Wei Liu

Summary

Affiliation: Tianjin University of Science and Technology
Country: China

Publications

  1. doi request reprint Synthesis of novel nucleoside analogue phosphorothioamidate prodrugs and in vitro anticancer evaluation against RKO human colon carcinoma cells
    Wei Liu
    College of Sciences, Tianjin University of Science and Technology, Tianjin, China
    Nucleosides Nucleotides Nucleic Acids 32:161-73. 2013
  2. ncbi request reprint Synthesis, modification and docking studies of 5-sulfonyl isatin derivatives as SARS-CoV 3C-like protease inhibitors
    Wei Liu
    College of Sciences, Tianjin University of Science and Technology, Tianjin 300457, China Electronic address
    Bioorg Med Chem 22:292-302. 2014
  3. ncbi request reprint 1,2-Benzisothiazol-3-one derivatives as a novel class of small-molecule caspase-3 inhibitors
    Lixin Wu
    College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China
    Bioorg Med Chem 22:2416-26. 2014
  4. ncbi request reprint [The research progress of Aurora-B kinase and its inhibitors]
    Dan Dan Dong
    College of Sciences, Tianjin University of Science and Technology, Tianjin 300457, China
    Yao Xue Xue Bao 48:457-65. 2013

Collaborators

  • Lin Zhang
  • Lixin Wu
  • Cheng Yang
  • Dan Dan Dong
  • Honggang Zhou
  • Bo Sun
  • Xiaobin Tang
  • Meiqi Lu
  • Zhihui Yan
  • Yan yan Xiao
  • Hong Gang Zhou

Detail Information

Publications4

  1. doi request reprint Synthesis of novel nucleoside analogue phosphorothioamidate prodrugs and in vitro anticancer evaluation against RKO human colon carcinoma cells
    Wei Liu
    College of Sciences, Tianjin University of Science and Technology, Tianjin, China
    Nucleosides Nucleotides Nucleic Acids 32:161-73. 2013
    ....
  2. ncbi request reprint Synthesis, modification and docking studies of 5-sulfonyl isatin derivatives as SARS-CoV 3C-like protease inhibitors
    Wei Liu
    College of Sciences, Tianjin University of Science and Technology, Tianjin 300457, China Electronic address
    Bioorg Med Chem 22:292-302. 2014
    ..Among all compounds, 8k₁ showed most potent inhibitory activity against 3CL(pro) (IC₅₀=1.04 μM). These results indicated that these inhibitors could be potentially developed into anti-SARS drugs...
  3. ncbi request reprint 1,2-Benzisothiazol-3-one derivatives as a novel class of small-molecule caspase-3 inhibitors
    Lixin Wu
    College of Biotechnology, Tianjin University of Science and Technology, Tianjin 300457, China
    Bioorg Med Chem 22:2416-26. 2014
    ..Among the tested compounds, compound 5i exhibited the most potent caspase-3 inhibitory activity (IC50=1.15nM). The molecular docking predicted the interactions and binding modes of the synthesized inhibitor in the caspase-3 active site. ..
  4. ncbi request reprint [The research progress of Aurora-B kinase and its inhibitors]
    Dan Dan Dong
    College of Sciences, Tianjin University of Science and Technology, Tianjin 300457, China
    Yao Xue Xue Bao 48:457-65. 2013
    ..We will focus on recent preclinical and clinical studies that have explored the mechanism of action and clinical effect of Aurora-B inhibitors in cancer treatment...