Research Topics
| Feng GaoSummaryAffiliation: Tianjin University Country: China Publications
| Collaborators
|
Detail Information
Publications
Three-dimensional scheme for time-domain fluorescence molecular tomography based on Laplace transforms with noise-robust factorsLimin Zhang
College of Precision Instrument and Optoeletronics Engineering, Tianjin University, Tianjin 300072, China
Opt Express 16:7214-23. 2008....
A CT-analogous scheme for time-domain diffuse fluorescence tomographyFeng Gao
College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin, China
J Xray Sci Technol 20:91-105. 2012..A pilot validation of the methodology is performed for two-dimensional scenarios using simulated and experimental data. The results demonstrated the efficacy of the proposed scheme in improving the image quality...- A self-normalized, full time-resolved method for fluorescence diffuse optical tomographyFeng Gao
College of Precision Instrument and Optoeletronics Engineering, Tianjin University, Tianjin 300072, China
Opt Express 16:13104-21. 2008.... - A linear, featured-data scheme for image reconstruction in time-domain fluorescence molecular tomographyFeng Gao
College of Precision Instrument and Optoeletronics Engineering, Tianjin University, Tianjin 300072, China
Opt Express 14:7109-24. 2006.... - Simultaneous fluorescence yield and lifetime tomography from time-resolved transmittances of small-animal-sized phantomFeng Gao
College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
Appl Opt 49:3163-72. 2010.... 
Ori-Finder: a web-based system for finding oriCs in unannotated bacterial genomesFeng Gao
Department of Physics, Tianjin University, Tianjin 300072, China
BMC Bioinformatics 9:79. 2008..Therefore, the increasing availability of genome sequences calls for improved software to identify oriCs in newly sequenced and unannotated bacterial genomes...- DoriC: a database of oriC regions in bacterial genomesFeng Gao
Department of Physics, Tianjin University, Tianjin 300072, China
Bioinformatics 23:1866-7. 2007..AVAILABILITY: DoriC can be accessed from http://tubic.tju.edu.cn/doric/. SUPPLEMENTARY INFORMATION: Supplementary data are available at http://tubic.tju.edu.cn/doric/supplementary.htm... - Towards pH-sensitive imaging of small animals with photon-counting difference diffuse fluorescence tomographyJiao Li
Tianjin University, College of Precision Instruments and Optoelectronics Engineering, Tianjin 300072, China
J Biomed Opt 17:96011-1. 2012.... - Combined hemoglobin and fluorescence diffuse optical tomography for breast tumor diagnosis: a pilot study on time-domain methodologyWei Zhang
College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
Biomed Opt Express 4:331-48. 2013..The results demonstrate the efficacy of improving the accuracy of hemoglobin-DOT based on a priori fluorescence localization... - Time-domain fluorescence-guided diffuse optical tomography based on the third-order simplified harmonics approximationWenjuan Ma
College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin, China
Appl Opt 51:8656-68. 2012.... - Time-resolved diffuse optical tomography and its application to in vitro and in vivo imagingHuijuan Zhao
Tianjin University, State Key Laboratory of Precision Measuring Technology and Instruments, Tianjin 3000072, China
J Biomed Opt 12:062107. 2007..Finally, in vitro and in vivo imaging examples are illustrated for validating the capibility of TR-DOT to provide not only the anatomical but also the physiological information of the objects... - Combined domain-decomposition and matrix-decomposition scheme for large-scale diffuse optical tomographyFang Yang
College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
Appl Opt 49:3111-26. 2010..Also, both numerical simulations and phantom experiments show that MD-based linear inversion is superior to the row-fashioned algebraic reconstruction technique... - Origins of replication in Sorangium cellulosum and Microcystis aeruginosaFeng Gao
Department of Physics, Tianjin University, Tianjin 300072, People s Republic of China
