Geng Li

Summary

Affiliation: The University of Hong Kong
Country: China

Publications

  1. doi request reprint Coenzyme Q10 attenuates beta-amyloid pathology in the aged transgenic mice with Alzheimer presenilin 1 mutation
    Xifei Yang
    The Jockey Club MRI Center, The University of Hong Kong, Hong Kong, China
    J Mol Neurosci 34:165-71. 2008
  2. ncbi request reprint Coenzyme Q10 protects SHSY5Y neuronal cells from beta amyloid toxicity and oxygen-glucose deprivation by inhibiting the opening of the mitochondrial permeability transition pore
    Geng Li
    The Jockey Club MRI Centre, The University of Hong Kong, China
    Biofactors 25:97-107. 2005
  3. ncbi request reprint Neuroprotective effect of Coenzyme Q10 on ischemic hemisphere in aged mice with mutations in the amyloid precursor protein
    Geng Li
    Jockey Club MRI Center, Faculty of Medicine, The University of Hong Kong, Hong Kong, China
    Neurobiol Aging 28:877-82. 2007
  4. ncbi request reprint Cognitive processing in Chinese literate and illiterate subjects: an fMRI study
    Geng Li
    The Jockey Club MRI Center, Faculty of Medicine, The University of Hong Kong, Hong Kong
    Hum Brain Mapp 27:144-52. 2006
  5. ncbi request reprint An fMRI study of somatosensory-implicated acupuncture points in stable somatosensory stroke patients
    Geng Li
    The Jockey Club MRI Centre, Faculty of Medicine, The University of Hong Kong, Hong Kong
    J Magn Reson Imaging 24:1018-24. 2006
  6. doi request reprint Coenzyme Q10 reduces beta-amyloid plaque in an APP/PS1 transgenic mouse model of Alzheimer's disease
    Xifei Yang
    Hong Kong Applied Science and Technology Research Institute Company Limited, Hong Kong, China
    J Mol Neurosci 41:110-3. 2010
  7. ncbi request reprint Spinal effects of acupuncture stimulation assessed by proton density-weighted functional magnetic resonance imaging at 0.2 T
    Geng Li
    The Jockey Club MRI Center, The University of Hong Kong, Pokfulam, Hong Kong
    Magn Reson Imaging 23:995-9. 2005
  8. ncbi request reprint Visual cortical activations on fMRI upon stimulation of the vision-implicated acupoints
    Geng Li
    The Jockey Club MRI Engineering Centre, Department of Electrical and Electronic Engineering, The University of Hong Kong, Pokfulam, Hong Kong
    Neuroreport 14:669-73. 2003
  9. ncbi request reprint Diet supplement CoQ10 delays brain atrophy in aged transgenic mice with mutations in the amyloid precursor protein: an in vivo volume MRI study
    Geng Li
    Hong Kong Applied Science and Technology Research Institute Company Limited, Hong Kong, HKSAR, China
    Biofactors 32:169-78. 2008
  10. doi request reprint An fMRI study of acupuncture-induced brain activation of aphasia stroke patients
    Geng Li
    Hong Kong Time Medical System and Rejuvenis International Ltd, Hong Kong Science Park, Shatin, Hong Kong, China
    Complement Ther Med 19:S49-59. 2011

