Hiroshi Nishiura

Summary

Affiliation: The University of Hong Kong
Country: China

Publications

  1. pmc Sample size considerations for one-to-one animal transmission studies of the influenza A viruses
    Hiroshi Nishiura
    School of Public Health, The University of Hong Kong, Hong Kong SAR, China
    PLoS ONE 8:e55358. 2013
  2. pmc Estimating the transmission potential of supercritical processes based on the final size distribution of minor outbreaks
    Hiroshi Nishiura
    School of Public Health, The University of Hong Kong, Level 6, Core F, Cyberport 3, 100 Cyberport Road, Pokfulam, Hong Kong PRESTO, Japan Science and Technology Agency, Saitama 332 0012, Japan
    J Theor Biol 294:48-55. 2012
  3. pmc Theoretical basis to measure the impact of short-lasting control of an infectious disease on the epidemic peak
    Ryosuke Omori
    Department of Biology, Faculty of Sciences, Kyushu University, 6 10 1 Hakozaki, Higashi ku, Fukuoka 812 8581, Japan
    Theor Biol Med Model 8:2. 2011
  4. pmc Fever screening during the influenza (H1N1-2009) pandemic at Narita International Airport, Japan
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency, 4 1 8 Honcho, Kawaguchi, Saitama 332 0012, Japan
    BMC Infect Dis 11:111. 2011
  5. pmc Did modeling overestimate the transmission potential of pandemic (H1N1-2009)? Sample size estimation for post-epidemic seroepidemiological studies
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency, Saitama, Japan
    PLoS ONE 6:e17908. 2011
  6. pmc Real-time forecasting of an epidemic using a discrete time stochastic model: a case study of pandemic influenza (H1N1-2009)
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency, 4 1 8 Honcho, Kawaguchi, Saitama, Japan
    Biomed Eng Online 10:15. 2011
  7. pmc Infection fatality risk of the pandemic A(H1N1)2009 virus in Hong Kong
    Jessica Y Wong
    School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of China
    Am J Epidemiol 177:834-40. 2013
  8. pmc Heterogeneity in viral shedding among individuals with medically attended influenza A virus infection
    Lincoln L H Lau
    Infectious Disease Epidemiology Group, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
    J Infect Dis 207:1281-5. 2013
  9. pmc Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine
    Benjamin J Cowling
    School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Clin Infect Dis 54:1778-83. 2012
  10. pmc Household transmission of 2009 pandemic influenza A (H1N1): a systematic review and meta-analysis
    Lincoln L H Lau
    School of Public Health, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China
    Epidemiology 23:531-42. 2012

