Pak Cheng Ng

Summary

Affiliation: The Chinese University of Hong Kong
Country: China

Publications

  1. ncbi request reprint Repeated courses of antenatal corticosteroids: is it justified?
    Tse N Leung
    Department of Obstetrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Acta Obstet Gynecol Scand 82:589-96. 2003
  2. ncbi request reprint Early prediction of sepsis-induced disseminated intravascular coagulation with interleukin-10, interleukin-6, and RANTES in preterm infants
    Pak C Ng
    Department of Pediatrics, Center of Epidemiology and Biostatistics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong Special Administrative Region
    Clin Chem 52:1181-9. 2006
  3. doi request reprint Use of oral erythromycin for the treatment of gastrointestinal dysmotility in preterm infants
    Pak C Ng
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, SAR, China
    Neonatology 95:97-104. 2009
  4. ncbi request reprint Promoting effects of serotonin on hematopoiesis: ex vivo expansion of cord blood CD34+ stem/progenitor cells, proliferation of bone marrow stromal cells, and antiapoptosis
    Mo Yang
    Li Ka Shing Institute of Health Sciences, Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, China
    Stem Cells 25:1800-6. 2007
  5. ncbi request reprint Probable intrafamilial transmission of coxsackievirus b3 with vertical transmission, severe early-onset neonatal hepatitis, and prolonged viral RNA shedding
    Ling Ling Cheng
    Department of Pediatrics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China
    Pediatrics 118:e929-33. 2006
  6. pmc Immunoregulatory protein profiles of necrotizing enterocolitis versus spontaneous intestinal perforation in preterm infants
    Kathy Yuen Yee Chan
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    PLoS ONE 7:e36977. 2012
  7. doi request reprint Biomarkers of necrotising enterocolitis
    Pak Cheung Ng
    Department of Paediatrics, 6th Floor, Clinical Sciences Building, Prince of Wales Hospital, Shatin, N T, Hong Kong Electronic address
    Semin Fetal Neonatal Med 19:33-8. 2014
  8. doi request reprint Expression profile of cord blood neutrophils and dysregulation of HSPA1A and OLR1 upon challenge by bacterial peptidoglycan
    Oi Ning Fong
    2 Level 6, Clinical Sciences Building, Prince of Wales Hospital, Shatin, N T, Hong Kong
    J Leukoc Biol 95:169-78. 2014
  9. pmc Outcome of children with life-threatening asthma necessitating pediatric intensive care
    Kam Lun Hon
    Department of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong
    Ital J Pediatr 36:47. 2010
  10. ncbi request reprint Biomarkers for prediction and diagnosis of necrotizing enterocolitis
    Pak C Ng
    Department of Paediatrics, The Chinese University of Hong Kong, Shatin NT, Hong Kong SAR, The People s Republic of China
    Clin Perinatol 40:149-59. 2013

Collaborators

Detail Information

Publications81

  1. ncbi request reprint Repeated courses of antenatal corticosteroids: is it justified?
    Tse N Leung
    Department of Obstetrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Acta Obstet Gynecol Scand 82:589-96. 2003
    ..This review aims to discuss current evidence on the effectiveness and safety of repeated courses of antenatal corticosteroids...
  2. ncbi request reprint Early prediction of sepsis-induced disseminated intravascular coagulation with interleukin-10, interleukin-6, and RANTES in preterm infants
    Pak C Ng
    Department of Pediatrics, Center of Epidemiology and Biostatistics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong Special Administrative Region
    Clin Chem 52:1181-9. 2006
    ..We investigated the immunologic profiles of preterm infants with sepsis, using chemokine and cytokine measurements to predict the development of sepsis-induced DIC at the onset of infection...
  3. doi request reprint Use of oral erythromycin for the treatment of gastrointestinal dysmotility in preterm infants
    Pak C Ng
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, SAR, China
    Neonatology 95:97-104. 2009
    ..Nonetheless, as long-term outcomes have not been fully evaluated, neonatologists should use this treatment cautiously and selectively in preterm infants with moderately severe GI dysmotility...
