Wan-yee Lau

Summary

Affiliation: The Chinese University of Hong Kong
Country: China

Publications

  1. ncbi request reprint Primary liver tumors
    W Y Lau
    Department of Surgery, Chinese University of Hong Kong, Shatin, New Territories
    Semin Surg Oncol 19:135-44. 2000
  2. ncbi request reprint Development and controversies of adjuvant therapy for pancreatic cancer
    Wan Yee Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Hepatobiliary Pancreat Dis Int 7:121-5. 2008
  3. ncbi request reprint Hepatocellular carcinoma: current management and recent advances
    Wan Yee Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Hepatobiliary Pancreat Dis Int 7:237-57. 2008
  4. pmc Application of tumor-node-metastasis staging 2002 version in locally advanced hepatocellular carcinoma: is it predictive of surgical outcome?
    Binkui Li
    State Key Laboratory of Oncology in South China, Guangzhou, China
    BMC Cancer 10:535. 2010
  5. ncbi request reprint Differential gene expression of hepatocellular carcinoma using cDNA microarray analysis
    W Y Lau
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, SAR
    Oncol Res 12:59-69. 2000
  6. ncbi request reprint Hepatic resection for colorectal liver metastases
    W Y Lau
    Department of Surgery, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    Singapore Med J 48:635-9. 2007
  7. doi request reprint The current role of radiofrequency ablation in the management of hepatocellular carcinoma: a systematic review
    Wan Yee Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Ann Surg 249:20-5. 2009
  8. ncbi request reprint Induction of Fas and Fas ligand expression on malignant glioma cells by Kupffer cells, a potential pathway of antiliver metastases
    W Y Lau
    Department of Surgery, Prince of Wales Hospital, Shatin, N T, Hong Kong
    J Surg Res 101:44-51. 2001
  9. ncbi request reprint Management of hepatocellular carcinoma
    W Y Lau
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories
    J R Coll Surg Edinb 47:389-99. 2002
  10. ncbi request reprint Current therapy of hilar cholangiocarcinoma
    Stephanie Hiu Yan Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    Hepatobiliary Pancreat Dis Int 11:12-7. 2012

Detail Information

Publications75

  1. ncbi request reprint Primary liver tumors
    W Y Lau
    Department of Surgery, Chinese University of Hong Kong, Shatin, New Territories
    Semin Surg Oncol 19:135-44. 2000
    ....
  2. ncbi request reprint Development and controversies of adjuvant therapy for pancreatic cancer
    Wan Yee Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Hepatobiliary Pancreat Dis Int 7:121-5. 2008
    ..An effective adjuvant therapy is urgently needed to improve the surgical outcome. This review describes the current status of adjuvant therapy for pancreatic cancer, and highlights its controversies...
  3. ncbi request reprint Hepatocellular carcinoma: current management and recent advances
    Wan Yee Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Hepatobiliary Pancreat Dis Int 7:237-57. 2008
    ..This article aims to review the current management of HCC and its recent advances...
  4. pmc Application of tumor-node-metastasis staging 2002 version in locally advanced hepatocellular carcinoma: is it predictive of surgical outcome?
    Binkui Li
    State Key Laboratory of Oncology in South China, Guangzhou, China
    BMC Cancer 10:535. 2010
    ..The aim of our study was to verify whether the 2002 version of the Tumor-Node-Metastasis staging system could predict surgical outcomes in patients with locally advanced HCC...
  5. ncbi request reprint Differential gene expression of hepatocellular carcinoma using cDNA microarray analysis
    W Y Lau
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, SAR
    Oncol Res 12:59-69. 2000
    ..It is concluded that cDNA microarray analysis is an effective method in the detection of differential gene expression in HCC...
  6. ncbi request reprint Hepatic resection for colorectal liver metastases
    W Y Lau
    Department of Surgery, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    Singapore Med J 48:635-9. 2007
    ..However, liver resection can be performed in only ten percent of patients. A strategy to improve resectability and outcome of patients with colorectal liver metastases is needed...
