Justin Che-Yuen Wu

Summary

Affiliation: The Chinese University of Hong Kong
Country: China

Publications

  1. ncbi request reprint Empirical treatment based on "typical" reflux symptoms is inappropriate in a population with a high prevalence of Helicobacter pylori infection
    Justin C Y Wu
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Gastrointest Endosc 55:461-5. 2002
  2. doi request reprint Chinese herbal medicine (Ma Zi Ren Wan) for functional constipation: study protocol for a prospective, double-blinded, double-dummy, randomized controlled trial
    Linda Ld Zhong
    School of Chinese Medicine, Hong Kong Baptist University, 1 F, Jockey Club School of Chinese Medicine Building, 7 Baptist University Road, Kowloon Tong, Hong Kong, SAR, China
    Trials 14:366. 2013
  3. ncbi request reprint Distinct clinical characteristics between patients with nonerosive reflux disease and those with reflux esophagitis
    Justin C Y Wu
    Institute of Digestive Disease, The Chinese University of Hong Kong, Shatin, Hong Kong
    Clin Gastroenterol Hepatol 5:690-5. 2007
  4. doi request reprint Gastroesophageal reflux disease: an Asian perspective
    Justin C Y Wu
    Institute of Digestive Disease, The Chinese University of Hong Kong, Shatin, Hong Kong
    J Gastroenterol Hepatol 23:1785-93. 2008
  5. doi request reprint Concomitant irritable bowel syndrome is associated with failure of step-down on-demand proton pump inhibitor treatment in patients with gastro-esophageal reflux disease
    J C Y Wu
    Institute of Digestive Disease, The Chinese University of Hong Kong, Shatin, Hong Kong
    Neurogastroenterol Motil 23:155-60, e31. 2011
  6. doi request reprint Community-based study on psychological comorbidity in functional gastrointestinal disorder
    Justin C Y Wu
    Institute of Digestive Disease, Chinese University of Hong Kong, Shatin, Hong Kong
    J Gastroenterol Hepatol 26:23-6. 2011
  7. doi request reprint Does Helicobacter pylori infection protect against esophageal diseases in Asia?
    Justin C Y Wu
    Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China
    Indian J Gastroenterol 30:149-53. 2011
  8. ncbi request reprint Obesity is associated with increased transient lower esophageal sphincter relaxation
    Justin Che Yuen Wu
    Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong
    Gastroenterology 132:883-9. 2007
  9. doi request reprint Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a randomized trial
    Joseph J Y Sung
    Institute of Digestive Disease, Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong
    Ann Intern Med 152:1-9. 2010
  10. doi request reprint Predicting mortality in patients with bleeding peptic ulcers after therapeutic endoscopy
    Philip W Y Chiu
    Department of Surgery, Institute of Digestive Disease, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong
    Clin Gastroenterol Hepatol 7:311-6; quiz 253. 2009