  4. ncbi request reprint Promoting effects of serotonin on hematopoiesis: ex vivo expansion of cord blood CD34+ stem/progenitor cells, proliferation of bone marrow stromal cells, and antiapoptosis
    Mo Yang
    Li Ka Shing Institute of Health Sciences, Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, China
    Stem Cells 25:1800-6. 2007
    ..Serotonin could be developed for clinical ex vivo expansion of hematopoietic stem cells for transplantation. Disclosure of potential conflicts of interest is found at the end of this article...
  5. ncbi request reprint Probable intrafamilial transmission of coxsackievirus b3 with vertical transmission, severe early-onset neonatal hepatitis, and prolonged viral RNA shedding
    Ling Ling Cheng
    Department of Pediatrics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China
    Pediatrics 118:e929-33. 2006
    ..We show that even mild household infections may have potentially serious consequences for pregnant women and their infants...
  6. pmc Immunoregulatory protein profiles of necrotizing enterocolitis versus spontaneous intestinal perforation in preterm infants
    Kathy Yuen Yee Chan
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    PLoS ONE 7:e36977. 2012
    ..Such exaggerated immunologic responses may account for the high morbidity and mortality in NEC compared with SIP patients...
  7. doi request reprint Biomarkers of necrotising enterocolitis
    Pak Cheung Ng
    Department of Paediatrics, 6th Floor, Clinical Sciences Building, Prince of Wales Hospital, Shatin, N T, Hong Kong Electronic address
    Semin Fetal Neonatal Med 19:33-8. 2014
    ..A stringent protocol for biomarker discovery is revealed so that investigators can consider this methodology as a reference for future discovery of organ-specific and/or disease-specific biomarkers for preterm infants. ..
  8. doi request reprint Expression profile of cord blood neutrophils and dysregulation of HSPA1A and OLR1 upon challenge by bacterial peptidoglycan
    Oi Ning Fong
    2 Level 6, Clinical Sciences Building, Prince of Wales Hospital, Shatin, N T, Hong Kong
    J Leukoc Biol 95:169-78. 2014
    ....
  9. pmc Outcome of children with life-threatening asthma necessitating pediatric intensive care
    Kam Lun Hon
    Department of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong
    Ital J Pediatr 36:47. 2010
    ..To report the outcome of children with life-threatening asthma (LTA) admitted to a university Pediatric Intensive Care Unit (PICU)...
  10. ncbi request reprint Biomarkers for prediction and diagnosis of necrotizing enterocolitis
    Pak C Ng
    Department of Paediatrics, The Chinese University of Hong Kong, Shatin NT, Hong Kong SAR, The People s Republic of China
    Clin Perinatol 40:149-59. 2013
    ....
  11. doi request reprint Biomarkers in neonatology: the next generation of tests
    Pak C Ng
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, SAR, China
    Neonatology 102:145-51. 2012
    ..This article aims to introduce the concept of the next generation of biomarkers to practising neonatal clinicians, and, hopefully, to integrate basic science research into day-to-day clinical practice in the future...
  12. pmc Influenza or not influenza: analysis of a case of high fever that happened 2000 years ago in Biblical time
    Kam L E Hon
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    Virol J 7:169. 2010
    ..Infectious diseases continue to be a threat to humanity, and influenza has been with us since the dawn of human history. We analysed a case of high fever that happened 2000 years ago in Biblical time and discussed possible etiologies...
  13. pmc Waist circumference and waist-to-height ratio of Hong Kong Chinese children
    Rita Y T Sung
    Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, The People s Republic of China
    BMC Public Health 8:324. 2008
    ..We aim to provide age- and sex-specific reference values for WC and WHTR in Hong Kong Chinese children...
