Research Topics
| S S ChiuSummaryAffiliation: University of Hong Kong Country: China Publications
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Detail Information
Publications
Influenza A infection is an important cause of febrile seizuresS S Chiu
Department of Pediatrics, University of Hong Kong, Hong Kong SAR, China
Pediatrics 108:E63. 2001....
The population based socioeconomic burden of pediatric influenza-associated hospitalization in Hong KongSusan S Chiu
Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong Special Administrative Region
Vaccine 30:1895-900. 2012....
Is respiratory viral infection really an important trigger of asthma exacerbations in children?So Lun Lee
Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, SAR, China
Eur J Pediatr 170:1317-24. 2011....- Age-matched comparison of children hospitalized for 2009 pandemic H1N1 influenza with those hospitalized for seasonal H1N1 and H3N2Susan S Chiu
Department of Paediatrics and Adolescent Medicine, The University of Hong Kong, Pokfulam, Hong Kong
PLoS ONE 6:e21837. 2011..There was no difference in other aspects of the clinical course or outcome. CONCLUSION: Disease manifestation of children hospitalized for pH1N1 infection was mild in our patient population... - Immunogenicity and safety of intradermal influenza immunization at a reduced dose in healthy childrenSusan S Chiu
Department of Pediatrics and Adolescent Medicine, University of Hong Kong, Hong Kong, China
Pediatrics 119:1076-82. 2007..We conducted this study to test the hypothesis that intradermal influenza vaccination at one fifth of a standard dose elicits comparable immunogenicity to full-dose intramuscular vaccination in children... - Review of the Varilrix varicella vaccineSusan S Chiu
Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong SAR, China
Expert Rev Vaccines 4:629-43. 2005..Similar to the other Oka-strain vaccines, Varilrix is safe, immunogenic and efficacious in both immunocompromised and immunocompetent children and adults... - Risk-stratified seroprevalence of SARS coronavirus in children residing in a district with point-source outbreak compared to a low-risk areaP P W Lee
Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam, Hong Kong
Hong Kong Med J 14:17-20. 2008..1. SARS coronavirus has low transmissibility at the community level. 2. Subclinical SARS coronavirus infection is rare in children... - Excess mortality associated with the 2009 pandemic of influenza A(H1N1) in Hong KongL Yang
Department of Community Medicine, School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China
Epidemiol Infect 140:1542-50. 2012..The estimates of excess deaths were more than twofold higher than the reported fatal cases with laboratory-confirmed pH1N1 infection... - Nasopharyngeal carriage of antimicrobial-resistant Streptococcus pneumoniae among young children attending 79 kindergartens and day care centers in Hong KongS S Chiu
Department of Pediatrics, University of Hong Kong, Special Administrative Region, Hong Kong, People's Republic of China
Antimicrob Agents Chemother 45:2765-70. 2001..004; odds ratio, 2; 95% confidence interval, 1.2 to 3.2). This study demonstrated the high prevalence of antibiotic-resistant S. pneumoniae in healthy young children in the community in Hong Kong... - Clinical outcomes of bacteremic pneumococcal infections in an area with high resistanceP L Ho
Centre of Infection and Department of Microbiology, Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Pokfulam, Hong Kong Special Administrative Region, People s Republic of China
Eur J Clin Microbiol Infect Dis 25:323-7. 2006..2, p<0.001) and discordant therapy (OR 4.3, 95%CI 1.7-10.9, p<0.002) involving agents with poor anti-pneumococcal activity (but not penicillins and broad-spectrum beta-lactam agents) were significantly associated with mortality... - Decreased levofloxacin susceptibility in Haemophilus influenzae in children, Hong KongPak Leung Ho
Division of Infectious Diseases, Department of Microbiology and Centre of Infection, University of Hong Kong, Hong Kong Special Administrative Region, China
