Samuel Y Wong

Summary

Affiliation: The Chinese University of Hong Kong
Country: China

Publications

  1. pmc Low DHEAS levels are associated with depressive symptoms in elderly Chinese men: results from a large study
    Samuel Y S Wong
    School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China
    Asian J Androl 13:898-902. 2011
  2. pmc Lower urinary tract symptoms (LUTS) as a risk factor for depressive symptoms in elderly men: results from a large prospective study in Southern Chinese men
    Roger Y Chung
    School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China
    PLoS ONE 8:e76017. 2013
  3. pmc Chronic psychosocial stress: does it modulate immunity to the influenza vaccine in Hong Kong Chinese elderly caregivers?
    Samuel Yeung Shan Wong
    The School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, Hong Kong
    Age (Dordr) 35:1479-93. 2013
  4. pmc Patient enablement requires physician empathy: a cross-sectional study of general practice consultations in areas of high and low socioeconomic deprivation in Scotland
    Stewart W Mercer
    General Practice and Primary Care, Institute of Health and Wellbeing, University of Glasgow, 1 Horselethill Road, Glasgow, UK
    BMC Fam Pract 13:6. 2012
  5. pmc Using Chinese version of MYMOP in Chinese medicine evaluation: validity, responsiveness and minimally important change
    Vincent C H Chung
    School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong SAR, China
    Health Qual Life Outcomes 8:111. 2010
  6. pmc Postgraduate education for Chinese medicine practitioners: a Hong Kong perspective
    Vincent C H Chung
    School of Public Health, Chinese University of Hong Kong, Hongkong SAR, PR China
    BMC Med Educ 9:10. 2009
  7. pmc Willingness to accept H1N1 pandemic influenza vaccine: a cross-sectional study of Hong Kong community nurses
    Samuel Y S Wong
    School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, PR China
    BMC Infect Dis 10:316. 2010
  8. pmc Will the community nurse continue to function during H1N1 influenza pandemic: a cross-sectional study of Hong Kong community nurses?
    Eliza L Y Wong
    School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, School of Public Health Building, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
    BMC Health Serv Res 10:107. 2010
  9. pmc The epidemiology and natural history of depressive disorders in Hong Kong's primary care
    Weng Yee Chin
    Department of Family Medicine and Primary Care, The University of Hong Kong, 3 F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong
    BMC Fam Pract 12:129. 2011
  10. pmc The Chinese-version of the CARE measure reliably differentiates between doctors in primary care: a cross-sectional study in Hong Kong
    Stewart W Mercer
    Primary Care Research, General Practice and Primary Care, University of Glasgow, Scotland, UK
    BMC Fam Pract 12:43. 2011

Detail Information

Publications50

  1. pmc Low DHEAS levels are associated with depressive symptoms in elderly Chinese men: results from a large study
    Samuel Y S Wong
    School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China
    Asian J Androl 13:898-902. 2011
    ..Similarly to Western studies, our study shows that DHEA and DHEAS levels are associated with depressive symptoms...
  2. pmc Lower urinary tract symptoms (LUTS) as a risk factor for depressive symptoms in elderly men: results from a large prospective study in Southern Chinese men
    Roger Y Chung
    School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, China
    PLoS ONE 8:e76017. 2013
    ..In elderly men, increased awareness and possible screening are needed to detect the increased risk of clinically relevant depressive symptoms. ..
  3. pmc Chronic psychosocial stress: does it modulate immunity to the influenza vaccine in Hong Kong Chinese elderly caregivers?
    Samuel Yeung Shan Wong
    The School of Public Health and Primary Care, The Chinese University of Hong Kong, Shatin, Hong Kong
    Age (Dordr) 35:1479-93. 2013
    ..Hong Kong Chinese elderly who experience chronic stress have a significantly lower cell-mediated immune response to influenza vaccination when compared with non-caregivers...
  4. pmc Patient enablement requires physician empathy: a cross-sectional study of general practice consultations in areas of high and low socioeconomic deprivation in Scotland
    Stewart W Mercer
    General Practice and Primary Care, Institute of Health and Wellbeing, University of Glasgow, 1 Horselethill Road, Glasgow, UK
    BMC Fam Pract 13:6. 2012
    ..The aim of the study is to assess the factors influencing patient enablement in GP consultations in areas of high and low deprivation...
  5. pmc Using Chinese version of MYMOP in Chinese medicine evaluation: validity, responsiveness and minimally important change
    Vincent C H Chung
    School of Public Health and Primary Care, Chinese University of Hong Kong, Hong Kong SAR, China
    Health Qual Life Outcomes 8:111. 2010
    ..This study aims to adapt MYMOP into Chinese, and to assess its validity, responsiveness and minimally important change values in a sample of patients using Chinese medicine (CM) services...
