Kehkooi Kee

Summary

Affiliation: Tsinghua University
Country: China

Publications

  1. pmc Human primordial germ cell formation is diminished by exposure to environmental toxicants acting through the AHR signaling pathway
    Kehkooi Kee
    Department of Obstetrics and Gynecology, Center for Human Embryonic Stem Cell Research and Education, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford University, Palo Alto, California, USA
    Toxicol Sci 117:218-24. 2010
  2. pmc Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells
    Sarita Panula
    Department of Obstetrics and Gynecology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94305, USA
    Hum Mol Genet 20:752-62. 2011
  3. pmc LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress
    Ha Nam Nguyen
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA
    Cell Stem Cell 8:267-80. 2011
  4. pmc Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation
    Kehkooi Kee
    Center for Human Embryonic Stem Cell Research and Education, Institute for Stem Cell Biology and Regenerative Medicine, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford University, Palo Alto, California 94305, USA
    Nature 462:222-5. 2009
  5. pmc Theranostic effect of serial manganese-enhanced magnetic resonance imaging of human embryonic stem cell derived teratoma
    Jaehoon Chung
    Department of Medicine, Stanford University, Stanford, California, United States of America
    Magn Reson Med 68:595-9. 2012
  6. doi request reprint Human germ cell lineage differentiation from embryonic stem cells
    Kehkooi Kee
    Center for Human Embryonic Stem Cell Research and Education, Institute for Stem Cell Biology and Regenerative Medicine, Department of Obstetrics and Gynecology, Stanford University, Palo Alto, CA 94304 5542, USA
    CSH Protoc 2008:pdb.prot5048. 2008

Collaborators

  • Outi Hovatta
  • Ha Nam Nguyen
  • Jaehoon Chung
  • Blake Byers
  • Sarita Panula
  • Phillip C Yang
  • Dwight Nishimura
  • Rajesh Dash
  • JoĆ«lle K Barral
  • Hisanori Kosuge
  • Renee A Reijo-Pera
  • Robert C Robbins
  • William Langston
  • Kitchener D Wilson
  • Birgitt Schule
  • Prachi Gujar
  • James Byrne
  • Renee Reijo Pera
  • Jose V Medrano
  • Rosita Bergstrom
  • Ricardo E Dolmetsch
  • Aleksandr Shcheglovitov
  • Theo D Palmer
  • Branden Cord
  • Carlos Simon
  • Joseph C Wu
  • Renee A Reijo Pera

Detail Information

Publications6

  1. pmc Human primordial germ cell formation is diminished by exposure to environmental toxicants acting through the AHR signaling pathway
    Kehkooi Kee
    Department of Obstetrics and Gynecology, Center for Human Embryonic Stem Cell Research and Education, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford University, Palo Alto, California, USA
    Toxicol Sci 117:218-24. 2010
    ..This study demonstrates the utility of hESCs as a model system for direct examination of the molecular and genetic pathways of environmental toxicants on human germ cell development...
  2. pmc Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells
    Sarita Panula
    Department of Obstetrics and Gynecology, Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of Medicine, Stanford University, Palo Alto, CA 94305, USA
    Hum Mol Genet 20:752-62. 2011
    ..This system may provide a useful model for molecular genetic studies of human germline formation and pathology and a novel platform for clinical studies and potential therapeutical applications...
  3. pmc LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress
    Ha Nam Nguyen
    Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA 94305, USA
    Cell Stem Cell 8:267-80. 2011
    ..This enhanced stress sensitivity is consistent with existing understanding of early PD phenotypes and represents a potential therapeutic target...
  4. pmc Human DAZL, DAZ and BOULE genes modulate primordial germ-cell and haploid gamete formation
    Kehkooi Kee
    Center for Human Embryonic Stem Cell Research and Education, Institute for Stem Cell Biology and Regenerative Medicine, Department of Obstetrics and Gynecology, Stanford University School of Medicine, Stanford University, Palo Alto, California 94305, USA
    Nature 462:222-5. 2009
    ..These results are significant to the generation of gametes for future basic science and potential clinical applications...
  5. pmc Theranostic effect of serial manganese-enhanced magnetic resonance imaging of human embryonic stem cell derived teratoma
    Jaehoon Chung
    Department of Medicine, Stanford University, Stanford, California, United States of America
    Magn Reson Med 68:595-9. 2012
    ..Systemic administration of MnCl(2) enabled simultaneous monitoring and elimination of hESC-derived teratoma cells by higher intracellular accumulation of Mn(2+)...
  6. doi request reprint Human germ cell lineage differentiation from embryonic stem cells
    Kehkooi Kee
    Center for Human Embryonic Stem Cell Research and Education, Institute for Stem Cell Biology and Regenerative Medicine, Department of Obstetrics and Gynecology, Stanford University, Palo Alto, CA 94304 5542, USA
    CSH Protoc 2008:pdb.prot5048. 2008
    ..This protocol describes a method to induce germ cell differentiation from hESCs by the addition of BMPs to hESC differentiation medium. The protocol can be used to study the basic mechanism of germ cell development in human cells...