DNA Res 15:169-71. 2008.... - Application of Fourier-wavelet regularized deconvolution for improving image quality of free space propagation x-ray phase contrast imagingZhongxing Zhou
School of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin, People s Republic of China
Phys Med Biol 57:7459-79. 2012.... - GC-Profile: a web-based tool for visualizing and analyzing the variation of GC content in genomic sequencesFeng Gao
Department of Physics, Tianjin University, Tianjin 300072, China
Nucleic Acids Res 34:W686-91. 2006..GC-Profile is freely available at the website http://tubic.tju.edu.cn/GC-Profile/. In addition, precompiled binaries, together with examples and documentation, can also be freely downloaded for a local execution... - Time-resolved diffuse optical tomographic imaging for the provision of both anatomical and functional information about biological tissueHuijuan Zhao
College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
Appl Opt 44:1905-16. 2005.... - Improving visibility of X-ray phase-contrast imaging with Wiener filteringShaorun Gong
College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin, China
J Xray Sci Technol 18:279-92. 2010..9dB. With the trend of the post-filtered experimental contrast to the theoretical one, it could be motivated that higher visibility would be achieved with the introduction of more precise blurring mask and noise spectrum estimation... - Genome sequence of Acinetobacter baumannii MDR-TJFeng Gao
Department of Physics, Tianjin University, Tianjin 300072, China
J Bacteriol 193:2365-6. 2011..The genome sequence of Acinetobacter baumannii strain MDR-TJ was determined by using a combination of 454 pyrosequencing and paired-end sequencing performed with the Roche Genome Sequencer FLX system to generate a scaffolded assembly... - RNA-DNA differences are rarer in proto-oncogenes than in tumor suppressor genesFeng Gao
Department of Physics, Tianjin University, Tianjin 300072, China
Sci Rep 2:245. 2012..e., those cause amino acid changes. A potential mechanism is that, unlike proto-oncogenes, the requirement of tumor suppressor genes to have both alleles affected to cause tumor 'buffers' these genes to tolerate more RDDs... - Spatial-frequency-compression scheme for diffuse optical tomography with dense sampling datasetXiaoqing Zhou
College of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin, China
Appl Opt 52:1779-92. 2013..It takes less than 20 s for the proposed method to experimentally reconstruct one absorption image from a 256×256-sized dataset, which would take a few hours with the conventional method... - DeOri: a database of eukaryotic DNA replication originsFeng Gao
Department of Physics, Tianjin University, Tianjin, China
Bioinformatics 28:1551-2. 2012..AVAILABILITY: Database of Eukaryotic ORIs (DeOri) can be accessed from http://tubic.tju.edu.cn/deori/.. - Techniques to improve the accuracy of noise power spectrum measurements in digital x-ray imaging based on background trends removalZhongxing Zhou
School of Precision Instrument and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
Med Phys 38:1600-10. 2011..The purpose of this study was to investigate an appropriate background detrending technique to improve the accuracy of NPS estimation for digital x-ray systems... - Prediction of replication time zones at single nucleotide resolution in the human genomeFeng Gao
Department of Physics, Tianjin University, Tianjin 300072, China
FEBS Lett 582:2441-4. 2008..1, 6p21.32, 17q11.2 and 22q12.1 nearly all coincide with the determined isochore boundaries. The precise boundaries of the 3198 isochores are available via the website: http://tubic.tju.edu.cn/isomap/... - Near-infrared frequency domain system and fast inverse Monte Carlo algorithm for endoscopic measurement of tubular tissueHuijuan Zhao
College of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin, China
J Xray Sci Technol 19:57-68. 2011..2%. Endoscopic measurement on two tubular solid phantoms were also carried out to evaluate the system and the inversion scheme. The results demonstrated that less than 20% relative error can be achieved... - Functionality of essential genes drives gene strand-bias in bacterial genomesYan Lin