  7. doi request reprint The current role of radiofrequency ablation in the management of hepatocellular carcinoma: a systematic review
    Wan Yee Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Ann Surg 249:20-5. 2009
    ..To review the current status of radiofrequency ablation (RFA) in the management of hepatocellular carcinoma (HCC)...
  8. ncbi request reprint Induction of Fas and Fas ligand expression on malignant glioma cells by Kupffer cells, a potential pathway of antiliver metastases
    W Y Lau
    Department of Surgery, Prince of Wales Hospital, Shatin, N T, Hong Kong
    J Surg Res 101:44-51. 2001
    ..Therefore, this study supports a novel pathway of Kupffer cells against liver metastases, in which tumor cells were apoptotic via the Fas-Fas ligand system induced by TNFalpha released from Kupffer cells...
  9. ncbi request reprint Management of hepatocellular carcinoma
    W Y Lau
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories
    J R Coll Surg Edinb 47:389-99. 2002
    ..The results of systemic immunotherapy or systemic tamoxifen on HCC are controversial and need further evaluation. Early results of chemoimmunotherapy are encouraging...
  10. ncbi request reprint Current therapy of hilar cholangiocarcinoma
    Stephanie Hiu Yan Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    Hepatobiliary Pancreat Dis Int 11:12-7. 2012
    ..Hilar cholangiocarcinoma (HC) is an adenocarcinoma of the extrahepatic biliary tree arising from the main left or right hepatic ducts or their confluence. This tumor is still considered to be difficult to treat or to cure...
  11. ncbi request reprint History of treatment of groin hernia
    W Y Lau
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    World J Surg 26:748-59. 2002
    ....
  12. ncbi request reprint Adjuvant intra-arterial iodine-131-labeled lipiodol for resectable hepatocellular carcinoma: a prospective randomized trial-update on 5-year and 10-year survival
    Wan Yee Lau
    Department of Surgery, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    Ann Surg 247:43-8. 2008
    ..This study evaluated the long-term outcome...
  13. ncbi request reprint Classification of iatrogenic bile duct injury
    Wan Yee Lau
    Department of Surgery, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    Hepatobiliary Pancreat Dis Int 6:459-63. 2007
    ..The ease of management, operative risk, and outcome of bile duct injuries vary considerably, and are highly dependent on the type of injury and its location. This article reviews the various classification systems of bile duct injury...
  14. ncbi request reprint Surgical practice in Hong Kong
    W Y Lau
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories
    Surgeon 4:259-64. 2006
    ..The surgical service in Hong Kong will need to continue to change to meet the new challenges in the future..
  15. ncbi request reprint Perforated peptic ulcer: open versus laparoscopic repair
    W Y Lau
    Department of Surgery, The Chinese University of Hong Kong, Shatin, Hong Kong
    Asian J Surg 25:267-9. 2002
  16. pmc Percutaneous local ablative therapy for hepatocellular carcinoma: a review and look into the future
    W Y Lau
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Ann Surg 237:171-9. 2003
    ..To review and compare treatment result for percutaneous local ablative therapy (PLAT) with surgical resection in the treatment of small hepatocellular carcinoma (HCC)...
  17. ncbi request reprint Salvage surgery following downstaging of unresectable hepatocellular carcinoma--a strategy to increase resectability
    Wan Yee Lau
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, SAR, China
    Ann Surg Oncol 14:3301-9. 2007
    ..However, the resectability of HCC at the time of diagnosis is low (10-30%). This article reviews the use of salvage surgery following tumor downstaging to treat unresectable HCC...
  18. ncbi request reprint The current role of neoadjuvant/adjuvant/chemoprevention therapy in partial hepatectomy for hepatocellular carcinoma: a systematic review
    Wan Yee Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    Hepatobiliary Pancreat Dis Int 8:124-33. 2009
    ..This article systematically reviewed the current evidence of neoadjuvant, adjuvant, and chemoprevention in partial hepatectomy of HCC...
  19. doi request reprint Current role of selective internal irradiation with yttrium-90 microspheres in the management of hepatocellular carcinoma: a systematic review
    Wan Yee Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    Int J Radiat Oncol Biol Phys 81:460-7. 2011
    ..This article reviews the role of selective internal irradiation (SIR) with yttrium-90 ((90)Y) microspheres for hepatocellular carcinoma (HCC)...
