Ling Qin

Summary

Affiliation: The Chinese University of Hong Kong
Country: China

Publications

  1. ncbi Multiple bioimaging modalities in evaluation of an experimental osteonecrosis induced by a combination of lipopolysaccharide and methylprednisolone
    L Qin
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, PR China
    Bone 39:863-71. 2006
  2. ncbi [Multiple bioimaging modalities in evaluation of an experimental osteonecrosis model induced by a combination of lipopolysaccharide and methylprednisolone]
    Ling Qin
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, Chinese University of Hong Kong, Hong Kong SAR, P R China
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 22:258-64. 2008
  3. ncbi Beneficial effects of regular Tai Chi exercise on musculoskeletal system
    Ling Qin
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    J Bone Miner Metab 23:186-90. 2005
  4. ncbi Low-intensity pulsed ultrasound accelerates osteogenesis at bone-tendon healing junction
    Ling Qin
    Musculo Skeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, NT Hong Kong
    Ultrasound Med Biol 32:1905-11. 2006
  5. ncbi Correlation study of scanning acoustic microscope reflection coefficients and image brightness intensities of micrographed osteons
    Ling Qin
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China
    J Bone Miner Metab 22:86-9. 2004
  6. ncbi Osteogenesis induced by extracorporeal shockwave in treatment of delayed osteotendinous junction healing
    Ling Qin
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, N T Hong Kong SAR, China
    J Orthop Res 28:70-6. 2010
  7. ncbi Baseline BMD and bone loss at distal radius measured by peripheral quantitative computed tomography in peri- and postmenopausal Hong Kong Chinese women
    L Qin
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong
    Osteoporos Int 13:962-70. 2002
  8. ncbi Regular Tai Chi Chuan exercise may retard bone loss in postmenopausal women: A case-control study
    Ling Qin
    Department of Orthopaedics and Traumatology, Chinese University of Hong Kong, Hong Kong
    Arch Phys Med Rehabil 83:1355-9. 2002
  9. ncbi Low intensity pulsed ultrasound increases the matrix hardness of the healing tissues at bone-tendon insertion-a partial patellectomy model in rabbits
    Ling Qin
    Musculo Skeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, NT
    Clin Biomech (Bristol, Avon) 21:387-94. 2006
  10. ncbi Enlargement of remaining patella after partial patellectomy in rabbits
    L Qin
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, NT
    Med Sci Sports Exerc 31:502-6. 1999

Collaborators

Detail Information

Publications123 found, 100 shown here

  1. ncbi Multiple bioimaging modalities in evaluation of an experimental osteonecrosis induced by a combination of lipopolysaccharide and methylprednisolone
    L Qin
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, PR China
    Bone 39:863-71. 2006
    ....
  2. ncbi [Multiple bioimaging modalities in evaluation of an experimental osteonecrosis model induced by a combination of lipopolysaccharide and methylprednisolone]
    Ling Qin
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, Chinese University of Hong Kong, Hong Kong SAR, P R China
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 22:258-64. 2008
    ....
  3. ncbi Beneficial effects of regular Tai Chi exercise on musculoskeletal system
    Ling Qin
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    J Bone Miner Metab 23:186-90. 2005
    ..41; P<0.01). This study revealed that regular TCC exercise may have an association with higher BMD and better neuromuscular function in early postmenopausal women...
  4. ncbi Low-intensity pulsed ultrasound accelerates osteogenesis at bone-tendon healing junction
    Ling Qin
    Musculo Skeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, NT Hong Kong
    Ultrasound Med Biol 32:1905-11. 2006
    ..Findings of this study formed a scientific basis for future clinical trials and establishment of indication of LIPUS for enhancing bone-tendon junction repair...
  5. ncbi Correlation study of scanning acoustic microscope reflection coefficients and image brightness intensities of micrographed osteons
    Ling Qin
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China
    J Bone Miner Metab 22:86-9. 2004
    ..99 ( P << 0.001) using gray level 210 as cutoff. This result suggested that the image brightness intensity of osteonic bone could be measured retrospectively to provide information on the stiffness of the corresponding bone matrix...
  6. ncbi Osteogenesis induced by extracorporeal shockwave in treatment of delayed osteotendinous junction healing
    Ling Qin
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, N T Hong Kong SAR, China
    J Orthop Res 28:70-6. 2010
    ..These findings formed a scientific basis to potential clinical application of ESW for treatment of delayed OTJ healing...
  7. ncbi Baseline BMD and bone loss at distal radius measured by peripheral quantitative computed tomography in peri- and postmenopausal Hong Kong Chinese women
    L Qin
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong
    Osteoporos Int 13:962-70. 2002
    ....
  8. ncbi Regular Tai Chi Chuan exercise may retard bone loss in postmenopausal women: A case-control study
    Ling Qin
    Department of Orthopaedics and Traumatology, Chinese University of Hong Kong, Hong Kong
    Arch Phys Med Rehabil 83:1355-9. 2002
    ..To evaluate the potential benefits of regular Tai Chi Chuan exercise on the weight-bearing bones of postmenopausal women...