Department of Physics, Tianjin University, Tianjin 300072, China
Biochem Biophys Res Commun 396:472-6. 2010.... - Isochore structures in the chicken genomeFeng Gao
Department of Physics, Tianjin University, China
FEBS J 273:1637-48. 2006..The cumulative GC profile, equipped with the new segmentation algorithm, would be an appropriate starting point for analyzing the isochore structures of higher eukaryotic genomes... - Comparison of various algorithms for recognizing short coding sequences of human genesFeng Gao
Department of Physics, Tianjin University, Tianjin 300072, China
Bioinformatics 20:673-81. 2004..We hope that the Z curve methods presented in this paper would be beneficial to the further development of gene-finding algorithms. AVAILABILITY: The programs of various Z curve methods are available on request... - Complete genome sequence of Acinetobacter baumannii MDR-TJ and insights into its mechanism of antibiotic resistanceHe Huang
Department of Biochemical Engineering, School of Chemical Engineering and Technology, Key Laboratory of Systems Bioengineering, Ministry of Education, Tianjin University, Tianjin 300072, China
J Antimicrob Chemother 67:2825-32. 2012..To determine the genome sequence of Acinetobacter baumannii strain MDR-TJ and characterize the mechanisms of multidrug resistance in this strain... - DoriC 5.0: an updated database of oriC regions in both bacterial and archaeal genomesFeng Gao
Department of Physics, Tianjin University, Tianjin 300072, China
Nucleic Acids Res 41:D90-3. 2013..Consequently, the latest release of DoriC contains oriCs for >1500 bacterial genomes and 81 archaeal genomes, respectively... - Segmentation algorithm for DNA sequencesChun Ting Zhang
Department of Physics, Tianjin University, Tianjin 300072, China
Phys Rev E Stat Nonlin Soft Matter Phys 72:041917. 2005..Particularly, it is much simpler and faster than the entropy-based method. Therefore, the new algorithm is more suitable for analyzing long genome sequences, such as human and other newly sequenced eukaryotic genome sequences... - Comparison of journal self-citation rates between some Chinese and non-Chinese international journalsZu Guo Yang
Library, Tianjin University, Tianjin, China
PLoS ONE 7:e49001. 2012..This study aimed to evaluate these journals by calculating various journal self-citation rates, which are important parameters influencing a journal impact factor... - Tunable add/drop channel coupler based on an acousto-optic tunable filter and a tapered fiberWending Zhang
MOE Key Laboratory of Weak Light Nonlinear Photonics, TEDA Applied Physics School and School of Physics, Nankai University, Tianjin, China
Opt Lett 37:1241-3. 2012..Further possible improvements on the configuration are also discussed... - Optical refocusing three-dimensional wide-field fluorescence lifetime imaging microscopyQiang Wu
The MOE Key Laboratory of Weak Light Nonlinear Photonics, TEDA Applied Physics School and School of Physics, Nankai University, Tianjin, China
Opt Express 20:960-5. 2012..Using a fluorescent microsphere the performance of the system has been tested successfully with respect to three-dimensional fluorescence lifetime microscopy as well as time-resolved fluorescence spectroscopy... - Coronavirus phylogeny based on a geometric approachWen-Xin Zheng
Department of Physics, Tianjin University, Tianjin 300072, China
Mol Phylogenet Evol 36:224-32. 2005..Because the phylogenetic relationships are inferred from the whole genome, instead of some individual genes, the present method represents a new direction of phylogeny study in the post-genome era... - Enzymes are enriched in bacterial essential genesFeng Gao
Department of Physics, Tianjin University, Tianjin, China
PLoS ONE 6:e21683. 2011.... - Total light approach of time-domain fluorescence diffuse optical tomographyAndhi Marjono
Department of Mechanical Engineering and Intelligent Systems, University of Electro Communications, Chofu, Tokyo, Japan
