Mary Sau-man Ip

Summary

Affiliation: University of Hong Kong
Country: China

Publications

  1. pmc Altered profile of circulating endothelial progenitor cells in obstructive sleep apnea
    Macy Mei sze Lui
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Sleep Breath 17:937-42. 2013
  2. doi request reprint Significance of endothelial dysfunction in sleep-related breathing disorder
    Macy Mei sze Lui
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Respirology 18:39-46. 2013
  3. ncbi request reprint Lung function reference values in Chinese children and adolescents in Hong Kong. II. Prediction equations for plethysmographic lung volumes
    M S Ip
    Departments of Medicine, Orthopedic Surgery, and Pediatrics, The University of Hong Kong, Hong Kong SAR, China
    Am J Respir Crit Care Med 162:430-5. 2000
  4. ncbi request reprint Reference values of diffusing capacity of non-smoking Chinese in Hong Kong
    Mary S M Ip
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China
    Respirology 12:599-606. 2007
  5. ncbi request reprint Updated spirometric reference values for adult Chinese in Hong Kong and implications on clinical utilization
    Mary Sau Man Ip
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China
    Chest 129:384-92. 2006
  6. ncbi request reprint A community study of sleep-disordered breathing in middle-aged Chinese women in Hong Kong: prevalence and gender differences
    Mary S M Ip
    Departments of Medicine, The University of Hong Kong, Hong Kong, SAR, China
    Chest 125:127-34. 2004
  7. ncbi request reprint Endothelial function in obstructive sleep apnea and response to treatment
    Mary S M Ip
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
    Am J Respir Crit Care Med 169:348-53. 2004
  8. ncbi request reprint Obstructive sleep apnea is independently associated with insulin resistance
    Mary S M Ip
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong S A R, PR China
    Am J Respir Crit Care Med 165:670-6. 2002
  9. ncbi request reprint A community study of sleep-disordered breathing in middle-aged Chinese men in Hong Kong
    M S Ip
    Department of Medicine, The University of Hong Kong, Hong Kong, SAR, China
    Chest 119:62-9. 2001
  10. ncbi request reprint Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by nasal continuous positive airway pressure
    M S Ip
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
    Am J Respir Crit Care Med 162:2166-71. 2000

Collaborators

Detail Information

Publications43

  1. pmc Altered profile of circulating endothelial progenitor cells in obstructive sleep apnea
    Macy Mei sze Lui
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Sleep Breath 17:937-42. 2013
    ..Our study evaluates changes in endothelial progenitor cell (EPC) profile in relation to OSA and the role of advanced glycation end-products (AGE) in this relationship...
  2. doi request reprint Significance of endothelial dysfunction in sleep-related breathing disorder
    Macy Mei sze Lui
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Respirology 18:39-46. 2013
    ..Evidence-based information will allow us to construct the framework for guiding individualized clinical management and public health strategies for OSA, as well as cardiometabolic diseases...
  3. ncbi request reprint Lung function reference values in Chinese children and adolescents in Hong Kong. II. Prediction equations for plethysmographic lung volumes
    M S Ip
    Departments of Medicine, Orthopedic Surgery, and Pediatrics, The University of Hong Kong, Hong Kong SAR, China
    Am J Respir Crit Care Med 162:430-5. 2000
    ..These are the first reported data in international literature on reference values for lung subdivisions in Chinese children and adolescents...
  4. ncbi request reprint Reference values of diffusing capacity of non-smoking Chinese in Hong Kong
    Mary S M Ip
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong, China
    Respirology 12:599-606. 2007
    ..This study was conducted to define normal reference values and lower limits of normal (LLN) for single-breath carbon monoxide diffusing capacity (DLco) and DLco per unit of alveolar volume (Kco) for Chinese adults in Hong Kong...