  9. ncbi Low intensity pulsed ultrasound increases the matrix hardness of the healing tissues at bone-tendon insertion-a partial patellectomy model in rabbits
    Ling Qin
    Musculo Skeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, NT
    Clin Biomech (Bristol, Avon) 21:387-94. 2006
    ..This study evaluated the low intensity pulsed ultrasound enhancement on matrix hardness of the healing tissues at the bone-tendon junction...
  10. ncbi Enlargement of remaining patella after partial patellectomy in rabbits
    L Qin
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, NT
    Med Sci Sports Exerc 31:502-6. 1999
    ..The purpose was to study the radiographic patellar tendon calcification and evaluate the histology of the healing interface between the patellar tendon and the remaining patella after partial patellectomy...
  11. ncbi Phytoestrogen-rich herb formula "XLGB" prevents OVX-induced deterioration of musculoskeletal tissues at the hip in old rats
    Ling Qin
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, N T Hong Kong SAR, PR China
    J Bone Miner Metab 23:55-61. 2005
    ..In conclusion, findings of this study suggested that the herbal preparation XLGB was able to prevent OVX-induced deterioration of musculoskeletal tissues at the hip without causing uterine stimulation...
  12. ncbi Histomorphological study on pattern of fluid movement in cortical bone in goats
    L Qin
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong
    Anat Rec 255:380-7. 1999
    ..The results suggest that the undecalcified technique might be a useful method for qualitative and quantitative studies on cortical fluid flow...
  13. ncbi [Epimedium-derived flavonoids prevent ovariectomy-induced osteoporosis in rats independent of its enhancement in intestinal calcium absorption]
    Ling Qin
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, Chinese University of Hong Kong, Hong Kong SAR, China
    Zhonghua Yi Xue Za Zhi 88:1772-7. 2008
    ..To test our hypothesis whether a group of flavonoids (FE) derived from herbal Epimedium exerted its prevention of estrogen-deficiency-induced osteoporosis mainly through an enhancement in intestinal calcium absorption...
  14. ncbi Exogenous phytoestrogenic molecule icaritin incorporated into a porous scaffold for enhancing bone defect repair
    Xin Luan Wang
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China
    J Orthop Res 31:164-72. 2013
    ..The supplement of scaffold materials with bioactive phytomolecule(s) might improve treatment efficiency in challenging orthopedic conditions...
  15. ncbi Low-intensity pulsed ultrasound accelerated bone-tendon junction healing through regulation of vascular endothelial growth factor expression and cartilage formation
    Hongbin Lu
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, PR China
    Ultrasound Med Biol 34:1248-60. 2008
    ..In conclusion, this was the first quantitative study to demonstrate that LIPUS improved B-T junction healing through regulation of VEGF expression in early healing phase and subsequent chondrogenesis...
  16. ncbi Low-intensity pulsed ultrasound accelerates bone-tendon junction healing: a partial patellectomy model in rabbits
    Hongbin Lu
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong
    Am J Sports Med 34:1287-96. 2006
    ..CLINICAL RELEVANCE: These results may help establish treatment efficacy for accelerating bone-to-tendon junction repair and facilitating earlier rehabilitation...
  17. ncbi Continuous occurrence of both insufficient neovascularization and elevated vascular permeability in rabbit proximal femur during inadequate repair of steroid-associated osteonecrotic lesions
    Ge Zhang
    Chinese University of Hong Kong, Hong Kong, China
    Arthritis Rheum 60:2966-77. 2009
    ....
  18. ncbi Influence of bone adaptation on tendon-to-bone healing in bone tunnel after anterior cruciate ligament reconstruction in a rabbit model
    Chun Yi Wen
    Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China
    J Orthop Res 27:1447-56. 2009
    ..In conclusion, the postoperative bone loss and associated poor T-B healing was region-dependent, which may result from adaptive changes after tunnel creation...
  19. ncbi Epimedium-derived flavonoids promote osteoblastogenesis and suppress adipogenesis in bone marrow stromal cells while exerting an anabolic effect on osteoporotic bone
    Songlin Peng
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, N T Hong Kong SAR, China
    Bone 45:534-44. 2009
    ..Epimedium-derived flavonoids (EFs) have been reported to prevent bone loss in ovariectomized (OVX) rats and late postmenopausal women but the underlying mechanism of the anabolic effect is unknown...
  20. ncbi Low-intensity pulsed ultrasound enhances posterior spinal fusion implanted with mesenchymal stem cells-calcium phosphate composite without bone grafting
    Celine Fan Fong Hui
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, N T, Hong Kong
    Spine (Phila Pa 1976) 36:1010-6. 2011
    ..Experimental study on the effect of low-intensity pulsed ultrasound (LIPUS) on rabbit spinal fusion with mesenchymal stem cell (MSC)-derived osteogenic cells and bioceramic composite...
  21. ncbi Structural and degradation characteristics of an innovative porous PLGA/TCP scaffold incorporated with bioactive molecular icaritin
    Xin Hui Xie
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, People s Republic of China
    Biomed Mater 5:054109. 2010
    ..In vivo confirmation is, however, needed to substantiate our in vitro findings...
