- FATS is a transcriptional target of p53 and associated with antitumor activityXifeng Zhang
Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
Mol Cancer 9:244. 2010..FATS expression was silent or downregulated in human cancers, and overexpression of FATS suppressed tumorigenicity in vivo independently of p53. Our results reveal FATS as a p53-regulated gene to monitor genomic stability...
- An HDAC1-binding domain within FATS bridges p21 turnover to radiation-induced tumorigenesisZ Li
Department of Biochemistry and Molecular Biology, Key Laboratory of Ministry of Education for Breast Cancer Prevention and Treatment, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
Oncogene 29:2659-71. 2010..Our results reveal a molecular linkage between p21 abundance and radiation-induced carcinogenesis...