Collaborators

Detail Information

Publications21

  1. doi request reprint Coenzyme Q10 attenuates beta-amyloid pathology in the aged transgenic mice with Alzheimer presenilin 1 mutation
    Xifei Yang
    The Jockey Club MRI Center, The University of Hong Kong, Hong Kong, China
    J Mol Neurosci 34:165-71. 2008
    ....
  2. ncbi request reprint Coenzyme Q10 protects SHSY5Y neuronal cells from beta amyloid toxicity and oxygen-glucose deprivation by inhibiting the opening of the mitochondrial permeability transition pore
    Geng Li
    The Jockey Club MRI Centre, The University of Hong Kong, China
    Biofactors 25:97-107. 2005
    ..05) when CoQ10 was administered. Our results demonstrate that CoQ10 protects neuronal cells against Abeta neurotoxicity together with OGD by inhibiting the opening of the pore and reducing the concentration of superoxide anion...
  3. ncbi request reprint Neuroprotective effect of Coenzyme Q10 on ischemic hemisphere in aged mice with mutations in the amyloid precursor protein
    Geng Li
    Jockey Club MRI Center, Faculty of Medicine, The University of Hong Kong, Hong Kong, China
    Neurobiol Aging 28:877-82. 2007
    ..We conclude that CoQ10 has a protective effect on the brain from infarction and atrophy induced by ischemic injury in aged and susceptible transgenic mice...
  4. ncbi request reprint Cognitive processing in Chinese literate and illiterate subjects: an fMRI study
    Geng Li
    The Jockey Club MRI Center, Faculty of Medicine, The University of Hong Kong, Hong Kong
    Hum Brain Mapp 27:144-52. 2006
    ..These results indicate that the patterns of neural activation associated with language tasks are strongly influenced by education. Education appears to have enhanced cognitive processing efficiency in language tasks...
  5. ncbi request reprint An fMRI study of somatosensory-implicated acupuncture points in stable somatosensory stroke patients
    Geng Li
    The Jockey Club MRI Centre, Faculty of Medicine, The University of Hong Kong, Hong Kong
    J Magn Reson Imaging 24:1018-24. 2006
    ..To assess differences in brain responses between stroke patients and controls to tactile and electrical acupuncture stimulation using functional MRI (fMRI)...
  6. doi request reprint Coenzyme Q10 reduces beta-amyloid plaque in an APP/PS1 transgenic mouse model of Alzheimer's disease
    Xifei Yang
    Hong Kong Applied Science and Technology Research Institute Company Limited, Hong Kong, China
    J Mol Neurosci 41:110-3. 2010
    ..These data demonstrate that in addition to reducing intracellular deposition of Abeta, CoQ10 can also reduce plaque pathology. Our study further supports the use of CoQ10 as a therapeutic candidate for AD...
  7. ncbi request reprint Spinal effects of acupuncture stimulation assessed by proton density-weighted functional magnetic resonance imaging at 0.2 T
    Geng Li
    The Jockey Club MRI Center, The University of Hong Kong, Pokfulam, Hong Kong
    Magn Reson Imaging 23:995-9. 2005
    ..During stimulation, 8 of the 11 subjects had consistent functional activations in C6/C7. A bilateral activation pattern was common. Our findings show that acupoint stimulation modulates activity in the spinal cord...
  8. ncbi request reprint Visual cortical activations on fMRI upon stimulation of the vision-implicated acupoints
    Geng Li
    The Jockey Club MRI Engineering Centre, Department of Electrical and Electronic Engineering, The University of Hong Kong, Pokfulam, Hong Kong
    Neuroreport 14:669-73. 2003
    ..Thus, acupuncture may modulate the activity of relevant brain sites. Our results also suggest that electro-acupuncture is useful in future studies...
  9. ncbi request reprint Diet supplement CoQ10 delays brain atrophy in aged transgenic mice with mutations in the amyloid precursor protein: an in vivo volume MRI study
    Geng Li
    Hong Kong Applied Science and Technology Research Institute Company Limited, Hong Kong, HKSAR, China
    Biofactors 32:169-78. 2008
    ..Our result indicated that CoQ10 may have therapeutic potential in the prevention and treatment of MCI and AD...
  10. doi request reprint An fMRI study of acupuncture-induced brain activation of aphasia stroke patients
    Geng Li
    Hong Kong Time Medical System and Rejuvenis International Ltd, Hong Kong Science Park, Shatin, Hong Kong, China
    Complement Ther Med 19:S49-59. 2011
    ..These results suggest that acupuncture may have therapeutic benefits in post-stroke aphasia patients...
  11. ncbi request reprint Cortical activations upon stimulation of the sensorimotor-implicated acupoints
