G M Tse

Summary

Affiliation: The Chinese University of Hong Kong
Country: China

Publications

  1. pmc Fine needle aspiration cytology of granulomatous mastitis
    G M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT, Hong Kong, China
    J Clin Pathol 56:519-21. 2003
  2. pmc Fine needle aspiration cytology of the breast: the nonmalignant categories
    Paulo Mendoza
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Patholog Res Int 2011:547580. 2011
  3. pmc Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: possible implications for targeted therapy
    Yvonne Hui Fang Teng
    Department of Pathology, Singapore General Hospital, Outram Road, Singapore 169608, Singapore
    Breast Cancer Res 13:R35. 2011
  4. pmc Breast cancer prognostic classification in the molecular era: the role of histological grade
    Emad A Rakha
    Department of Histopathology, Nottingham City Hospital NHS Trust, Nottingham University, Nottingham, UK
    Breast Cancer Res 12:207. 2010
  5. ncbi request reprint In vivo proton magnetic resonance spectroscopy of breast lesions: an update
    Gary M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong
    Breast Cancer Res Treat 104:249-55. 2007
  6. ncbi request reprint Magnetic resonance imaging of breast lesions--a pathologic correlation
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Ngan Shing Street, Shatin, NT, Hong Kong
    Breast Cancer Res Treat 103:1-10. 2007
  7. pmc The role of immunohistochemistry for smooth-muscle actin, p63, CD10 and cytokeratin 14 in the differential diagnosis of papillary lesions of the breast
    G M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong SAR, China
    J Clin Pathol 60:315-20. 2007
  8. ncbi request reprint p63 is useful in the diagnosis of mammary metaplastic carcinomas
    Gary M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong
    Pathology 38:16-20. 2006
  9. pmc Metaplastic carcinoma of the breast: a clinicopathological review
    G M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong
    J Clin Pathol 59:1079-83. 2006
  10. pmc Stromal nitric oxide synthase (NOS) expression correlates with the grade of mammary phyllodes tumour
    G M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Ngan Shing Street, Shatin, NT, Hong Kong, China
    J Clin Pathol 58:600-4. 2005

Collaborators

Detail Information

Publications93

  1. pmc Fine needle aspiration cytology of granulomatous mastitis
    G M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT, Hong Kong, China
    J Clin Pathol 56:519-21. 2003
    ..The fine needle aspiration cytological (FNAC) features of GM have rarely been discussed in the literature. These features are reported in eight histologically confirmed cases of GM...
  2. pmc Fine needle aspiration cytology of the breast: the nonmalignant categories
    Paulo Mendoza
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Patholog Res Int 2011:547580. 2011
    ..Though false-positive cases are less commonly found, they will also be discussed briefly...
  3. pmc Mutations in the epidermal growth factor receptor (EGFR) gene in triple negative breast cancer: possible implications for targeted therapy
    Yvonne Hui Fang Teng
    Department of Pathology, Singapore General Hospital, Outram Road, Singapore 169608, Singapore
    Breast Cancer Res 13:R35. 2011
    ..However, the rate of EGFR mutations is poorly defined. We, therefore, sought to characterize EGFR mutations in triple negative breast cancers...
  4. pmc Breast cancer prognostic classification in the molecular era: the role of histological grade
    Emad A Rakha
    Department of Histopathology, Nottingham City Hospital NHS Trust, Nottingham University, Nottingham, UK
    Breast Cancer Res 12:207. 2010
    ....
  5. ncbi request reprint In vivo proton magnetic resonance spectroscopy of breast lesions: an update
    Gary M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong
    Breast Cancer Res Treat 104:249-55. 2007
    ..With these improvements, (1)H-MRS may potentially be useful in detection of smaller malignant lesions, characterization of malignant lesions into non-invasive or invasive, and as an invaluable tool in disease progression monitoring...
  6. ncbi request reprint Magnetic resonance imaging of breast lesions--a pathologic correlation
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Ngan Shing Street, Shatin, NT, Hong Kong
    Breast Cancer Res Treat 103:1-10. 2007
    ..These may be related to increased vascular endothelial growth factor mediated increased microvessel density as well as increased permeability, which manifest as increased rapid contrast uptake and dissipation...
