Kam Chuen Lai

Summary

Affiliation: The University of Hong Kong
Country: China

Publications

  1. ncbi request reprint Esomeprazole with aspirin versus clopidogrel for prevention of recurrent gastrointestinal ulcer complications
    Kam Chuen Lai
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Clin Gastroenterol Hepatol 4:860-5. 2006
  2. ncbi request reprint Effect of treatment of Helicobacter pylori on the prevention of gastroduodenal ulcers in patients receiving long-term NSAIDs: a double-blind, placebo-controlled trial
    K C Lai
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Aliment Pharmacol Ther 17:799-805. 2003
  3. ncbi request reprint Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use
    Kam Chuen Lai
    Departments of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    N Engl J Med 346:2033-8. 2002
  4. ncbi request reprint Lansoprazole reduces ulcer relapse after eradication of Helicobacter pylori in nonsteroidal anti-inflammatory drug users--a randomized trial
    K C Lai
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Aliment Pharmacol Ther 18:829-36. 2003
  5. ncbi request reprint Celecoxib compared with lansoprazole and naproxen to prevent gastrointestinal ulcer complications
    Kam Chuen Lai
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Am J Med 118:1271-8. 2005
  6. ncbi request reprint Low-dose rabeprazole, amoxicillin and metronidazole triple therapy for the treatment of Helicobacter pylori infection in Chinese patients
    Wai Man Wong
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Pokfulam Road, Hong Kong
    J Gastroenterol Hepatol 20:935-40. 2005
  7. ncbi request reprint Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial
    Benjamin Chun Yu Wong
    Department of Medicine, University of Hong Kong, Hong Kong, China
    JAMA 291:187-94. 2004
  8. ncbi request reprint Antralization at the edge of proximal gastric ulcers: does Helicobacter pylori infection play a role?
    Harry Hua Xinag Xia
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    World J Gastroenterol 9:1265-9. 2003
  9. ncbi request reprint Colonoscopy demand and practice in a regional hospital over 9 years in Hong Kong: resource implication for cancer screening
    Annie O O Chan
    Department of Medicine, University of Hong Kong, SAR, China
    Digestion 73:84-8. 2006
  10. ncbi request reprint Incidence and predictors of upper gastrointestinal bleeding in patients receiving low-dose aspirin for secondary prevention of cardiovascular events in patients with coronary artery disease
    William Ng
    Division of Cardiology, University Department of Medicine, Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China
    World J Gastroenterol 12:2923-7. 2006