Opt Express 16:15268-85. 2008..The reconstructed images of fluorophore concentration show good quantitativeness and spatial reproducibility. By use of the total light approach, computation is performed much faster than the conventional ones... - Optical tomographic mapping of cerebral haemodynamics by means of time-domain detection: methodology and phantom validationFeng Gao
National Institute of Advanced Industrial Science and Technology, 1 2 Namiki, Tsukuba, Ibaraki, 305 8564, Japan
Phys Med Biol 49:1055-78. 2004..The methodology is also validated by experiments using a solid layered phantom... - Combining sequence and time series expression data to learn transcriptional modulesAnshul Kundaje
Department of Computer Science, Columbia University, New York 10027, USA
IEEE/ACM Trans Comput Biol Bioinform 2:194-202. 2005.... - Imaging of in vitro chicken leg using time-resolved near-infrared optical tomographyHuijuan Zhao
National Institute of Advanced Industrial Science and Technology, Tsukuba, Ibaraki, Japan
Phys Med Biol 47:1979-93. 2002.... - Regulation of cardiac fibroblast cellular function by leukemia inhibitory factorFeng Wang
Winters Center for Heart Failure Research, Baylor College of Medicine, 6565 Fannin Street, Houston, TX 77030, USA
J Mol Cell Cardiol 34:1309-16. 2002..However, the effects of LIF in cardiac fibroblasts are not known. Given that the cardiac fibroblast is the most abundant cell type in the heart, we sought to examine the functional effects of LIF on cardiac fibroblasts in vitro... - Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding dataFeng Gao
Department of Biological Sciences, Columbia University, New York, New York 10027, USA
BMC Bioinformatics 5:31. 2004..The challenge is to extract useful information about the global regulatory network from these data... - Reconstructing clinical events by interpreting NICU monitoring dataFeng Gao
Department of Computing Science, University of Aberdeen
Stud Health Technol Inform 136:879-80. 2008..In this PhD research I investigate techniques to automatically reconstruct clinical events that are not recorded directly but could be reconstructed from continuous physiological data and other discrete data... - Multisite mutations of the PRSS1 gene in a Chinese patient with chronic pancreatitisQi Cai Liu
Department of Laboratory Medicine, First Affiliated Hospital, Fujian Medical University, Fuzhou 350005, China
Hepatobiliary Pancreat Dis Int 7:331-2. 2008..This study was to identify the mutation of the PRSS1 gene in a Chinese patient with chronic pancreatitis and to analyze the clinical features of the disease... - Analysis of partial pol and env sequences indicates a high prevalence of HIV type 1 recombinant strains circulating in GabonIvona Pandrea
Laboratoire de Retroviologie, Centre International de Recherches Medicales, Franceville, Gabon
AIDS Res Hum Retroviruses 18:1103-16. 2002..The main advantage of this approach is that it also allows for evaluation of genotypic susceptibility to antiretroviral drugs without the need for supplementary analyses... - A parametric comparison of diagnostic accuracy with three ordinal diagnostic groupsChengjie Xiong
Division of Biostatistics, Washington University in St Louis, St Louis, MO 63110, USA
Biom J 49:682-93. 2007..Finally, we apply our proposed methodology to a real data set of 118 subjects to compare the diagnostic accuracy of early stage Alzheimer's disease (AD) from multiple neuropsychological tests... - Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statisticsFranco Lombardo
Molecular Properties Group, Pfizer Global Research and Development, Groton Laboratories, Groton, Connecticut 06340, USA
J Med Chem 47:1242-50. 2004..The reduction in the use of animals and the overall faster and cheaper accessibility of the parameters used make this method highly attractive for prospectively predicting the VD of new chemical entities in humans... - Maps of optical differential pathlength factor of human adult forehead, somatosensory motor and occipital regions at multi-wavelengths in NIRHuijuan Zhao
Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology AIST, Tsukuba, Ibaraki, Japan
Phys Med Biol 47:2075-93. 2002..The DPF data will be useful for quantitative monitoring of the haemodynamic changes occurring in adult heads... - Application of functionalized CdS nanoparticles as fluorescence probe in the determination of nucleic acidsLe-yu Wang