  7. pmc The role of immunohistochemistry for smooth-muscle actin, p63, CD10 and cytokeratin 14 in the differential diagnosis of papillary lesions of the breast
    G M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong SAR, China
    J Clin Pathol 60:315-20. 2007
    ..The evaluation of myoepithelial cells can be helpful, with benign papilloma showing a continuous myoepithelial cell layer, which becomes attenuated or absent in malignant papillary lesions...
  8. ncbi request reprint p63 is useful in the diagnosis of mammary metaplastic carcinomas
    Gary M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong
    Pathology 38:16-20. 2006
    ....
  9. pmc Metaplastic carcinoma of the breast: a clinicopathological review
    G M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong
    J Clin Pathol 59:1079-83. 2006
    ..Mammary metaplastic carcinoma encompasses epithelial-only carcinoma (high-grade adenosquamous carcinoma or pure squamous cell carcinoma), biphasic epithelial and sarcomatoid carcinoma and monophasic spindle cell carcinoma...
  10. pmc Stromal nitric oxide synthase (NOS) expression correlates with the grade of mammary phyllodes tumour
    G M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Ngan Shing Street, Shatin, NT, Hong Kong, China
    J Clin Pathol 58:600-4. 2005
    ..In mammary fibroepithelial lesions, NOS expression in stromal cells has been reported to be lower in fibroadenomas than in phyllodes tumours...
  11. pmc Stromal CD10 expression in mammary fibroadenomas and phyllodes tumours
    G M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Ngan Shing Street, Shatin, NT, HKSAR, China
    J Clin Pathol 58:185-9. 2005
    ..In the breast, myoepithelial cells express CD10, but there are few studies of the expression of CD10 in mammary fibroepithelial lesions...
  12. doi request reprint Fine needle aspiration cytology of papillary lesions of the breast: how accurate is the diagnosis?
    G M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong
    J Clin Pathol 61:945-9. 2008
    ..Cytological diagnosis of mammary papillary lesions is difficult...
  13. ncbi request reprint Granulomatous mastitis: a clinicopathological review of 26 cases
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong
    Pathology 36:254-7. 2004
    ..Twenty-six cases of granulomatous mastitis were examined to determine the common histological and clinical features and the possible association with micro-organisms...
  14. ncbi request reprint Increased c-kit (CD117) expression in malignant mammary phyllodes tumors
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong
    Mod Pathol 17:827-31. 2004
    ..This provides strong evidence that c-kit receptor mediated tyrosine kinase involvement in the pathogenesis of phyllodes tumors, and the therapeutic agent, STI571, Glivec, may be a potentially useful drug for its management...
  15. pmc CD44s is useful in the differentiation of benign and malignant papillary lesions of the breast
    G M K Tse
    Department of Anatomical Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Ngan Shing Street, Shatin, NT Hong Kong, SAR
    J Clin Pathol 58:1185-8. 2005
    ..CD44s expression in benign and malignant papillary lesions was evaluated...
  16. ncbi request reprint Neuroendocrine differentiation in pure type mammary mucinous carcinoma is associated with favorable histologic and immunohistochemical parameters
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT, Hong Kong
    Mod Pathol 17:568-72. 2004
    ..Our findings suggest that the identification of neuroendocrine differentiation in pure mucinous carcinoma is associated with more favorable histologic and immunohistochemical parameters...
  17. pmc Endothelin-1 expression correlates with atypical histological features in mammary phyllodes tumours
    Gary M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    J Clin Pathol 60:1051-6. 2007
    ..While the grading of phyllodes tumours depends on a combination of histological parameters, prediction of their behaviour remains difficult...
  18. doi request reprint Correlation of biomarkers in head and neck squamous cell carcinoma
    Gary M Tse
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Otolaryngol Head Neck Surg 143:795-800. 2010
    ....
  19. doi request reprint Diagnosing breast lesions by fine needle aspiration cytology or core biopsy: which is better?
    Gary M Tse
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing Street, Shatin, Hong Kong
    Breast Cancer Res Treat 123:1-8. 2010
    ....
  20. doi request reprint Papillary lesions of the breast--accuracy of core biopsy
    Gary M Tse
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong
    Histopathology 56:481-8. 2010
    ..To assess the accuracy of diagnosing papillary breast lesions in core needle biopsy...