  6. pmc Postgraduate education for Chinese medicine practitioners: a Hong Kong perspective
    Vincent C H Chung
    School of Public Health, Chinese University of Hong Kong, Hongkong SAR, PR China
    BMC Med Educ 9:10. 2009
    ..In the present study we evaluated TCM graduates' perspectives on their career prospects and their views regarding PGT...
  7. pmc Willingness to accept H1N1 pandemic influenza vaccine: a cross-sectional study of Hong Kong community nurses
    Samuel Y S Wong
    School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, PR China
    BMC Infect Dis 10:316. 2010
    ..Our study aims to assess the willingness of nurses who work for the community nursing service (CNS) in Hong Kong on their acceptance of influenza A (H1N1) influenza vaccination...
  8. pmc Will the community nurse continue to function during H1N1 influenza pandemic: a cross-sectional study of Hong Kong community nurses?
    Eliza L Y Wong
    School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, School of Public Health Building, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
    BMC Health Serv Res 10:107. 2010
    ..The aim of this study was to explore the willingness of community nurses in Hong Kong to work during H1N1 influenza pandemic...
  9. pmc The epidemiology and natural history of depressive disorders in Hong Kong's primary care
    Weng Yee Chin
    Department of Family Medicine and Primary Care, The University of Hong Kong, 3 F Ap Lei Chau Clinic, 161 Main Street, Ap Lei Chau, Hong Kong
    BMC Fam Pract 12:129. 2011
    ..The pathways of care, the long term outcomes and the factors affecting prognosis of these patients requires closer examination...
  10. pmc The Chinese-version of the CARE measure reliably differentiates between doctors in primary care: a cross-sectional study in Hong Kong
    Stewart W Mercer
    Primary Care Research, General Practice and Primary Care, University of Glasgow, Scotland, UK
    BMC Fam Pract 12:43. 2011
    ..The objective of this study was to determine the reliability of the Chinese-version of the CARE Measure in reliably differentiating between doctors in a primary care setting in Hong Kong..
  11. doi Sexual activity, erectile dysfunction and their correlates among 1,566 older Chinese men in Southern China
    Samuel Yeung Shan Wong
    Department of Community and Family Medicine, The Chinese University of Hong Kong, Hong Kong
    J Sex Med 6:74-80. 2009
    ..Few studies on sexuality and its correlates in adults have been conducted in Asia; most studies in Asia have focused instead on erectile dysfunction in men rather than sexuality or sexual activities...
  12. doi The relationship between clinically relevant depressive symptoms and episodes and duration of all cause hospitalization in Southern Chinese elderly
    S Y Wong
    Department of Community and Family Medicine, School of Public Health, The Chinese University of Hong Kong, Hong Kong SAR China
    J Affect Disord 113:272-8. 2009
    ..The objective of this study was to study the effects of having clinically relevant depressive symptoms in community dwelling elderly on all cause hospitalization in the elderly...
  13. pmc The influence of multi-morbidity and self-reported socio-economic standing on the prevalence of depression in an elderly Hong Kong population
    Samuel Y S Wong
    Department of Community and Family Medicine, The Chinese University of Hong Kong, 4 F, School of Public Health, Prince of WalesHospital, Shatin, N T, Hong Kong
    BMC Public Health 8:119. 2008
    ..The aim of the present study was to investigate the relationship between depression, multi-morbidity (number of chronic medical conditions, and measures of socioeconomic standing (SES) in an elderly Hong Kong population...
  14. ncbi The prevalence of Apo E4 genotype and its relationship to bone mineral density in Hong Kong Chinese
    Samuel Yeung Shan Wong
    Department of Community and Family Medicine, School of Public Health, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N T, Hong Kong
    J Bone Miner Metab 23:261-5. 2005
    ..03) were in the opposite direction and thus regarded as false-positive results. It is concluded that the Apo E4 allele is rare in Chinese, and a larger population size is needed to see if Apo E4 is associated with BMD in Chinese...
  15. doi A prospective study on the association between lower urinary tract symptoms (LUTS) and erectile dysfunction: results from a large study in elderly Chinese in Southern China
    Samuel Y S Wong
    Department of Community and Family Medicine, School of Public Health, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N T, Hong Kong
    J Sex Med 6:2024-31. 2009
    ..Aim. The relationship between LUTS and ED is examined using a prospective cohort of 2000 Chinese men...
