Research Topics
Species | Brian Hung Hin LangSummaryAffiliation: University of Hong Kong Country: China Publications
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Detail Information
Publications
Parathyroid carcinoma in a 30-year-old man: a diagnostic and management challengeSze How Ng
Division of Endocrine Surgery, Department of Surgery, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, SAR, China
World J Surg Oncol 11:83. 2013..This case also highlighted several issues, including the challenge of ascertaining the diagnosis before surgery and the dilemma of reoperation after simple excision...- Does using an energized device in open thyroidectomy reduce complications?Brian Hung Hin Lang
Division of Endocrine Surgery, Department of Surgery, University of Hong Kong, Pokfulam, Hong Kong SAR, China
J Surg Res 181:e23-9. 2013.... - Factors affecting the adequacy of lymph node yield in prophylactic unilateral central neck dissection for papillary thyroid carcinomaBrian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
J Surg Oncol 106:966-71. 2012..Determinants for adequate lymph node yield (LNY) in prophylactic central neck dissection (pCND) for papillary thyroid carcinoma (PTC) remain unclear. We aimed to determine factors affecting LNY in pCND... 
A review of risk factors and timing for postoperative hematoma after thyroidectomy: is outpatient thyroidectomy really safe?Brian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
World J Surg 36:2497-502. 2012..With the growing demand for outpatient thyroidectomy, we assessed its safety and feasibility by evaluating the potential risk factors and timing of postoperative hematoma after thyroidectomy...- Risk of second primary malignancy in differentiated thyroid carcinoma treated with radioactive iodine therapyBrian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong, China
Surgery 151:844-50. 2012.... - Feasibility on the use of intraoperative vagal nerve stimulation in gasless, transaxillary endoscopic, and robotic-assisted thyroidectomyBrian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
J Laparoendosc Adv Surg Tech A 21:911-7. 2011.... - A prospective evaluation of quick intraoperative parathyroid hormone assay at the time of skin closure in predicting clinically relevant hypocalcemia after thyroidectomyBrian Hung Hin Lang
Division of Endocrine Surgery, Department of Surgery, University of Hong Kong, Pokfulam, Hong Kong SAR, China
World J Surg 36:1300-6. 2012..e., patients requiring calcium ± calcitriol supplements on hospital discharge)... - Impact of second primary malignancy on outcomes of differentiated thyroid carcinomaBrian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
Surgery 148:1191-6; discussion 1196-7. 2010..This study aimed at evaluating the risk of SPM in patients with differentiated thyroid carcinoma (DTC) and how the timing of SPM might affect the disease course... - A comparison of surgical outcomes between endoscopic and robotically assisted thyroidectomy: the authors' initial experienceBrian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
Surg Endosc 25:1617-23. 2011..The RAT uses the same endoscopic route as the GTET but with the assistance of the da Vinci S robotic system. Excellent results for RAT have been reported, but it remains unclear whether RAT offers any potential benefits over GTET... 
