Hospital, Hong Kong
    Semin Arthritis Rheum 30:426-35. 2001
    ..To review the current literature on the safety of using exogenous estrogens in patients with systemic lupus erythematosus (SLE)...
  20. ncbi request reprint Bosentan use in systemic lupus erythematosus patients with pulmonary arterial hypertension
    M Y Mok
    Department of Medicine, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Lupus 16:279-85. 2007
    ..Significantly deranged liver function was found in one patient...
  21. ncbi request reprint Adrenomedullin--a potential disease activity marker and suppressor of nephritis activity in systemic lupus erythematosus
    A Mak
    University Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong SAR, China
    Rheumatology (Oxford) 45:1266-72. 2006
    ....
  22. ncbi request reprint Increased apoptotic neutrophils and macrophages and impaired macrophage phagocytic clearance of apoptotic neutrophils in systemic lupus erythematosus
    Yi Ren
    Queen Mary Hospital, University of Hong Kong, Hong Kong
    Arthritis Rheum 48:2888-97. 2003
    ....
  23. ncbi request reprint Association of interleukin-10 promoter polymorphisms with systemic lupus erythematosus
    W P Chong
    Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China
    Genes Immun 5:484-92. 2004
    ..62-1.78, P=0.848). The frequency of non-ht1 was significantly increased in patients with serositis (P<0.0001, OR=2.42, 95% CI: 1.55-3.80). In conclusion, the high expression promoter genotype is associated with SLE in Chinese...
  24. ncbi request reprint Common NOD2 polymorphisms in Hong Kong Chinese patients with systemic lupus erythematosus
    W P Chong
    Rheumatology (Oxford) 43:104-5. 2004
  25. ncbi request reprint Lupus in Hong Kong Chinese
    C C Mok
    Department of Medicine, Tuen Mun Hospital, New Territories, Hong Kong Special Administrative Region, China
    Lupus 12:717-22. 2003
    ..More grants and funding are being sought for basic and clinical researches in SLE and subsidising patients to receive newer and less toxic treatment options...
  26. pmc Pathogenesis of systemic lupus erythematosus
    C C Mok
    Department of Medicine and Geriatrics, Tuen Mun Hospital, Tsing Chung Koon Road, New Territories, Hong Kong
    J Clin Pathol 56:481-90. 2003
    ..Finally, certain environmental factors are probably required to trigger the disease...
  27. ncbi request reprint Antibodies to mannose binding lectin in patients with systemic lupus erythematosus
    M Y Mok
    Department of Immunology and Molecular Pathology and Rheumatology, Royal Free and University College Medical School, London, UK
    Lupus 13:522-8. 2004
    ..Thus the production of anti-MBL antibodies is likely to be a specific antigen-driven process. Its role in lupus pathogenesis remains to be elucidated...
  28. ncbi request reprint Neuropsychiatric manifestations and their clinical associations in southern Chinese patients with systemic lupus erythematosus
    C C Mok
    Department of Medicine, Tuen Mun Hospital, New Territories, Hong Kong, China
    J Rheumatol 28:766-71. 2001
    ..Seizure and cerebrovascular disorders were the most common NP features. The presence of antiphospholipid antibodies was significantly associated with NP manifestations, especially cerebrovascular disorders...
  29. pmc Clinical predictors of fetal and maternal outcome in Chinese patients with systemic lupus erythematosus
    M Y Mok
    Ann Rheum Dis 63:1705-6. 2004
  30. ncbi request reprint Polymorphisms of the toll-like receptor 9 (TLR9) gene with systemic lupus erythematosus in Chinese
    M W Ng
    Rheumatology (Oxford) 44:1456-7. 2005