Emerg Infect Dis 10:1960-2. 2004..9%) had decreased susceptibility to quinolones. The five strains had a Ser-84-Lys or Asp-88-Asn substitution in GyrA. Pulsed-field gel electrophoresis showed that the isolates are genetically diverse... - Serotype distribution and antimicrobial resistance patterns of nasopharyngeal and invasive Streptococcus pneumoniae isolates in Hong Kong childrenPak Leung Ho
Division of Infectious Diseases, Department of Microbiology, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Pokfulam, Hong Kong Special Administrative Region, PR China
Vaccine 22:3334-9. 2004..7 and 66.1% of the invasive and carriage isolates, respectively. The same seven serotypes comprised 87.5% invasive isolates and 82.8% carriage isolates with resistance to penicillin, erythromycin and/or cefotaxime... - DNA typing of cytological samples for retrospective identification of an early case of Panton-Valentine leucocidin-positive, community-associated methicillin-resistant Staphylococcus aureus pneumoniaP L Ho
Departments of Microbiology, Paediatrics and Adolescent Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong Special Administrative Region, China
J Clin Microbiol 46:2457-8. 2008..Stored cytological materials prepared from the pleural fluid were retrieved for molecular analysis. The result indicates the presence of a Panton-Valentine leucocidin-positive, spa type 019 MRSA... - Cytotoxic T lymphocytes established by seasonal human influenza cross-react against 2009 pandemic H1N1 influenza virusWenwei Tu
Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Room L7 58, 7 F Laboratory Block, Faculty of Medicine Building, 21 Sassoon Road, Hong Kong
J Virol 84:6527-35. 2010.... - Pediatric hospitalization for pneumococcal diseases preventable by 7-valent pneumococcal conjugate vaccine in Hong KongPak Leung Ho
Department of Microbiology, Queen Mary Hospital, University of Hong Kong, Pokfulam Road, Pokfulam, Hong Kong, SAR, China
Vaccine 25:6837-41. 2007..3 (95% CI, 16.7-21.9) for IPD, 58.5 (95% CI, 57.3-59.6) for clinical pneumonia and 40.6 (95% CI, 59-82.2) for radiological pneumonia... - Fluoroquinolone and other antimicrobial resistance in invasive pneumococci, Hong Kong, 1995-2001Pak Leung Ho
Department of Microbiology, Queen Mary Hospital, The University of Hong Kong, Hong Kong Special Administrative Region, China
Emerg Infect Dis 10:1250-7. 2004..5% from children < or = 5 years of age and 93% from persons of all ages were of serotypes that are included in the 23-valent polysaccharide vaccine... - The prevalence and characteristics of Streptococcus pneumoniae isolates expressing serotypes 6C and 6D in Hong Kong prior to the introduction of the 7-valent pneumococcal conjugate vaccinePak Leung Ho
Department of Microbiology, The University of Hong Kong, Pokfulam Road, Pokfulam, Hong Kong SAR, China
Diagn Microbiol Infect Dis 68:439-44. 2010..Nonetheless, results from the molecular studies indicated that the evolution of the capsular genes have involved complex pathways... - Invasive pneumococcal disease burden in Hong Kong childrenPak Leung Ho
University of Hong Kong, SAR, China
Pediatr Infect Dis J 25:454-5. 2006..9-23.3) for children aged <or=2 years, 15.6 (95% CI, 12.8-18.6) for children aged <or=5 years and 1 (95% CI, 0.52-1.7) for children aged 6-14 years. The findings indicate a significant disease burden... - Universal antenatal human immunodeficiency virus testing in Hong Kong: consensus statementP L Ho
Consensus Meeting Group on Universal Antenatal HIV Testing, Center of Infection, Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong
Hong Kong Med J 7:421-7. 2001..Data from local studies was also presented and discussed. The timing, potential problems, and cost issues involved in testing all pregnant women in Hong Kong for human immunodeficiency virus were then considered... - Immunogenicity and safety of intradermal versus intramuscular route of influenza immunization in infants less than 6 months of age: a randomized controlled trialSusan S Chiu
Department of Pediatric and Adolescent Medicine, The University of Hong Kong, Hong Kong, China