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Empirical treatment based on "typical" reflux symptoms is inappropriate in a population with a high prevalence of Helicobacter pylori infection
    Justin C Y Wu
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Gastrointest Endosc 55:461-5. 2002
    ..The objective of this study was to determine whether diagnosis and empirical treatment based on reflux symptoms alone are appropriate as initial management for patients with gastroesophageal reflux...
  2. doi request reprint Chinese herbal medicine (Ma Zi Ren Wan) for functional constipation: study protocol for a prospective, double-blinded, double-dummy, randomized controlled trial
    Linda Ld Zhong
    School of Chinese Medicine, Hong Kong Baptist University, 1 F, Jockey Club School of Chinese Medicine Building, 7 Baptist University Road, Kowloon Tong, Hong Kong, SAR, China
    Trials 14:366. 2013
    ..In particular, a comparison with conventional western medicine for functional constipation patients is needed...
  3. ncbi request reprint Distinct clinical characteristics between patients with nonerosive reflux disease and those with reflux esophagitis
    Justin C Y Wu
    Institute of Digestive Disease, The Chinese University of Hong Kong, Shatin, Hong Kong
    Clin Gastroenterol Hepatol 5:690-5. 2007
    ..The aim of this study was to compare the clinical characteristics between patients with NERD and those with ERD...
  4. doi request reprint Gastroesophageal reflux disease: an Asian perspective
    Justin C Y Wu
    Institute of Digestive Disease, The Chinese University of Hong Kong, Shatin, Hong Kong
    J Gastroenterol Hepatol 23:1785-93. 2008
    ..Although H. pylori eradication may lead to more resilient GERD in a subset of patients, the benefits of H. pylori eradication outweigh the risks, especially in Asian populations with a high incidence of gastric cancer...
  5. doi request reprint Concomitant irritable bowel syndrome is associated with failure of step-down on-demand proton pump inhibitor treatment in patients with gastro-esophageal reflux disease
    J C Y Wu
    Institute of Digestive Disease, The Chinese University of Hong Kong, Shatin, Hong Kong
    Neurogastroenterol Motil 23:155-60, e31. 2011
    ..We studied the efficacy and predictors for treatment failure of step-down on-demand PPI therapy in patients with non-erosive reflux disease (NERD) and those with low grade erosive esophagitis...
  6. doi request reprint Community-based study on psychological comorbidity in functional gastrointestinal disorder
    Justin C Y Wu
    Institute of Digestive Disease, Chinese University of Hong Kong, Shatin, Hong Kong
    J Gastroenterol Hepatol 26:23-6. 2011
    ..Many of these patients may be reluctant to accept the diagnosis of concomitant psychological disorders and therefore a good doctor-patient rapport and therapeutic relationship are essential for management of these patients...
  7. doi request reprint Does Helicobacter pylori infection protect against esophageal diseases in Asia?
    Justin C Y Wu
    Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong, China
    Indian J Gastroenterol 30:149-53. 2011
    ..The Asian population is probably facing a rising generation with high gastric acid and ghrelin secretion rates. These physiological changes may contribute to increased dietary calorie intake, obesity and increased prevalence of GERD...
  8. ncbi request reprint Obesity is associated with increased transient lower esophageal sphincter relaxation
    Justin Che Yuen Wu
    Institute of Digestive Disease, The Chinese University of Hong Kong, Hong Kong
    Gastroenterology 132:883-9. 2007
    ..We evaluated the association between obesity and function of lower esophageal sphincter (LOS) in subjects without GERD...
  9. doi request reprint Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a randomized trial
    Joseph J Y Sung
    Institute of Digestive Disease, Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong
    Ann Intern Med 152:1-9. 2010
    ..It is uncertain whether aspirin therapy should be continued after endoscopic hemostatic therapy in patients who develop peptic ulcer bleeding while receiving low-dose aspirin...
  10. doi request reprint Predicting mortality in patients with bleeding peptic ulcers after therapeutic endoscopy
    Philip W Y Chiu
    Department of Surgery, Institute of Digestive Disease, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong
    Clin Gastroenterol Hepatol 7:311-6; quiz 253. 2009
    ..Despite advances in management of patients with bleeding peptic ulcers, mortality is still 10%. This study aimed to identify predictive factors and to develop a prediction model for mortality among patients with bleeding peptic ulcers...
  11. pmc Endoscopic clipping versus injection and thermo-coagulation in the treatment of non-variceal upper gastrointestinal bleeding: a meta-analysis
    Joseph J Y Sung
    Department of Medicine and Therapeutics, Prince of Wales Hospital, Shatin, NT, Hong Kong
    Gut 56:1364-73. 2007
    ..Hemoclips, injection therapy and thermocoagulation (heater probe or electrocoagulation) are the most commonly used types of endoscopic hemostasis for the control of non-variceal gastrointestinal bleeding...
  12. ncbi request reprint Omeprazole before endoscopy in patients with gastrointestinal bleeding
    James Y Lau
    Institute of Digestive Disease, Chinese University of Hong Kong, Shatin, Hong Kong, China
    N Engl J Med 356:1631-40. 2007
    ..A neutral gastric pH is critical for the stability of clots over bleeding arteries. We investigated the effect of preemptive infusion of omeprazole before endoscopy on the need for endoscopic therapy...
  13. ncbi request reprint Eradication of Helicobacter pylori and risk of peptic ulcers in patients starting long-term treatment with non-steroidal anti-inflammatory drugs: a randomised trial
    Francis K L Chan
    Departments of Medicine and Therapeutics, The Chinese University of Hong Kong, Special Administrative Region of China, Hong Kong
