Wing Yee Lui

Summary

Affiliation: The University of Hong Kong
Country: China

Publications

  1. pmc Transforming growth factor-β1 (TGF-β1) regulates cell junction restructuring via Smad-mediated repression and clathrin-mediated endocytosis of nectin-like molecule 2 (Necl-2)
    Ying Gao
    School of Biological Sciences, The University of Hong Kong, Hong Kong, PR China
    PLoS ONE 8:e64316. 2013
  2. ncbi request reprint Transcriptional regulation of cell adhesion at the blood-testis barrier and spermatogenesis in the testis
    Wing Yee Lui
    School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China
    Adv Exp Med Biol 763:281-94. 2012
  3. ncbi request reprint Nectin-2 expression in testicular cells is controlled via the functional cooperation between transcription factors of the Sp1, CREB, and AP-1 families
    Wing Yee Lui
    Department of Zoology, The University of Hong Kong, Pokfulam, Hong Kong
    J Cell Physiol 207:144-57. 2006
  4. ncbi request reprint Regulation of junction dynamics in the testis--transcriptional and post-translational regulations of cell junction proteins
    Wing Yee Lui
    Department of Zoology, The University of Hong Kong, Pokfulam, Hong Kong, China
    Mol Cell Endocrinol 250:25-35. 2006
  5. ncbi request reprint Expression of CLMP, a novel tight junction protein, is mediated via the interaction of GATA with the Kruppel family proteins, KLF4 and Sp1, in mouse TM4 Sertoli cells
    Kit Ling Sze
    School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong
    J Cell Physiol 214:334-44. 2008
  6. ncbi request reprint Mechanisms of reorganization of cell-cell junctions in the testis
    Wing Yee Lui
    School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong
    Front Biosci 13:6775-86. 2008
  7. pmc Regulation of cell junction dynamics by cytokines in the testis: a molecular and biochemical perspective
    Wing Yee Lui
    School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong
    Cytokine Growth Factor Rev 18:299-311. 2007
  8. ncbi request reprint Dual transcriptional control of claudin-11 via an overlapping GATA/NF-Y motif: positive regulation through the interaction of GATA, NF-YA, and CREB and negative regulation through the interaction of Smad, HDAC1, and mSin3A
    Wing Yee Lui
    Department of Zoology, The University of Hong Kong, Pokfulam, Hong Kong
    J Cell Physiol 211:638-48. 2007
  9. doi request reprint Opposite effects of interleukin-1alpha and transforming growth factor-beta2 induce stage-specific regulation of junctional adhesion molecule-B gene in Sertoli cells
    Yang Wang
    Division of Endocrinology, School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong
    Endocrinology 150:2404-12. 2009
  10. doi request reprint Transforming growth factor-β1 attenuates junctional adhesion molecule-A and contributes to breast cancer cell invasion
    Yang Wang
    School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong
    Eur J Cancer 48:3475-87. 2012

