Zhi Yong Han


Affiliation: University of Science and Technology of China
Country: China


  1. Su Y, Li Y, Chen Y, Han Z. Ir/PTC cooperatively catalyzed asymmetric umpolung allylation of α-imino ester enabled synthesis of α-quaternary amino acid derivatives bearing two vicinal stereocenters. Chem Commun (Camb). 2017;53:1985-1988 pubmed publisher
    ..The reaction features good yields, high diastereo- and enantio-selectivities, ease of scale-up to gram scale and further transformation of the products (e.g. to quaternary proline analogues with multi stereocenters). ..
  2. Adili A, Tao Z, Chen D, Han Z. Quinine-catalyzed highly enantioselective cycloannulation of o-quinone methides with malononitrile. Org Biomol Chem. 2015;13:2247-50 pubmed publisher
    ..Moreover, this reaction can be performed in up to 6 mmol scale without any noticeable loss of yield and stereoselectivity. ..