  5. ncbi request reprint Updated spirometric reference values for adult Chinese in Hong Kong and implications on clinical utilization
    Mary Sau Man Ip
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China
    Chest 129:384-92. 2006
    ..The aim of the study was to establish updated prediction formulae of spirometric parameters for Hong Kong Chinese and to compare the reference values with those derived from other studies in white and Chinese subjects...
  6. ncbi request reprint A community study of sleep-disordered breathing in middle-aged Chinese women in Hong Kong: prevalence and gender differences
    Mary S M Ip
    Departments of Medicine, The University of Hong Kong, Hong Kong, SAR, China
    Chest 125:127-34. 2004
    ..To investigate the prevalence of sleep-disordered breathing (SDB) and obstructive sleep apnea syndrome (OSAS) in community-based, middle-aged Chinese women, and to compare the differences between gender with a similar study in men...
  7. ncbi request reprint Endothelial function in obstructive sleep apnea and response to treatment
    Mary S M Ip
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
    Am J Respir Crit Care Med 169:348-53. 2004
    ..02) and were similar to baseline values. Our findings demonstrated that men with moderate/severe OSA have endothelial dysfunction and treatment with nCPAP could reverse the dysfunction; the effect, however, was dependent on ongoing use...
  8. ncbi request reprint Obstructive sleep apnea is independently associated with insulin resistance
    Mary S M Ip
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong S A R, PR China
    Am J Respir Crit Care Med 165:670-6. 2002
    ..Our findings suggest that OSA is independently associated with insulin resistance, and its role in the atherogenic potential of sleep disordered breathing is worthy of further exploration...
  9. ncbi request reprint A community study of sleep-disordered breathing in middle-aged Chinese men in Hong Kong
    M S Ip
    Department of Medicine, The University of Hong Kong, Hong Kong, SAR, China
    Chest 119:62-9. 2001
    ..Sleep-disordered breathing (SDB) in Asian populations is being increasingly recognized. This study investigated the prevalence of SDB in Chinese middle-aged office-based male workers in Hong Kong...
  10. ncbi request reprint Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by nasal continuous positive airway pressure
    M S Ip
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
    Am J Respir Crit Care Med 162:2166-71. 2000
    ..The findings offer support for nitric oxide being one of the mediators involved in the acute hemodynamic regulation and long-term vascular remodeling in OSA...
  11. ncbi request reprint Serum leptin and vascular risk factors in obstructive sleep apnea
    M S Ip
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
    Chest 118:580-6. 2000
    ..To define the metabolic profile relevant to vascular risks in obstructive sleep apnea (OSA) and the role of leptin resistance in this risk profile...
  12. ncbi request reprint Obstructive sleep apnea and the metabolic syndrome in community-based Chinese adults in Hong Kong
    Jamie C M Lam
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, SAR, China
    Respir Med 100:980-7. 2006
    ..To investigate the relationship between obstructive sleep apnea (OSA) and the metabolic syndrome, an established cardiovascular risk factor, in middle-aged Chinese subjects...
  13. ncbi request reprint Variability of the prevalence of undiagnosed airflow obstruction in smokers using different diagnostic criteria
    Arthur Chun Wing Lau
    Department of Intensive Care, The University of Hong Kong, Queen Mary Hospital Pokfulam, Hong Kong SAR, China
    Chest 133:42-8. 2008
    ..To estimate the prevalence of undiagnosed airflow obstruction (AFO) in Hong Kong smokers with no previous diagnosis of respiratory disease, and to assess its variability when applying different prediction equations and diagnostic criteria...
  14. ncbi request reprint Antioxidant enzyme activities in healthy Chinese adults: influence of age, gender and smoking
    Siu P Ho
    Division of Respiratory and Critical Care Medicine, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China
    Respirology 10:305-9. 2005
    ..e. catalase (CAT), superoxide dismutase (SOD) and glutathione peroxidase (GPx)) in erythrocytes from a group of healthy Chinese subjects and to study the influence of age, gender and smoking habits on the enzyme activities...