  21. doi request reprint Breast cancer in the elderly: a histological assessment
    Gary M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Ngan Shing Street, Shatin, Hong Kong
    Histopathology 55:441-51. 2009
    ..To understand the correlation between the expression status of different biological markers in breast cancers in the elderly...
  22. doi request reprint HER2 expression predicts improved survival in patients with cervical node-positive head and neck squamous cell carcinoma
    Gary M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
    Otolaryngol Head Neck Surg 141:467-73. 2009
    ..To investigate the prognostic value of HER2 and p63 expression in head and neck squamous cell carcinoma (HNSCC)...
  23. doi request reprint Phyllodes tumor of the breast: an update
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong
    Breast Cancer 17:29-34. 2010
    ..It is foreseeable that more exciting data will be generated to help us to understand the etiology and pathogenesis of phyllodes tumor...
  24. doi request reprint The role of immunohistochemistry in the differential diagnosis of papillary lesions of the breast
    G M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR, China
    J Clin Pathol 62:407-13. 2009
    ..As the experience with these markers remains rather limited, it is too early to recommend basing treatment choices on these marker studies alone. Complete removal of lesion is probably still the treatment of choice...
  25. doi request reprint Fine needle aspiration cytology of breast cancer in women aged 70 years and older
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Ngan Shing Street, Shatin, NT, Hong Kong SAR
    Pathology 40:573-9. 2008
    ..We reviewed the fine needle aspiration cytology (FNAC) to assess the cytological characteristics and any clues to assist in the diagnosis...
  26. ncbi request reprint Increased epidermal growth factor receptor (EGFR) expression in malignant mammary phyllodes tumors
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing Street, Shatin, NT, Hong Kong SAR, China
    Breast Cancer Res Treat 114:441-8. 2009
    ..The results of this study provide strong evidence that EGFR overexpression is involved in the pathogenesis of phyllodes tumors, although gene amplification may not be the major underlying mechanism for overexpression...
  27. ncbi request reprint Strong immunohistochemical expression of vascular endothelial growth factor predicts overall survival in head and neck squamous cell carcinoma
    Gary M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Ngan Shing Street, Shatin, NT, Hong Kong
    Ann Surg Oncol 14:3558-65. 2007
    ....
  28. ncbi request reprint Calcification in breast lesions: pathologists' perspective
    G M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong
    J Clin Pathol 61:145-51. 2008
    ..Furthermore, analysis of the characteristics of the calcifications may help to predict the tumour size and grade, and presence of invasion...
  29. ncbi request reprint Intermediate to highly suspicious calcification in breast lesions: a radio-pathologic correlation
    Gary M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Ngan Shing Street, Shatin, NT, Hong Kong SAR
    Breast Cancer Res Treat 110:1-7. 2008
    ..In a benign biopsy that fails to identify the calcifications visible in the mammography, further evaluation or cutting of the histologic block is recommended to minimize the potential of a false negative investigation...
  30. ncbi request reprint Spindle cell lesions of the breast--the pathologic differential diagnosis
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Ngan Shing Street, Shatin, NT, Hong Kong
    Breast Cancer Res Treat 109:199-207. 2008
    ....
  31. pmc Sputum cytology of patients with severe acute respiratory syndrome (SARS)
    G M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Ngan Shing Street, NT, Hong Kong ROC
    J Clin Pathol 57:256-9. 2004
    ..Severe acute respiratory syndrome (SARS) is a newly described form of atypical pneumonia linked to a novel coronavirus...
  32. ncbi request reprint Tuberculosis of the nasopharynx: a rare entity revisited
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Division of Otorhinolaryngology, Prince of Wales Hospital, Chinese University of Hong Kong, Republic of China
    Laryngoscope 113:737-40. 2003
    ..Tuberculosis of the nasopharynx is uncommon. A large series of 17 cases is reported, and the clinical and pathological features are discussed...
  33. ncbi request reprint Fine needle aspiration cytologic features of mammary phyllodes tumors
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Ngan Shing Street, Shatin, NT, Hong Kong SAR, China
    Acta Cytol 46:855-63. 2002
    ..To evaluate specific diagnostic fine needle aspiration cytologic (FNAC) features of phyllodes tumor (PT), particularly in the differentiation from fibroadenoma (FA)...