College of Chemistry and Materials Science, Anhui Normal University, Wuhu, China
Analyst 127:977-80. 2002..2% for 1 microg mL(-1) calf thymus DNA and 2.4% for 1 microg mL(-1) fish sperm DNA. The method is simple, rapid and sensitive. The recovery and relative standard deviation are very satisfactory... - Determination of enantiomeric excess using the ultraviolet-circular dichroism and the high-performance liquid chromatography-circular dichroism methodsLi Chen
Chemical and Process Engineering Centre, 4 Engineering Drive 4, Block E5, Singapore 117576
Appl Spectrosc 57:797-804. 2003..Compared with the UV-CD method, the results show that excellent results are more readily obtained using the HPLC-CD method. With the systems studied, the latter usually provided outstanding estimations of e.e with low error percentages... - Computational method for muscle-path representation in musculoskeletal modelsFeng Gao
Institute of Mechanical Engineering, Aalborg University, Pontoppidanstraede 101, 9220 Aalborg East, Denmark
Biol Cybern 87:199-210. 2002..Any level of geometric accuracy can be obtained by increasing the number of cross sections and the number of line segments in each cross section. The algorithm is computationally efficient even for large numbers of cross sections... - Estimation of the optimal electrophoretic temperature of DNA single-strand conformation polymorphism by DNA base compositionWei Li
Laboratory of Pediatrics, Medical Scientific Research Center, Guangxi Medical University, China
Electrophoresis 24:2283-9. 2003..T(s) could be estimated by the formula T(s) = [80 x C/(A+1)]/[2.71 + [C/(A+1)]]. T(s) could be increased dramatically by the complementary sequences in both 5'-and 3'-ends of a DNA single-strand... - Repression of allo-cell transplant rejection through CIITA ribonuclease P+ hepatocyteRong Guo
Institute of Hematology, the Union Hospital, Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
World J Gastroenterol 9:1077-81. 2003..This paper studied the effect of Ribonuclease P (RNase P) against CIITA, which was a major regulator of MHCII molecules, on repressing the expression of MHCII molecules on hepatocyte... - Semi-three-dimensional algorithm for time-resolved diffuse optical tomography by use of the generalized pulse spectrum techniqueFeng Gao
Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, 1 2 Namiki, Tsukuba, Ibaraki 305 8564, Japan
Appl Opt 41:7346-58. 2002..We demonstrate our algorithm by comparing it with the calibrated 2-D reconstruction that is in widespread use as a shortcut to 3-D imaging and proving that the semi-3-D algorithm outperforms the calibrated 2-D algorithm... - Optimizing higher throughput methods to assess drug-drug interactions for CYP1A2, CYP2C9, CYP2C19, CYP2D6, rCYP2D6, and CYP3A4 in vitro using a single point IC(50)Feng Gao
Pfizer Global Research and Development, Groton, CT, USA
J Biomol Screen 7:373-82. 2002..In addition, the algorithmic approach we propose would obviously be applicable for other in vitro bioactivity and therapeutic target enzyme and receptor screens... - Retrospective motion correction protocol for high-resolution anatomical MRIPeter Kochunov
Research Imaging Center, University of Texas Health Science Center at San Antonio, Texas, USA
Hum Brain Mapp 27:957-62. 2006..RMC was tested on 35 subjects who were considered at high risk for head motion. Our results show that RMC provided better contrast-to-noise ratio and boundary detail when compared to nonmotion-corrected averaged images... - Chemical gene synthesis: strategies, softwares, error corrections, and applicationsAi Sheng Xiong
Biotechnology Research Institute, Shanghai Academy of Agricultural Sciences, Shanghai, China
FEMS Microbiol Rev 32:522-40. 2008..Also, we will briefly discuss some of the major applications of chemical synthesis of DNA sequences in basic research and applied areas... - The application of BTEM to UV-vis and UV-vis CD spectroscopies: the reaction of Rh4(CO)12 with chiral and achiral ligandsShuying Cheng