  22. ncbi Reduced bone perfusion in osteoporosis: likely causes in an ovariectomy rat model
    James F Griffith
    Departments of Diagnostic Radiology and Organ Imaging, Anatomy, Physiology, and Orthopedics and Traumatology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT, Hong Kong
    Radiology 254:739-46. 2010
    ..c) RSNA, 2010 Supplemental material: http://radiology.rsna.org/lookup/suppl/doi:10.1148/radiol.09090608/-/DC1...
  23. ncbi Abnormal bone quality in adolescent idiopathic scoliosis: a case-control study on 635 subjects and 269 normal controls with bone densitometry and quantitative ultrasound
    Tsz Ping Lam
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, SAR, China
    Spine (Phila Pa 1976) 36:1211-7. 2011
    ..A case-control study comparing bone quality in Adolescent Idiopathic Scoliosis (AIS) with normal controls...
  24. ncbi A novel semisynthesized small molecule icaritin reduces incidence of steroid-associated osteonecrosis with inhibition of both thrombosis and lipid-deposition in a dose-dependent manner
    Ge Zhang
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, N T Hong Kong SAR
    Bone 44:345-56. 2009
    ..Further, the authors have recently identified a small molecule Icaritin as an intestinal metabolite of Epimedium-derived flavonoids...
  25. ncbi Dose-dependent effect of low-intensity pulsed ultrasound on callus formation during rapid distraction osteogenesis
    Chun Wai Chan
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, N.T, Hong Kong
    J Orthop Res 24:2072-9. 2006
    ..In conclusion, LIPUS was able to enhance bone regeneration under rapid distraction, and its effect was dose-dependent...
  26. ncbi Shockwave exerts osteogenic effect on osteoporotic bone in an ovariectomized goat model
    Kam Fai Tam
    Department of Orthopaedics and Traumatology, Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    Ultrasound Med Biol 35:1109-18. 2009
    ..These findings suggest that ESW treatment could enhance local BMD by inducing new bone formation, yet the effect was more apparent in non-weight-bearing sites...
  27. ncbi Extracorporeal shock wave therapy in treatment of delayed bone-tendon healing
    Lin Wang
    Musculoskeletal Research Laboratory, Department of Orthopaedics andTraumatology, The Chinese University of Hong Kong, Shatin, N T, Hong Kong SAR, China
    Am J Sports Med 36:340-7. 2008
    ..No investigation has been conducted to study the effect of shock wave on delayed healing at the bone-tendon junction...
  28. ncbi Association of osteopenia with curve severity in adolescent idiopathic scoliosis: a study of 919 girls
    Warren T K Lee
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Osteoporos Int 16:1924-32. 2005
    ..The study implied that prevention of osteopenia could be as important as controlling spinal progression in the management of AIS...
  29. ncbi Bone microarchitecture assessment by high-resolution peripheral quantitative computed tomography in patients with systemic lupus erythematosus taking corticosteroids
    Edmund K Li
    Department of Medicine and Therapeutics, Prince of Wales Hospital, Shatin, Hong Kong
    J Rheumatol 37:1473-9. 2010
    ....
  30. ncbi Low intensity pulsed ultrasound accelerated bone remodeling during consolidation stage of distraction osteogenesis
    Chun Wai Chan
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N.T, Hong Kong
    J Orthop Res 24:263-70. 2006
    ..8+/-895.1 N . mm). In conclusion, the effective period of LIPUS treatment was at the initial stage of consolidation, with accelerated bone formation and remodeling...
  31. ncbi Stimulated angiogenesis for fracture healing augmented by low-magnitude, high-frequency vibration in a rat model-evaluation of pulsed-wave doppler, 3-D power Doppler ultrasonography and micro-CT microangiography
    Wing Hoi Cheung
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    Ultrasound Med Biol 38:2120-9. 2012
    ..Despite impaired neo-angiogenesis in osteoporotic fractures, LMHFV could increase blood flow and angiogenesis in both normal and osteoporotic fractures, thus enhancing fracture healing...
  32. ncbi Icaritin, an exogenous phytomolecule, enhances osteogenesis but not angiogenesis--an in vitro efficacy study
    Dong Yao
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong
    PLoS ONE 7:e41264. 2012
    ..Though some flavonoids were shown to regulate the coupling process of angiogenesis and osteogenesis during bone repair, our results suggested that Icaritin did not have direct effect on enhancing angiogenesis in vitro...
  33. ncbi Three-dimensional high frequency power Doppler ultrasonography for the assessment of microvasculature during fracture healing in a rat model
    Ming Hui Sun
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, People s Republic of China
    J Orthop Res 30:137-43. 2012
    ..Osteoporotic rats had a diminished angiogenic response and lower blood perfusion than Shams. We believe 3D-HF-PDU is feasible and reproducible for in vivo assessment of microvasculature during femoral fracture healing in rats...
  34. ncbi Generalized osteopenia in adolescent idiopathic scoliosis--association with abnormal pubertal growth, bone turnover, and calcium intake?
    Catherine Siu King Cheung
    Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin
    Spine (Phila Pa 1976) 31:330-8. 2006
    ..A cross-sectional study in girls with adolescent idiopathic scoliosis (AIS) and healthy counterparts of similar age...