  14. ncbi request reprint Persistent Staphylococcus capitis septicemia in a preterm infant
    Pak C Ng
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Pediatr Infect Dis J 25:652-4. 2006
    ..Rifampin and linezolid should be considered as alternative antimicrobial agents when glycopeptides fail to eradicate Gram-positive pathogens from the host...
  15. ncbi request reprint High-dose oral erythromycin decreased the incidence of parenteral nutrition-associated cholestasis in preterm infants
    Pak C Ng
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Gastroenterology 132:1726-39. 2007
    ..Two secondary end points, including the time to achieve full enteral feeding and the duration of parenteral nutrition, were also evaluated...
  16. ncbi request reprint Diagnostic markers for neonatal sepsis
    Pak C Ng
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Curr Opin Pediatr 18:125-31. 2006
    ..To review the current evidence on the use of infection markers for diagnostic evaluation of sepsis in neonates...
  17. ncbi request reprint A double-blind, randomized, controlled study of a "stress dose" of hydrocortisone for rescue treatment of refractory hypotension in preterm infants
    Pak C Ng
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Pediatrics 117:367-75. 2006
    ..We hypothesized that significantly more VLBW infants who were receiving dopamine > or =10 microg/kg per min could wean off vasopressor support 72 hours after treatment with hydrocortisone...
  18. ncbi request reprint Resistin in preterm and term newborns: relation to anthropometry, leptin, and insulin
    Pak Cheng Ng
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N T
    Pediatr Res 58:725-30. 2005
    ..Infants who were born vaginally had significantly higher plasma resistin levels, suggesting that this hormone might also be associated with stress or inflammation induced by the birth process...
  19. ncbi request reprint Quantitative measurement of monocyte HLA-DR expression in the identification of early-onset neonatal infection
    Pak Cheung Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong, SAR, China
    Biol Neonate 89:75-81. 2006
    ..This study aimed to evaluate the diagnostic utilities of monocyte HLA-DR as an infection marker in the identification of early-onset clinical infection and pneumonia in newborn infants...
  20. ncbi request reprint Ghrelin in preterm and term newborns: relation to anthropometry, leptin and insulin
    Pak C Ng
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N T, Hong Kong
    Clin Endocrinol (Oxf) 63:217-22. 2005
    ....
  21. ncbi request reprint IP-10 is an early diagnostic marker for identification of late-onset bacterial infection in preterm infants
    Pak C Ng
    Department of Pediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, China
    Pediatr Res 61:93-8. 2007
    ..We conclude that preterm infants have the ability to induce a robust chemokine and cytokine response during sepsis, and IP-10 is a sensitive early marker of infection...
  22. doi request reprint A longitudinal study to establish the normative value and to evaluate perinatal factors affecting intraocular pressure in preterm infants
    Pak Cheung Ng
    Department of Pediatric, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Invest Ophthalmol Vis Sci 49:87-92. 2008
    ..To establish a normative range of intraocular pressure (IOP) in preterm infants and to identify important perinatal factors that could affect the IOP during the early weeks of neonatal life...
  23. doi request reprint A prospective longitudinal study to estimate the "adjusted cortisol percentile" in preterm infants
    Pak C Ng
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, New Territories, Hong Kong
    Pediatr Res 69:511-6. 2011
    ..sta.cuhk.edu.hk/pswong/ACortP.html) to calculate the adjusted cortisol percentile, which could potentially improve the interpretation of circulating cortisol in different clinical situations...
  24. doi request reprint Effect of stress on the hypothalamic-pituitary-adrenal axis in the fetus and newborn
    Pak Cheung Ng
    Department of Pediatrics, Chinese University of Hong Kong, Hong Kong, China
    J Pediatr 158:e41-3. 2011
    ..Chronic intrauterine hypoxemia can up-regulate the setpoint of the HPA axis and augments adrenal steroidogenic production, resulting in sustained elevation of circulating cortisol levels...
  25. doi request reprint Biomarkers for late-onset neonatal sepsis: cytokines and beyond
    Pak C Ng
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Clin Perinatol 37:599-610. 2010
    ....