Vaccine 27:4834-9. 2009..We documented maintenance of HAI titers above seroprotective levels against all three vaccine antigens in 97.6% of subjects regardless of vaccination methods over a time of waning maternal antibodies... - Virologically confirmed population-based burden of hospitalization caused by influenza A and B among children in Hong KongSusan S Chiu
Department of Paediatrics and Adolescent Medicine, The University of Hong Kong
Clin Infect Dis 49:1016-21. 2009..We sought to determine the virologically confirmed hospitalization rates associated with influenza virus infection among Hong Kong children... - Comparison of nasopharyngeal flocked swabs and aspirates for rapid diagnosis of respiratory viruses in childrenK H Chan
Department of Microbiology, The University of Hong Kong and Queen Mary Hospital, Hong Kong SAR, China
J Clin Virol 42:65-9. 2008..The quality of clinical specimens is a crucial determinant for virological diagnosis... - Curtailing unnecessary vancomycin usage in a hospital with high rates of methicillin resistant Staphylococcus aureus infectionsC R Kumana
Department of Medicine, The University of Hong Kong, Hong Kong, China
Br J Clin Pharmacol 52:427-32. 2001..aureus isolates (72% from ICU patients) were methicillin resistant... - Rhinovirus infection in hospitalized children in Hong Kong: a prospective studyDaniel K L Cheuk
Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, Hong Kong, China
Pediatr Infect Dis J 26:995-1000. 2007..To analyze the clinical features and estimate the hospitalization disease burden of rhinovirus infection in children in Hong Kong... - Risk-stratified seroprevalence of severe acute respiratory syndrome coronavirus among children in Hong KongPamela P W Lee
Department of Pediatrics and Adolescent Medicine, Queen Mary Hospital, University of Hong Kong, Pokfulam, Hong Kong
Pediatrics 117:e1156-62. 2006..The very low seroprevalence implies little or no population herd immunity to protect against future resurgence of severe acute respiratory syndrome... - Influenza-related hospitalizations among children in Hong KongSusan S Chiu
Department of Pediatrics and Adolescent Medicine, University of Hong Kong, Hong Kong, China
N Engl J Med 347:2097-103. 2002..4 and 8.1 per 10,000 children 10 to 15 years of age. CONCLUSIONS: In the subtropics, influenza is an important cause of hospitalization among children, with rates exceeding those reported for temperate regions... - Human coronavirus NL63 infection and other coronavirus infections in children hospitalized with acute respiratory disease in Hong Kong, ChinaSusan S Chiu
Department of Paediatrics and Adolescent Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
Clin Infect Dis 40:1721-9. 2005..CONCLUSIONS: HCoV-NL63 is a significant pathogen that contributes to the hospitalization of children, and it was estimated to have caused 224 hospital admissions per 100,000 population aged < or = 6 years each year in Hong Kong... - Severe acute respiratory syndrome among childrenChi Wai Leung
Department of Paediatrics and Adolescent Medicine, Princess Margaret Hospital, Lai Chi Kok, Kowloon, Hong Kong
Pediatrics 113:e535-43. 2004.... - Children with respiratory disease associated with metapneumovirus in Hong KongJ S Malik Peiris
The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
Emerg Infect Dis 9:628-33. 2003..Phylogenetically, all HMPV virus strains from Hong Kong belonged to one of the two genetic lineages previously described. HMPV contributed to 441.6 hospital admissions per 100,000 population <6 years of age... - Fecal carriage of CTXM type extended-spectrum beta-lactamase-producing organisms by children and their household contactsWai U Lo
Division of Infectious Diseases, Department of Microbiology and Carol Yu Centre for Infection, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Pokfulam, Hong Kong SAR, China
J Infect 60:286-92. 2010..To investigate the epidemiology of fecal carriage of CTX-M type extended-spectrum beta-lactamases (ESBL)-producing organisms among children and their household contacts...