Research Topics
| C B S LauSummaryAffiliation: The Chinese University of Hong Kong Country: China Publications
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Detail Information
Publications
Development of a simple chromatographic method for distinguishing between two easily confused species, Hedyotis diffusa and Hedyotis corymbosaClara B S Lau
Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
Nat Prod Res 26:1446-50. 2012..In conclusion, a quick and simple TLC assay was conducted to distinguish between the two species H. diffusa and H. corymbosa...
Osteoprotective effects of Fructus Ligustri Lucidi aqueous extract in aged ovariectomized ratsChun Hay Ko
Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China
Chin Med 5:39. 2010..The present study investigates the anti-osteoporotic activity of FLL aqueous extract in the model of postmenopausal bone loss in aged ovariectomized (OVX) female rats...
Cytotoxic activities of Coriolus versicolor (Yunzhi) extract on human leukemia and lymphoma cells by induction of apoptosisC B S Lau
School of Pharmacy, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
Life Sci 75:797-808. 2004..The CV extract was found to selectively and dose-dependently inhibit the proliferation of lymphoma and leukemic cells possibly via an apoptosis-dependent pathway...- Use of dong quai (Angelica sinensis) to treat peri- or postmenopausal symptoms in women with breast cancer: is it appropriate?Clara B S Lau
School of Pharmacy, The Chinese University of Hong Kong, Shatin, NT
Menopause 12:734-40. 2005.... - Radix Astragali and Radix Rehmanniae, the principal components of two antidiabetic foot ulcer herbal formulae, elicit viability-promoting effects on primary fibroblasts cultured from diabetic foot ulcer tissuesT W Lau
Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China
Phytother Res 23:809-15. 2009..The results in this study indicate that fibroblast viability enhancement effects of RA and RR likely underlie the healing effects of F1 and F2 in diabetic foot ulcers... - Pharmacological investigations of the anti-diabetic effect of Cortex Moutan and its active component paeonolC H Lau
Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
Phytomedicine 14:778-84. 2007..With neonatal-streptozotocin diabetic rats, paeonol (200 and 400mg/kgbody wt.) was found to improve oral glucose tolerance in vivo. To the best of our knowledge, this is the first report on the anti-diabetic effect of paeonol... - Mechanisms of the cerebral vasodilator actions of isoflavonoids of Gegen on rat isolated basilar arteryY Deng
School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
J Ethnopharmacol 139:294-304. 2012..In this study, the relaxant actions of three of its isoflavonoids; puerarin, daidzein, and daidzin, were investigated on rat-isolated cerebral basilar artery... - Pharmacological investigation on the wound healing effects of Radix Rehmanniae in an animal model of diabetic foot ulcerT W Lau
Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
J Ethnopharmacol 123:155-62. 2009..Radix Rehmanniae (RR) has a very long history of usage in traditional Chinese medicine and is usually one of the principal herb found in many herbal formulae used in diabetic foot ulcer... - An in vivo investigation on the wound-healing effect of two medicinal herbs using an animal model with foot ulcerT W Lau
Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, SAR, China
Eur Surg Res 41:15-23. 2008..With the aim to study the efficacy of two commonly used herbs for ulcer healing, namely Radix Astragali and Radix Rehmanniae, a good animal model needs to be developed for a proper in vivo investigation... - In vitro antidiabetic activities of five medicinal herbs used in Chinese medicinal formulaeC H Lau
Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China
Phytother Res 22:1384-8. 2008..In conclusion, the five herbs exhibited distinct antidiabetic mechanisms in vitro and hence our investigations provided scientific evidence to support the traditional usage of these herbs for diabetic treatment in medicinal formulae... - Investigation of the effects of Chinese medicine on fibroblast viability: implications in wound healingT W Lau
Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, N T, Hong Kong, China
Phytother Res 21:938-47. 2007..These results further support the previously reported clinical efficacies of the two formulae on healing diabetic foot ulcers... - The anti-hypertensive effect of Danshen (Salvia miltiorrhiza) and Gegen (Pueraria lobata) formula in rats and its underlying mechanisms of vasorelaxationC F Ng
Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
J Ethnopharmacol 137:1366-72. 2011..Radix Salviae miltiorrhizae (Danshen) and Radix Puerariae lobatae (Gegen) have long been used in traditional Chinese Medicine and serve as the principal herbs in treating cardiovascular disease... - Influence of an anti-diabetic foot ulcer formula and its component herbs on tissue and systemic glucose homeostasisC M Chan
Department of Biochemistry, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, China
J Ethnopharmacol 109:10-20. 2007.... - Enantiospecific synthesis of pseudoacarviosin as a potential antidiabetic agentTony K M Shing
Department of Chemistry, The Chinese University of Hong Kong, Shatin, Hong Kong, China
Org Lett 10:3145-8. 2008..Pseudoacarviosin 5 has been shown to be a potent inhibitor of alpha-glucosidases, particularly the intestinal mucosal enzymes sucrase and glucoamylase of relevance to blood glucose control... - Mechanisms of the relaxant effect of a danshen and gegen formulation on rat isolated cerebral basilar arteryF F Y Lam
School of Biomedical Sciences, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
J Ethnopharmacol 132:186-92. 2010..In this study, the actions of a danshen and gegen formulation (DG; ratio 7:3) were investigated on rat-isolated cerebral basilar artery... - Immunomodulatory effects of a traditional Chinese medicine with potential antiviral activity: a self-control studyP M K Poon
Department of Chemical Pathology, The Chinese University of Hong Kong, Shatin, Hong Kong, China
Am J Chin Med 34:13-21. 2006..The transient increase in CD4/CD8 ratio was likely due to the TCM intake. We postulate that the administration of the innovative TCM may have beneficial immunomodulatory effects for preventing viral infections including SARS... - Comparative studies of various ganoderma species and their different parts with regard to their antitumor and immunomodulating activities in vitroGrace G L Yue
Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China
J Altern Complement Med 12:777-89. 2006..To the best of the authors' knowledge, this is the first detailed comparison among the different parts of the fruiting bodies of Ganoderma... - Search for antimycobacterial constituents from a Tibetan medicinal plant, Gentianopsis paludosaMing Fai Yeung
School of Chinese Medicine, The Chinese University of Hong Kong, Hong Kong
Phytother Res 23:123-5. 2009..Compounds 1, 2, 3 and 5 showed modest inhibitory effect against the growth of Mycobacterium smegmatis and M. tuberculosis... - Evaluation of in vitro anti-proliferative and immunomodulatory activities of compounds isolated from Curcuma longaGrace G L Yue
Institute of Chinese Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
Food Chem Toxicol 48:2011-20. 2010..The findings revealed the potential use of CL crude extract (containing curcuminoids and volatile oil including turmerones) as chemopreventive agent... - Desoxyrhaponticin (3,5-dihydroxy-4'-methoxystilbene 3-O-beta-D-glucoside) inhibits glucose uptake in the intestine and kidney: In vitro and in vivo studiesJian Mei Li
School of Chinese Medicine, The Chinese University of Hong Kong, Shatin, Hong Kong, China
J Pharmacol Exp Ther 320:38-46. 2007..The in vivo antidiabetic action of this compound can be explained, in part at least, by inhibition of glucose transport in the small intestine and inhibition of glucose reabsorption in the kidney... - Simultaneous quantification of active components in the herbs and products of Si-Wu-Tang by high performance liquid chromatography-mass spectrometryZhi Jun Wang
School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
J Pharm Biomed Anal 50:232-44. 2009..The currently developed method provides a sensitive and rapid quantification approach that can be useful in the quality control of raw herbs and products of SWT... - Differential effect of Coriolus versicolor (Yunzhi) extract on cytokine production by murine lymphocytes in vitroC Y Ho
School of Pharmacy, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
Int Immunopharmacol 4:1549-57. 2004..The CV extract was suggested to be a lymphocyte mitogen by differentially enhancing the production of Th1-related cytokines... - Schizonepeta tenuifolia: chemistry, pharmacology, and clinical applicationsDennis Fung
School of Pharmacy, Chinese University of Hong Kong, Shatin, New Territories
J Clin Pharmacol 42:30-6. 2002..Hence, further studies will be warranted to show its efficacy and safety...