Minimally invasive thyroid and parathyroid operations: surgical techniques and pearlsBrian Hung Hin Lang
Division of Endocrine Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, 102 Pokfulam Road, Pokfulam, Hong Kong SAR, China
Adv Surg 44:185-98. 2010..Unlike MIT, MIP has become the standard approach for surgical management of primary hyperparathyroidism caused by localized solitary parathyroid adenoma...- Risk factors for nonsynchronous second primary malignancy and related death in patients with differentiated thyroid carcinomaBrian Hung Hin Lang
Division of Endocrine Surgery, Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, Hong Kong SAR, China
Ann Surg Oncol 18:3559-65. 2011..This study aims to examine possible risk factors leading to occurrence of NSPM as well as risk factors leading to NSPM-related death in patients with DTC... - Impact of routine unilateral central neck dissection on preablative and postablative stimulated thyroglobulin levels after total thyroidectomy in papillary thyroid carcinomaBrian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong, Hong Kong SAR, China
Ann Surg Oncol 19:60-7. 2012..Because postsurgical stimulated thyroglobulin (sTg) level is a good surrogate for recurrence, the study aimed to evaluate the impact of prophylactic CND on preablative and postablative sTg levels after total thyroidectomy... - The role of 18F-fluorodeoxyglucose positron emission tomography in thyroid neoplasmsBrian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
Oncologist 16:458-66. 2011.... - Papillary microcarcinoma: is there any difference between clinically overt and occult tumors?Chung Yau Lo
Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Pokfulam, Hong Kong, China
World J Surg 30:759-66. 2006..However, clinical and biologic behaviors of PMC may vary considerably between tumors that are clinically overt and those that are occult... - Prognostic factors in papillary and follicular thyroid carcinoma: their implications for cancer stagingBrian Hung Hin Lang
Division of Endocrine Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China
Ann Surg Oncol 14:730-8. 2007..However, this may not be an optimal approach to cancer staging... - Significance of size of lymph node metastasis on postsurgical stimulated thyroglobulin levels after prophylactic unilateral central neck dissection in papillary thyroid carcinomaBrian Hung Hin Lang
Division of Endocrine Surgery, Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
Ann Surg Oncol 19:3472-8. 2012.... - Staging systems for papillary thyroid carcinoma: a review and comparisonBrian Hung Hin Lang
Division of Endocrine Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong SAR, China
Ann Surg 245:366-78. 2007..To find out the most predictive staging system for papillary thyroid carcinoma (PTC) currently available in the literature... - Significance of metastatic lymph node ratio on stimulated thyroglobulin levels in papillary thyroid carcinoma after prophylactic unilateral central neck dissectionBrian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong, Hong Kong SAR, China
Ann Surg Oncol 19:1257-63. 2012.... - Staging systems for follicular thyroid carcinoma: application to 171 consecutive patients treated in a tertiary referral centreBrian Hung Hin Lang
Division of Endocrine Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China
Endocr Relat Cancer 14:29-42. 2007..When predictability was measured by PVE, the TNM system was found to have the best predictability and thus, should be the stratification system of choice for FTC in the future... - Surgical options in undifferentiated thyroid carcinomaBrian Hung Hin Lang
Division of Endocrine Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong, SAR, China
World J Surg 31:969-77. 2007..Because of the ineffectiveness of all conventional treatment modalities, novel molecular targeted therapies are being developed to tackling this uniformly fatal disease with promising results... - Incidental thyroid carcinoma by FDG-PET/CT: a study of clinicopathological characteristicsT T Law
Department of Surgery, University of Hong Kong, Hong Kong SAR, China
Ann Surg Oncol 18:472-8. 2011..The present study aims to critically evaluate the clinicopathological characteristics of ITC detected by FDG-PET/CT... - Is there a role for unstimulated thyroglobulin velocity in predicting recurrence in papillary thyroid carcinoma patients with detectable thyroglobulin after radioiodine ablation?Hilda Wong
Department of Medicine, Division of Hematology and Oncology, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China
Ann Surg Oncol 19:3479-85. 2012..Only limited data on Tg kinetics have been reported to date. Here we aim to evaluate the prognostic and predictive significance of nonstimulated serum Tg velocity (TgV)... - Clinicopathologic predictors for early and late biochemical hypothyroidism after hemithyroidectomyKevin Ka Wan Chu
Division of Endocrine Surgery, Department of Surgery, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China
