N Lee

Summary

Affiliation: The Chinese University of Hong Kong
Country: China

Publications

  1. pmc Effect of sequence variation in Plasmodium falciparum histidine- rich protein 2 on binding of specific monoclonal antibodies: Implications for rapid diagnostic tests for malaria
    Nelson Lee
    Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research and School of Population Health, University of Queensland, Queensland, Australia
    J Clin Microbiol 44:2773-8. 2006
  2. doi Fecal detection of influenza A virus in patients with concurrent respiratory and gastrointestinal symptoms
    Martin C W Chan
    Institute of Digestive Disease, Chinese University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of China
    J Clin Virol 45:208-11. 2009
  3. doi Clinical management of pandemic 2009 influenza A(H1N1) infection
    David S Hui
    Division of Respiratory Medicine, The Chinese University of Hong Kong, 9 F, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, New Territories, Hong Kong
    Chest 137:916-25. 2010
  4. doi Outcomes of adults hospitalised with severe influenza
    N Lee
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong
    Thorax 65:510-5. 2010
  5. pmc Cytokine response patterns in severe pandemic 2009 H1N1 and seasonal influenza among hospitalized adults
    Nelson Lee
    Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region, People s Republic of China
    PLoS ONE 6:e26050. 2011
  6. doi Role of human Toll-like receptors in naturally occurring influenza A infections
    Nelson Lee
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
    Influenza Other Respir Viruses 7:666-75. 2013
  7. ncbi Influenza virus load in hospitalised patients
    N Lee
    Division of Infectious Diseases, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    Hong Kong Med J 19:15-8. 2013
  8. doi Diagnosis, management and outcomes of adults hospitalized with influenza
    Nelson Lee
    Division of Infectious Diseases, Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    Antivir Ther 17:143-57. 2012
  9. pmc Acute encephalopathy associated with influenza A infection in adults
    Nelson Lee
    Division of Infectious Diseases, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, 9 F Clinical Sciences Building, Department of Medicine and Therapeutics, Shatin, Hong Kong, People s Republic of China
    Emerg Infect Dis 16:139-42. 2010
  10. ncbi Risk factors associated with life-threatening rickettsial infections
    Nelson Lee
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, People s Republic of China
    Am J Trop Med Hyg 78:973-8. 2008

Detail Information

Publications68

  1. pmc Effect of sequence variation in Plasmodium falciparum histidine- rich protein 2 on binding of specific monoclonal antibodies: Implications for rapid diagnostic tests for malaria
    Nelson Lee
    Australian Centre for International and Tropical Health and Nutrition, Queensland Institute of Medical Research and School of Population Health, University of Queensland, Queensland, Australia
    J Clin Microbiol 44:2773-8. 2006
    ..These findings support the role of sequence variation as an explanation for variations in the performance of HRP2-based RDTs and point toward possible approaches to improve their diagnostic sensitivities...
  2. doi Fecal detection of influenza A virus in patients with concurrent respiratory and gastrointestinal symptoms
    Martin C W Chan
    Institute of Digestive Disease, Chinese University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of China
    J Clin Virol 45:208-11. 2009
    ..In seasonal influenza, gastrointestinal symptoms such as diarrhea, vomiting, and abdominal pain are sometimes observed, especially among young children. However, fecal excretion of seasonal influenza virus has seldom been studied...
  3. doi Clinical management of pandemic 2009 influenza A(H1N1) infection
    David S Hui
    Division of Respiratory Medicine, The Chinese University of Hong Kong, 9 F, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, New Territories, Hong Kong
    Chest 137:916-25. 2010
    ..Nonpharmacologic measures, such as early case isolation, household quarantine, school/workplace closure, good community hygiene, and restrictions on travel are useful measures in controlling an influenza pandemic at its early phase...
  4. doi Outcomes of adults hospitalised with severe influenza
    N Lee
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong
    Thorax 65:510-5. 2010
    ..The aim of this study was to investigate factors affecting clinical outcomes of adults hospitalised with severe seasonal influenza...