  34. ncbi request reprint Tumour angiogenesis and p53 protein expression in mammary phyllodes tumors
    Gary M K Tse
    Departments of Anatomical and Cellular Pathology, Prince of Wales Hospital, Hong Kong, China
    Mod Pathol 16:1007-13. 2003
    ..We conclude that microvessel density and p53 are useful as independent criteria in evaluating malignancy in phyllodes tumors...
  35. ncbi request reprint Increased p53 protein expression in malignant mammary phyllodes tumors
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Hong Kong, P R China
    Mod Pathol 15:734-40. 2002
    ..The role of p53 gene mutation in the malignant transformation of PT is unclear; but this may not be the sole mechanism as many malignant PT were p53 protein negative...
  36. pmc Ductal carcinoma in situ arising in mammary hamartoma
    G M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong SAR
    J Clin Pathol 55:541-2. 2002
    ..This report emphasises the importance of adequate sampling of mammary hamartoma...
  37. ncbi request reprint Basal cell adenocarcinoma of the salivary gland: report of a case with morphology on fine needle aspiration cytology
    G M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT
    Acta Cytol 45:775-8. 2001
    ..Basal cell adenocarcinoma of the parotid is rare and prone to recur...
  38. ncbi request reprint Fibromatosis of the head and neck region
    G M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong
    Otolaryngol Head Neck Surg 125:516-9. 2001
    ..Five cases of head and neck fibromatosis were analyzed. The imaging and pathologic findings, surgical management, and clinical outcome were discussed...
  39. ncbi request reprint Characterization of lesions of the breast with proton MR spectroscopy: comparison of carcinomas, benign lesions, and phyllodes tumors
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Ngan Shing St, Shatin, Hong Kong, SAR China
    AJR Am J Roentgenol 181:1267-72. 2003
    ..All lesions were larger than 1.5 cm. Tumor Ki-67 proliferative index, tumor angiogenesis, and HER2/neu oncogene overexpression were evaluated by immunohistochemistry of the histologic material...
  40. pmc Hamartoma of the breast: a clinicopathological review
    G M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong SAR, China
    J Clin Pathol 55:951-4. 2002
    ..To review 25 cases of breast hamartoma and discuss the pathological criteria, and the usefulness of imaging modalities, fine needle aspiration cytology (FNAC), and needle core biopsy in the diagnosis...
  41. ncbi request reprint Fine-needle aspiration cytology of breast carcinoma with endocrine differentiation
    G M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Hong Kong, China
    Cancer 90:286-91. 2000
    ..In the current study the authors review the FNA cytology of endocrine carcinoma and identify common cytologic features that allow for the diagnosis of this uncommon, low grade subtype of mammary malignancy...
  42. ncbi request reprint Multinucleated stromal giant cells in mammary phyllodes tumours
    G M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Hong Kong SAR, China
    Pathology 33:153-6. 2001
    ..In view of the small number of cases, the significance of such giant cells on the prognosis of PT remains uncertain...
  43. ncbi request reprint Increased microvessel density in malignant and borderline mammary phyllodes tumours
    G M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Shatin, China
    Histopathology 38:567-70. 2001
    ..The authors report the correlation between intratumoral microvessel density and the histological grade of phyllodes tumour...
  44. ncbi request reprint Sonographic appearance of mucinous carcinoma of the breast
    W W M Lam
    Department of Diagnostic Radiology and Organ Imaging, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing St, Shatin, New Territories, Hong Kong
    AJR Am J Roentgenol 182:1069-74. 2004
    ..The aim of this study was to evaluate the sonographic and mammographic features of mucinous carcinoma and to correlate the imaging features with two histologic classifications...
  45. ncbi request reprint A case of parotid mucoepidermoid carcinoma complicated by fatal gastrointestinal bleeding
    E W To
    Division of Head and Neck Plastic, Reconstructive, and Burns Surgery, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, N T, Hong Kong SAR
    Ear Nose Throat J 80:671-3. 2001
    ..Such a complication is unusual and to our knowledge has not been previously reported. We briefly discuss the clinical features, biologic behavior, and treatment of this tumor...