  35. ncbi Grafted tendon healing in tibial tunnel is inferior to healing in femoral tunnel after anterior cruciate ligament reconstruction: a histomorphometric study in rabbits
    Chun Yi Wen
    Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, China
    Arthroscopy 26:58-66. 2010
    ..This study aimed to test whether graft healing in the tibial tunnel was inferior to that in the femoral tunnel after anterior cruciate ligament (ACL) reconstruction in rabbits...
  36. ncbi Low-magnitude high-frequency vibration accelerates callus formation, mineralization, and fracture healing in rats
    Kwok Sui Leung
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, People s Republic of China
    J Orthop Res 27:458-65. 2009
    ..It is concluded that LMHFV enhances healing in the closed femoral shaft fracture in rats. The potential clinical advantages shall be confirmed in the subsequent clinical trials...
  37. ncbi Osteogenic effects of low-intensity pulsed ultrasound, extracorporeal shockwaves and their combination - an in vitro comparative study on human periosteal cells
    Kam Fai Tam
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    Ultrasound Med Biol 34:1957-65. 2008
    ..Although these findings suggest that ESW and LIPUS stimulate the periosteal cells in two different ways and at different times, their additive or synergistic effects could not be proven...
  38. ncbi The use of brushite calcium phosphate cement for enhancement of bone-tendon integration in an anterior cruciate ligament reconstruction rabbit model
    Chun Yi Wen
    Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China
    J Biomed Mater Res B Appl Biomater 89:466-74. 2009
    ..013). Brushite CPC significantly enhanced the bone-tendon integration after ACL reconstruction, which provided a scientific basis for clinical application...
  39. ncbi Evaluation of bone-tendon junction healing using water jet ultrasound indentation method
    Min Hua Lu
    Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China
    Ultrasound Med Biol 35:1783-93. 2009
    ....
  40. ncbi Low-magnitude high-frequency vibration (LMHFV) enhances bone remodeling in osteoporotic rat femoral fracture healing
    Dick Ho Kiu Chow
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, 5 F, Clinical Science Building, Shatin, New Territories, Hong Kong SAR, People s Republic of China
    J Orthop Res 29:746-52. 2011
    ..In conclusion, LMHFV accelerated fracture healing by enhancing bone remodeling and the administration of ibandronate can impair this enhancement. LMHFV has great potential in improving fracture outcome clinically...
  41. ncbi Promotion of bone repair by implantation of cryopreserved bone marrow-derived mononuclear cells in a rabbit model of steroid-associated osteonecrosis
    Xin Hui Xie
    The Chinese University of Hong Kong, Hong Kong, China
    Arthritis Rheum 64:1562-71. 2012
    ..This study sought to investigate the effects of cryopreserved BMMNCs, before steroid administration, on the enhancement of bone repair in an established rabbit model of SAON...
  42. ncbi Healing compared between bone to tendon and cartilage to tendon in a partial inferior patellectomy model in rabbits
    Hongbin Lu
    Department of Orthopaedics and Traumatology, Musculoskeletal Research Laboratory, The Chinese University of Hong Kong, Shatin, N T Hong Kong
    Clin J Sport Med 18:62-9. 2008
    ..This study was designed to perform a quantitative evaluation on healing characteristics at the cartilage-to-tendon (C-T) and the bone-to-tendon (B-T) healing junction in a temporal and spatial manner...
  43. ncbi Epimedium-derived phytoestrogen flavonoids exert beneficial effect on preventing bone loss in late postmenopausal women: a 24-month randomized, double-blind and placebo-controlled trial
    Ge Zhang
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, China
    J Bone Miner Res 22:1072-9. 2007
    ....
  44. ncbi The association of disproportionate skeletal growth and abnormal radius dimension ratio with curve severity in adolescent idiopathic scoliosis
    Wei Jun Wang
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, 5 F, Clinical Science Building, Shatin, NT, Hong Kong SAR, China
    Eur Spine J 19:726-31. 2010
    ..The observation of the association of radius dimension ratio with curve severity provides an important potentially clinically measurable parameter for further longitudinal studies on the prognostication of curve progression in AIS...
  45. ncbi Trabecular bone status in ultradistal tibia under habitual gait loading: a pQCT study in postmenopausal women
    Yau-Ming Lai
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, PR China
    J Clin Densitom 9:175-83. 2006
    ..However, the low-impact weight-bearing nature of a normal gait may not be osteogenic to prevent regional bone loss. An exercise program specific to the women at risk should be contemplated...
  46. ncbi Low-intensity pulsed ultrasound increases cellular uptake of superparamagnetic iron oxide nanomaterial: results from human osteosarcoma cell line U2OS
    Yi Xiang J Wang
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China
    J Magn Reson Imaging 31:1508-13. 2010
    ..To determine whether low-intensity pulsed ultrasound (LIPUS) is able to facilitate the uptake of a superparamagnetic iron oxide (SPIO) nanomaterial by cells that do not express high endocytosis capacity...
  47. ncbi Osteogenic effects of flavonoid aglycones from an osteoprotective fraction of Drynaria fortunei--an in vitro efficacy study
    Xinluan Wang
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China
    Phytomedicine 18:868-72. 2011
    ..This study provides scientific evidences for the conduction of in vivo experiments to confirm potential effects of flavonoid aglycones on preventing OVX-induced osteoporosis...