Detail Information

Publications63

  1. ncbi request reprint Esomeprazole with aspirin versus clopidogrel for prevention of recurrent gastrointestinal ulcer complications
    Kam Chuen Lai
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Clin Gastroenterol Hepatol 4:860-5. 2006
    ..We tested the hypothesis that clopidogrel is as effective as esomeprazole and aspirin in preventing recurrences of ulcer complications...
  2. ncbi request reprint Effect of treatment of Helicobacter pylori on the prevention of gastroduodenal ulcers in patients receiving long-term NSAIDs: a double-blind, placebo-controlled trial
    K C Lai
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Aliment Pharmacol Ther 17:799-805. 2003
    ..There is controversy as to whether Helicobacter pylori and non-steroidal anti-inflammatory drugs interact to cause peptic ulcers...
  3. ncbi request reprint Lansoprazole for the prevention of recurrences of ulcer complications from long-term low-dose aspirin use
    Kam Chuen Lai
    Departments of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    N Engl J Med 346:2033-8. 2002
    ..The role of gastric acid suppression in preventing the recurrence of ulcer complications after the eradication of Helicobacter pylori infection in patients taking long-term low-dose aspirin is uncertain...
  4. ncbi request reprint Lansoprazole reduces ulcer relapse after eradication of Helicobacter pylori in nonsteroidal anti-inflammatory drug users--a randomized trial
    K C Lai
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Aliment Pharmacol Ther 18:829-36. 2003
    ..To study whether prophylaxis with lansoprazole could prevent relapse of ulcers after eradication of Helicobacter pylori in patients with NSAID-related peptic ulcers...
  5. ncbi request reprint Celecoxib compared with lansoprazole and naproxen to prevent gastrointestinal ulcer complications
    Kam Chuen Lai
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Am J Med 118:1271-8. 2005
    ..We compared the efficacy of a selective COX-2 inhibitor with that of proton pump inhibitor co-therapy in the reduction in the incidence of ulcer relapse in patients with a history of NSAID-related peptic ulcers...
  6. ncbi request reprint Low-dose rabeprazole, amoxicillin and metronidazole triple therapy for the treatment of Helicobacter pylori infection in Chinese patients
    Wai Man Wong
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Pokfulam Road, Hong Kong
    J Gastroenterol Hepatol 20:935-40. 2005
    ..The effects were compared of 7-day low-dose and high dose rabeprazole in RAM for the primary treatment of H. pylori infection in Chinese patients...
  7. ncbi request reprint Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial
    Benjamin Chun Yu Wong
    Department of Medicine, University of Hong Kong, Hong Kong, China
    JAMA 291:187-94. 2004
    ..Although chronic Helicobacter pylori infection is associated with gastric cancer, the effect of H pylori treatment on prevention of gastric cancer development in chronic carriers is unknown...
  8. ncbi request reprint Antralization at the edge of proximal gastric ulcers: does Helicobacter pylori infection play a role?
    Harry Hua Xinag Xia
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    World J Gastroenterol 9:1265-9. 2003
    ..To determine the prevalence of antralization at the edge of proximal gastric ulcers, and the effect of H. pylori eradication on the mucosal appearances...
  9. ncbi request reprint Colonoscopy demand and practice in a regional hospital over 9 years in Hong Kong: resource implication for cancer screening
    Annie O O Chan
    Department of Medicine, University of Hong Kong, SAR, China
    Digestion 73:84-8. 2006
    ..The incidence of colorectal cancer (CRC) in Hong Kong is rising. The trend of colonoscopy demand is uncertain...
  10. ncbi request reprint Incidence and predictors of upper gastrointestinal bleeding in patients receiving low-dose aspirin for secondary prevention of cardiovascular events in patients with coronary artery disease
    William Ng
    Division of Cardiology, University Department of Medicine, Queen Mary Hospital, Pokfulam Road, Hong Kong SAR, China
    World J Gastroenterol 12:2923-7. 2006
    ..However, the incidence and predictors of upper gastrointestinal bleeding (UGIB) with its use are unknown. We studied prospectively the incidence and outcome of peptic ulceration in low-dose aspirin users...
  11. ncbi request reprint Effects of primary metronidazole and clarithromycin resistance to Helicobacter pylori on omeprazole, metronidazole, and clarithromycin triple-therapy regimen in a region with high rates of metronidazole resistance
    Wai Man Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Clin Infect Dis 37:882-9. 2003
    ..MtxR and ClaR significantly affected the success of eradication therapy. Posttreatment rates of resistance were high and were related to the presence of pretreatment antibiotic resistance...