  46. ncbi request reprint Radiation induced sarcomas of the head and neck following radiotherapy for nasopharyngeal carcinoma
    A D King
    Departments of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Terorities
    Clin Radiol 55:684-9. 2000
    ..To report the radiological findings of radiation induced sarcomas (RIS) in the head and neck following radiotherapy for nasopharyngeal carcinoma...
  47. ncbi request reprint Human breast lesions: characterization with contrast-enhanced in vivo proton MR spectroscopy--initial results
    D K Yeung
    Department of Clinical Oncology, Medical Physics Division, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, Hong Kong, China
    Radiology 220:40-6. 2001
    ..To assess the clinical usefulness of localized proton (hydrogen 1) magnetic resonance (MR) spectroscopy in the characterization of contrast material-enhanced breast lesions on the basis of choline detection...
  48. ncbi request reprint Biopsy of deep-seated head and neck lesions under intraoral ultrasound guidance
    K T Wong
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Hong Kong, China
    AJNR Am J Neuroradiol 27:1654-7. 2006
    ..This article discusses the role of intraoral ultrasound and presents 3 cases in which biopsy of deep-seated neck masses under intraoral ultrasound guidance helped in diagnosis and management...
  49. ncbi request reprint Comparison of the sonographic features of acalculous and calculous submandibular sialadenitis
    A S Ching
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong
    J Clin Ultrasound 29:332-8. 2001
    ..Sonographic imaging in conjunction with fine-needle aspiration is useful for detection of this disorder...
  50. ncbi request reprint MR imaging of nonmalignant polyps and masses of the nasopharynx and sphenoid sinus after radiotherapy for nasopharyngeal carcinoma
    A D King
    Department of Diagnostic Radiology and Organ Imaging, Faculty of Medicine, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    AJNR Am J Neuroradiol 29:1209-14. 2008
    ..The purpose of this study was to document the MR appearance of unusual nonmalignant polyps or masses (NMPMs) in the nasopharynx and sphenoid sinus arising after radiation treatment of nasopharyngeal carcinoma...
  51. ncbi request reprint Heme oxygenase-1 protects against apoptosis induced by tumor necrosis factor-alpha and cycloheximide in papillary thyroid carcinoma cells
    George G Chen
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N T, Hong Kong SAR, China
    J Cell Biochem 92:1246-56. 2004
    ..The HO-1 pathway of apoptosis resistance is associated with an increase in the levels of p21, involves a p38 MAPK and ERK-mediated mechanism and can be suppressed by inhibiting NF-kappaB...
  52. ncbi request reprint Human cervical lymphadenopathy: evaluation with in vivo 1H-MRS at 1.5 T
    A D King
    Department of Diagnostic Radiology and Organ Imaging, Faculty of Medicine, The Chinese University of Hong Kong, Shatin
    Clin Radiol 60:592-8. 2005
    ..To evaluate the feasibility of performing in vivo proton magnetic resonance spectroscopy ((1)H-MRS) of cervical lymph nodes, and the clinical usefulness of the technique in the characterization of cervical lymphadenopathy...
  53. ncbi request reprint Computer-assisted detection as a second reader in symptomatic Asian women with palpable breast cancer
    W C W Chu
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    Acta Radiol 45:148-53. 2004
    ..To determine the potential role of a computer-assisted detection (CAD) algorithm as a second reader for experienced and inexperienced radiologists in mammography reading in Asian women...
  54. ncbi request reprint Cowden's disease with vocal fold involvement
    E W To
    Division of Head and Neck Plastic and Reconstructive Surgery, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, N T, Hong Kong SAR
    Ear Nose Throat J 80:754-6, 758. 2001
    ..The pattern of distribution and the histopathologic features of these mucocutaneous lesions were diagnostic of Cowden's disease. To the best of our knowledge, this is the first reported case of Cowden's disease involving a vocal fold...
  55. ncbi request reprint Metastatic thymic neuroendocrine carcinoma presenting as a pancreatic tumor
    Y T Lee
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Endoscopy 38:E58-9. 2006
  56. ncbi request reprint Calcium-mediated activation of PI3K and p53 leads to apoptosis in thyroid carcinoma cells
    Z M Liu
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
    Cell Mol Life Sci 64:1428-36. 2007
    ..These results suggested that apoptosis induced by cadmium in FRO cells was initiated by the rapid elevation of intracellular calcium, followed by calcium-mediated activation of PI3K/Akt and mitochondrial impairment...