    Geng Li
    The Jockey Club MRI Engineering Centre, Faculty of Engineering, The University of Hong Kong, Hong Kong
    Magn Reson Imaging 22:639-44. 2004
    ..Our results indicate the existence of sensorimotor-implicated acupoints as sensitive sites to obtain somatotopic activations over the sensory cortices with co-activation of the motor cortices...
  12. ncbi request reprint Melatonin reduces infarction volume in a photothrombotic stroke model in the wild-type but not cyclooxygenase-1-gene knockout mice
    Liang Yu Zou
    Division of Neurology, University Department of Medicine, The University of Hong Kong, Hong Kong
    J Pineal Res 41:150-6. 2006
    ..Melatonin treatment reduces infarct size in the wild-type mice following photothrombotic stroke partly via maintenance of penumbral CBF in which the COX-1-gene may play a role...
  13. ncbi request reprint An fMRI study comparing brain activation between word generation and electrical stimulation of language-implicated acupoints
    Geng Li
    The Jockey Club Magnetic Resonance Imaging Engineering Centre, The University of Hong Kong, Hong Kong
    Hum Brain Mapp 18:233-8. 2003
    ..Although our results support the notion of acupoint-brain activation, applying acupuncture at SJ 8 or Du 15 does not activate the typical language areas in the left inferior frontal cortex...
  14. pmc Physiology and cell biology of acupuncture observed in calcium signaling activated by acoustic shear wave
    Geng Li
    Time Medical Systems, No 2, Science Park West Avenue, Hong Kong, China
    Pflugers Arch 462:587-97. 2011
    ..ASW signaling makes use of the anisotropy of elasticity of tissues as its waveguides for transmission and that cell activation is not based on the nervous system...
  15. ncbi request reprint Proton-density-weighted spinal fMRI with sensorimotor stimulation at 0.2 T
    Man Cheuk Ng
    Department of Orthopaedics and Traumatology, The University of Hong Kong, Pokfulam, 5 F, Professor Block, Queen Mary Hospital, Pokfulam, Hong Kong
    Neuroimage 29:995-9. 2006
    ..Our results suggested the existence of task-driven proton density change in the cervical spinal cord...
  16. doi request reprint Neural correlates of nouns and verbs in early bilinguals
    Alice H D Chan
    State Key Laboratory of Brain and Cognitive Sciences, University of Hong Kong, Hong Kong, China
    Ann N Y Acad Sci 1145:30-40. 2008
    ..Our findings are consistent with the theory that neural circuits for linguistic dimensions are weighted and modulated by the characteristics of a language...
  17. ncbi request reprint Identification of a novel prostate cancer-associated tumor antigen
    Amanda K Miles
    School of Biomedical and Natural Science, Nottingham Trent University, Clifton Lane, Clifton, Nottingham, United Kingdom
    Prostate 67:274-87. 2007
    ..Using sera from cancer patients, we have previously reported on the identification of immunologically recognized proteins that belong to the family of cancer testis antigens (CTAs)...
  18. ncbi request reprint Derivative temporal clustering analysis: detecting prolonged neuronal activity
    Xia Zhao
    Research Imaging Center, University of Texas Health Science Center at San Antonio, San Antonio, TX, USA
    Magn Reson Imaging 25:183-7. 2007
    ..By removing the limitations in the previous TCA, DTCA has shown its powerful capability in detecting prolonged plateau neuronal activities...
  19. ncbi request reprint Peptide immunisation of HLA-DR-transgenic mice permits the identification of a novel HLA-DRbeta1*0101- and HLA-DRbeta1*0401-restricted epitope from p53
    José Manuel Rojas
    School of Sciences, The Nottingham Trent University, Clifton Lane, Nottingham, NG11 8NS, UK
    Cancer Immunol Immunother 54:243-53. 2005
    ....
  20. ncbi request reprint Anti-tumour therapeutic efficacy of OX40L in murine tumour model
    Selman A Ali
    School of Science, Nottingham Trent University, Clifton Lane, Nottingham NG11 8NS, UK
    Vaccine 22:3585-94. 2004
    ..These results demonstrate the potential role of the OX40L in cancer immunotherapy...
  21. ncbi request reprint A prototype methodology combining surface-enhanced laser desorption/ionization protein chip technology and artificial neural network algorithms to predict the chemoresponsiveness of breast cancer cell lines exposed to Paclitaxel and Doxorubicin under in v
    Shahid Mian
    Interdisciplinary Biomedical Research Building, Faculty of Science and Land based Studies, Nottingham Trent University, Nottingham, UK
    Proteomics 3:1725-37. 2003
    ....