  26. ncbi request reprint Biomarkers in neonatal infection
    Hugh S Lam
    The Chinese University of Hong Kong, Department of Paediatrics, 6 F Clinical Sciences Building, Prince of Wales Hospital, Sha Tin, New Territories, Hong Kong
    Biomark Med 1:133-43. 2007
    ..The application of these biomarkers to derive prognostic information useful to neonatal clinicians will also be considered...
  27. ncbi request reprint Is there a "normal" range of serum cortisol concentration for preterm infants?
    Pak C Ng
    Department of Pediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong
    Pediatrics 122:873-5. 2008
  28. doi request reprint Suppression and recovery of the hypothalamic function after high-dose corticosteroid treatment in preterm infants
    P C Ng
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, SAR, China
    Neonatology 94:170-5. 2008
    ..Although the suppression and recovery of pituitary-adrenal response had been assessed after corticosteroid treatment in very low birth weight infants, its effect on hypothalamic function has not been longitudinally monitored...
  29. doi request reprint Transient increase in intraocular pressure during a dose-tapering regime of systemic dexamethasone in preterm infants
    Pak C Ng
    Department of Pediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, China
    Ophthalmology 115:e7-14. 2008
    ..To determine the intraocular pressure (IOP) profile during and after systemic dexamethasone treatment in preterm very low birth weight (VLBW; <1500 g) infants...
  30. pmc Chemokine response in children with SARS
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories
    Arch Dis Child 90:422-3. 2005
    ..High circulating IP-10 levels could facilitate viral clearance and might play a role in assisting the recovery of the patients...
  31. ncbi request reprint Plasma ghrelin and resistin concentrations are suppressed in infants of insulin-dependent diabetic mothers
    P C Ng
    Department of Pediatrics, Level 6, Clinical Sciences Building, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, N T, Hong Kong
    J Clin Endocrinol Metab 89:5563-8. 2004
    ....
  32. ncbi request reprint Changes in serum leptin concentration after corticosteroid treatment in preterm infants
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT
    Acta Paediatr 91:684-90. 2002
    ..05 and p < 0.001 for ACTH and cortisol, respectively). In contrast, serum leptin and insulin at weeks 5 (T(wk-5)) and 7 (T(wk-7)) did not differ significantly from their respective levels at week 2 (T(wk-2)) in the non-treatment group...
  33. pmc Early pituitary-adrenal response and respiratory outcomes in preterm infants
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT
    Arch Dis Child Fetal Neonatal Ed 89:F127-30. 2004
    ....
  34. pmc Transient adrenocortical insufficiency of prematurity and systemic hypotension in very low birthweight infants
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT
    Arch Dis Child Fetal Neonatal Ed 89:F119-26. 2004
    ....
  35. pmc Randomised controlled study of oral erythromycin for treatment of gastrointestinal dysmotility in preterm infants
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT
    Arch Dis Child Fetal Neonatal Ed 84:F177-82. 2001
    ..To evaluate the effectiveness of oral erythromycin as a prokinetic agent for the treatment of moderately severe gastrointestinal dysmotility in preterm very low birthweight infants...
  36. ncbi request reprint Reference ranges and factors affecting the human corticotropin-releasing hormone test in preterm, very low birth weight infants
    P C Ng
    Department of Pediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, N T, Hong Kong
    J Clin Endocrinol Metab 87:4621-8. 2002
    ....
  37. ncbi request reprint Inflammatory cytokine profile in children with severe acute respiratory syndrome
    Pak C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Pediatrics 113:e7-14. 2004
    ....
  38. pmc Anti B cell targeted immunotherapy for treatment of refractory autoimmune haemolytic anaemia in a young infant
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong
    Arch Dis Child 88:337-9. 2003
    ..Paediatricians should be aware of this useful therapeutic tool for treatment of refractory autoimmune haemolytic anaemia and balance its use against the risk of potential life threatening infection...