  20. pmc Preoperative systemic chemoimmunotherapy and sequential resection for unresectable hepatocellular carcinoma
    W Y Lau
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China
    Ann Surg 233:236-41. 2001
    ..To examine the surgical and pathologic findings of 15 patients who had initially unresectable hepatocellular carcinoma (HCC) and received preoperative systemic chemoimmunotherapy and sequential resection...
  21. doi request reprint Management of bile duct injury after laparoscopic cholecystectomy: a review
    Wan Yee Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    ANZ J Surg 80:75-81. 2010
    ..The aim of this article was to review the management of bile duct injury after cholecystectomy...
  22. ncbi request reprint Methods of vascular control technique during liver resection: a comprehensive review
    Wan Yee Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    Hepatobiliary Pancreat Dis Int 9:473-81. 2010
    ..Hepatic vascular occlusion is effective in minimizing bleeding during hepatic parenchymal transection. This article aimed to review the current role and status of various techniques of hepatic vascular occlusion during hepatic resection...
  23. ncbi request reprint Outcome of lamivudine resistant hepatitis B virus mutant post-liver transplantation on lamivudine monoprophylaxis
    Henry Lik Yuen Chan
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong SAR, China
    Clin Transplant 18:295-300. 2004
    ..We aimed to investigate the clinical outcome of patients who develop lamivudine resistant hepatitis B virus mutants (YMDD mutants) after liver transplantation...
  24. pmc Salvage surgery following downstaging of unresectable hepatocellular carcinoma
    Wan Yee Lau
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR, China
    Ann Surg 240:299-305. 2004
    ..We reported here a series of 49 patients with unresectable hepatocellular carcinoma (HCC) who underwent nonsurgical treatment to downstage the disease followed by salvage surgery, their long-term outcome, and pattern of recurrence...
  25. ncbi request reprint Frequent p15 promoter methylation in tumor and peripheral blood from hepatocellular carcinoma patients
    I H Wong
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong SAR
    Clin Cancer Res 6:3516-21. 2000
    ..The combination of these epigenetic markers may prove valuable for noninvasive HCC diagnosis and disease monitoring...
  26. ncbi request reprint Identification of four distinct regions of allelic imbalances on chromosome 1 by the combined comparative genomic hybridization and microsatellite analysis on hepatocellular carcinoma
    Thomas H Y Leung
    Department of Clinical Oncology, Sir Y K Pao Centre for Cancer, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Mod Pathol 15:1213-20. 2002
    ..The SORs delineated should provide basis for further molecular investigation in hepatocarcinogenesis on genes residing on these chromosomal regions...
  27. pmc Semiquantification of circulating hepatocellular carcinoma cells by reverse transcriptase polymerase chain reaction
    I H Wong
    Department of Clinical Oncology, Sir YK Pao Cancer Centre, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin
    Br J Cancer 76:628-33. 1997
    ..In addition, no significant linear association between the levels of afp mRNA and serum AFP was observed. Semiquantification of both mRNA markers for HCC cell detection may prove useful in prediction of metastases...
  28. ncbi request reprint Circulating tumor cell mRNAs in peripheral blood from hepatocellular carcinoma patients under radiotherapy, surgical resection or chemotherapy: a quantitative evaluation
    I H Wong
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Cancer Lett 167:183-91. 2001
    ..In conjunction with the serum alpha-fetoprotein test, sequential afp-mRNA quantification could predict clinical metastasis/recurrence in 56% of patients during a 4-year follow-up...
  29. ncbi request reprint High incidence of incidental hepatocellular carcinoma exists among hepatitic explanted livers
    A K K Chui
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Transplant Proc 35:350-1. 2003
  30. ncbi request reprint Spontaneous rupture of hepatocellular carcinoma: a systematic review
    Eric C H Lai
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong
    Arch Surg 141:191-8. 2006
    ..To review the management of spontaneous ruptured hepatocellular carcinoma in the acute phase, the definitive treatment after hemostasis, and the prognosis...