  5. pmc Cytokine response patterns in severe pandemic 2009 H1N1 and seasonal influenza among hospitalized adults
    Nelson Lee
    Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong, Special Administrative Region, People s Republic of China
    PLoS ONE 6:e26050. 2011
    ..Studying cytokine/chemokine responses in severe influenza infections caused by different virus subtypes may improve understanding on pathogenesis...
  6. doi Role of human Toll-like receptors in naturally occurring influenza A infections
    Nelson Lee
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
    Influenza Other Respir Viruses 7:666-75. 2013
    ..We investigated the roles of Toll-like receptors (TLRs) in naturally occurring influenza...
  7. ncbi Influenza virus load in hospitalised patients
    N Lee
    Division of Infectious Diseases, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    Hong Kong Med J 19:15-8. 2013
    ..5. Randomised, controlled trials are indicated to address timing and dosage of treatment for severe influenza infection...
  8. doi Diagnosis, management and outcomes of adults hospitalized with influenza
    Nelson Lee
    Division of Infectious Diseases, Department of Medicine and Therapeutics, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong SAR, China
    Antivir Ther 17:143-57. 2012
    ....
  9. pmc Acute encephalopathy associated with influenza A infection in adults
    Nelson Lee
    Division of Infectious Diseases, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, 9 F Clinical Sciences Building, Department of Medicine and Therapeutics, Shatin, Hong Kong, People s Republic of China
    Emerg Infect Dis 16:139-42. 2010
    ..Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis...
  10. ncbi Risk factors associated with life-threatening rickettsial infections
    Nelson Lee
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, People s Republic of China
    Am J Trop Med Hyg 78:973-8. 2008
    ..014). Treatment with fluoroquinolone/clarithromycin did not correlate with clinical outcomes (P > 0.05). Early empirical doxycycline therapy should be considered if clinico-epidemiologic signs of rickettsial infections are present...
  11. ncbi Factors associated with early hospital discharge of adult influenza patients
    Nelson Lee
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Antivir Ther 12:501-8. 2007
    ..Understanding factors affecting length of hospital stay (LOS) in patients with severe influenza may improve their management...
  12. ncbi Hypercytokinemia and hyperactivation of phospho-p38 mitogen-activated protein kinase in severe human influenza A virus infection
    N Lee
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of China
    Clin Infect Dis 45:723-31. 2007
    ..We postulate that hypercytokinemia plays a role in immunopathogenesis of severe human influenza...
  13. ncbi Co-circulation of human metapneumovirus and SARS-associated coronavirus during a major nosocomial SARS outbreak in Hong Kong
    N Lee
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
    J Clin Virol 40:333-7. 2007
    ..The clinico-epidemiological significance of human metapneumovirus (hMPV) detected during the SARS outbreak is unknown...
  14. doi Interferon gamma release assay for differentiating tuberculosis among pneumonia cases in acute healthcare setting
    G Lui
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    J Infect 62:440-7. 2011
    ..Early diagnosis of smear-negative tuberculosis remains challenging. The role of an interferon-gamma release assay (IGRA) in discriminating active pulmonary tuberculosis (PTB) among cases of 'pneumonia' was investigated...
  15. ncbi Features discriminating SARS from other severe viral respiratory tract infections
    T H Rainer
    Accident and Emergency Medicine Academic Unit, The Chinese University of Hong Kong, Rooms 107 113, 1st Floor, Shatin, NT, Hong Kong
    Eur J Clin Microbiol Infect Dis 26:121-9. 2007
    ..9-96.9). Certain clinical manifestations and laboratory changes may help to distinguish SARS from other influenza-like illnesses. Scoring systems may help identify patients who should receive more specific tests for influenza or SARS...