Am J Surg 203:461-6. 2012..This study aimed to identify potential clinicopathologic risk factors associated with early (<12 months after hemithyroidectomy) and late-onset (≥12 months after hemithyroidectomy) BH... - Eucalcemic parathyroid hormone elevation after parathyroidectomy for primary sporadic hyperparathyroidism: risk factors, trend, and outcomeBrian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
Ann Surg Oncol 19:584-90. 2012..We aimed to examine risk factors, trend of PTH level, and outcome of patients with ePTH 6 months after parathyroidectomy... - Vitamin D3 deficiency is associated with late-onset hypocalcemia after minimally invasive parathyroidectomy in a vitamin D borderline areaBrian Hung Hin Lang
Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China
World J Surg 34:1350-5. 2010..We aimed to examine the clinicopathologic features and short-term outcomes of vitamin D(3)-deficient patients after minimally invasive parathyroidectomy (MIP)... - Staging systems for papillary thyroid carcinoma: a study of 2 tertiary referral centersBrian Hung Hin Lang
From the Division of Endocrine Surgery, Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong SAR, China
Ann Surg 246:114-21. 2007..To find out the most applicable and consistent staging system for papillary thyroid carcinoma (PTC) available in the literature... - Do low preoperative vitamin D levels reduce the accuracy of quick parathyroid hormone in predicting postthyroidectomy hypocalcemia?Brian Hung Hin Lang
Division of Endocrine Surgery, Department of Surgery, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China
Ann Surg Oncol 20:739-45. 2013..Our study aimed to address these issues... - Evaluating the Prognostic Factors Associated with Cancer-specific Survival of Differentiated Thyroid Carcinoma Presenting with Distant MetastasisBrian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
Ann Surg Oncol 20:1329-35. 2013..We aimed to evaluate the prognostic factors affecting cancer-specific survival (CSS) in DTC patients presenting with DM... - Changing trend in surgical indication and management for Graves' diseaseJeremy Yip
Division of Endocrine Surgery, Department of Surgery, University of Hong Kong, Queen Mary Hospital, China
Am J Surg 203:162-7. 2012..This study aimed to evaluate the changes in surgical indication, type of resection, and surgical outcomes at a single institution... - Graves' ophthalmopathy as an indication increased the risk of hypoparathyroidism after bilateral thyroidectomyKai Pun Wong
Division of Endocrine Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, Hong Kong
World J Surg 35:2212-8. 2011..We aimed to evaluate the impact of this indication on surgical outcomes in Graves' disease (GD)... - A phase II trial of vinorelbine and pegylated liposomal doxorubicin in patients with pretreated metastatic breast cancerLouis Wing Cheong Chow
Department of Surgery, The University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong SAR, China
Am J Clin Oncol 30:133-8. 2007..The combination of vinorelbine and PLD for anthracycline- and/or taxane-pretreated patients with MBC is an active and safe regimen that does not compromise the quality of life... - Postablation stimulated thyroglobulin level is an important predictor of biochemical complete remission after reoperative cervical neck dissection in persistent/recurrent papillary thyroid carcinomaBrian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
Ann Surg Oncol 20:653-9. 2013..We hypothesized that lower postablation sTg levels would indicate a higher rate of BCR after RND. Our study examined the association between postablation sTg and BCR after one or more RNDs... - A comparison of surgical morbidity and scar appearance between gasless, transaxillary endoscopic thyroidectomy (GTET) and minimally invasive video-assisted thyroidectomy (VAT)Brian Hung Hin Lang
Department of Surgery, The University of Hong Kong, Hong Kong SAR, China
Ann Surg Oncol 20:646-52. 2013..The present study was designed to compare surgical morbidities/complications and scar appearance between GTET and VAT at our institution... - New molecular targeted therapy and redifferentiation therapy for radioiodine-refractory advanced papillary thyroid carcinoma: literature reviewKai Pun Wong
Division of Endocrine Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, Hong Kong
J Thyroid Res 2012:818204. 2012..The aim of the review was to summarize and discuss the results of these targeted drugs and redifferentiation agents for patients with progressive, radioiodine-refractory papillary thyroid carcinoma... - The potential clinical relevance of serum vascular endothelial growth factor (VEGF) and VEGF-C in recurrent papillary thyroid carcinomaXiao Min Yu
Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
Surgery 144:934-40; discussion 940-1. 2008..This study aims at evaluating serum VEGF (sVEGF) and sVEGF-C levels in recurrent papillary thyroid carcinoma (PTC) patients... - The role of prophylactic central neck dissection in differentiated thyroid carcinoma: issues and controversiesKai Pun Wong
Division of Endocrine Surgery, Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Hong Kong
J Oncol 2011:127929. 2011..Performing a unilateral pCND may be better than a bilateral pCND given its lower surgical morbidity. Further studies in this controversial subject are much needed...