  16. doi Geographical and household variation in health-related quality of life in Hong Kong
    Samuel Yeung Shan Wong
    Department of Community and Family Medicine, School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, Hong Kong
    Health Place 16:315-20. 2010
    ..This study investigated individual, household, and area effects in the distribution of mental and physical health scores in Hong Kong...
  17. doi Depressive symptoms and lifestyle factors as risk factors of lower urinary tract symptoms in Southern Chinese men: a prospective study
    Samuel Y Wong
    The Chinese University of Hong Kong, Hong Kong
    Aging Male 13:113-9. 2010
    ..Few prospective studies have been conducted to identify risk factors associated with lower urinary tract symptoms (LUTS). Our objective is to evaluate the dietary, lifestyle and medical risk factors of LUTS...
  18. pmc Comparison of primary care experiences among adults in general outpatient clinics and private general practice clinics in Hong Kong
    Samuel Y S Wong
    School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, PR China
    BMC Public Health 10:397. 2010
    ..The objective of the current study was to compare the primary care experiences of GOPC users and the users of care provided by private general practitioners (GPs) in Hong Kong via a territory-wide telephone survey...
  19. pmc Depressive symptoms and change in abdominal obesity in the elderly: positive or negative association?
    Samuel Y S Wong
    School of Public Health and Primary Care, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, China
    Am J Geriatr Psychiatry 19:730-42. 2011
    ..Recent evidence suggests that depression can result in abdominal obesity in the elderly. Few longitudinal studies are available and none has been conducted outside the United States...
  20. doi The relationship between worthlessness and mortality in a large cohort of Chinese elderly men
    Samuel Y Wong
    School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR
    Int Psychogeriatr 23:609-15. 2011
    ..This study explored the relationship between "worthlessness" and all cause non-suicide mortality in Chinese elderly men...
  21. doi Comparing the effectiveness of mindfulness-based stress reduction and multidisciplinary intervention programs for chronic pain: a randomized comparative trial
    Samuel Yeung Shan Wong
    School of Public Health and Primary Care, The Chinese University of Hong Kong
    Clin J Pain 27:724-34. 2011
    ....
  22. pmc A randomized, controlled clinical trial: the effect of mindfulness-based cognitive therapy on generalized anxiety disorder among Chinese community patients: protocol for a randomized trial
    Samuel Y S Wong
    Division of Family Medicine and Primary Health Care, School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, China
    BMC Psychiatry 11:187. 2011
    ..Our objective is to compare the clinical effectiveness of the MBCT program with a psycho-education programme and usual care in reducing anxiety symptoms in people suffering from generalized anxiety disorder...
  23. ncbi Maximum oxygen uptake and body composition of healthy Hong Kong Chinese adult men and women aged 20 - 64 years
    Samuel Yeung Shan Wong
    Department of Community and Family Medicine, School of Public Health, Chinese University of Hong Kong, School of Public Health, Shatin Hospital, Hong Kong
    J Sports Sci 26:295-302. 2008
    ..35 to 0.24 ml kg(-1) min(-1) year(-1) in men and from 0.30 to 0.15 ml kg(-1) min(-1) year(-1) in women. We conclude that age, fat mass, and lean mass are independent determinants of maximal oxygen uptake in Chinese adults...
  24. ncbi Improving general practitioners' interviewing skills in managing patients with depression and anxiety: a randomized controlled clinical trial
    S Y S Wong
    Department of Community and Family Medicine, The Chinese University of, Hong Kong
    Med Teach 29:e175-83. 2007
    ..Studies regarding the effectiveness of CME programmes on physicians' behaviour and communication skills showed inconsistent results. Few randomized controlled trials have been conducted in Asia...
  25. ncbi The association between isoflavone and lower urinary tract symptoms in elderly men
    Samuel Y S Wong
    Department of Community and Family Medicine, School of Public Health, Prince of Wales Hospital, Shatin, N T, Hong Kong
    Br J Nutr 98:1237-42. 2007
    ..68; 95 % CI 0.51, 0.92; 21.8 mg and above: OR 0.73; 95 % CI 0.54, 0.98) after adjustment for covariates. In this cross-sectional study, we showed a strong inverse association between dietary intake of isoflavone and the risk of LUTS...
  26. ncbi Osteoporosis in Chinese patients with anorexia nervosa
    Samuel Wong
    Jockey Club Centre for Osteoporosis Care and Control, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
    Int J Eat Disord 36:104-8. 2004
    ..A case-control study was conducted to determine whether bone mass is reduced in Chinese patients with anorexia nervosa (AN) and to study the risk factors for low bone mass in the same population...
