C B S Lau

Summary

Affiliation: The Chinese University of Hong Kong
Country: China

Publications

  1. doi request reprint Development of a simple chromatographic method for distinguishing between two easily confused species, Hedyotis diffusa and Hedyotis corymbosa
    Clara B S Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Nat Prod Res 26:1446-50. 2012
  2. pmc Osteoprotective effects of Fructus Ligustri Lucidi aqueous extract in aged ovariectomized rats
    Chun Hay Ko
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Chin Med 5:39. 2010
  3. ncbi request reprint Use of dong quai (Angelica sinensis) to treat peri- or postmenopausal symptoms in women with breast cancer: is it appropriate?
    Clara B S Lau
    School of Pharmacy, The Chinese University of Hong Kong, Shatin, NT
    Menopause 12:734-40. 2005
  4. ncbi request reprint Cytotoxic activities of Coriolus versicolor (Yunzhi) extract on human leukemia and lymphoma cells by induction of apoptosis
    C B S Lau
    School of Pharmacy, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Life Sci 75:797-808. 2004
  5. doi request reprint Radix Astragali and Radix Rehmanniae, the principal components of two antidiabetic foot ulcer herbal formulae, elicit viability-promoting effects on primary fibroblasts cultured from diabetic foot ulcer tissues
    T W Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China
    Phytother Res 23:809-15. 2009
  6. ncbi request reprint Pharmacological investigations of the anti-diabetic effect of Cortex Moutan and its active component paeonol
    C H Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    Phytomedicine 14:778-84. 2007
  7. doi request reprint Mechanisms of the cerebral vasodilator actions of isoflavonoids of Gegen on rat isolated basilar artery
    Y Deng
    School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    J Ethnopharmacol 139:294-304. 2012
  8. doi request reprint Pharmacological investigation on the wound healing effects of Radix Rehmanniae in an animal model of diabetic foot ulcer
    T W Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    J Ethnopharmacol 123:155-62. 2009
  9. doi request reprint An in vivo investigation on the wound-healing effect of two medicinal herbs using an animal model with foot ulcer
    T W Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, SAR, China
    Eur Surg Res 41:15-23. 2008
  10. doi request reprint In vitro antidiabetic activities of five medicinal herbs used in Chinese medicinal formulae
    C H Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China
    Phytother Res 22:1384-8. 2008