  39. pmc Proinflammatory and anti-inflammatory cytokine responses in preterm infants with systemic infections
    P C Ng
    Department of Paediatrics, Level 6, Clinical Sciences Building, Prince of Wales Hospital, Shatin, NT, Hong Kong
    Arch Dis Child Fetal Neonatal Ed 88:F209-13. 2003
    ..A prospective study to investigate the pattern of proinflammatory and anti-inflammatory cytokine responses in preterm infants with systemic infection...
  40. pmc Infection control for SARS in a tertiary neonatal centre
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, China
    Arch Dis Child Fetal Neonatal Ed 88:F405-9. 2003
    ..We hope this information is useful in helping other units to formulate their own infection control plans according to their own unit configuration and clinical needs...
  41. ncbi request reprint Neutrophil CD64 expression: a sensitive diagnostic marker for late-onset nosocomial infection in very low birthweight infants
    Pak C Ng
    Department of Pediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT, PR China
    Pediatr Res 51:296-303. 2002
    ..The quantitative flow cytometric analysis applied in this study could be developed into a routine clinical test with high comparability and reproducibility across different laboratories...
  42. pmc Combined use of alcohol hand rub and gloves reduces the incidence of late onset infection in very low birthweight infants
    P C Ng
    Level 6, Clinical Sciences Building, Prince of Wales Hospital, Shatin, NT, Hong Kong
    Arch Dis Child Fetal Neonatal Ed 89:F336-40. 2004
    ....
  43. ncbi request reprint Severe congenital absence of skin in a preterm infant
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin
    J Paediatr Child Health 35:306-8. 1999
    ..The prognosis in aplasia cutis congenita is determined by the underlying associated anomalies, the severity of skin lesions and, in our case, the maturity of the infant who died from complications of prematurity...
  44. ncbi request reprint Central nervous system candidiasis in preterm infants: limited value of biochemical markers for diagnosis
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories
    J Paediatr Child Health 36:509-10. 2000
    ..Clinicians should be aware of the limitation of biochemical infection markers so that diagnosis and treatment of fungal infection will not be delayed...
  45. ncbi request reprint Neutrophil CD64 is a sensitive diagnostic marker for early-onset neonatal infection
    Pak C Ng
    Department of Pediatrics, Level 6, Clinical Sciences Building, Prince of Wales Hospital, Shatin, NT, Hong Kong
    Pediatr Res 56:796-803. 2004
    ....
  46. pmc Leptin and metabolic hormones in infants of diabetic mothers
    P C Ng
    Department of Paediatrics, Level 6, Clinical Science Building, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, NT, Hong Kong
    Arch Dis Child Fetal Neonatal Ed 83:F193-7. 2000
    ....
  47. ncbi request reprint Early pituitary-adrenal responses and retinopathy of prematurity in very low birth weight infants
    Pak Cheung Ng
    Department of Pediatrics, Level 6, Clinical Sciences Building, Prince of Wales Hospital, Shatin, N T, Hong Kong
    Pediatr Res 55:114-9. 2004
    ..Low birth weight and prolonged oxygen exposure are likely to be important factors that influence the degree of damage inflicted on the retina...
  48. pmc Hepatic iron storage in very low birthweight infants after multiple blood transfusions
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong
    Arch Dis Child Fetal Neonatal Ed 84:F101-5. 2001
    ..To investigate the effect of multiple blood transfusions on hepatic iron storage in preterm, very low birthweight (VLBW) infants...
  49. ncbi request reprint Effects of inhaled corticosteroids on systemic blood pressure in preterm infants
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong
    Biol Neonate 86:201-6. 2004
    ....
  50. pmc Refractory hypotension in preterm infants with adrenocortical insufficiency
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong
    Arch Dis Child Fetal Neonatal Ed 84:F122-4. 2001
    ..Corticosteroid treatment should be considered and could be life saving in severely hypotensive preterm infants who do not respond to conventional treatment with volume expanders and inotropes...