  27. ncbi Is dietary counselling effective in increasing dietary calcium, protein and energy intake in patients with osteoporotic fractures? A randomized controlled clinical trial
    S Y Wong
    Department of Community and Family Medicine, The Chinese University of Hong Kong, Hong Kong
    J Hum Nutr Diet 17:359-64. 2004
    ..Future studies with longer duration and more objective clinical outcomes will be helpful to further demonstrate the long-term effects of dietary intervention on osteoporosis and other chronic diseases...
  28. ncbi Depression and bone mineral density: is there a relationship in elderly Asian men? Results from Mr. Os (Hong Kong)
    Samuel Y S Wong
    4 F, Department of Community and Family Medicine, School of Public Health, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Osteoporos Int 16:610-5. 2005
    ..0 (low bone mass). We conclude that depression is associated with lower BMD; however, to determine whether depression causes lower BMD or vice versa, we will need to await findings from future prospective studies...
  29. ncbi Are we more than the sum of our parts? Should we listen to Albert Einstein?
    Samuel Y S Wong
    Department of Community and Family Medicine, School of Public Health, Prince of Wales Hospital
    Aust Fam Physician 34:291-2. 2005
  30. ncbi Primary care physicians in Hong Kong and Canada--how did their practices differ during the SARS epidemic?
    Samuel Yeung Shan Wong
    Department of Community and Family Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Fam Pract 22:361-6. 2005
    ..Hong Kong and Canada have very different primary health care systems. We thus hypothesized family physicians between the two places would be different in how they protected themselves, their staff and families during the epidemic...
  31. ncbi Bone mineral density and the risk of peripheral arterial disease in men and women: results from Mr. and Ms Os, Hong Kong
    S Y S Wong
    Department of Community and Family Medicine, Chinese University of Hong Kong, Shatin NT, Hong Kong
    Osteoporos Int 16:1933-8. 2005
    ..This indicates that other factors may be contributing to the association between peripheral vascular disease and osteoporosis...
  32. ncbi Depressive symptoms in middle-aged men: results from a household survey in Hong Kong
    Samuel Yeung Shan Wong
    Department of Community and Family Medicine, Chinese University of Hong Kong, 4 F, School of Public Health, Prince of Wales Hospital, Shatin, NT
    J Affect Disord 92:215-20. 2006
    ..To evaluate the prevalence and risk factors of depressive symptoms in middle-aged Chinese men aged 45-64...
  33. ncbi What are the barriers faced by general practitioners in treating depression and anxiety in Hong Kong?
    S Y S Wong
    Department of Community and Family Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Int J Clin Pract 60:437-41. 2006
    ..Having a higher qualification in family medicine may reduce the barriers of having lack of confidence and experience in these physicians...
  34. ncbi Risk of depression in patients with chronic respiratory diseases: results from two large cohort studies in Chinese elderly from Hong Kong
    Samuel Y S Wong
    Department of Community and Family Medicine, School of Public Health, Chinese University of Hong Kong, Hong Kong
    Int J Geriatr Psychiatry 21:233-8. 2006
    ....
  35. pmc Clinically relevant depressive symptoms and peripheral arterial disease in elderly men and women. Results from a large cohort study in Southern China
    Samuel Y S Wong
    Department of Community and Family Medicine, School of Public Health, Chinese University of Hong Kong, Shatin, N T, Hong Kong
    J Psychosom Res 63:471-6. 2007
    ..Results from previous epidemiological studies on the relationship between depression and peripheral arterial diseases (PADs) were mixed. Therefore, a study was conducted to investigate this relationship in a large Chinese elderly sample...
  36. ncbi Prevalence of and risk factors for androgen deficiency in middle-aged men in Hong Kong
    Samuel Yeung Shan Wong
    Department of Community and Family Medicine, School of Public Health, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N T, Hong Kong
    Metabolism 55:1488-94. 2006
    ..Future studies with large sample size are needed to evaluate the risk factors for androgen deficiency in men...
  37. ncbi Depression and lower urinary tract symptoms: Two important correlates of erectile dysfunction in middle-aged men in Hong Kong, China
    Samuel Yeung Shan Wong
    Department of Community and Family Medicine, The Chinese University of Hong Kong, School of Public Health, Prince of Wale Hospital, Shatin, Hong Kong
    Int J Urol 13:1304-10. 2006
    ..To evaluate the correlates of erectile dysfunction (ED) in Hong Kong middle-aged Chinese men aged 45-64 years...
