Guangshuo Ou


Affiliation: Tsinghua University
Country: China


  1. Feng G, Zhu Z, Li W, Lin Q, Chai Y, Dong M, et al. Hippo kinases maintain polarity during directional cell migration in Caenorhabditis elegans. EMBO J. 2017;36:334-345 pubmed publisher
    ..Therefore, we propose that the Hippo-RhoG feedback regulation maintains cell polarity during directional cell motility. ..
  2. Yang Y, Zhang Y, Li W, Jiang Y, Zhu Z, Hu H, et al. Spectraplakin Induces Positive Feedback between Fusogens and the Actin Cytoskeleton to Promote Cell-Cell Fusion. Dev Cell. 2017;41:107-120.e4 pubmed publisher
  3. Zhang Y, Yang Y, Zhu Z, Ou G. WASP-Arp2/3-dependent actin polymerization influences fusogen localization during cell-cell fusion in Caenorhabditiselegans embryos. Biol Open. 2017;6:1324-1328 pubmed publisher
    ..Thus, the actin cytoskeleton differently promotes cell-cell fusion by regulating fusogen localization to the fusing plasma membrane in larvae or to intracellular vesicles in embryos. ..
  4. Zhu Z, Chai Y, Jiang Y, Li W, Hu H, Li W, et al. Functional Coordination of WAVE and WASP in C. elegans Neuroblast Migration. Dev Cell. 2016;39:224-238 pubmed publisher
  5. Yi P, Li W, Dong M, Ou G. Dynein-Driven Retrograde Intraflagellar Transport Is Triphasic in C. elegans Sensory Cilia. Curr Biol. 2017;27:1448-1461.e7 pubmed publisher
    ..These results reveal the molecular regulation of dynein-2 movement in sensory cilia. ..
  6. Li W, Yi P, Zhu Z, Zhang X, Li W, Ou G. Centriole translocation and degeneration during ciliogenesis in Caenorhabditis elegans neurons. EMBO J. 2017;36:2553-2566 pubmed publisher
    ..Together, our results provide a comprehensive model of ciliogenesis in sensory neurons and reveal the importance of the dynein-dependent centriole translocation in this process. ..