  57. ncbi request reprint Induction of thyroid papillary carcinoma cell proliferation by estrogen is associated with an altered expression of Bcl-xL
    M L Lee
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N T, Hong Kong SAR, China
    Cancer J 11:113-21. 2005
    ..The aim of this study was to explore the mechanism by which sex hormones contribute to the development of thyroid carcinoma, which is not well understood at present...
  58. ncbi request reprint Ultrasound and MR imaging of diabetic mastopathy
    K T Wong
    Department of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Clin Radiol 57:730-5. 2002
    ..To review the imaging findings of diabetic mastopathy, and document the colour flow ultrasound and MR imaging features in this benign condition...
  59. pmc Pulmonary tumour microembolism clinically mimicking alveolitis
    A W I Lo
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong SAR, China
    J Clin Pathol 56:866-7. 2003
    ..In a patient with known malignancy, tumour microembolism should be considered as an uncommon cause of rapid respiratory failure, refractory to antibiotic treatment...
  60. ncbi request reprint In vivo proton MR spectroscopy of primary and nodal nasopharyngeal carcinoma
    Ann D King
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China
    AJNR Am J Neuroradiol 25:484-90. 2004
    ..The aim of this study was to determine the feasibility of performing in vivo proton ((1)H) MR spectroscopy of nasopharyngeal carcinoma (NPC) and to document the (1)H spectrum of this cancer...
  61. doi request reprint Fine needle aspiration cytology in young women with breast cancer: diagnostic difficulties
    Anjali Somani
    Department of Pathology, Singapore General Hospital, Singapore, Singapore
    Pathology 40:359-64. 2008
    ..Though fine needle aspiration cytology (FNAC) plays an important role in preoperative diagnosis, there may be diagnostic delays in affected young women due to a lower index of suspicion...
  62. ncbi request reprint Melanocytic and non-melanocytic oncocytic metaplasia of the nasopharynx
    Philip C W Lui
    Pathology 36:504-5. 2004
  63. ncbi request reprint Malignant cervical lymphadenopathy: diagnostic accuracy of diffusion-weighted MR imaging
    Ann D King
    Department of Diagnostic Radiology and Organ Imaging, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China
    Radiology 245:806-13. 2007
    ....
  64. ncbi request reprint Comparison of CT and MR imaging for the detection of extranodal neoplastic spread in metastatic neck nodes
    Ann D King
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, The Chinese University of Hong Kong, Ngan Shing Street, Shatin, New Territories, Hong Kong SAR, China
    Eur J Radiol 52:264-70. 2004
    ..To compare computed tomography (CT) and magnetic resonance (MR) imaging for the detection of extranodal neoplastic spread (ENS) in metastatic cervical nodes from head and neck squamous cell carcinoma...
  65. ncbi request reprint Fine needle aspiration cytology of lymph node with metastatic undifferentiated carcinoma and granulomatous (sarcoid-like) reaction
    Philip C W Lui
    Pathology 36:273-4. 2004
  66. pmc Human metapneumovirus-associated atypical pneumonia and SARS
    Paul K S Chan
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Emerg Infect Dis 10:497-500. 2004
    ..Human metapneumovirus was isolated from lung tissue. No other pathogen was found. Other etiologic agents should thus be sought in apparent SARS cases when coronavirus infection cannot be confirmed...
  67. ncbi request reprint Fine-needle aspiration cytology of pseudoangiomatous stromal hyperplasia of the breast
    Philip C W Lui
    Department of Pathology, United Christian Hospital, Hong Kong, China
    Diagn Cytopathol 30:353-5. 2004
    ..Two cases of PASH are reported with emphasis on the FNAC features and cytologic differentiation from other benign fibroepithelial lesions...
  68. ncbi request reprint Eccrine poroma: a differential diagnosis in chronic foot lesions
    Margaret W N Wong
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Foot Ankle Int 24:789-92. 2003
    ..It is emphasized that eccrine poroma should be considered in the differential diagnosis of chronic foot lesions. Complete excision prevents recurrence, excludes dysplastic change, and prevents future malignant change...