  48. ncbi Restoration of longitudinal growth by bioengineered cartilage pellet in physeal injury is not affected by low intensity pulsed ultrasound
    Simon Kwoon Ho Chow
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    J Biomed Mater Res B Appl Biomater 99:36-44. 2011
    ..05). No significant difference was found between GC and GT group. Femoral longitudinal growth was shown to be improved by the BCP, however no additional enhancement effect was shown to be provided by LIPUS...
  49. ncbi Generalized low bone mass of girls with adolescent idiopathic scoliosis is related to inadequate calcium intake and weight bearing physical activity in peripubertal period
    Warren T K Lee
    Department of Orthopaedics and Traumatology, 5/F, Clinical Sciences Building, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Osteoporos Int 16:1024-35. 2005
    ..The importance of preventing generalized osteopenia in the control of AIS progression during the peripubertal period warrants further study...
  50. ncbi A randomized, prospective study of the effects of Tai Chi Chun exercise on bone mineral density in postmenopausal women
    Kaiming Chan
    Department of Orthopaedics and Traumatology, Chinese University of Hong Kong, Hong Kong
    Arch Phys Med Rehabil 85:717-22. 2004
    ..Long-term follow-up is needed to substantiate the role of TCC exercise in the prevention of osteoporosis and its related fracture...
  51. ncbi High-frequency whole-body vibration improves balancing ability in elderly women
    Wing Hoi Cheung
    Department of Orthopaedics and Traumatology, Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    Arch Phys Med Rehabil 88:852-7. 2007
    ..To investigate the efficacy of high-frequency whole-body vibration (WBV) on balancing ability in elderly women...
  52. ncbi Fast and accurate 3-D registration of HR-pQCT images
    Lin Shi
    Department of Imaging and Interventional Radiology, The Chinese University of Hong Kong, Shatin, Hong Kong
    IEEE Trans Inf Technol Biomed 14:1291-7. 2010
    ..This automatic and accurate matching procedure may contribute to the clinical application and research of HR-pQCT...
  53. ncbi Constitutional flavonoids derived from Epimedium dose-dependently reduce incidence of steroid-associated osteonecrosis not via direct action by themselves on potential cellular targets
    Ge Zhang
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China
    PLoS ONE 4:e6419. 2009
    ..The underlying mechanism could be explained by counteracting endothelium injury and excessive adipogenesis. These findings encourage designing clinical trials to investigate potential of EF in prevention of steroid-associated ON...
  54. ncbi Proximal femur bone marrow blood perfusion indices are reduced in hypertensive rats: a dynamic contrast-enhanced MRI study
    Ya Feng Zhang
    Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT, Hong Kong, China
    J Magn Reson Imaging 30:1139-44. 2009
    ..To investigate the differences in proximal femoral bone marrow blood perfusion indices between hypertensive and normotensive rats using perfusion magnetic resonance imaging (MRI)...
  55. ncbi Functional perfusion MRI predicts later occurrence of steroid-associated osteonecrosis: an experimental study in rabbits
    Hui Sheng
    Musculoskeletal Research Laboratory of the Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    J Orthop Res 27:742-7. 2009
    ..Our experimental data suggested that perfusion MRI might be a sensitive noninvasive modality for monitoring steroid-associated ON in patients...
  56. ncbi Low intensity pulsed ultrasound enhances fracture healing in both ovariectomy-induced osteoporotic and age-matched normal bones
    Wing Hoi Cheung
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    J Orthop Res 30:129-36. 2012
    ..These comparable results on healing responses imply that LIPUS can be applied clinically to enhance both normal and osteoporotic fracture healing...
  57. ncbi Vertebral blood perfusion reduction associated with vertebral bone mineral density reduction: a dynamic contrast-enhanced MRI study in a rat orchiectomy model
    Yi Xiang J Wang
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, People s Republic of China
    J Magn Reson Imaging 28:1515-8. 2008
    ..To investigate the relationship between vertebral blood perfusion and vertebral bone mineral density (BMD) in a rat orchiectomy (ORX) model...
  58. ncbi Articular cartilage increases transition zone regeneration in bone-tendon junction healing
    Margaret Wan Nar Wong
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Clin Orthop Relat Res 467:1092-100. 2009
    ....
  59. ncbi Increased organ damage associated with deterioration in volumetric bone density and bone microarchitecture in patients with systemic lupus erythematosus on longterm glucocorticoid therapy
    Xiao lin Tang
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    J Rheumatol 39:1955-63. 2012
    ..To evaluate bone quality in patients with systemic lupus erythematosus (SLE) who were undergoing longterm glucocorticoid (GC) therapy, and to focus on the correlation between bone quality and organ damage...
  60. ncbi Radix Dipsaci does not improve tendon healing in a rat model of patellar tendon donor site injury
    Kai Ming Chan
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, Hong Kong, China
    Orthop Surg 2:187-93. 2010
    ..To explore whether Radix Dipsaci (RD) exhibits beneficial effects on tendon healing...