  16. ncbi Role of laboratory variables in differentiating SARS-coronavirus from other causes of community-acquired pneumonia within the first 72 h of hospitalization
    N Lee
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Eur J Clin Microbiol Infect Dis 25:765-72. 2006
    ....
  17. ncbi Thin-section CT in patients with severe acute respiratory syndrome following hospital discharge: preliminary experience
    Gregory E Antonio
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Chinese University of Hong Kong, 30 32 Ngan Shing St, Shatin, Hong Kong SAR
    Radiology 228:810-5. 2003
    ..To report the initial experience regarding thin-section computed tomographic (CT) findings in patients with severe acute respiratory syndrome (SARS) who improved clinically after treatment...
  18. doi Differences in the compliance with hospital infection control practices during the 2009 influenza H1N1 pandemic in three countries
    J S Y Chor
    School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong
    J Hosp Infect 81:98-103. 2012
    ..In December 2009, the World Health Organization (WHO) issued updated guidelines on the prevention of H1N1 influenza virus in healthcare settings. In 2010, the WHO pandemic influenza alert level was still at phase 6...
  19. doi Disease severity prediction for nursing home-acquired pneumonia in the emergency department
    S Y Man
    Accident and Emergency Medicine Academic Unit, Chinese University of Hong Kong, Trauma and Emergency Centre, Prince of Wales Hospital, Shatin, NT, Hong Kong SAR
    Emerg Med J 28:1046-50. 2011
    ....
  20. ncbi Cryptococcosis in apparently immunocompetent patients
    G Lui
    Division of Infectious Diseases, Department of Medicine and Therapeutics, 9 F Clinical Sciences Building, Prince of Wales Hospital, Hong Kong
    QJM 99:143-51. 2006
    ..Few reports have described the clinical and microbiological features of cryptococcosis in immunocompetent patients...
  21. ncbi Temporal-spatial analysis of severe acute respiratory syndrome among hospital inpatients
    Ignatius T S Yu
    Department of Community and Family Medicine, Chinese University of Hong Kong, Hong Kong, China
    Clin Infect Dis 40:1237-43. 2005
    ..We report the temporal-spatial spread of severe acute respiratory syndrome (SARS) among inpatients in a hospital ward during a major nosocomial outbreak and discuss possible mechanisms for the outbreak...
  22. ncbi Why did outbreaks of severe acute respiratory syndrome occur in some hospital wards but not in others?
    Ignatius T Yu
    Centre for Emerging Infectious Disease, The Chinese University of Hong Kong, Shatin, Hong Kong Special Administrative Region, China
    Clin Infect Dis 44:1017-25. 2007
    ..We systematically analyzed the risk factors for nosocomial outbreaks of SARS among hospital wards in Guangzhou and Hong Kong, China...
  23. ncbi Value of serum procalcitonin, neopterin, and C-reactive protein in differentiating bacterial from viral etiologies in patients presenting with lower respiratory tract infections
    Margaret Ip
    Department of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Diagn Microbiol Infect Dis 59:131-6. 2007
    ..857, whereas (CRP x PCT)/neopterin was 0.856. Combination of 2 or all 3 of the biomarkers may improve the discriminatory power in delineating bacterial versus viral etiology in LRTI...
  24. ncbi A comparison of three transarterial lipiodol-based formulations for hepatocellular carcinoma: in vivo biodistribution study in humans
    Simon Chun Ho Yu
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Chinese University of Hong Kong, 30 32 Ngan Shing Street, Shatin, New Territories, Hong Kong
    Cardiovasc Intervent Radiol 31:289-98. 2008
    ..013). This study showed that LEM is associated with a greater embolic effect in intrahepatic HCC at 4 weeks, and a comparable degree of lung shunting and decomposition rates, compared with ethanol-free Lipiodol formulations...
  25. doi Failure to confirm HIV infection in two end-stage HIV/AIDS patients using a popular commercial line immunoassay
    Julian W Tang
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR
    J Med Virol 80:1515-22. 2008
    ..This report highlights the utility of having NAT available when diagnosing difficult cases of HIV infection, especially in light of the recent Centers for Disease Control and Prevention move towards more universal, routine, HIV testing...