  51. ncbi request reprint Changes of leptin and metabolic hormones in preterm infants: a longitudinal study in early postnatal life
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, NT Hong Kong
    Clin Endocrinol (Oxf) 54:673-80. 2001
    ..We also postulate that a rapid increase in body weight and body mass index in the first few weeks of life may be associated with a corresponding increase in serum leptin if the 'adipoinsular axis' is active at this stage...
  52. pmc Changes in markers of bone metabolism during dexamethasone treatment for chronic lung disease in preterm infants
    P C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong
    Arch Dis Child Fetal Neonatal Ed 86:F49-54. 2002
    ..To characterise the change in serum and urinary bone markers in the early postnatal period, and to assess the effect of systemic corticosteroid on bone metabolism in preterm infants...
  53. ncbi request reprint Infants born to mothers with severe acute respiratory syndrome
    Chi C Shek
    Department of Paediatrics and Adolescent Medicine, Princess Margaret Hospital, Lai Chi Kok, New Territories, Hong Kong
    Pediatrics 112:e254. 2003
    ..This case series is the first report to describe the clinical course of the first cohort of liveborn infants born to pregnant women with SARS...
  54. doi request reprint Leukotriene receptor antagonist in the treatment of childhood allergic rhinitis--a randomized placebo-controlled study
    Albert M Li
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Pediatr Pulmonol 44:1085-92. 2009
    ..The effects of 16-week treatment of LTRA in addition to fexofenadine (FEX) on persistent AR in asthmatic children were examined...
  55. doi request reprint Prevalence and risk factors of habitual snoring in primary school children
    Albert M Li
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Chest 138:519-27. 2010
    ..Our study aimed to determine the prevalence of habitual snoring (HS) in primary school children and to evaluate the diurnal symptoms and conditions that may be associated with it...
  56. doi request reprint Unusual loss of body hair in childhood: Trichotillomania or alopecia
    Kam Lun Ellis Hon
    Department of Paediatrics, Chinese University of Hong Kong, 6 F, Clinical Sciences Building, Prince of Wales Hospital, Shatin, Hong Kong Special Administrative Region, People s Republic of China
    Adv Ther 25:380-7. 2008
    ..These cases serve to illustrate the principles of management of children with unusual patterns of hair loss...
  57. pmc Renal screening in children after exposure to low dose melamine in Hong Kong: cross sectional study
    Hugh S Lam
    Department of Paediatrics, The Chinese University of Hong Kong
    BMJ 337:a2991. 2008
    ..To investigate the renal outcomes of children after exposure to low dose melamine in Hong Kong...
  58. doi request reprint Adipokines in children with obstructive sleep apnea and the effects of treatment
    Albert M Li
    Department of Pediatrics, Prince of Wales Hospital and Shatin Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Chest 137:529-35. 2010
    ..The objective of this study was to evaluate circulating adipokines concentration in children with and without obstructive sleep apnea (OSA) and to determine the effects of treatment of OSA on their plasma concentration...
  59. ncbi request reprint Bronchodilator effect of salbutamol from two different spacer devices
    Albert M Li
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong
    Pediatr Pulmonol 41:326-30. 2006
    ..0-8.0) and 9.0 (IQR 8.0-10.0) (p < 0.0005), respectively. In conclusion, comparable clinical efficacy was found for V and VS with respect to changes in FEV1 after salbutamol. Patients also showed a strong preference for the new device...
  60. ncbi request reprint C-reactive protein in children with obstructive sleep apnea and the effects of treatment
    Albert M Li
    Department of Pediatrics, Prince of Wales and Shatin Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    Pediatr Pulmonol 43:34-40. 2008
    ..To evaluate C-reactive protein (CRP) concentration in children with OSA and to determine the effects of treatment for OSA on its serum concentration...