Department of Chemical and Bimolecular Engineering, National University of Singapore, 4 Engineering Drive 4, Singapore 117576, Singapore
Talanta 74:1132-40. 2008..The present results indicate that UV-vis and UV-vis-CD spectroscopies can be successfully combined with an appropriate chemometric technique in order to monitor reactive organometallic systems having UV and Vis chromophores... - Identification of unique genetic markers in Rv0927c among Mycobacterium tuberculosis W-Beijing strainsXin Jiang
State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, Shanghai 200433, PR China
Microbes Infect 9:241-6. 2007..Characteristic mutations of Rv0927c that are present in W-Beijing strains can be used as a novel genetic marker for rapid molecular typing of M. tuberculosis W-Beijing strains... - Antigenicity and immunogenicity of HIV-1 consensus subtype B envelope glycoproteinsDenise L Kothe
Department of Microbiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA
Virology 360:218-34. 2007.... - Prediction of proteinase cleavage sites in polyproteins of coronaviruses and its applications in analyzing SARS-CoV genomesFeng Gao
Department of Physics, Tianjin University, 300072, Tianjin, PR China
FEBS Lett 553:451-6. 2003..Compared with known annotations, the performance of the present method is satisfactory. The software ZCURVE_CoV 2.0 is freely available at http://tubic.tju.edu.cn/sars/... - Genetic and neutralization properties of subtype C human immunodeficiency virus type 1 molecular env clones from acute and early heterosexually acquired infections in Southern AfricaMing Li
Department of Surgery, Laboratory for AIDS Vaccine Research and Development, Duke University Medical Center, Durham, NC 27710, USA
J Virol 80:11776-90. 2006..A subset of these gp160 clones are suitable for use as reference reagents to facilitate standardized assessments of vaccine-elicited neutralizing antibody responses... - Cloning of an H+-PPase gene from Thellungiella halophila and its heterologous expression to improve tobacco salt toleranceFeng Gao
School of Life Science, Shandong University, Jinan 250100, PR China
J Exp Bot 57:3259-70. 2006..This result supports the hypothesis that overexpression of H(+)-PPase causes the accumulation of Na(+) in vacuoles instead of in the cytoplasm and avoids the toxicity of excessive Na(+) in plant cells... - MSurvPow: a FORTRAN program to calculate the sample size and power for cluster-randomized clinical trials with survival outcomesFeng Gao
Division of Biostatistics, Washington University School of Medicine, St Louis, MO 63110, USA
Comput Methods Programs Biomed 78:61-7. 2005..In this paper, a user-friendly FORTRAN 90 program was provided to implement this method and a simple example was used to illustrate the features of the program... - DNA interactions of a functionalized ruthenium(II) mixed-polypyridyl complex [Ru(bpy)2ppd]2+Feng Gao
Department of Chemistry, State Key Laboratory of Optoelectronic Materials and Technologies, The Key Laboratory of Gene Enginerring of Ministry of Education, Sun Yat-sen University, Guanghou 510275, PR China
J Inorg Biochem 100:1487-94. 2006..The mechanism studies reveal that singlet oxygen (1O2) and superoxide anion radical (O2*(-))play a significant role in the photocleavage... - Hypoxic postconditioning enhances the survival and inhibits apoptosis of cardiomyocytes following reoxygenation: role of peroxynitrite formationHai-Chang Wang
Department of Cardiology and Department of Physiology, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China
Apoptosis 11:1453-60. 2006.... - Non-parametric estimation for baseline hazards function and covariate effects with time-dependent covariatesFeng Gao
Division of Biostatistics, Washington University School of Medicine, Campus Box 8067, 660 S Euclid Ave, St Louis, MO 63110, USA
Stat Med 26:857-68. 2007..Finally, the performance of the method is evaluated by several simulation studies... - Controlled bimolecular collisions allow sub-diffraction limited microscopy of lipid vesiclesErwen Mei
Department of Chemistry, University of Pennsylvania, Philadelphia, PA 19104, USA