  31. ncbi request reprint The continuing challenge of hepatic cancer in Asia
    E C H Lai
    Department of Surgery, Prince of Wales Hospital, Hong Kong SAR, China
    Surgeon 3:210-5. 2005
    ..This article aims to discuss the development and challenges in the prevention and management of HCC in Asia...
  32. ncbi request reprint What determines survival duration in hepatocellular carcinoma treated with intraarterial Yttrium-90 microspheres?
    W Y Lau
    Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Hepatogastroenterology 48:338-40. 2001
    ..The survival duration of patients with nonresectable hepatocellular carcinoma confined to the liver and treated with intraarterial yttrium-90 microspheres was highly variable...
  33. ncbi request reprint Identification of hepatitis B virus X gene mutation in Hong Kong patients with hepatocellular carcinoma
    G G Chen
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Room 306 Cancer Center, Shatin, New Territories, Hong Kong
    J Clin Virol 34:7-12. 2005
    ..Chronic infection by hepatitis B virus (HBV) is the leading cause of hepatocellular carcinoma (HCC) in man. The viral transactivator HBV X (HBx) gene plays a critical role in the molecular pathogenesis of HBV-related HCC...
  34. ncbi request reprint Correlates for a low ankle-brachial index in elderly Chinese
    J Woo
    Department of Medicine and Therapeutics, School of Public Health, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong
    Atherosclerosis 186:360-6. 2006
    ..Lifestyle factors and the female gender were independent risk factors for atherosclerosis in the elderly Chinese population...
  35. ncbi request reprint Nutrient intake and psychological health in an elderly Chinese population
    J Woo
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong
    Int J Geriatr Psychiatry 21:1036-43. 2006
    ..Associations between nutrition and cognitive impairment, and nutrition and depression, have been observed. Elderly people are at risk of under nutrition, and also have higher prevalence of cognitive impairment and depression...
  36. ncbi request reprint Absence of impact of donor hepatic steatosis and posttransplantation lamivudine resistance in a patient with chronic hepatitis B
    H L Y Chan
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong, China
    Transplant Proc 36:2309-10. 2004
    ..Lamivudine monoprophylaxis for hepatitis B virus-related liver diseases post liver transplantation can be used in areas where hepatitis B immunoglobulin is not affordable...
  37. ncbi request reprint Critical graft size and functional recovery in living donor liver transplantation
    A K K Chui
    Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China
    Transplant Proc 36:2277-8. 2004
    ..001 as compared to the cadaveric transplant group). Small-for-size graft syndrome can be avoided if GRWR > 1%, but often occurs when GRWR < 0.8%. Graft function in LDLT recovers more slowly than in cadaveric liver transplant...
  38. ncbi request reprint Multimodality tumor control and living donor transplantation for unresectable hepatocellular carcinoma
    A K K Chui
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong, China
    Transplant Proc 36:2287-8. 2004
    ..If a suitable live donor is not available, aggressive multimodality therapy is recommended while waiting for cadaveric LT...
  39. ncbi request reprint Frequent allelic loss on chromosome 9 in hepatocellular carcinoma
    C T Liew
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Faculty of Medicine, Chinese University of Hong Kong, Shatin
    Int J Cancer 81:319-24. 1999
    ..Our data also suggest that inactivation of the p16 and the p15 genes and the possibility of other unknown tumor-suppressor genes located on these defined deleted regions of chromosome 9 may be involved in the pathogenesis of HCC...
  40. ncbi request reprint Immunohistochemical analysis of pro-apoptotic Bid level in chronic hepatitis, hepatocellular carcinoma and liver metastases
    G G Chen
    Department of Surgery, Room 306, Cancer Center, Prince of Wales Hospital, The Chinese University of Hong Kong, Shantin, N T Hong Kong
    Cancer Lett 172:75-82. 2001
    ..The existence of gradient tumor-development center in chronic hepatitis, liver cirrhosis and non-tumorous tissues from HCC may serve as a pathologic marker of a carcinogenic change of cell phenotypes...