  61. ncbi request reprint Fetal methylmercury exposure as measured by cord blood mercury concentrations in a mother-infant cohort in Hong Kong
    Tai F Fok
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong
    Environ Int 33:84-92. 2007
    ..In this population, pregnant women should choose freshwater over marine fish and limit fish consumption...
  62. ncbi request reprint Standard reference for the six-minute-walk test in healthy children aged 7 to 16 years
    Albert M Li
    Department of Pediatrics, and Centre for Epidemiology and Biostatistics, 6th Floor, Clinical Sciences Building, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Am J Respir Crit Care Med 176:174-80. 2007
    ..We have previously reported that the six-minute-walk test (6MWT) is a reliable and valid functional test for assessing exercise tolerance and endurance. There is a lack of pediatric standard reference for the 6MWT...
  63. doi request reprint Rapid identification and differentiation of Gram-negative and Gram-positive bacterial bloodstream infections by quantitative polymerase chain reaction in preterm infants
    Kathy Y Y Chan
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N T, Hong Kong
    Crit Care Med 37:2441-7. 2009
    ..To evaluate the usefulness of the Gram-specific probe-based quantitative polymerase chain reaction test for rapid detection and differentiation of Gram-negative and Gram-positive bacterial bloodstream infection in preterm infants...
  64. doi request reprint Rescue treatment of infants with intestinal failure and parenteral nutrition-associated cholestasis (PNAC) using a parenteral fish-oil-based lipid
    Hon M Cheung
    Department of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Level 6, Clinical Sciences Building, Shatin, N T, Hong Kong
    Clin Nutr 28:209-12. 2009
    ..Our findings suggest that fish-oil-based parenteral lipid emulsion may contribute to effective treatment of PNAC in selected patients, which should be further evaluated in randomized controlled trials...
  65. ncbi request reprint SARS in newborns and children
    Pak C Ng
    Department of Paediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong pakcheungngcuhk edu hk
    Biol Neonate 85:293-8. 2004
    ..This review describes the current understanding of the clinical manifestations, diagnostic tests, immunological profiles, patient management and outcomes of SARS-CoV infection in the paediatric population...
  66. ncbi request reprint Clinical, virologic and immunologic profiles of a young infant with severe acute respiratory syndrome
    Frankie W T Cheng
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N T
    Pediatr Infect Dis J 24:567-8. 2005
    ..Ribavirin failed to inhibit SARS coronavirus (SARS-CoV) replication. One-step real time reverse transcription-polymerase chain reaction for plasma SARS-CoV RNA quantification was useful for early diagnosis and monitoring viremia...
  67. doi request reprint Biochemical markers of neonatal sepsis
    Hugh S Lam
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Pathology 40:141-8. 2008
    ..The advent of flow cytometry and molecular techniques have made crucial contributions to the field and promise to further improve the diagnostic accuracy and clinical management of infected infants...
  68. ncbi request reprint Rapid control of norovirus gastroenteritis outbreak in an acute paediatric ward
    Frankie W T Cheng
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Acta Paediatr 95:581-6. 2006
    ..To provide a practical action plan for effective infection control of norovirus outbreak in acute paediatric wards...
  69. ncbi request reprint Ex utero intrapartum treatment (EXIT) for congenital giant ranula
    Dorothy F Y Chan
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Acta Paediatr 95:1303-5. 2006
    ....
  70. ncbi request reprint Are your hands clean enough for point-of-care electrolyte analysis?
    Hugh S Lam
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Pathology 37:299-304. 2005
    ..To investigate clinically significant analytical interference in point-of-care electrolyte analysis caused by contamination of blood specimens with hand disinfectant...
  71. doi request reprint Successful treatment of multiple subdural empyemata caused by Mycoplasma hominis in a newborn
    Josephine S C Chong
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Neonatology 95:179-82. 2009
    ..This report illustrates the clinical presentation of this unusual infection and the crucial role of neurosurgical intervention and specific antimicrobial therapy for its successful management...