  38. ncbi Lower urinary tract symptoms and depressive symptoms in elderly men
    Samuel Y S Wong
    Department of Community and Family Medicine, The Chinese University of Hong Kong, 4 F, School of Public Health Prince of Wales Hospital Shatin, N T, Hong Kong
    J Affect Disord 96:83-8. 2006
    ..To evaluate the impact of moderate to severe lower urinary tract symptoms (LUTS) on clinically significant depressive symptoms in elderly Chinese men aged 65 and above...
  39. ncbi Risk factors for lower urinary tract symptoms in southern Chinese men
    Samuel Y Wong
    Department of Community and Family Medicine, Chinese University of Hong Kong, Hong Kong, People s Republic of China
    Urology 68:1009-14. 2006
    ..Previous epidemiologic studies evaluating the risk factors for LUTS were mainly conducted in non-Chinese populations...
  40. ncbi Vertebral bone mineral density, marrow perfusion, and fat content in healthy men and men with osteoporosis: dynamic contrast-enhanced MR imaging and MR spectroscopy
    James F Griffith
    Department of Diagnostic Radiology, Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, Hong Kong SAR, China
    Radiology 236:945-51. 2005
    ....
  41. ncbi Bone marrow diffusion in osteoporosis: evaluation with quantitative MR diffusion imaging
    David K W Yeung
    Department of Clinical Oncology, Prince of Wales Hospital, Hong Kong, China
    J Magn Reson Imaging 19:222-8. 2004
    ..To determine the diffusion of vertebral body marrow with quantitative MR diffusion imaging and to examine whether differences exist between subjects with postmenopausal osteoporosis and premenopausal control subjects...
  42. ncbi How to provide an effective primary health care in fighting against severe acute respiratory syndrome: the experiences of two cities
    William C W Wong
    Department of Community and Family Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China PRC
    Am J Infect Control 35:50-5. 2007
    ....
  43. ncbi Vertebral marrow fat content and diffusion and perfusion indexes in women with varying bone density: MR evaluation
    James F Griffith
    Department of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, Hong Kong SAR, China
    Radiology 241:831-8. 2006
    ..To prospectively study the relationship among vertebral marrow fat content, marrow diffusion indexes, and marrow and erector spinae muscle perfusion indexes in female subjects with varying bone mineral density...
  44. ncbi Strengths, weaknesses, and development of Traditional Chinese Medicine in the health system of Hong Kong: through the eyes of future Western doctors
    William C W Wong
    Department of Community and Family Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital Shatin, Hong Kong SAR, People s Republic of China
    J Altern Complement Med 12:185-9; discussion 191-2. 2006
    ..Paralleled with the experience in the United Kingdom and other countries, if traditional and conventional doctors are to work effectively side by side, current medical education and health service arrangements need to change...
  45. doi Referral to and attitude towards traditional Chinese medicine amongst western medical doctors in postcolonial Hong Kong
    Vincent C H Chung
    School of Public Health and Primary Care, Chinese University of Hong Kong, China
    Soc Sci Med 72:247-55. 2011
    ..This implies that effective TCAM policies within WM dominated health systems like Hong Kong would require structural and educational solutions that foster both increased understanding and safe referrals...
  46. pmc Willingness of Hong Kong healthcare workers to accept pre-pandemic influenza vaccination at different WHO alert levels: two questionnaire surveys
    Josette S Y Chor
    School of Public Health and Primary Care, Chinese University of Hong Kong, School of Public Health, Prince of Wales Hospital, Shatin, Hong Kong
    BMJ 339:b3391. 2009
    ..To assess the acceptability of pre-pandemic influenza vaccination among healthcare workers in public hospitals in Hong Kong and the effect of escalation in the World Health Organization's alert level for an influenza pandemic...
  47. ncbi Procedures in primary care dermatology
    Antonio A T Chuh
    Department of Community and Family Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Aust Fam Physician 34:347-51. 2005
    ..General practitioners can provide a range of diagnostic and treatment procedures for patients with dermatological problems...
  48. doi The association between shift duty and abnormal eating behavior among nurses working in a major hospital: a cross-sectional study
    Hidy Wong
    School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Int J Nurs Stud 47:1021-7. 2010
    ..Shift work induces stress, disturbs family life and interrupts regular meal schedules. Few studies have addressed the association between shift duties and abnormal eating behavior among hospital nurses...
  49. ncbi Osteoporosis and transforming growth factor-beta-1 gene polymorphism in Chinese men and women
    Edith Ming Chu Lau
    Department of Family and Community Medicine, Chinese University of Hong Kong, Hong Kong
    J Bone Miner Metab 22:148-52. 2004
    ..This finding could result from different sampling methods between the previous and current studies and environmental factors and ethnic differences between the two populations...
  50. pmc Interfacing between primary and secondary care is needed
    Albert Lee
    BMJ 329:403. 2004