Collaborators

Detail Information

Publications14

  1. pmc Transforming growth factor-β1 (TGF-β1) regulates cell junction restructuring via Smad-mediated repression and clathrin-mediated endocytosis of nectin-like molecule 2 (Necl-2)
    Ying Gao
    School of Biological Sciences, The University of Hong Kong, Hong Kong, PR China
    PLoS ONE 8:e64316. 2013
    ..Taken together, TGF-β1 is a potent cytokine that provides an effective mechanism in controlling Necl-2 expression in the testis via Smad-dependent gene repression and clathrin-mediated endocytosis...
  2. ncbi request reprint Transcriptional regulation of cell adhesion at the blood-testis barrier and spermatogenesis in the testis
    Wing Yee Lui
    School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong, China
    Adv Exp Med Biol 763:281-94. 2012
    ..This is a much neglected area of research and a concerted effort by investigators is needed to understand transcriptional regulation of cell adhesion function in the testis particularly at the BTB during spermatogenesis...
  3. ncbi request reprint Nectin-2 expression in testicular cells is controlled via the functional cooperation between transcription factors of the Sp1, CREB, and AP-1 families
    Wing Yee Lui
    Department of Zoology, The University of Hong Kong, Pokfulam, Hong Kong
    J Cell Physiol 207:144-57. 2006
    ..The cross-talk between CREB, c-Jun, and Sp1 family protein is believed to be a major transcription machinery to drive nectin-2 expression in Sertoli cells...
  4. ncbi request reprint Regulation of junction dynamics in the testis--transcriptional and post-translational regulations of cell junction proteins
    Wing Yee Lui
    Department of Zoology, The University of Hong Kong, Pokfulam, Hong Kong, China
    Mol Cell Endocrinol 250:25-35. 2006
    ..Understanding the junction dynamics in the seminiferous epithelium may unfold new targets for non-hormonal male contraceptive development...
  5. ncbi request reprint Expression of CLMP, a novel tight junction protein, is mediated via the interaction of GATA with the Kruppel family proteins, KLF4 and Sp1, in mouse TM4 Sertoli cells
    Kit Ling Sze
    School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong
    J Cell Physiol 214:334-44. 2008
    ..Taken together, this differential interaction of the transcription factors, GATA-1, GATA-6, KLF4, Sp1, and Sp3, in CLMP gene expression might provide a precise machinery in regulating Sertoli cell tight junction dynamics...
  6. ncbi request reprint Mechanisms of reorganization of cell-cell junctions in the testis
    Wing Yee Lui
    School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong
    Front Biosci 13:6775-86. 2008
    ..In this review, the transcriptional, post-transcriptional and post-translational regulations involved in testicular cell junction restructuring are included and specific areas required further attention are also highlighted...
  7. pmc Regulation of cell junction dynamics by cytokines in the testis: a molecular and biochemical perspective
    Wing Yee Lui
    School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong
    Cytokine Growth Factor Rev 18:299-311. 2007
    ..Specifically, we use the adult rat or mouse testis as a model to highlight the significance of transcriptional and translational regulation. Specific areas of research that require further attentions are also highlighted...
  8. ncbi request reprint Dual transcriptional control of claudin-11 via an overlapping GATA/NF-Y motif: positive regulation through the interaction of GATA, NF-YA, and CREB and negative regulation through the interaction of Smad, HDAC1, and mSin3A
    Wing Yee Lui
    Department of Zoology, The University of Hong Kong, Pokfulam, Hong Kong
    J Cell Physiol 211:638-48. 2007
    ....
  9. doi request reprint Opposite effects of interleukin-1alpha and transforming growth factor-beta2 induce stage-specific regulation of junctional adhesion molecule-B gene in Sertoli cells
    Yang Wang
    Division of Endocrinology, School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong
    Endocrinology 150:2404-12. 2009
    ..This study shows for the first time that IL-1alpha and TGF-beta2 regulate JAM-B expression in an opposite manner, and in vitro data obtained herein provide some clues on how junctions are regulated in the testis...
  10. doi request reprint Transforming growth factor-β1 attenuates junctional adhesion molecule-A and contributes to breast cancer cell invasion
    Yang Wang
    School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong
    Eur J Cancer 48:3475-87. 2012
    ..Identification of JAM-A as a downstream target of TGF-β1 represents a crucial mechanism in cancer progression...
  11. ncbi request reprint Post-transcriptional regulation of CLMP mRNA is controlled by tristetraprolin in response to TNFalpha via c-Jun N-terminal kinase signalling
    Kit Ling Sze
    School of Biological Sciences, The University of Hong Kong, Pokfulam, Hong Kong
    Biochem J 410:575-83. 2008
    ..Taken together, these results suggest that the TNFalpha-mediated mRNA degradation of the CLMP gene is controlled by TTP through the JNK signalling cascade...
  12. doi request reprint Molecular mechanisms by which hormones and cytokines regulate cell junction dynamics in the testis
    Wing Yee Lui
    School of Biological Sciences, University of Hong Kong, Hong Kong, People s Republic of China
    J Mol Endocrinol 43:43-51. 2009
    ....
  13. doi request reprint Synergistic effect of interferon-gamma and tumor necrosis factor-alpha on coxsackievirus and adenovirus receptor expression: an explanation of cell sloughing during testicular inflammation in mice
    Ying Gao
    School of Biological Sciences, The University of Hong Kong, Hong Kong, People s Republic of China
    Biol Reprod 90:59. 2014
    ..Taken together, IFNG+TNF treatment significantly downregulates CAR expression, which provides an explanation of how cell sloughing in the epithelium mediates, by loss of CAR-based cell adhesion, during testicular inflammation. ..
  14. ncbi request reprint cAMP perturbs inter-Sertoli tight junction permeability barrier in vitro via its effect on proteasome-sensitive ubiquitination of occludin
    Wing Yee Lui
    Department of Zoology, The University of Hong Kong, Pokfulam, Hong Kong
    J Cell Physiol 203:564-72. 2005
    ....