Collaborators

Detail Information

Publications35

  1. pmc Sample size considerations for one-to-one animal transmission studies of the influenza A viruses
    Hiroshi Nishiura
    School of Public Health, The University of Hong Kong, Hong Kong SAR, China
    PLoS ONE 8:e55358. 2013
    ..The analyses are illustrated on transmission studies of influenza A viruses in the ferret model...
  2. pmc Estimating the transmission potential of supercritical processes based on the final size distribution of minor outbreaks
    Hiroshi Nishiura
    School of Public Health, The University of Hong Kong, Level 6, Core F, Cyberport 3, 100 Cyberport Road, Pokfulam, Hong Kong PRESTO, Japan Science and Technology Agency, Saitama 332 0012, Japan
    J Theor Biol 294:48-55. 2012
    ....
  3. pmc Theoretical basis to measure the impact of short-lasting control of an infectious disease on the epidemic peak
    Ryosuke Omori
    Department of Biology, Faculty of Sciences, Kyushu University, 6 10 1 Hakozaki, Higashi ku, Fukuoka 812 8581, Japan
    Theor Biol Med Model 8:2. 2011
    ..As a first step to address this issue, we present a theoretical basis on which to assess the impact of an early intervention on the epidemic peak, employing a simple epidemic model...
  4. pmc Fever screening during the influenza (H1N1-2009) pandemic at Narita International Airport, Japan
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency, 4 1 8 Honcho, Kawaguchi, Saitama 332 0012, Japan
    BMC Infect Dis 11:111. 2011
    ..We aimed to retrospectively assess the feasibility of detecting influenza cases based on fever screening as a sole measure...
  5. pmc Did modeling overestimate the transmission potential of pandemic (H1N1-2009)? Sample size estimation for post-epidemic seroepidemiological studies
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency, Saitama, Japan
    PLoS ONE 6:e17908. 2011
    ..Seroepidemiological studies before and after the epidemic wave of H1N1-2009 are useful for estimating population attack rates with a potential to validate early estimates of the reproduction number, R, in modeling studies...
  6. pmc Real-time forecasting of an epidemic using a discrete time stochastic model: a case study of pandemic influenza (H1N1-2009)
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency, 4 1 8 Honcho, Kawaguchi, Saitama, Japan
    Biomed Eng Online 10:15. 2011
    ..Real-time forecasting of epidemics, especially those based on a likelihood-based approach, is understudied. This study aimed to develop a simple method that can be used for the real-time epidemic forecasting...
  7. pmc Infection fatality risk of the pandemic A(H1N1)2009 virus in Hong Kong
    Jessica Y Wong
    School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of China
    Am J Epidemiol 177:834-40. 2013
    ..Substantial variation in the age-specific infection fatality risk complicates comparison of the severity of different influenza strains...
  8. pmc Heterogeneity in viral shedding among individuals with medically attended influenza A virus infection
    Lincoln L H Lau
    Infectious Disease Epidemiology Group, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong, China
    J Infect Dis 207:1281-5. 2013
    ..Further investigation is required to correlate the substantial variations in viral shedding with heterogeneity in actual transmissibility...
  9. pmc Increased risk of noninfluenza respiratory virus infections associated with receipt of inactivated influenza vaccine
    Benjamin J Cowling
    School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Clin Infect Dis 54:1778-83. 2012
    ..40; 95% confidence interval: 1.31-14.8). Being protected against influenza, TIV recipients may lack temporary non-specific immunity that protected against other respiratory viruses...
  10. pmc Household transmission of 2009 pandemic influenza A (H1N1): a systematic review and meta-analysis
    Lincoln L H Lau
    School of Public Health, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China
    Epidemiology 23:531-42. 2012
    ..During the 2009 influenza A (H1N1) pandemic, household transmission studies were implemented to better understand the characteristics of the transmission of the novel virus in a confined setting...
  11. pmc The feasibility of age-specific travel restrictions during influenza pandemics
    Elson H Y Lam
    School of Public Health, The University of Hong Kong, Pokfulam, Hong Kong, People s Republic of China
    Theor Biol Med Model 8:44. 2011
    ..Influenza is, however, strongly influenced by age-dependent transmission dynamics, and the effectiveness of age-specific travel restrictions, such as the selective restriction of travel by children, has yet to be examined...
  12. pmc Age-dependent estimates of the epidemiological impact of pandemic influenza (H1N1-2009) in Japan
    Kenji Mizumoto