  61. ncbi Low-magnitude high-frequency vibration treatment augments fracture healing in ovariectomy-induced osteoporotic bone
    Hong Fei Shi
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    Bone 46:1299-305. 2010
    ..The findings of this study provide a good basis to suggest that proceeding to clinical trials is the next step to evaluate the efficacy of LMHFV on osteoporotic fracture healing...
  62. ncbi Impaired bone healing pattern in mice with ovariectomy-induced osteoporosis: A drill-hole defect model
    Yi Xin He
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Bone 48:1388-400. 2011
    ..To establish a drill-hole defect model in osteoporotic mouse femur by comparing temporal cortical bone healing pattern between OVX-induced osteoporotic bone and sham-operated bone...
  63. ncbi Identification of genes responsive to low-intensity pulsed ultrasound stimulations
    Hongbin Lu
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, N T, Hong Kong SAR, PR China
    Biochem Biophys Res Commun 378:569-73. 2009
    ..These results provide further understanding of the role of LIPUS in the regulation of osteoblastic gene expression potentially involved in the molecular mechanism of osteogenesis in fracture repair...
  64. ncbi Fracture healing enhancement with low intensity pulsed ultrasound at a critical application angle
    Shu Lu Chung
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, China
    Ultrasound Med Biol 37:1120-33. 2011
    ..LIPUS transmitted at a critical application angle may have greater enhancement effects in fracture healing...
  65. ncbi Low-intensity pulsed ultrasound on tendon healing: a study of the effect of treatment duration and treatment initiation
    Sai Chuen Fu
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
    Am J Sports Med 36:1742-9. 2008
    ..Low-intensity pulsed ultrasound has been reported to be effective in promoting tendon healing. However, its optimal time and duration has not yet been determined...
  66. ncbi Real-time ultrasonic assessment of progressive proteoglycan depletion in articular cartilage
    Qing Wang
    Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong, China
    Ultrasound Med Biol 34:1085-92. 2008
    ....
  67. ncbi A comparative study between axial compression and lateral fall configuration tested in a rat proximal femur model
    Ge Zhang
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong SAR, PR China
    Clin Biomech (Bristol, Avon) 20:729-35. 2005
    ..This study was therefore designed to evaluate the differences in hip mechanical failure force to be tested between 'axial compression' and 'lateral fall configuration' in a rat proximal femur model...
  68. ncbi Bone densitometry: which skeletal sites are best predicted by bone mass determinants?
    Warren T K Lee
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, 5 F Clinical Sciences Building, Prince of Wales Hospital, Hong Kong, Shatin, PR China
    J Bone Miner Metab 22:447-55. 2004
    ..Also, the development of composite index scores could help reduce the number of variables for correlation and outcome prediction analyses...
  69. ncbi Characteristics of long bone DXA reference data in Hong Kong Chinese
    Kwok Sui Leung
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    J Clin Densitom 7:192-200. 2004
    ..The age-related changes in the femoral diameter in females might attenuate the negative impact on fracture risk as a result of decreasing BMD with age...
  70. ncbi A relook into the association of the estrogen receptor [alpha] gene (PvuII, XbaI) and adolescent idiopathic scoliosis: a study of 540 Chinese cases
    Nelson Leung Sang Tang
    Department of Chemical Pathology, Chinese University of Hong Kong, Hong Kong
    Spine (Phila Pa 1976) 31:2463-8. 2006
    ..A genetic association study of estrogen receptor-[alpha] gene (ESR1) with adolescent idiopathic scoliosis (AIS) in Chinese...
  71. ncbi A comparative study of bone to bone repair and bone to tendon healing in patella-patellar tendon complex in rabbits
    Kwok Sui Leung
    Musculo-Skeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Clinical Sciences Building, Prince of Wales Hospital, Shatin, N.T, Hong Kong
    Clin Biomech (Bristol, Avon) 17:594-602. 2002
    ..However whenever possible, to initial fracture (bone-to-bone) fixation for ensuring better and predictable repair at the healing interface...
  72. ncbi Effects of basic fibroblast growth factor (bFGF) on early stages of tendon healing: a rat patellar tendon model
    B P Chan
    Department of Orthopedics and Traumatology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT
    Acta Orthop Scand 71:513-8. 2000
    ..Only time significantly affected both strength-associated parameters. We showed that in vivo supplementation with bFGF affected the initial events of healing such as cell proliferation and type III collagen expression...
  73. ncbi Peri-graft bone mass and connectivity as predictors for the strength of tendon-to-bone attachment after anterior cruciate ligament reconstruction
    Chun Yi Wen
    Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China
    Bone 45:545-52. 2009
    ..The measurement of peri-graft bone should be useful to monitor the quality of T-B healing and guide the postoperative rehabilitation...
  74. ncbi Rat lumbar vertebrae bone densitometry using multidetector CT
    Yi Xiang J Wang
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, People s Republic of China
    Eur Radiol 19:882-90. 2009
    ..7 +/- 6.7% BMD reduction at 28 days. Clinical MDCT can reliably and accurately measure rat lumbar vertebral BMD and is much faster than pQCT...