  15. ncbi request reprint Manganese superoxide dismutase and catalase genetic polymorphisms, activity levels, and lung cancer risk in Chinese in Hong Kong
    James C Ho
    University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
    J Thorac Oncol 1:648-53. 2006
    ..We investigated the risk of lung cancer development with respect to manganese superoxide dismutase (MnSOD) and catalase genetic polymorphisms and their association with erythrocyte antioxidant activities...
  16. doi request reprint Shed syndecan-1 restricts neutrophil elastase from alpha1-antitrypsin in neutrophilic airway inflammation
    Stanley C H Chan
    Department of Biochemistry, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China
    Am J Respir Cell Mol Biol 41:620-8. 2009
    ..We conclude that the HS moiety of shed Syn-1 binds and restricts NE from inhibition by alpha(1)-AT...
  17. ncbi request reprint Sleep & the metabolic syndrome
    Jamie C M Lam
    Division of Respiratory Medicine, University Department of Medicine, Queen Mary Hospital The University of Hong Kong, SAR, China
    Indian J Med Res 131:206-16. 2010
    ..This article reviews the current knowledge of the relationship between sleep disturbances, sleep-disordered breathing and the metabolic syndrome in adults...
  18. doi request reprint Determinants of daytime blood pressure in relation to obstructive sleep apnea in men
    Jamie C M Lam
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam, Hong Kong SAR, China
    Lung 187:291-8. 2009
    ....
  19. ncbi request reprint Polymorphisms in the IL-4, IL-4 receptor alpha chain, TNF-alpha, and lymphotoxin-alpha genes and risk of asthma in Hong Kong Chinese adults
    Judith C W Mak
    Division of Respiratory Medicine, Department of Medicine, The University of Hong Kong, Hong Kong, SAR, China
    Int Arch Allergy Immunol 144:114-22. 2007
    ..We aimed to investigate the association of the polymorphisms for IL-4 (C-589T), IL-4R alpha (Gln576Arg), TNF-alpha (G-308A) and LT-alpha (A252G) genes as candidates and asthma in adult Hong Kong Chinese population...
  20. ncbi request reprint An update on obstructive sleep apnea and the metabolic syndrome
    Jamie C M Lam
    University Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Curr Opin Pulm Med 13:484-9. 2007
    ..We review recent data on the relationship between obstructive sleep apnea and metabolic syndrome or its components, including abdominal obesity, insulin resistance, hypertension, and dyslipidemia...
  21. doi request reprint The burden of lung disease in Hong Kong: a report from the Hong Kong Thoracic Society
    Moira Chan-Yeung
    Department of Medicine, Respiratory Division, The University of Hong Kong, Hong Kong, China
    Respirology 13:S133-65. 2008
    ..The burden of lung disease in Hong Kong is not known. This study determined the mortality and hospitalization rates of respiratory diseases in Hong Kong in 2005, their trend in the past decade and their incidence/prevalence...
  22. doi request reprint Disorders of glucose metabolism in sleep-disordered breathing
    Macy M S Lui
    Division of Respiratory Medicine and Critical Care Medicine, Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Hong Kong Special Administrative Region, Hong Kong, People s Republic of China
    Clin Chest Med 31:271-85. 2010
    ..In the biologic system of the human body, all these interact to culminate in clinically relevant outcomes...
  23. doi request reprint Sputum cytology examination followed by autofluorescence bronchoscopy: a practical way of identifying early stage lung cancer in central airway
    Bing Lam
    University Department of Medicine, University of Hong Kong, China
    Lung Cancer 64:289-94. 2009
    ..We hypothesize that by using sputum cytology as the first screening method followed by autofluorescence bronchoscopy could detect early stage lung cancer in the central airway...
  24. ncbi request reprint Implantation of a breathing pacemaker in a tetraplegic patient in Hong Kong
    Jamie C M Lam
    University Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong
    Hong Kong Med J 15:230-3. 2009
    ..Its use facilitates ambulation and improves the quality of life of tetraplegic individuals with chronic ventilatory failure...