Phys Chem Chem Phys 8:2077-82. 2006..The principle of this method of trajectory time distribution optical microscopy (TTDOM) could be used in a far field optical microscopic system with a resolution of several nanometers... - A hybrid mixture discriminant analysis-random forest computational model for the prediction of volume of distribution of drugs in humanFranco Lombardo
Computational Chemistry and Scientific Computing Groups and Groton Non Clinical Statistics, Pfizer Global Research and Development, Groton Laboratories, Groton, Connecticut 06340, USA
J Med Chem 49:2262-7. 2006..The computational model described can predict human VD(ss) with an accuracy comparable to predictions requiring substantially greater effort and can be applied in place of animal experimentation... - Limb-shaking transient ischemic attack induced by middle cerebral artery stenosisWei-Jian Jiang
Neurovascular Angioplasty Team, Department of Neurology and Neuroradiology, Beijing Tiantan Hospital, Capital University of Medical Sciences, Beijing, China
Cerebrovasc Dis 21:421-2. 2006 - Biochemical and biophysical characterization of the transmissible gastroenteritis coronavirus fusion coreGuangpeng Ma
Department of Preventive Veterinary, College of Veterinary Medicine, Northeast Agriculture University, 150030 Harbin, PR China
Biochem Biophys Res Commun 337:1301-7. 2005.... - Comparison of the proteome of isoniazid-resistant and -susceptible strains of Mycobacterium tuberculosisXin Jiang
State Key Laboratory of Genetic Engineering, Institute of Genetics, School of Life Science, Fudan University, People's Republic of China
Microb Drug Resist 12:231-8. 2006..These results suggest that the differentially expressed proteins from INH-resistant strains might be used as potential immunodiagnosis antigens and candidate novel drug targets against drug-resistant tuberculosis... - Impact of additive noise on system performance of a digital X-ray imaging systemDa Zhang
Center for Bioengineering, School of Electrical and Computer Engineering, University of Oklahoma, Norman, OK 73019, USA
IEEE Trans Biomed Eng 54:69-73. 2007..For example, at an exposure of 20 s, the DQE(O) is approximately 0.22, dropping to 0.11 at 3 lp/mm and to 0.022 at 8 lp/mm... - Synthesis, GC selective DNA binding and topoisomerase II inhibition activities of ruthenium(II) polypyridyl complex containing 11-aminopteridino[6,7-f][1,10]phenanthrolin-13(12H)-oneFeng Gao
MOE Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat Sen University, Guangzhou 510275, PR China
J Inorg Biochem 102:1050-9. 2008..In addition, the complex shows high inhibition activity against topoisomerase II by interfere the DNA religation... - [Analysis of methylation status of the promoter of mdr1 gene in K562 and K562/DNR cells]Feng Gao
Department of Medical Oncology, The First Affiliated Hospital, China Medical University, Shenyang 110001, China
Zhonghua Xue Ye Xue Za Zhi 25:293-5. 2004..CONCLUSION: The methylation patterns of mdr1 gene promotor in K562/DNR and K562 cells were different. mdr1 gene silencing was associated with the promotor methylation... - Centralized immunogens as a vaccine strategy to overcome HIV-1 diversityFeng Gao
The Duke Human Vaccine Institute, Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA
Expert Rev Vaccines 3:S161-8. 2004..It is biologically functional and preserves antigenicity similar to contemporary Env proteins. Most importantly, the group M consensus Env immunogen can elicit both T- and B-cell responses to wild-type HIV-1 isolates... - Heterologous expression of vacuolar H(+)-PPase enhances the electrochemical gradient across the vacuolar membrane and improves tobacco cell salt toleranceXiao Guang Duan
School of Life Science, Shandong University, Jinan, People s Republic of China
Protoplasma 232:87-95. 2007.... - Indexing protein structures using suffix treesFeng Gao
Department of Computer Science, Rensselaer Polytechnic Institute, Troy, NY, USA
Methods Mol Biol 413:147-69. 2008..49 out of 10 proteins from the same superfamily are obtained among the top 10 matches. These results outperform the best previous methods... - A semi-rational design strategy of directed evolution combined with chemical synthesis of DNA sequencesAi Sheng Xiong