  41. pmc Hypomethylation of chromosome 1 heterochromatin DNA correlates with q-arm copy gain in human hepatocellular carcinoma
    N Wong
    Department of Clinical Oncology, Sir Y K Pao Centre for Cancer, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Am J Pathol 159:465-71. 2001
    ..Our findings suggest a role for Sat2 demethylation in the early stages of the stepwise progression of liver carcinogenesis...
  42. ncbi request reprint Complications of liver donation for living related liver transplantation
    A R N Rao
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China
    Transplant Proc 36:2224-5. 2004
    ..5%) had a morbidity requiring intervention. In conclusion, with meticulous preoperative, intraoperative, and postoperative management, successful LRLT can be performed with minimal donor morbidities...
  43. ncbi request reprint Hematogenous dissemination of hepatocytes and tumor cells after surgical resection of hepatocellular carcinoma: a quantitative analysis
    I H Wong
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region
    Clin Cancer Res 5:4021-7. 1999
    ..Sequential quantification of both alb and afp mRNAs may provide insights for risk assessment and prognostic indication...
  44. ncbi request reprint The cost of palliative care for hepatocellular carcinoma in Hong Kong
    A T Chan
    Department of Clinical Oncology, Sir YK Pao Cancer Centre, Chinese University of Hong Kong, Prince of Wales Hospital
    Pharmacoeconomics 19:947-53. 2001
    ..Hepatocellular carcinoma (HCC) is endemic in parts of Asia and Africa and most patients are not suitable for treatment with a curative approach. Little is known about the cost of palliative care for HCC...
  45. doi request reprint Biliary complications associated with selective internal radiation (SIR) therapy for unresectable liver malignancies
    Simon S M Ng
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    Dig Dis Sci 53:2813-7. 2008
    ..Ultrasonography showed no biliary dilatation, and endoscopic retrograde cholangiopancreatography demonstrated a normal biliary tree. Liver biopsy subsequently confirmed radiation-induced cholangitis...
  46. ncbi request reprint Construction of the Chinese University Prognostic Index for hepatocellular carcinoma and comparison with the TNM staging system, the Okuda staging system, and the Cancer of the Liver Italian Program staging system: a study based on 926 patients
    Thomas W T Leung
    Department of Clinical Oncology, The Chinese University of Hong Kong, Hong Kong SAR, China
    Cancer 94:1760-9. 2002
    ....
  47. ncbi request reprint Decreased expression of Bid in human hepatocellular carcinoma is related to hepatitis B virus X protein
    G G Chen
    Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, N T, Hong Kong
    Eur J Cancer 37:1695-702. 2001
    ..Therefore, this study suggests that a deficiency in the expression of Bid may contribute to the development of such an imbalance in HCC...
  48. ncbi request reprint Complete pathological remission is possible with systemic combination chemotherapy for inoperable hepatocellular carcinoma
    T W Leung
    Department of Clinical Oncology, The Chinese University of Hong Kong, Shatin, New Territories
    Clin Cancer Res 5:1676-81. 1999
    ..Complete pathological remission is possible with this systemic combination. Apparently, persistent radiological lesions may still represent complete pathological resolution of active disease...
  49. ncbi request reprint In vivo trial comparing patients' tolerance of Q-switched Alexandrite (QS Alex) and Q-switched neodymium:yttrium-aluminum-garnet (QS Nd:YAG) lasers in the treatment of nevus of Ota
    H H Chan
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Shatin, Republic of China
    Lasers Surg Med 24:24-8. 1999
    ..The aim of the present study was to compare the patient tolerance of Q-switched Alexandrite (QS Alex) and Q-switched neodymium:yttrium-aluminum-garnet (QS Nd:YAG) lasers in the treatment of nevus of Ota...
  50. ncbi request reprint Quantitative comparison of alpha-fetoprotein and albumin mRNA levels in hepatocellular carcinoma/adenoma, non-tumor liver and blood: implications in cancer detection and monitoring
    I H Wong
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, New Territories, Shatin, Hong Kong
    Cancer Lett 156:141-9. 2000
    ..This approach may prove useful for detecting and monitoring HCC progression...