  25. doi request reprint Elevated plasma TGF-beta1 levels in patients with chronic obstructive pulmonary disease
    Judith C W Mak
    Division of Respiratory and Critical Care Medicine, Department of Medicine, The University of Hong Kong, Hong Kong SAR, China
    Respir Med 103:1083-9. 2009
    ..We determined plasma TGF-beta(1) levels in patients with COPD and explored its association with common functional polymorphisms of TGF-beta(1) gene at C-509T and T869C in the development of COPD in a case-control study...
  26. ncbi request reprint Analysis of TGF-beta(1) gene polymorphisms in Hong Kong Chinese patients with asthma
    Judith C W Mak
    Division of Respiratory Medicine, Department of Medicine, University of Hong Kong, Hong Kong SAR, China
    J Allergy Clin Immunol 117:92-6. 2006
    ..The C-509T polymorphism of TGF-beta(1) gene has been associated with asthma and atopy in white populations...
  27. ncbi request reprint HDL dysfunction in obstructive sleep apnea
    Kathryn C B Tan
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, PR China
    Atherosclerosis 184:377-82. 2006
    ..HDL dysfunction has been reported in patients with coronary heart disease and we hypothesize that HDL may also be dysfunctional in obstructive sleep apnea (OSA), a condition associated with increased oxidative stress...
  28. ncbi request reprint Silicosis in 76 men: qualitative and quantitative CT evaluation--clinical-radiologic correlation study
    Gaik C Ooi
    School of Professional and Continuing Education, Department of Radiology, University of Hong Kong, Queen Mary Hosp, F 4, Block K, Pokfulam, Hong Kong SAR, China
    Radiology 228:816-25. 2003
    ..To use qualitative and quantitative computed tomography (CT) to test the hypothesis that impaired lung function with silicosis is due to progressive massive fibrosis (PMF) and associated emphysema...
  29. ncbi request reprint Sputum sol neutrophil elastase activity in bronchiectasis: differential modulation by syndecan-1
    Stanley C H Chan
    Department of Biochemistry, University of Hong Kong, 21 Sassoon Road, Hong Kong, China
    Am J Respir Crit Care Med 168:192-8. 2003
    ..Taken together, the results bring a new focus to heparan sulfate/syndecan-1 complexed with neutrophil elastase in inflamed bronchial secretions as a target for modulating elastase susceptibility to physiological antielastases...
  30. ncbi request reprint Advanced glycation endproducts in nondiabetic patients with obstructive sleep apnea
    Kathryn C B Tan
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Sleep 29:329-33. 2006
    ..We hypothesize that AGE concentrations may be increased in subjects with obstructive sleep apnea (OSA), a condition associated with increased oxidative stress...
  31. ncbi request reprint Computed tomographic evaluation of the role of craniofacial and upper airway morphology in obstructive sleep apnea in Chinese
    Bing Lam
    University Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Porfulam, Hong Kong SAR, China
    Respir Med 98:301-7. 2004
    ..To evaluate the relationship between cephalometric parameters, upper airway morphological factors and obstructive sleep apnea (OSA) in Chinese subjects...
  32. ncbi request reprint Alleviation of sleep apnea in patients with chronic renal failure by nocturnal cycler-assisted peritoneal dialysis compared with conventional continuous ambulatory peritoneal dialysis
    Sydney C W Tang
    Department of Medicine, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China
    J Am Soc Nephrol 17:2607-16. 2006
    ..These findings suggest that NPD may have a therapeutic edge over CAPD in sleep apnea that is associated with renal failure as a result of better fluid clearance during sleep...
  33. ncbi request reprint Elevated levels of transforming growth factor-beta(1) in serum of patients with stable bronchiectasis
    Judith C W Mak
    Division of Respiratory and Critical Care Medicine, Department of Medicine, The University of Hong Kong, Administration Block, Queen Mary Hospital, Hong Kong SAR, China
    Respir Med 99:1223-8. 2005
    ..Further studies on the potential mechanisms and pathogenesis implications of this elevation should also be pursued in future...