  26. doi Diagnostic utility of CRP to neopterin ratio in patients with acute respiratory tract infections
    Timothy H Rainer
    Accident and Emergency Academic Unit, Chinese University of Hong Kong, Prince of Wales Hospital, New Territories, Hong Kong
    J Infect 58:123-30. 2009
    ....
  27. pmc Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control study
    K C Allen Chan
    The Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong
    BMC Infect Dis 5:26. 2005
    ..Thus, we have investigated the association between ACE insertion/deletion (I/D) polymorphism and the progression to ARDS or requirement of intensive care in SARS patients...
  28. ncbi Seroprevalence of antibody to severe acute respiratory syndrome (SARS)-associated coronavirus among health care workers in SARS and non-SARS medical wards
    Margaret Ip
    Department of Microbiology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong, People s Republic of China
    Clin Infect Dis 38:e116-8. 2004
    ..Rates for clinical SARS-CoV infection among 742 HCWs on these wards were highest among nurses (11.6%) and health care assistants (11.8%), indicating that these occupations are associated with the highest risks for exposure...
  29. ncbi Enteric involvement of severe acute respiratory syndrome-associated coronavirus infection
    Wai K Leung
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Gastroenterology 125:1011-7. 2003
    ..Herein, we describe the clinical, pathologic, and virologic features of the intestinal involvement of this new viral infection...
  30. pmc Immunofluorescence assay for serologic diagnosis of SARS
    Paul K S Chan
    Department of Microbiology, Faculty of Medicine, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, People s Republic of China
    Emerg Infect Dis 10:530-2. 2004
    ..Sensitivity and specificity of this assay were both 100%. Immunofluorescence assay can ascertain the status of SARS-CoV infection...
  31. pmc Laboratory diagnosis of SARS
    Paul K S Chan
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China
    Emerg Infect Dis 10:825-31. 2004
    ..Positive virologic test results in patient groups were associated with mechanical ventilation or death (p < 0.001), suggesting a correlation between viral load and disease severity...
  32. pmc Human metapneumovirus detection in patients with severe acute respiratory syndrome
    Paul K S Chan
    Faculty of Medicine of the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Emerg Infect Dis 9:1058-63. 2003
    ..These widely available HEp-2 cells should be included in conjunction with a molecular method for cell culture followup to detect HMPV, particularly in patients with SARS...
  33. ncbi The spectrum of severe acute respiratory syndrome-associated coronavirus infection
    Timothy H Rainer
    Accident and Emergency Medicine Academic Unit, The Chinese University of Hong Kong, Trauma and Emergency Centre, Prince of Wales Hospital, Shatin, NT, Hong Kong
    Ann Intern Med 140:614-9. 2004
    ..Objectives: To describe the spectrum of SARS coronavirus infection in a large outbreak and to compare diagnoses based on clinical judgment with the SARS coronavirus test...
  34. pmc Severe acute respiratory syndrome-associated coronavirus infection
    Paul K S Chan
    The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Emerg Infect Dis 9:1453-4. 2003
    ..None of these healthcare workers had antibody to SARS CoV, indicating that subclinical or mild infection attributable to SARS-CoV in adults is rare...
  35. ncbi Imaging of severe acute respiratory syndrome in Hong Kong
    Gregory E Antonio
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Chinese University of Hong Kong, 30 32 Ngan Shing St, Shatin, Hong Kong, Republic of China
    AJR Am J Roentgenol 181:11-7. 2003
  36. pmc Fecal viral concentration and diarrhea in norovirus gastroenteritis
    Nelson Lee
    Prince of Wales Hospital, Hong Kong Special Administrative Region, People s Republic of China
    Emerg Infect Dis 13:1399-401. 2007
    ..Higher viral concentration and older age were independently associated with prolonged diarrhea (> or =4 days). These findings provide information on the pathogenesis and transmission of norovirus infections...