  51. ncbi request reprint Ex situ ex vivo liver resection, partial liver autotransplantation for advanced hilar cholangiocarcinoma: a case report
    A K K Chui
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Sha Tin, Hong Kong
    Transplant Proc 35:402-3. 2003
  52. ncbi request reprint "No-exclusion criteria" for donor referral and utilization of marginal donors-positive effects on liver transplantation in Hong Kong
    A K K Chui
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Transplant Proc 35:362-3. 2003
  53. ncbi request reprint Liver transplantation for hepatocellular carcinoma in cirrhotic patients-a single-center experience
    A K K Chui
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Transplant Proc 35:379-80. 2003
  54. ncbi request reprint Immunosuppression with rapid steriod reduction among predominantly HBV liver transplantation recipients: initial experience
    A K K Chui
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, SAR, Shatin, Hong Kong, China
    Transplant Proc 35:419-20. 2003
  55. pmc Treatment of inoperable hepatocellular carcinoma with intrahepatic arterial yttrium-90 microspheres: a phase I and II study
    W Y Lau
    Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories
    Br J Cancer 70:994-9. 1994
    ..2 weeks). This difference is statistically significant with P = 0.005. We conclude that yttrium-90 microsphere therapy is safe and that tumour response is dose related. A tumour dose of > 120 Gy is recommended...
  56. ncbi request reprint Hepatic venous outflow obstruction after piggyback liver transplantation by an unusual mechanism: report of a case
    Simon Siu Man Ng
    Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China
    World J Gastroenterol 12:5416-8. 2006
    ..Percutaneous balloon angioplasty is a safe and effective treatment modality for anastomotic stenosis...
  57. ncbi request reprint Consistent chromosome 10 rearrangements in four newly established human hepatocellular carcinoma cell lines
    Elizabeth Pang
    Department of Clinical Oncology, Sir Y K Pao Centre for Cancer, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, N T, SAR Hong Kong, China
    Genes Chromosomes Cancer 33:150-9. 2002
    ....
  58. ncbi request reprint Factors associated with viral breakthrough in lamivudine monoprophylaxis of hepatitis B virus recurrence after liver transplantation
    Henry Lik Yuen Chan
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong
    J Med Virol 68:182-7. 2002
    ..In conclusion, patients transplanted for fulminant hepatitis B and cirrhotic patients in whom HBV DNA could be rendered PCR negative before liver transplantation are unlikely to develop YMDD mutation on lamivudine monoprophylaxis...
  59. ncbi request reprint Human liver regeneration: hepatic energy economy is less efficient when the organ is diseased
    D V Mann
    Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Hepatology 34:557-65. 2001
    ..These findings may explain the mechanism of posthepatectomy liver failure, and offer a rational basis for the assessment of novel hepatic support strategies...
  60. ncbi request reprint Transarterial chemoembolization for hepatocellular carcinoma
    W Y Lau
    Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, HKSAR, China
    J Am Coll Surg 202:155-68. 2006
  61. ncbi request reprint Lymphocyte subsets and natural killer cell cytotoxicity after laparoscopically assisted resection of rectosigmoid carcinoma
    K L Leung
    Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Surg Endosc 17:1305-10. 2003
    ..This study compared the lymphocyte subsets and natural killer (NK) cell cytotoxicity in patients after laparoscopically assisted resection with those after open resection of rectosigmoid carcinoma...
  62. ncbi request reprint Predicting mortality and morbidity of patients operated on for perforated peptic ulcers
    F Y Lee
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
    Arch Surg 136:90-4. 2001
    ..CONCLUSIONS: The APACHE II score may be a useful tool for stratifying patients into various risk groups, and the Boey score might select appropriate patients for laparoscopic repair...
  63. pmc 'Hepatoma-specific' alphafetoprotein may permit preclinical diagnosis of malignant change in patients with chronic liver disease
    P J Johnson
    Hepatoma Study Group, Sir YK Pao Cancer Centre, Shatin, NT, Hong Kong
    Br J Cancer 75:236-40. 1997
    ....
  64. pmc Isoelectric focusing of alphafetoprotein in patients with hepatocellular carcinoma--frequency of specific banding patterns at non-diagnostic serum levels
    S Ho
    Department of Clinical Oncology, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories
    Br J Cancer 73:985-8. 1996
    ..Bands that are characteristic of hepatocellular carcinoma (bands +II or +III) are seen in the great majority of hepatocellular carcinoma patients; their absence makes a diagnosis of hepatocellular carcinoma extremely unlikely...