  34. doi request reprint Sleep apnea is a novel risk predictor of cardiovascular morbidity and death in patients receiving peritoneal dialysis
    Sydney C W Tang
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Kidney Int 77:1031-8. 2010
    ..Thus, sleep apnea syndrome, detected at the start of peritoneal dialysis, is a novel risk predictor for subsequent mortality and cardiovascular events...
  35. ncbi request reprint A Chinese version of the Sleep Apnea Quality of Life Index was evaluated for reliability, validity, and responsiveness
    Wendy Y W Mok
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Pokfulam, Hong Kong SAR, China
    J Clin Epidemiol 57:470-8. 2004
    ..Obstructive sleep apnea (OSA) is a common disorder in many ethnic populations. Patients with OSA have impaired health-related quality of life (HRQOL). No sleep apnea-specific HRQOL measure has been validated in Chinese patients...
  36. pmc Improvement in sleep apnea during nocturnal peritoneal dialysis is associated with reduced airway congestion and better uremic clearance
    Sydney C W Tang
    Division of Nephrology, Department of Medicine, The University of Hong Kong and Queen Mary Hospital, Hong Kong, China
    Clin J Am Soc Nephrol 4:410-8. 2009
    ..Among peritoneal dialysis (PD) patients, nocturnal PD (NPD) is known to improve sleep apnea compared with continuous ambulatory peritoneal dialysis (CAPD), but the contributing factors are unclear...
  37. ncbi request reprint Current perspectives on medical education in China
    Tai Pong Lam
    Family Medicine Unit, Department of Medicine, University of Hong Kong, Apleichau, Hong Kong, China
    Med Educ 40:940-9. 2006
    ..China has a long tradition of education and medicine. However, limited economic conditions and a huge population mean that further development of medical education in China must be tailored to meet the country's needs...
  38. ncbi request reprint In vitro study of regulation of IL-6 production in bronchiectasis
    James C Ho
    Division of Respiratory and Critical Care Medicine, University Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong SAR, China
    Respir Med 98:334-41. 2004
    ..The suppressive effects observed with ibuprofen, triptolide and MK-663 warrant further study...
  39. doi request reprint Chinese green tea ameliorates lung injury in cigarette smoke-exposed rats
    Ka H Chan
    Department of Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
    Respir Med 103:1746-54. 2009
    ....
  40. ncbi request reprint Systemic oxidative and antioxidative status in Chinese patients with asthma
    Judith C W Mak
    Department of Medicine, Division of Respiratory and Critical Care Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, China
    J Allergy Clin Immunol 114:260-4. 2004
    ..Patients with asthma generate an increased amount of reactive oxygen species from peripheral blood cells. Reactive oxygen species produce many of the pathophysiologic changes associated with asthma and may contribute to its pathogenesis...
  41. ncbi request reprint Psychological responses to the SARS outbreak in healthcare students in Hong Kong
    Josephine G W S Wong
    Department of Psychiatry, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Med Teach 26:657-9. 2004
    ..Suitable psychological and occupational support services should be made available in case of future outbreaks...
  42. ncbi request reprint Upregulation of ICAM-1 expression in bronchial epithelial cells by airway secretions in bronchiectasis
    Stanley C H Chan
    Department of Biochemistry, Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
    Respir Med 102:287-98. 2008
    ..The success of drug attenuation of this upregulation provides insight into possible therapeutic paradigms in the management of the disease...
  43. pmc Randomised study of three non-surgical treatments in mild to moderate obstructive sleep apnoea
    Bing Lam
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
    Thorax 62:354-9. 2007
    ..Patients with mild to moderate obstructive sleep apnoea (OSA) may be managed with different treatment options. This study compared the effectiveness of three commonly used non-surgical treatment modalities...