  75. ncbi Immobilization-induced changes in erythrocyte membrane fluidity in rabbits: a spin-label electron spin resonance study
    Mingju Liu
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, People s Republic of China
    Ann Clin Lab Sci 32:399-403. 2002
    ..These results may be helpful in studying the pathophysiology of immobilization...
  76. ncbi Low-intensity pulsed ultrasound accelerated callus formation, angiogenesis and callus remodeling in osteoporotic fracture healing
    Wing Hoi Cheung
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Ultrasound Med Biol 37:231-8. 2011
    ..We conclude that LIPUS can accelerate osteoporotic fracture healing by enhancing callus formation, angiogenesis and callus remodeling...
  77. ncbi [Trabecular bone micro-architecture in adolescent idiopathic scoliosis compared between concave and convex site of the facet joints]
    Hiu Yan Yeung
    Department of Orthopaedics and Traumatology, Chinese University of Hong Kong, Hong Kong, China
    Zhonghua Wai Ke Za Zhi 43:777-80. 2005
    ..To evaluate the trabecular bone micro-structure from different sites of spine in adolescent idiopathic scoliosis patients. The target site consisted of the bilateral facet joints from apical vertebrae and from end vertebrae...
  78. ncbi An in vitro optimized injectable calcium phosphate cement for augmenting screw fixation in osteopenic goats
    Kwok Sui Leung
    Department of Orthopaedics and Traumatology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong Special Administrative Region, People s Republic of China
    J Biomed Mater Res B Appl Biomater 78:153-60. 2006
    ..The optimized cement in this study may serve as a good candidate for augmenting fixation of osteoporotic bone...
  79. ncbi Ibandronate increases cortical bone density in patients with systemic lupus erythematosus on long-term glucocorticoid
    Edmund K Li
    Department of Medicine, The Chinese University of Hong Kong, Prince Wales Hospital, 30 32 Ngan Shing Street, Sha Tin, NT, Hong Kong, PR China
    Arthritis Res Ther 12:R198. 2010
    ....
  80. ncbi Biology and augmentation of tendon-bone insertion repair
    Ppy Lui
    Department of Orthopaedics and Traumatology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong SAR, China
    J Orthop Surg Res 5:59. 2010
    ..Recent development in the improvement of TBI healing and directions for future studies were also reviewed and discussed...
  81. ncbi Pyridinoline in relation to ultimate stress of the patellar tendon during healing: an animal study
    B P Chan
    Department of Orthopaedics and Traumatology, Chinese University of Hong Kong, Shatin, NT
    J Orthop Res 16:597-603. 1998
    ..This study also suggests the possibility of using pyridinoline content as an indirect marker of the ultimate stress because in vivo assessment is impossible...
  82. ncbi Osteopenia in adolescent idiopathic scoliosis: a histomorphometric study
    J C Cheng
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, Chinese University of Hong Kong
    Spine (Phila Pa 1976) 26:E19-23. 2001
    ..Bone biopsies from iliac crest and spinous process of adolescent idiopathic scoliosis patients were obtained intraoperatively for histology and histomorphometric analysis...
  83. ncbi Delayed stimulatory effect of low-intensity shockwaves on human periosteal cells
    Kam-Fai Tam
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    Clin Orthop Relat Res 438:260-5. 2005
    ..5 mJ/mm at 300 shocks). These findings document some of the biochemical changes of periosteal cells during shockwave treatments...
  84. ncbi pQCT bone strength index may serve as a better predictor than bone mineral density for long bone breaking strength
    Wing Sum Siu
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, Hong Kong
    J Bone Miner Metab 21:316-22. 2003
    ..Further clinical studies are needed to validate the predictive value of BSI in long bone osteoporotic fracture...
  85. ncbi The effects of verbascoside on plasma lipid peroxidation level and erythrocyte membrane fluidity during immobilization in rabbits: a time course study
    Ming-Ju Liu
    Department of Orthopaedics and Traumatology, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    Life Sci 73:883-92. 2003
    ..Verbascoside might have the effects to moderate oxidative stress and erythrocyte membrane fluidity during immobilization...
  86. ncbi Dosing effects of an antiosteoporosis herbal formula--a preclinical investigation using a rat model
    Ye Sun
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N T, Hong Kong, China
    Phytother Res 22:267-73. 2008
    ..In addition, microarray data of kidney tissue revealed that this herbal formula was able to down-regulate the expression of phase II drug metabolizing enzymes, similar to the effects of estrogens...
  87. ncbi Regional variations in microstructural properties of vertebral trabeculae with structural groups
    He Gong
    Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hong Kong, China
    Spine 31:24-32. 2006
    ..The data obtained may help to identify the most critical locations of fracture risks at an early stage and provide a microstructural basis for the repair and clinical treatment of vertebral fractures...
  88. ncbi Regional differences in trabecular BMD and micro-architecture of weight-bearing bone under habitual gait loading--a pQCT and microCT study in human cadavers
    Y M Lai
    Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, PR China
    Bone 37:274-82. 2005
    ..The findings from the correlation study also suggest that, apart from BMD, the micro-architecture may exhibit adaptation in response to such excessive loading...