Biotechnology Research Institute of Shanghai Academy of Agricultural Sciences, 2901 Beidi Road, Shanghai 201106, China
Biol Chem 388:1291-300. 2007..The purified beta-galactosidase from YH8757 exhibited a lower specific activity at 25 degrees C than those purified from mutated YG6755 and YG8252... - Evaluation of on-line bradycardia boundary detectors from neonatal clinical dataFrancois Portet
Department of Computing Science, University of Aberdeen, King s College, Aberdeen AB24 3UE, UK
Conf Proc IEEE Eng Med Biol Soc 2007:3288-91. 2007..5 to 8.7s vs. STD=35.3 to 19.9s). These methods will be integrated to the BabyTalk project which aims at summarizing neonatal clinical data as text in order to improve data management in Neonatal ICU... - Class I MHC allochimeric presentation of composite immunogenic and self epitopes induces tolerance to genetically diverse rat strainsNatalya V Semiletova
The Dumont UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, 77 120 CHS, Los Angeles, CA 90095 7054, USA
Cell Immunol 248:48-58. 2007.... - Absence of toll-like receptor 4 (TLR4) signaling in the donor organ reduces ischemia and reperfusion injury in a murine liver transplantation modelXiu Da Shen
Dumont University of California, Los Angeles UCLA Transplant Center, Division of Liver and Pancreas Transplantation, Department of Surgery, David Geffen School of Medicine at University of California, Los Angeles UCLA, Los Angeles, CA 90095, USA
Liver Transpl 13:1435-43. 2007..These results provide the rationale to locally modify innate TLR4 signaling in the donor organ to more efficiently control the adaptive posttransplantation IRI-dependent responses... - Targeting topoisomerase II with the chiral DNA-intercalating ruthenium(II) polypyridyl complexesFeng Gao
Key Laboratory of Bioinorganic and Synthetic Chemistry of Ministry of Education, School of Chemistry and Chemical Engineering, Sun Yat Sen University, Guangzhou 510275, People s Republic of China
J Biol Inorg Chem 12:1015-27. 2007..Both complexes show antitumor activity towards HELA, hepG2, BEL-7402, and CNE-1 tumor cells... - Simple strategies for reducing sample loads in in vitro metabolic stability high-throughput screening experiments: a comparison between traditional, two-time-point and pooled sample analysesSabrina X Zhao
Candidate Enhancement Group, Exploratory Medicinal Sciences, Pfizer Inc, Eastern Point Road MS 8118W 102, Groton, Connecticut 06340, USA
J Pharm Sci 94:38-45. 2005..98 and 0.97, respectively. Both methods have the potential to: 1. produce data of similar quality to traditional high throughput ADME assays, 2. be easily implemented, 3. shorten analytical run times, and 4. be reproducible and robust... - Mycobacterial nonhomologous end joining mediates mutagenic repair of chromosomal double-strand DNA breaksNicolas C Stephanou
Immunology Program, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
J Bacteriol 189:5237-46. 2007..These findings demonstrate that prokaryotic NHEJ is specifically required for DSB repair in late stationary phase and can mediate mutagenic repair of homing endonuclease-generated chromosomal DSBs... - Creation of DNA overhangs by using modified DNA overhang cloning methodWei Li
Laboratory of Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi, 530021, People s Republic of China
Appl Microbiol Biotechnol 75:703-9. 2007..The creation of DNA overhangs by using complementary DNA oligonucleotides, T4 ligase, and RNase H is simpler and cheaper than that by using reverse transcriptase and RNase H... - Detection of nucleolar organizer and mitochondrial DNA insertion regions based on the isochore map of Arabidopsis thalianaLing Ling Chen
Laboratory for Computational Biology, Shandong Provincial Research Center for Bioinformatic Engineering and Techniques, Shandong University of Technology, Zibo, China
FEBS J 272:3328-36. 2005..Moreover, the centromeres are located in GC-rich 'isochore-like regions' in all the five chromosomes. The current method can provide a useful tool for analyzing whole genomic sequences of eukaryotes...