    School of Public Health, The University of Hong Kong, Level 6, Core F, Cyberport 3, 100 Cyberport Road, Pokfulam, Hong Kong
    Comput Math Methods Med 2013:637064. 2013
    ..A seroepidemiological study should be planned in advance of a pandemic...
  13. pmc Excess mortality associated with influenza A and B virus in Hong Kong, 1998-2009
    Peng Wu
    School of Public Health, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong Special Administrative Region, China
    J Infect Dis 206:1862-71. 2012
    ..Although deaths associated with laboratory-confirmed influenza virus infections are rare, the excess mortality burden of influenza estimated from statistical models may more reliably quantify the impact of influenza in a population...
  14. pmc Vaccination and clinical severity: is the effectiveness of contact tracing and case isolation hampered by past vaccination?
    Kenji Mizumoto
    School of Public Health, The University of Hong Kong, Level 6, Core F, Cyberport 3, 100 Cyberport Road, Pokfulam, Hong Kong
    Int J Environ Res Public Health 10:816-29. 2013
    ....
  15. pmc The epidemiological and public health research response to 2009 pandemic influenza A(H1N1): experiences from Hong Kong
    Peng Wu
    School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, China
    Influenza Other Respi Viruses 7:367-82. 2013
    ..The experiences of the research response in Hong Kong could provide a template for the research response to future emerging and reemerging disease epidemics...
  16. pmc Entry screening to delay local transmission of 2009 pandemic influenza A (H1N1)
    Benjamin J Cowling
    School of Public Health, The University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of China
    BMC Infect Dis 10:82. 2010
    ..After the WHO issued the global alert for 2009 pandemic influenza A (H1N1), many national health agencies began to screen travelers on entry in airports, ports and border crossings to try to delay local transmission...
  17. doi request reprint The virulence of pandemic influenza A (H1N1) 2009: an epidemiological perspective on the case-fatality ratio
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency, Saitama, Japan and Theoretical Epidemiology, University of Utrecht, Yalelaan 7, Utrecht, 3584 CL, The Netherlands
    Expert Rev Respir Med 4:329-38. 2010
    ....
  18. pmc Transmissibility of seasonal and pandemic influenza in a cohort of households in Hong Kong in 2009
    Brendan Klick
    School of Public Health, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China
    Epidemiology 22:793-6. 2011
    ..The household secondary attack proportion (SAP) is commonly used to measure the transmissibility of an infectious disease...
  19. pmc Modeling the obesity epidemic: social contagion and its implications for control
    Keisuke Ejima
    School of Public Health, The University of Hong Kong, Pokfulam, Hong Kong
    Theor Biol Med Model 10:17. 2013
    ....
  20. pmc Aerosol transmission is an important mode of influenza A virus spread
    Benjamin J Cowling
    School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong Special Administrative Region, Hong Kong, China
    Nat Commun 4:1935. 2013
    ..This implies that measures to reduce transmission by contact or large droplets may not be sufficient to control influenza A virus transmission in households...
  21. pmc How is vaccine effectiveness scaled by the transmission dynamics of interacting pathogen strains with cross-protective immunity?
    Ryosuke Omori
    School of Public Health, The University of Hong Kong, Hong Kong, Hong Kong SAR, People s Republic of China
    PLoS ONE 7:e50751. 2012
    ..e. vaccine and non-vaccine strains...
  22. pmc An analysis of national target groups for monovalent 2009 pandemic influenza vaccine and trivalent seasonal influenza vaccines in 2009-10 and 2010-11
    Sophia Ng
    School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, China
    BMC Infect Dis 11:230. 2011
    ..To understand differential patterns of national target groups for influenza vaccination before, during and after the 2009 influenza pandemic, we reviewed and analyzed the country-specific policies in the corresponding time periods...
  23. pmc Effectiveness of antiviral prophylaxis coupled with contact tracing in reducing the transmission of the influenza A (H1N1-2009): a systematic review
    Kenji Mizumoto
    School of Public Health, The University of Hong Kong, 100 Cyberport Road, Pokfulam, Hong Kong, China
    Theor Biol Med Model 10:4. 2013
    ....
  24. pmc How to interpret the transmissibility of novel influenza A(H7N9): an analysis of initial epidemiological data of human cases from China
    Hiroshi Nishiura
    School of Public Health, The University of Hong Kong, Level 6, Core F, Cyberport 3, Pokfulam, Hong Kong
    Theor Biol Med Model 10:30. 2013