  37. ncbi Quantitative analysis and prognostic implication of SARS coronavirus RNA in the plasma and serum of patients with severe acute respiratory syndrome
    Enders K O Ng
    Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong Special Administrative Region, China
    Clin Chem 49:1976-80. 2003
    ..We investigated whether the SARS coronavirus (SARS-CoV) can be detected in serum and plasma samples during the early stages of SARS and studied the potential prognostic implications of such an approach...
  38. doi Allele-specific conventional reverse-transcription polymerase chain reaction as a screening assay for discriminating influenza a H1N1 (H275Y) oseltamivir-resistant and wild-type viruses
    Karry L K Ngai
    Faculty of Medicine, Department of Microbiology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong Special Administration Region, China
    J Med Virol 82:1295-8. 2010
    ..Further improvement in performance is expected when applied to cell culture isolates with a higher viral titer. These allele-specific cRT-PCR assays can be a simple, low-cost option for large-scale screening of influenza isolates...
  39. ncbi Effects of early corticosteroid treatment on plasma SARS-associated Coronavirus RNA concentrations in adult patients
    Nelson Lee
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, China
    J Clin Virol 31:304-9. 2004
    ..The effect of corticosteroid treatment on the viral load of Severe Acute Respiratory Syndrome (SARS) patients is unknown...
  40. ncbi Severe acute respiratory syndrome: thin-section computed tomography features, temporal changes, and clinicoradiologic correlation during the convalescent period
    Ka Tak Wong
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Hong Kong, China
    J Comput Assist Tomogr 28:790-5. 2004
    ..To evaluate thin-section computed tomography findings of patients with severe acute respiratory syndrome (SARS) in the convalescent period and to correlate the results with clinical parameters and lung function tests...
  41. pmc Severe acute respiratory syndrome: report of treatment and outcome after a major outbreak
    J J Y Sung
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong
    Thorax 59:414-20. 2004
    ..The outcome is reported of a prospective uncontrolled study based on a stepwise treatment protocol during an outbreak of severe acute respiratory syndrome (SARS) in Hong Kong...
  42. doi Frequent detection of plasmid-mediated quinolone resistance (qnr) genes in multidrug-resistant Enterobacteriaceae blood isolates, Hong Kong
    C C Lee
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 9 F, Clinical Sciences Building, Shatin, Hong Kong SAR, China
    Eur J Clin Microbiol Infect Dis 31:3183-9. 2012
    ..Further dissemination of qnr and selection of fluoroquinolone/β-lactam-resistant strains should be closely monitored and controlled...
  43. doi Preventing healthcare workers from acquiring influenza
    Tak Ching Ng
    Department of Medicine and Therapeutics, Prince of Wales Hospital, and the Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Shatin, Hong Kong
    Infect Control Hosp Epidemiol 30:292-5. 2009
    ..56) during high-risk procedures, and failure to receive influenza vaccination (odds ratio, 4.82) were independent risk factors, adjusted for household contacts...
  44. ncbi Anti-SARS-CoV IgG response in relation to disease severity of severe acute respiratory syndrome
    Nelson Lee
    Department of Medicine and Therapeutics, Prince of Wales Hospital, Faculty of Medicine, The Chinese University of Hong Kong, 30 32 Ngan Shing Street, Shatin, NT, Hong Kong, PR China
    J Clin Virol 35:179-84. 2006
    ..The association between a robust or depressed antibody response and clinical severity of SARS remains unknown...
  45. doi Viral loads and duration of viral shedding in adult patients hospitalized with influenza
    Nelson Lee
    Department of Medicine and Therapeutics, Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    J Infect Dis 200:492-500. 2009
    ..The goal of this study was to characterize viral loads and factors affecting viral clearance in persons with severe influenza...