  69. ncbi request reprint Sonographic, mammographic, and histopathologic correlation of symptomatic ductal carcinoma in situ
    Wei Tse Yang
    Department of Diagnostic Radiology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong SAR, China
    AJR Am J Roentgenol 182:101-10. 2004
    ....
  70. ncbi request reprint Necrosis in metastatic neck nodes: diagnostic accuracy of CT, MR imaging, and US
    Ann D King
    Department of Diagnostic Radiology and Organ Imaging, Faculty of Medicine, Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing St, Shatin, New Territories, Hong Kong SAR, China
    Radiology 230:720-6. 2004
    ..To compare the diagnostic accuracy of computed tomography (CT), magnetic resonance (MR) imaging, and ultrasonography (US) in the detection of necrosis in metastatic cervical nodes from patients with head and neck squamous cell carcinoma...
  71. ncbi request reprint Nasopharyngeal granulomatous inflammation and tuberculosis complicating undifferentiated carcinoma
    Amy B W Chan
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories
    Otolaryngol Head Neck Surg 130:125-30. 2004
    ..Four cases of nasopharyngeal granulomatous inflammation after radiotherapy for undifferentiated carcinoma were analyzed for tuberculosis, and the histologic features were compared...
  72. ncbi request reprint Tissue and cellular tropism of the coronavirus associated with severe acute respiratory syndrome: an in-situ hybridization study of fatal cases
    K F To
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Hong Kong SAR, China
    J Pathol 202:157-63. 2004
    ..Whereas the lung pathology was dominated by diffuse alveolar damage, the gut was relatively intact. These findings indicated that tissue responses to SARS-CoV infection are distinct in different organs...
  73. ncbi request reprint Stromal expression of vascular endothelial growth factor correlates with tumor grade and microvessel density in mammary phyllodes tumors: a multicenter study of 185 cases
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Shatin, Hong Kong
    Hum Pathol 35:1053-7. 2004
    ..Assessment of stromal VEGF may be useful as an adjunctive diagnostic criterion in the histologic assessment of malignancy in phyllodes tumors...
  74. ncbi request reprint Fine needle aspiration cytology of invasive micropapillary carcinoma of the breast
    Philip C W Lui
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Pathology 39:401-5. 2007
    ..To determine the pathognomonic diagnostic cytological features of invasive micropapillary carcinoma of the breast which is a poor prognostic subtype of infiltrating ductal carcinoma...
  75. ncbi request reprint Metachronous bilateral mammary metaplastic and infiltrating duct carcinomas: a molecular study for clonality
    Fred Y l Kung
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital and P H Chan Medical Laboratories Limited, Hong Kong SAR
    Hum Pathol 33:677-9. 2002
    ..We demonstrated a second primary carcinoma in a patient with previous metaplastic carcinoma rather than a metastasis with carcinoma component only...
  76. ncbi request reprint Salivary gland tumors at in vivo proton MR spectroscopy
    Ann D King
    Department of Diagnostic Radiology and Organ Imaging, Faculty of Medicine, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Radiology 237:563-9. 2005
    ..To prospectively evaluate whether proton magnetic resonance (MR) spectroscopy can be used to characterize salivary gland tumors (SGTs)...
  77. ncbi request reprint Fine needle aspiration cytology of dermatofibrosarcoma protuberans in the breast: a case report
    Alex K H Tsang
    Pathology 37:84-6. 2005
  78. ncbi request reprint MR imaging features of nasopharyngeal tuberculosis: report of three cases and literature review
    Ann D King
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    AJNR Am J Neuroradiol 24:279-82. 2003
    ..Extension outside the confines of the nasopharynx was not a feature, except in one case with early involvement of the prevertebral muscles...
  79. ncbi request reprint Radiological appearance of postirradiation sarcoma of the chest wall after mastectomy
    Alice P Y Tang
    Department of Diagnostic Radiology, Alice Ho Miu Ling Nethersole Hospital, Hong Kong SAR, China
    Clin Imaging 29:185-8. 2005
    ..We report the computed tomography (CT) and magnetic resonance imaging (MRI) features of two patients who developed cutaneous high-grade sarcoma after mastectomy and irradiation for primary breast tumours more than 5 years ago...