    ..The presence of human-to-human transmission has not been demonstrated, but the absence of demonstration does not guarantee that there is no such transmission...
  25. doi request reprint Contact behaviour of children and parental employment behaviour during school closures against the pandemic influenza A (H1N1-2009) in Japan
    Kenji Mizumoto
    School of Public Health, University of Hong Kong, Hong Kong, China
    J Int Med Res 41:716-24. 2013
    ..To identify epidemiological determinants of the contact behaviour of children and their impact on parental employment, during school closures that took place over the course of the 2009 pandemic influenza (H1N1-2009) in Japan...
  26. pmc The impact of model building on the transmission dynamics under vaccination: observable (symptom-based) versus unobservable (contagiousness-dependent) approaches
    Keisuke Ejima
    School of Public Health, The University of Hong Kong, Hong Kong SAR, China
    PLoS ONE 8:e62062. 2013
    ..The present study aims to assess the impact of model building strategy on the epidemic threshold under vaccination...
  27. pmc Optimal design of intervention studies to prevent influenza in healthy cohorts
    Brendan Klick
    Infectious Disease Epidemiology Group, School of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People s Republic of China
    PLoS ONE 7:e35166. 2012
    ..Influenza infections and illnesses can be identified through a number of approaches with different costs and logistical requirements...
  28. pmc Pros and cons of estimating the reproduction number from early epidemic growth rate of influenza A (H1N1) 2009
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency, Honcho 4 1 8, Kawaguchi, Saitama, 332 0012, Japan
    Theor Biol Med Model 7:1. 2010
    ..The growth rate at the initial stage of the epidemic in Japan led to estimates for R in the range 2.0 to 2.6, capturing the intensity of the initial outbreak among school-age children in May 2009...
  29. doi request reprint Travel and age of influenza A (H1N1) 2009 virus infection
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency, Saitama, Japan
    J Travel Med 17:269-70. 2010
    ..01) reflecting age-specific travel patterns. Border controls should account for the high frequency of infection among adults...
  30. pmc Epidemiological determinants of successful vaccine development
    Hiroshi Nishiura
    1 School of Public Health, The University of Hong Kong, Level 6, Core F, Cyberport 3, 100 Cyberport Road, Pokfulam, Hong Kong SAR, China 2 PRESTO, Japan Science and Technology Agency, 4 1 8 Honcho Kawaguchi, Saitama, 332 0012 Japan
    Int J Med Sci 10:382-4. 2013
    ..Employing a logistic regression model, we demonstrate that a high affinity with blood and immune cells and pathogen interactions (e.g. interference) would be the risk factors of failure for vaccine development...
  31. doi request reprint Estimation of the incubation period of influenza A (H1N1-2009) among imported cases: addressing censoring using outbreak data at the origin of importation
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency, Saitama, Japan
    J Theor Biol 272:123-30. 2011
    ..When the data generating process is similar to that among imported cases, and when the incubation period is close to or shorter than the length of exposure, accounting for these aspects is critical for long exposure times...
  32. pmc Assortativity and the Probability of Epidemic Extinction: A Case Study of Pandemic Influenza A (H1N1-2009)
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency, Saitama 332 0012, Japan
    Interdiscip Perspect Infect Dis 2011:194507. 2011
    ....
  33. doi request reprint Time variations in the generation time of an infectious disease: implications for sampling to appropriately quantify transmission potential
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency JST, 4 1 8 Honcho Kawaguchi, Saitama 332 0012, Japan
    Math Biosci Eng 7:851-69. 2010
    ..Mathematical properties of the generation time distribution in a heterogeneously mixing population need to be clarified further...
  34. ncbi request reprint [A robust statistic AC₁ for assessing inter-observer agreement in reliability studies]
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency
    Nihon Hoshasen Gijutsu Gakkai Zasshi 66:1485-91. 2010
    ..AC₁ adjusts chance agreement more appropriately than kappa and is regarded as a more useful measurement for assessing inter-observer agreement, especially when prevalence is small...
  35. pmc Correcting the actual reproduction number: a simple method to estimate R(0) from early epidemic growth data
    Hiroshi Nishiura
    PRESTO, Japan Science and Technology Agency, Saitama, 332 0012, Japan
    Int J Environ Res Public Health 7:291-302. 2010
    ..60 to 3.74, consistent with those based on the Euler-Lotka equation. The method also permits calculating the expected value of R(0) using a spreadsheet...