  46. doi Cytokine responses in a severe case of glandular fever treated successfully with foscarnet combined with prednisolone and intravenous immunoglobulin
    Christine Ma
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    J Med Virol 81:99-105. 2009
    ..Detailed immunological, virological, haematological and biochemical laboratory parameters are presented to document this patient's severe EBV disease and eventual recovery...
  47. pmc Cardiovascular complications of severe acute respiratory syndrome
    C M Yu
    Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    Postgrad Med J 82:140-4. 2006
    ..Severe acute respiratory syndrome (SARS) is a virulent viral infection that affects a number of organs and systems. This study examined if SARS may result in cardiovascular complications...
  48. ncbi Fever, pulmonary haemorrhage, and acute renal failure in a young girl
    F W T Cheng
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Hong Kong Med J 11:408-10. 2005
    ..She presented with fever, hypotension, jaundice, and acute renal failure. She had used well water for bathing and swum in freshwater...
  49. doi Role of 'atypical pathogens' among adult hospitalized patients with community-acquired pneumonia
    Grace Lui
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong
    Respirology 14:1098-105. 2009
    ..This study examined the role of these 'atypical pathogens' (AP) among adult hospitalized patients with CAP...
  50. pmc Willingness of Hong Kong healthcare workers to accept pre-pandemic influenza vaccination at different WHO alert levels: two questionnaire surveys
    Josette S Y Chor
    School of Public Health and Primary Care, Chinese University of Hong Kong, School of Public Health, Prince of Wales Hospital, Shatin, Hong Kong
    BMJ 339:b3391. 2009
    ..To assess the acceptability of pre-pandemic influenza vaccination among healthcare workers in public hospitals in Hong Kong and the effect of escalation in the World Health Organization's alert level for an influenza pandemic...
  51. doi Development and comparison of molecular assays for the rapid detection of the pandemic influenza A (H1N1) 2009 virus
    Wai Yip Lam
    Faculty of Medicine, Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, People s Republic of China
    J Med Virol 82:675-83. 2010
    ..The newly developed cRT-PCR assay targeting the HA gene allows rapid, specific, and sensitive screening of this novel agent, which can serve as an alternative for laboratories where a real-time PCR machine is not available...
  52. ncbi Thin-section CT of severe acute respiratory syndrome: evaluation of 73 patients exposed to or with the disease
    K T Wong
    Department of Diagnostic Radiology, Prince of Wales Hospital, Chinese University of Hong Kong, 30 32 Ngan Shing St, Shatin, Hong Kong SAR
    Radiology 228:395-400. 2003
    ..To retrospectively analyze the thin-section computed tomographic (CT) features in patients with severe acute respiratory syndrome (SARS) at the authors' institution...
  53. pmc Pulmonary pathological features in coronavirus associated severe acute respiratory syndrome (SARS)
    G M K Tse
    Department of Anatomical and Cellular Pathology, Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing Street, Shatin, NT, Hong Kong SAR, China
    J Clin Pathol 57:260-5. 2004
    ..2%. This new human emergent infectious disease is dominated by severe lower respiratory illness and is aetiologically linked to a new coronavirus (SARS-CoV)...
  54. pmc Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis
    Raymond S M Wong
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China
    BMJ 326:1358-62. 2003
    ..To evaluate the haematological findings of patients with severe acute respiratory syndrome (SARS)...
  55. pmc Prospective comparison of three predictive rules for assessing severity of community-acquired pneumonia in Hong Kong
    Shin Yan Man
    Accident and Emergency Medicine Academic Unit, Chinese University of Hong Kong, Trauma and Emergency Centre, Prince of Wales Hospital, Shatin, NT, Hong Kong
    Thorax 62:348-53. 2007
    ..Community-acquired pneumonia (CAP) is a leading infectious cause of death throughout the world, including Hong Kong...