  89. ncbi Total flavones of Hippophae rhamnoides promotes early restoration of ultimate stress of healing patellar tendon in a rat model
    S C Fu
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, China
    Med Eng Phys 27:313-21. 2005
    ..The results suggest that TFH may improve the ultimate stress of healing tendons at early stages, which implies possible earlier rehabilitation programme and better recovery...
  90. ncbi Osteopenia: a new prognostic factor of curve progression in adolescent idiopathic scoliosis
    V W Y Hung
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, 5/F, Clinical Sciences Building, Prince of Wales Hospital, Shatin, N.T. Hong Kong
    J Bone Joint Surg Am 87:2709-16. 2005
    ..The bone mineral density-inclusive predictive model may be used in treatment planning for patients with adolescent idiopathic scoliosis who are at high risk of curve progression...
  91. ncbi Gelatin microspheres containing TGF-beta3 enhance the chondrogenesis of mesenchymal stem cells in modified pellet culture
    Hongbin Fan
    Department of Orthopaedics and Traumatology, Xijing Hospital, Fourth Military Medical University, Xi an, China
    Biomacromolecules 9:927-34. 2008
    ..In conclusion, this modified pellet culture can provide an easy and effective way to construct the tissue-engineered cartilage in vitro...
  92. ncbi Tai Chi Chuan exercises in enhancing bone mineral density in active seniors
    Pauline Po Yee Lui
    CUHK WHO Collaborating Centre for Sports Medicine and Health Promotion, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
    Clin Sports Med 27:75-86, viii. 2008
    ..This article reviews the benefits of TCC for the prevention of osteoporosis and falls by retarding bone loss, improving neuromuscular coordination, and promoting general health...
  93. ncbi Regional variations in microstructural properties of vertebral trabeculae with aging
    He Gong
    Jockey Club Rehabilitation Engineering Center, The Hong Kong Polytechnic University, Hong Kong, China
    J Bone Miner Metab 23:174-80. 2005
    ..These data may help us to gain more insight into the mechanism of the occurrence of lumbar osteoporosis and the related regional fracture risks, and may provide a reference for better enhancement of fracture repair...
  94. ncbi Regional differences in cortical bone mineral density in the weight-bearing long bone shaft--a pQCT study
    Y M Lai
    Department of Optometry and Radiography, The Hong Kong Polytechnic University, Hong Kong SAR, PR China
    Bone 36:465-71. 2005
    ..Nevertheless, regional geometric adaptation in anterior cortical thickness might be adapted to accommodate for the reduced vBMD and to reduce the bending stress in this region...
  95. ncbi Postoperative programmed muscle tension augmented osteotendinous junction repair
    W Wang
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Hong Kong, China
    Int J Sports Med 28:691-6. 2007
    ..In conclusion, the postoperative programmed FES-induced muscle tension was favorable for acceleration of osteotendinous junction repair and therefore recommended for clinical trails in orthopedic sports medicine and rehabilitation...
  96. ncbi Epimedium-derived phytoestrogen exert beneficial effect on preventing steroid-associated osteonecrosis in rabbits with inhibition of both thrombosis and lipid-deposition
    G Zhang
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, PR China
    Bone 40:685-92. 2007
    ..This study tested the effect of Epimedium-derived phytoestrogen (PE) on preventing steroid-associated osteonecrosis (ON) in rabbit model...
  97. ncbi Staining intensity of individual osteons correlated with elastic properties and degrees of mineralization
    L Qin
    Musculoskeletal Research Laboratory, Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, N.T. Hong Kong
    J Bone Miner Metab 19:359-64. 2001
    ..713). The results of this study suggest that TB surface staining may be used as a simple method for indicating differences in stiffness and degree of mineralization in individual osteons in comparative histological studies...
  98. ncbi Persistent osteopenia in adolescent idiopathic scoliosis--longitudinal monitoring of bone mineral density until skeletal maturity
    J C Y Cheng
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Republic of China
    Stud Health Technol Inform 123:47-51. 2006
    ..Early detection and treatment of AIS-related osteopenia might help in maximizing peak bone mass during peripubertal growth that thereby minimizing risks of developing osteoporotic fractures later in life...
  99. ncbi Goats as an osteopenic animal model
    K S Leung
    Department of Orthopedics and Traumatology, The Chinese University of Hong Kong, Shatin
    J Bone Miner Res 16:2348-55. 2001
    ..439 and 0.581; p < 0.001 for both). In conclusion, this study showed that OVX plus a low-calcium diet could induce significant osteopenia and deterioration of mechanical properties of the cancellous bone in goats...
  100. ncbi A study of trabecular bones in ovariectomized goats with micro-computed tomography and peripheral quantitative computed tomography
    W S Siu
    Department of Orthopaedics and Traumatology, The Chinese University of Hong Kong, Shatin, NT, SAR
    Bone 35:21-6. 2004
    ..758, P< 0.001) and SMI (r = -0.697, P< 0.001). In conclusion, this was the first experimental study in goat model to show that OVX-induced bone loss in goats was attributed by deterioration of trabecular microarchitecture...
  101. ncbi Noncontact evaluation of articular cartilage degeneration using a novel ultrasound water jet indentation system
    M H Lu
    Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, P R China
    Ann Biomed Eng 37:164-75. 2009
    ....