Collaborators

Detail Information

Publications26

  1. doi request reprint Development of a simple chromatographic method for distinguishing between two easily confused species, Hedyotis diffusa and Hedyotis corymbosa
    Clara B S Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Nat Prod Res 26:1446-50. 2012
    ..In conclusion, a quick and simple TLC assay was conducted to distinguish between the two species H. diffusa and H. corymbosa...
  2. pmc Osteoprotective effects of Fructus Ligustri Lucidi aqueous extract in aged ovariectomized rats
    Chun Hay Ko
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Chin Med 5:39. 2010
    ..The present study investigates the anti-osteoporotic activity of FLL aqueous extract in the model of postmenopausal bone loss in aged ovariectomized (OVX) female rats...
  3. ncbi request reprint Use of dong quai (Angelica sinensis) to treat peri- or postmenopausal symptoms in women with breast cancer: is it appropriate?
    Clara B S Lau
    School of Pharmacy, The Chinese University of Hong Kong, Shatin, NT
    Menopause 12:734-40. 2005
    ....
  4. ncbi request reprint Cytotoxic activities of Coriolus versicolor (Yunzhi) extract on human leukemia and lymphoma cells by induction of apoptosis
    C B S Lau
    School of Pharmacy, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Life Sci 75:797-808. 2004
    ..The CV extract was found to selectively and dose-dependently inhibit the proliferation of lymphoma and leukemic cells possibly via an apoptosis-dependent pathway...
  5. doi request reprint Radix Astragali and Radix Rehmanniae, the principal components of two antidiabetic foot ulcer herbal formulae, elicit viability-promoting effects on primary fibroblasts cultured from diabetic foot ulcer tissues
    T W Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China
    Phytother Res 23:809-15. 2009
    ..The results in this study indicate that fibroblast viability enhancement effects of RA and RR likely underlie the healing effects of F1 and F2 in diabetic foot ulcers...
  6. ncbi request reprint Pharmacological investigations of the anti-diabetic effect of Cortex Moutan and its active component paeonol
    C H Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    Phytomedicine 14:778-84. 2007
    ..With neonatal-streptozotocin diabetic rats, paeonol (200 and 400mg/kgbody wt.) was found to improve oral glucose tolerance in vivo. To the best of our knowledge, this is the first report on the anti-diabetic effect of paeonol...
  7. doi request reprint Mechanisms of the cerebral vasodilator actions of isoflavonoids of Gegen on rat isolated basilar artery
    Y Deng
    School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    J Ethnopharmacol 139:294-304. 2012
    ..In this study, the relaxant actions of three of its isoflavonoids; puerarin, daidzein, and daidzin, were investigated on rat-isolated cerebral basilar artery...
  8. doi request reprint Pharmacological investigation on the wound healing effects of Radix Rehmanniae in an animal model of diabetic foot ulcer
    T W Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    J Ethnopharmacol 123:155-62. 2009
    ..Radix Rehmanniae (RR) has a very long history of usage in traditional Chinese medicine and is usually one of the principal herb found in many herbal formulae used in diabetic foot ulcer...
  9. doi request reprint An in vivo investigation on the wound-healing effect of two medicinal herbs using an animal model with foot ulcer
    T W Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, SAR, China
    Eur Surg Res 41:15-23. 2008
    ..With the aim to study the efficacy of two commonly used herbs for ulcer healing, namely Radix Astragali and Radix Rehmanniae, a good animal model needs to be developed for a proper in vivo investigation...
  10. doi request reprint In vitro antidiabetic activities of five medicinal herbs used in Chinese medicinal formulae
    C H Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China
    Phytother Res 22:1384-8. 2008
    ..In conclusion, the five herbs exhibited distinct antidiabetic mechanisms in vitro and hence our investigations provided scientific evidence to support the traditional usage of these herbs for diabetic treatment in medicinal formulae...
  11. ncbi request reprint Investigation of the effects of Chinese medicine on fibroblast viability: implications in wound healing
    T W Lau
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N T, Hong Kong, China
    Phytother Res 21:938-47. 2007
    ..These results further support the previously reported clinical efficacies of the two formulae on healing diabetic foot ulcers...
  12. ncbi request reprint Cerebral vasodilator properties of Danshen and Gegen: a study of their combined efficacy and mechanisms of actions
    Y Deng
    School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong Special Administrative Region
    Phytomedicine 21:391-9. 2014
    ..It is suspected that the cerebral vasodilator effects of Danshen and Gegen produced either on their own or in combination, can help patients with obstructive cerebrovascular diseases. ..
  13. doi request reprint The anti-hypertensive effect of Danshen (Salvia miltiorrhiza) and Gegen (Pueraria lobata) formula in rats and its underlying mechanisms of vasorelaxation
    C F Ng
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    J Ethnopharmacol 137:1366-72. 2011
    ..Radix Salviae miltiorrhizae (Danshen) and Radix Puerariae lobatae (Gegen) have long been used in traditional Chinese Medicine and serve as the principal herbs in treating cardiovascular disease...
  14. ncbi request reprint Influence of an anti-diabetic foot ulcer formula and its component herbs on tissue and systemic glucose homeostasis
    C M Chan
    Department of Biochemistry, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China
    J Ethnopharmacol 109:10-20. 2007
    ....
  15. doi request reprint Enantiospecific synthesis of pseudoacarviosin as a potential antidiabetic agent
    Tony K M Shing
    Department of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Org Lett 10:3145-8. 2008
    ..Pseudoacarviosin 5 has been shown to be a potent inhibitor of alpha-glucosidases, particularly the intestinal mucosal enzymes sucrase and glucoamylase of relevance to blood glucose control...
  16. doi request reprint Mechanisms of the relaxant effect of a danshen and gegen formulation on rat isolated cerebral basilar artery
    F F Y Lam
    School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
    J Ethnopharmacol 132:186-92. 2010
    ..In this study, the actions of a danshen and gegen formulation (DG; ratio 7:3) were investigated on rat-isolated cerebral basilar artery...
  17. ncbi request reprint Immunomodulatory effects of a traditional Chinese medicine with potential antiviral activity: a self-control study
    P M K Poon
    Department of Chemical Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    Am J Chin Med 34:13-21. 2006
    ..The transient increase in CD4/CD8 ratio was likely due to the TCM intake. We postulate that the administration of the innovative TCM may have beneficial immunomodulatory effects for preventing viral infections including SARS...
  18. doi request reprint Search for antimycobacterial constituents from a Tibetan medicinal plant, Gentianopsis paludosa
    Ming Fai Yeung
    School of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong
    Phytother Res 23:123-5. 2009
    ..Compounds 1, 2, 3 and 5 showed modest inhibitory effect against the growth of Mycobacterium smegmatis and M. tuberculosis...
  19. ncbi request reprint Comparative studies of various ganoderma species and their different parts with regard to their antitumor and immunomodulating activities in vitro
    Grace G L Yue
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    J Altern Complement Med 12:777-89. 2006
    ....
  20. pmc Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longa
    Grace G L Yue
    Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Food Chem Toxicol 48:2011-20. 2010
    ..The findings revealed the potential use of CL crude extract (containing curcuminoids and volatile oil including turmerones) as chemopreventive agent...
  21. doi request reprint Simultaneous quantification of active components in the herbs and products of Si-Wu-Tang by high performance liquid chromatography-mass spectrometry
    Zhi Jun Wang
    School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    J Pharm Biomed Anal 50:232-44. 2009
    ..The currently developed method provides a sensitive and rapid quantification approach that can be useful in the quality control of raw herbs and products of SWT...
  22. ncbi request reprint Desoxyrhaponticin (3,5-dihydroxy-4'-methoxystilbene 3-O-beta-D-glucoside) inhibits glucose uptake in the intestine and kidney: In vitro and in vivo studies
    Jian Mei Li
    School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China
    J Pharmacol Exp Ther 320:38-46. 2007
    ..The in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney...
  23. ncbi request reprint Differential effect of Coriolus versicolor (Yunzhi) extract on cytokine production by murine lymphocytes in vitro
    C Y Ho
    School of Pharmacy, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    Int Immunopharmacol 4:1549-57. 2004
    ..The CV extract was suggested to be a lymphocyte mitogen by differentially enhancing the production of Th1-related cytokines...
  24. ncbi request reprint Schizonepeta tenuifolia: chemistry, pharmacology, and clinical applications
    Dennis Fung
    School of Pharmacy, Chinese University of Hong Kong, Shatin, New Territories
    J Clin Pharmacol 42:30-6. 2002
    ..Hence, further studies will be warranted to show its efficacy and safety...