  56. ncbi Severe acute respiratory syndrome: radiographic appearances and pattern of progression in 138 patients
    K T Wong
    Department of Diagnostic Radiology, Prince of Wales Hospital, Chinese University of Hong Kong, 30 32 Ngan Shing St, Shatin, Hong Kong SAR
    Radiology 228:401-6. 2003
    ..To retrospectively evaluate the radiographic appearances and pattern of progression of severe acute respiratory syndrome (SARS)...
  57. ncbi Rates of disease progression among human immunodeficiency virus-infected persons initiating multiple-drug rescue therapy
    Nelson Lee
    British Columbia Centre for Excellence in HIV AIDS, Vancouver, British Columbia, Canada
    J Infect Dis 188:137-41. 2003
    ..Over the short-term, patients receiving MDRT had relatively low mortality. After adjustment for baseline prognostic factors, rates of survival were comparable with those in patients initiating triple-drug ART...
  58. ncbi Provider bias in the selection of non-nucleoside reverse transcriptase inhibitor and protease inhibitor-based highly active antiretroviral therapy and HIV treatment outcomes in observational studies
    Evan Wood
    BC Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, Canada
    AIDS 17:2629-34. 2003
    ....
  59. pmc Diagnostic criteria during SARS outbreak in Hong Kong
    Louis Y Chan
    Emerg Infect Dis 10:1168-70. 2004
  60. ncbi A major outbreak of severe acute respiratory syndrome in Hong Kong
    Nelson Lee
    Department of Medicine, Chinese University of Hong Kong, Hong Kong, China
    N Engl J Med 348:1986-94. 2003
    ..There has been an outbreak of the severe acute respiratory syndrome (SARS) worldwide. We report the clinical, laboratory, and radiologic features of 138 cases of suspected SARS during a hospital outbreak in Hong Kong...
  61. ncbi Epstein-Barr virus-associated smooth muscle tumor in patients with acquired immunodeficiency syndrome
    Ka Hing Wong
    Integrated Treatment Centre, Special Preventive Programme, Centre for Health Protection, Department of Health, Kowloon, Hong Kong
    J Microbiol Immunol Infect 40:173-7. 2007
    ..This report describes the case of 2 AIDS patients with EBV-associated SMT and highlights the features and outcome of this rare but potentially important tumor in human immunodeficiency virus management...
  62. ncbi Severe acute respiratory syndrome: correlation between clinical outcome and radiologic features
    David S C Hui
    Department of Diagnostic Radiology and Organ Imaging, The Chinese Univ of Hong Kong, Prince of Wales Hosp, 30 32 Ngan Shing St, Shatin, Hong Kong SAR
    Radiology 233:579-85. 2004
    ..To evaluate whether there is a correlation between the clinical outcomes and radiologic features of severe acute respiratory syndrome (SARS)...
  63. pmc Chikungunya fever, Hong Kong
    Nelson Lee
    Emerg Infect Dis 12:1790-2. 2006
  64. ncbi Retrospective analysis of liver function derangement in severe acute respiratory syndrome
    Henry L Y Chan
    Am J Med 116:566-7. 2004
  65. ncbi Penicilliosis: an AIDS-defining disease in Asia
    Nelson Lee
    Hong Kong Med J 14:88-9. 2008
  66. ncbi Clinical significance of hepatic derangement in severe acute respiratory syndrome
    Henry Lik Yuen Chan
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, China
    World J Gastroenterol 11:2148-53. 2005
    ..We report the progression and clinical significance of liver derangement in a large cohort of SARS patient...
  67. ncbi Cytokine profile in fatal human immunodeficiency virus tuberculosis Epstein-Barr virus associated hemophagocytic syndrome
    Chun K Wong
    Arch Intern Med 167:1901-3. 2007
  68. ncbi Clinical role of beta-lactam/beta-lactamase inhibitor combinations
    Nelson Lee
    Division of Clinical Pharmacology, Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Drugs 63:1511-24. 2003
    ..In certain scenarios, they could even be more cost-effective than conventional combination therapies. With the accumulation of so much clinical experience, their role in the management of infections is now becoming more clearly defined...