  12. ncbi request reprint Prevalence of colorectal neoplasm among patients with newly diagnosed coronary artery disease
    Annie On On Chan
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    JAMA 298:1412-9. 2007
    ..Colorectal neoplasm and coronary artery disease (CAD) share similar risk factors, and their co-occurrence may be associated...
  13. ncbi request reprint Pathophysiology of gastroesophageal reflux diseases in Chinese--role of transient lower esophageal sphincter relaxation and esophageal motor dysfunction
    Wai Man Wong
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Am J Gastroenterol 99:2088-93. 2004
    ..Transient lower esophageal sphincter relaxation (TLESR) is the major mechanism for gastroesophageal reflux in the Western population. The major reflux mechanism in Chinese patients with GERD has not been studied before...
  14. ncbi request reprint Virtual colonoscopy for the detection of colorectal polyps and cancers in a Chinese population
    Benjamin Chun Yu Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    J Gastroenterol Hepatol 17:1323-7. 2002
    ..The aim of this study is to assess the sensitivity of virtual colonoscopy in detecting colorectal polyps and cancers in a Chinese population...
  15. ncbi request reprint Role of cholecystectomy in preventing recurrent cholangitis
    Chee Kin Hui
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Gastrointest Endosc 56:55-60. 2002
    ..The purpose of this study was to analyze the role of elective cholecystectomy in preventing recurrent acute cholangitis in Asian patients...
  16. ncbi request reprint Outpatients undergoing therapeutic endoscopic retrograde cholangiopancreatography: six-hour versus overnight observation
    Chee Kin Hui
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    J Gastroenterol Hepatol 19:1163-8. 2004
    ....
  17. ncbi request reprint Differing coping mechanisms, stress level and anorectal physiology in patients with functional constipation
    Annie Oo Chan
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    World J Gastroenterol 11:5362-6. 2005
    ..To investigate coping mechanisms, constipation symptoms and anorectal physiology in 80 constipated subjects and 18 controls...
  18. ncbi request reprint Does the addition of endoscopic sphincterotomy to stent insertion improve drainage of the bile duct in acute suppurative cholangitis?
    Chee Kin Hui
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Gastrointest Endosc 58:500-4. 2003
    ..The aim of this retrospective study was to determine whether endoscopic sphincterotomy, in addition to an internal endoprosthesis, improves outcome for patients with acute suppurative cholangitis...
  19. ncbi request reprint Accuracy of a new near patient test for the diagnosis of Helicobacter pylori infection in Chinese
    Wai Man Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    J Gastroenterol Hepatol 17:1272-7. 2002
    ..The aim of this study is to evaluate the accuracy of a new near patient test (Signify H. pylori) for the diagnosis of H. pylori and the usefulness of the Signify H. pylori test for a test and treat strategy...
  20. ncbi request reprint The Hong Kong index of dyspepsia: a validated symptom severity questionnaire for patients with dyspepsia
    Wayne H C Hu
    Department of Medicine, University of Hong Kong, China
    J Gastroenterol Hepatol 17:545-51. 2002
    ..Locally validated symptom questionnaires are essential instruments in dyspepsia research. A symptom score for Chinese dyspeptics was developed. Multiple aspects of validity and reliability were assessed...
  21. ncbi request reprint Population based study of noncardiac chest pain in southern Chinese: prevalence, psychosocial factors and health care utilization
    Wai Man Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, China
    World J Gastroenterol 10:707-12. 2004
    ..Population-based assessment of noncardiac chest pain (NCCP) is lacking. The aim of this study was to evaluate the prevalence, psychosocial factors and health seeking behaviour of NCCP in southern Chinese...
  22. ncbi request reprint Pyogenic liver abscess: retrospective analysis of 80 cases over a 10-year period
    Wai Man Wong
    University Department of Medicine, Queen Mary Hospital, University of Hong Kong, China
    J Gastroenterol Hepatol 17:1001-7. 2002
    ..A total of 80 patients with pyogenic liver abscess managed at a single institution over a 10-year period were studied...
  23. ncbi request reprint Self-inflicted rectal ulcer with exuberant granulation tissue: a lesion that mimics carcinoma
    Wai Man Wong
    Department of Medicine and Pathology, Queen Mary Hospital, University of Hong Kong
    Gastrointest Endosc 55:951-2. 2002
  24. ncbi request reprint [13C]-urea breath test without prior fasting and without test meal is accurate for the detection of Helicobacter pylori infection in Chinese
    Fook Hong Ng
    Department of Medicine, Ruttonjee Hospital, Hong Kong