  80. pmc Fine-needle aspiration cytology of metaplastic carcinoma of the breast
    Philip C W Lui
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    J Clin Pathol 60:529-33. 2007
    ..Metaplastic carcinoma of the breast encompasses a heterogeneous group of tumours with variable components of sarcomatoid, squamous or poorly differentiated carcinomas...
  81. pmc Cytology of chordoid meningioma: a series of five cases with emphasis on differential diagnoses
    Philip C W Lui
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    J Clin Pathol 60:1024-8. 2007
    ..It is classified as grade II (World Health Organization) tumours, as they have a tendency to behave more aggressively than traditional meningiomas and have a greater likelihood of recurrence...
  82. ncbi request reprint Delayed right ventricular intracavitary metastasis in a patient with Dukes B rectal adenocarcinoma
    Philip C W Lui
    Pathology 36:592-4. 2004
  83. ncbi request reprint Primary hepatic carcinoid tumours: report of two cases
    Patrick P L Lau
    Pathology 38:458-61. 2006
  84. ncbi request reprint Correlation between color power Doppler sonographic measurement of breast tumor vasculature and immunohistochemical analysis of microvessel density for the quantitation of angiogenesis
    Wei Tse Yang
    Department of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories
    J Ultrasound Med 21:1227-35. 2002
    ..To record the correlation between color power Doppler sonographic measurement of breast tumor vasculature and immunohistochemical analysis of microvessel density for the quantitation of angiogenesis...
  85. ncbi request reprint Breast cancer: in vivo proton MR spectroscopy in the characterization of histopathologic subtypes and preliminary observations in axillary node metastases
    David K W Yeung
    Department of Clinical Oncology, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, Hong Kong, China
    Radiology 225:190-7. 2002
    ....
  86. ncbi request reprint Hormonal receptors expression in epithelial cells of mammary phyllodes tumors correlates with pathologic grade of the tumor: a multicenter study of 143 cases
    Gary M K Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, NT, Hong Kong, People s Republic of China
    Am J Clin Pathol 118:522-6. 2002
    ..05). As the hormonal receptor protein expression shows a consistent decrease with increasing malignancy, we infer that the epithelium has a crucial role in the pathogenesis or progression of PT...
  87. ncbi request reprint In vivo 1H MR spectroscopy of thyroid carcinoma
    Ann D King
    Department of Diagnostic Radiology and Organ Imaging, Faculty of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, SAR China
    Eur J Radiol 54:112-7. 2005
    ..Our results showed that 1H MRS is a feasible technique for the evaluation of malignant thyroid tumors larger than 1 cm3 and that proton spectra of malignant tumors differ from that of normal thyroid tissue...
  88. ncbi request reprint Extratesticular epidermal cyst of the scrotum
    Wei Tse Yang
    Division of Diagnostic Imaging, M D Anderson Cancer Center, 1515 Holcombe Blvd, Box 57, Houston, TX 77030, USA
    AJR Am J Roentgenol 183:1084. 2004
  89. ncbi request reprint Mediastinal synovial sarcoma: a case report and literature review
    Linda S L Cheng
    Division of Cardiothoracic Surgery, Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China
    Can Respir J 10:393-5. 2003
    ..A case of mediastinal synovial sarcoma is described, of which the unusual location, diagnosis and treatment form the basis of this report...
  90. ncbi request reprint Intracortical chondroma in a 7-year-old boy and literature review
    Philip C W Lui
    Pathology 38:186-9. 2006
  91. ncbi request reprint Comparative studies of various ganoderma species and their different parts with regard to their antitumor and immunomodulating activities in vitro
    Grace G L Yue
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    J Altern Complement Med 12:777-89. 2006
    ....
  92. ncbi request reprint Pathologic quiz case: a solitary breast nodule in an elderly woman. Fasciitis ossificans of the breast
    Philip C W Lui
    Department of Pathology, United Christian Hospital, Hong Kong, China
    Arch Pathol Lab Med 128:e29-30. 2004
  93. ncbi request reprint 'Leafy' pattern in phyllodes tumour of the breast: MRI-pathologic correlation
    Humairah S Cheung
    Clin Radiol 57:230-1. 2002