MCW Chan

Summary

Affiliation: University of Hong Kong
Country: China

Publications

  1. ncbi Systems-level comparison of host responses induced by pandemic and seasonal influenza A H1N1 viruses in primary human type I-like alveolar epithelial cells in vitro
    Suki M Y Lee
    Department of Microbiology, The University of Hong Kong, Hong Kong SAR, PR China
    Respir Res 11:147. 2010
  2. ncbi Influenza H5N1 virus infection of polarized human alveolar epithelial cells and lung microvascular endothelial cells
    Michael C W Chan
    Departments of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, PR China
    Respir Res 10:102. 2009
  3. ncbi Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells
    M C W Chan
    Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong Special Administrative Region of China
    Respir Res 6:135. 2005

Collaborators

  • J M Nicholls
  • S W Tsao
  • Suki M Y Lee
  • Sara S R Kang
  • Cheuk Kin Lo
  • Timothy K W Cheung
  • Malik J S Peiris
  • Robert E W Hancock
  • Renee W Y Chan
  • Alan D L Sihoe
  • Y I Guan
  • Jennifer L Gardy

Detail Information

Publications3

  1. ncbi Systems-level comparison of host responses induced by pandemic and seasonal influenza A H1N1 viruses in primary human type I-like alveolar epithelial cells in vitro
    Suki M Y Lee
    Department of Microbiology, The University of Hong Kong, Hong Kong SAR, PR China
    Respir Res 11:147. 2010
    ..However a comprehensive gene expression profile of pdmH1N1 in relevant primary human cells in vitro has not been reported. Type I alveolar epithelial cells are a key target cell in pdmH1N1 pneumonia...
  2. ncbi Influenza H5N1 virus infection of polarized human alveolar epithelial cells and lung microvascular endothelial cells
    Michael C W Chan
    Departments of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, PR China
    Respir Res 10:102. 2009
    ..These are polarized cells and the polarity of influenza virus entry and egress as well as the secretion of cytokines and chemokines from the virus infected cells are likely to be central to the pathogenesis of human H5N1 disease...
  3. ncbi Proinflammatory cytokine responses induced by influenza A (H5N1) viruses in primary human alveolar and bronchial epithelial cells
    M C W Chan
    Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong Special Administrative Region of China
    Respir Res 6:135. 2005
    ..Since respiratory epithelial cells are the primary target cell for replication of influenza viruses, it is pertinent to investigate the cytokine induction profile of H5N1 viruses in these cells...