  65. ncbi request reprint US-guided percutaneous biopsy of small (< or = 1-cm) hepatic lesions
    S C Yu
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, New Territories, Hong Kong
    Radiology 218:195-9. 2001
    ..To determine the accuracy of ultrasonography (US)-guided percutaneous biopsy in diagnosing malignant neoplasms for hepatic lesions 1 cm or smaller...
  66. ncbi request reprint Incidence of deep vein thrombosis after colorectal surgery in a Chinese population
    F Y Lee
    Department of Surgery and Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Shatin, Hong Kong
    ANZ J Surg 71:637-40. 2001
    ..CONCLUSION: A high incidence of asymptomatic calf vein thrombosis occurred after colorectal surgery for malignancies in Chinese. The majority did not progress even without anticoagulation...
  67. pmc Biliary drainage for obstructive jaundice enhances hepatic energy status in humans: a 31-phosphorus magnetic resonance spectroscopy study
    D V Mann
    Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Gut 50:118-22. 2002
    ..Biliary obstruction impairs liver function although the pathophysiological mechanism is incompletely understood...
  68. doi request reprint Treatment of unresectable hepatocellular carcinoma with transarterial radioembolization: iodine-131-lipiodol
    W Y Lau
    Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    ANZ J Surg 78:331-2. 2008
  69. ncbi request reprint The longest survivor and first potential cure of an advanced cholangiocarcinoma by ex vivo resection and autotransplantation: a case report and review of the literature
    A K K Chui
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Am Surg 69:441-4. 2003
    ..MRI and CT examinations done over the subsequent 17 months showed no evidence of recurrence. In conclusion ex vivo liver resection and Atx can be a viable option for cure among highly selected patients with CC...
  70. pmc Soft-tissue case 52. Hepatocellular carcinoma with tumour cast in the biliary tree
    Eric C H Lai
    Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    Can J Surg 46:301-2, 311. 2003
  71. ncbi request reprint Does patient position during liver surgery influence the risk of venous air embolism?
    C A Moulton
    Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Sha Tin, New Territories, Hong Kong, China
    Am J Surg 181:366-7. 2001
    ..It is generally believed that positioning of the patient in a head-down tilt (Trendelenberg position) decreases the likelihood of a venous air embolism during liver resection...
  72. ncbi request reprint Synchronous laparoscopic-assisted right hemicolectomy and right adrenalectomy
    S C K Lam
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing Street, Shatin, NT, Hong Kong
    Surg Endosc 16:1107. 2002
    ..The whole operation lasted 270 min and our patient made an uneventful recovery...
  73. ncbi request reprint Systemic antibiotic regimens for acute cholecystitis treated by early cholecystectomy
    W Y Lau
    Department of Surgery, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories
    Aust N Z J Surg 60:539-43. 1990
    ..05). Also, patients on LC had to stay statistically longer in hospital in order to complete the course of antibiotic (P less than 0.05). We therefore recommend a SC to be used, as it is more cost-effective and causes fewer complications...
  74. doi request reprint Mesohepatectomy for hepatocellular carcinoma: a study of 256 patients
    Xiao Ping Chen
    Department of Surgery, Hepatic Surgery Center and Institute of HBP Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430030 Wuhan, People s Republic of China
    Int J Colorectal Dis 23:543-6. 2008
    ..This retrospective study aimed to evaluate the early results and late survival outcomes of mesohepatectomy in HCC...
  75. ncbi request reprint A new technique of hepatic segmentectomy by selective portal venous occlusion using a balloon catheter through a branch of the superior mesenteric vein
    Jin rui Ou
    Department of Hepatobiliary Surgery, Guangdong Provincial People s Hospital, Guangzhou, People s Republic of China
    World J Surg 31:1240-2. 2007
    ..We describe a new technique of segment-based liver resection by inserting a 6 French balloon catheter into the portal vein via a branch of the superior mesenteric vein...