  72. ncbi request reprint Congenital cervical fibrosacroma with hydrops fetalis
    Po Mui Lam
    Department of Obstetrics and Gynecology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China
    Acta Obstet Gynecol Scand 83:773-6. 2004
  73. ncbi request reprint Small peptide analogue of SDF-1alpha supports survival of cord blood CD34+ cells in synergy with other cytokines and enhances their ex vivo expansion and engraftment into nonobese diabetic/severe combined immunodeficient mice
    Karen Li
    Department of Paediatrics, The Chinese University of Hong Kong, 6th Floor, Clinical Sciences Block, Prince of Wales Hospital, Shatin, NT, Hong Kong, People s Republic of China
    Stem Cells 24:55-64. 2006
    ..The small peptide analogue of SDF-1 could be developed for ex vivo expansion and improving engraftment of cord blood transplantation...
  74. doi request reprint Oscillometrically measured blood pressure in Hong Kong Chinese children and associations with anthropometric parameters
    Rita Y T Sung
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    J Hypertens 26:678-84. 2008
    ..BP standards for Chinese children have been based on sphygmomanometry and have not provided height-related or weight-related BP percentiles...
  75. ncbi request reprint Risk of vitamin A toxicity from candy-like chewable vitamin supplements for children
    Hugh Simon Lam
    Department of Pediatrics, Prince of Wales Hospital, Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong
    Pediatrics 118:820-4. 2006
    ..Parents should be warned about the dangers of excessive vitamin consumption. Clinicians should be aware of the late peak in serum retinol concentrations, which may lead to late complications of vitamin A overdose...
  76. ncbi request reprint The plant mannose-binding lectin NTL preserves cord blood haematopoietic stem/progenitor cells in long-term culture and enhances their ex vivo expansion
    Karen Li
    Li Ka Shing Institute of Health Sciences, Department of Paediatrics, The Chinese Uinversity of Hong Kong, Hong Kong, China
    Br J Haematol 140:90-8. 2008
    ....
  77. ncbi request reprint Ribavirin for SARS in children
    Wai Tsoi Frankie Cheng
    Department of Pediatrics, 6 F, Clinical Sciences Building, Prince of Wales Hospital, Shatin, Hong Kong
    Clin Pediatr (Phila) 43:193-6. 2004
  78. ncbi request reprint Arsenic trioxide mediates intrinsic and extrinsic pathways of apoptosis and cell cycle arrest in acute megakaryocytic leukemia
    Hubert Kin Bong Lam
    Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, P R China
    Int J Oncol 27:537-45. 2005
    ..The multiple-signaling mechanism of ATO warrants it a potential agent to incorporate in the treatment regimen of AMKL...
  79. ncbi request reprint Multiplex primer extension reaction screening and oxidative challenge of glucose-6-phosphate dehydrogenase mutants in hemizygous and heterozygous subjects
    Chun Hay Ko
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, SAR, China
    Blood Cells Mol Dis 37:21-6. 2006
    ..Our data demonstrated the potentials of the MPER assay for characterization of G6PD deficiency and other genetic diseases...
  80. ncbi request reprint Thrombopoietin protects against in vitro and in vivo cardiotoxicity induced by doxorubicin
    Karen Li
    Department of Pediatrics, The Chinese University of Hong Kong, Shatin, NT, Hong Kong
    Circulation 113:2211-20. 2006
    ..Our hypothesis is that the hematopoietic/megakaryocytopoietic growth factor thrombopoietin (TPO) protects against DOX-induced cardiotoxicity and might involve antiapoptotic mechanism exerted on cardiomyocytes...
  81. doi request reprint Premorbid factors and outcome associated with respiratory virus infections in a pediatric intensive care unit
    Kam Lun Hon
    Department of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China
    Pediatr Pulmonol 43:275-80. 2008
    ..The purpose of this study was to report the clinical features and outcome of all children with a laboratory proven diagnosis of respiratory virus infection admitted to a university Pediatric Intensive Care Unit (PICU)...