    Lancet 359:9-13. 2002
    ..We hypothesised that eradication of H pylori infection would reduce the risk of ulcers for patients starting long-term NSAID treatment...
  14. ncbi request reprint Celecoxib versus diclofenac and omeprazole in reducing the risk of recurrent ulcer bleeding in patients with arthritis
    Francis K L Chan
    Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, China
    N Engl J Med 347:2104-10. 2002
    ..We assessed whether celecoxib would be similar to diclofenac plus omeprazole in reducing the risk of recurrent ulcer bleeding in patients at high risk for bleeding...
  15. ncbi request reprint Screening for colorectal cancer in Chinese: comparison of fecal occult blood test, flexible sigmoidoscopy, and colonoscopy
    Joseph J Y Sung
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong
    Gastroenterology 124:608-14. 2003
    ..The aim of this study was to compare the accuracy and safety of these 3 screening procedures in a general population of ethnic Chinese...
  16. ncbi request reprint The effect of endoscopic therapy in patients receiving omeprazole for bleeding ulcers with nonbleeding visible vessels or adherent clots: a randomized comparison
    Joseph J Y Sung
    Endoscopy Center, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong
    Ann Intern Med 139:237-43. 2003
    ..The optimal treatment of ulcers with nonbleeding visible vessels and adherent clots is unclear...
  17. ncbi request reprint Celecoxib versus diclofenac plus omeprazole in high-risk arthritis patients: results of a randomized double-blind trial
    Francis K L Chan
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR
    Gastroenterology 127:1038-43. 2004
    ..We studied the ulcer incidence and factors predicting ulcer recurrence in a prospective, double-blinded trial...
  18. ncbi request reprint Clopidogrel versus aspirin and esomeprazole to prevent recurrent ulcer bleeding
    Francis K L Chan
    Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong, China
    N Engl J Med 352:238-44. 2005
    ..guidelines also recommend clopidrogel for patients who have major gastrointestinal intolerance of aspirin. We compared clopidogrel with aspirin plus esomeprazole for the prevention of recurrent bleeding from ulcers in high-risk patients...
  19. ncbi request reprint Long-term outcome of Helicobacter pylori-negative idiopathic bleeding ulcers: a prospective cohort study
    Lawrence C T Hung
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Gastroenterology 128:1845-50. 2005
    ..Helicobacter pylori-negative idiopathic ulcers are increasingly recognized. The secular trend and long-term outcome of this condition are unknown...
  20. ncbi request reprint Cost-effectiveness of Helicobacter pylori "test and treat" for patients with typical reflux symptoms in a population with a high prevalence of H. pylori infection: a Markov model analysis
    Joyce H S You
    School of Pharmacy, Faculty of Medicine, Centre for Pharmacoeconomics Research, Chinese University of Hong Kong, Hong Kong, China
    Scand J Gastroenterol 41:21-9. 2006
    ..pylori "test and treat" strategy with that of empirical proton-pump inhibitor (PPI) therapy and endoscopy in patients with typical reflux and a high prevalence of H. pylori infection...
  21. ncbi request reprint Helicobacter pylori infection in 1st degree relatives of Chinese gastric cancer patients
    Wai K Leung
    Institute of Digestive Diseases, Shatin, Hong Kong
    Scand J Gastroenterol 41:274-9. 2006
    ..Patterns and risk factors associated with H. pylori infection were investigated in 1st degree relatives of Chinese gastric cancer patients...
  22. ncbi request reprint Initial treatment with lansoprazole in young dyspeptic patients with negative urea breath test result: a randomized controlled trial with 12-month follow-up
    Wai K Leung
    Institute of Digestive Disease, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Am J Gastroenterol 102:1483-8. 2007
    ..We evaluated the long-term effects of an initial 12-wk course of lansoprazole in young dyspeptic patients without Helicobacter pylori (H. pylori) infection...
  23. doi request reprint Upper gastrointestinal tract phenotype of Crohn's disease is associated with early surgery and further hospitalization
    Dorothy K L Chow
    Institute of Digestive Disease, Chinese University of Hong Kong, Department of Medicine and Therapeutics, Prince of Wales Hospital, Hong Kong
    Inflamm Bowel Dis 15:551-7. 2009
    ..We studied the clinical course of CD in Chinese patients presenting with the L4 phenotype and factors predicting its occurrence upon longitudinal follow-up...
  24. doi request reprint Long-term follow-up of ulcerative colitis in the Chinese population
    Dorothy K L Chow
    Department of Medicine and Therapeutics, Institute of Digestive Disease, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, China
    Am J Gastroenterol 104:647-54. 2009
    ..We set out determine the incidence, prevalence, and survival rate of UC in the Chinese population and phenotypic stability by longitudinal follow-up...
  25. ncbi request reprint Magnetic resonance colonography in the detection of colonic neoplasm in high-risk and average-risk individuals
    Wai K Leung
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China
    Am J Gastroenterol 99:102-8. 2004
    ..However, the use of MRC in the detection of colorectal neoplasm in average-risk individuals remains unknown. This study determined the performance and the patient's preference of MRC in the detection of colorectal neoplasm...
  26. ncbi request reprint Treatment of diarrhea-predominant irritable bowel syndrome with traditional Chinese herbal medicine: a randomized placebo-controlled trial
    Wai K Leung
    Institute of Digestive Disease, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong
    Am J Gastroenterol 101:1574-80. 2006
    ..We investigated the therapeutic efficacy of an ancient herbal Chinese formula in patients with diarrhea-predominant IBS...