    J Gastroenterol Hepatol 17:834-8. 2002
    ..However, recent studies have suggested that prior fasting and test meal may not be essential. We aimed to determine the accuracy of a new [13C]-UBT protocol without fasting in Chinese...
  25. ncbi request reprint Intestinal tuberculosis mimicking fistulizing Crohn's disease
    Wai Man Wong
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    J Gastroenterol Hepatol 22:137-9. 2007
    ..Gastroenterologists and general physicians should aware of the possibility of intestinal tuberculosis in areas with a high prevalence of tuberculosis infection...
  26. ncbi request reprint Evaluation of an automated immunochemical fecal occult blood test for colorectal neoplasia detection in a Chinese population
    Wai Man Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Cancer 97:2420-4. 2003
    ..Tokyo, Japan), in a Chinese population referred for colonoscopy...
  27. ncbi request reprint A patient with long-standing iron-deficient anemia
    Annie On On Chan
    Department of Medicine, University of Hong Kong, Pokfulam, Hong Kong
    Nat Clin Pract Gastroenterol Hepatol 3:112-6; quiz 117. 2006
    ..She required periodic blood transfusions and iron supplements to maintain her hemoglobin levels. She was subsequently discharged to a family clinic for follow-up until the current presentation...
  28. ncbi request reprint Coexistence between colorectal cancer/adenoma and coronary artery disease: results from 1382 patients
    A O O Chan
    Division of Gastroenterology and Hepatology, Department of Medicine, the University of Hongkong, Hong Kong, China
    Aliment Pharmacol Ther 24:535-9. 2006
    ..Common risk factors exist in colorectal neoplasia (cancer or adenoma) and coronary artery disease...
  29. ncbi request reprint Validated questionnaire on diagnosis and symptom severity for functional constipation in the Chinese population
    A O O Chan
    Department of Medicine, University of Hong Kong, Hong Kong
    Aliment Pharmacol Ther 22:483-8. 2005
    ..Functional constipation is a common problem in clinical practice. No validated questionnaire is available in Chinese...
  30. ncbi request reprint Standard treatment for Helicobacter pylori infection is suboptimal in non-ulcer dyspepsia compared with duodenal ulcer in Chinese
    W M Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Aliment Pharmacol Ther 21:73-81. 2005
    ..Recent studies suggest that the Helicobacter pylori eradication rate in patients with non-ulcer dyspepsia is lower when compared to patients with peptic ulcer diseases...
  31. ncbi request reprint A pilot study of participation in faecal occult blood testing and screening colonoscopy after health education in Hong Kong
    B C Y Wong
    Departments of Medicine 2Clinical Biochemistry, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Eur J Cancer Prev 14:181-4. 2005
    ..In conclusion, health education is important for ensuring high acceptance and implementation of colorectal cancer screening in Hong Kong Chinese. FOBT is an acceptable and feasible screening method in Hong Kong...
  32. ncbi request reprint Optimal serological tests for the detection of Helicobacter pylori infection in the Chinese population
    H H X Xia
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Aliment Pharmacol Ther 16:521-6. 2002
    ..Numerous serological tests for the detection of Helicobacter pylori infection have been developed. However, many perform poorly when evaluated in the Chinese population...
  33. ncbi request reprint Upper gastrointestinal evaluation of Chinese patients with non-cardiac chest pain
    W M Wong
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Aliment Pharmacol Ther 16:465-71. 2002
    ..To test the usefulness of upper gastrointestinal investigations and quality of life assessment in Chinese patients with non-cardiac chest pain...
  34. ncbi request reprint Clinical and endoscopic characteristics of non-Helicobacter pylori, non-NSAID duodenal ulcers: a long-term prospective study
    H H Xia
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Aliment Pharmacol Ther 15:1875-82. 2001
    ..pylori, non-NSAID duodenal ulcers. CONCLUSIONS: Non-H. pylori, non-NSAID duodenal ulcers exhibit certain distinct clinical and endoscopic characteristics. The presence of concomitant diseases is an important predictive factor...
  35. ncbi request reprint An evaluation of the PyloriTek test for the diagnosis of Helicobacter pylori infection in Chinese patients before and after eradication therapy
    W M Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    J Gastroenterol Hepatol 16:976-80. 2001
    ..It enhances clinical decision-making by allowing the clinicians or endoscopists to start therapy on the same day of an endoscopy visit. One biopsy from the antrum is highly reliable for this purpose...
  36. ncbi request reprint Lansoprazole, levofloxacin and amoxicillin triple therapy vs. quadruple therapy as second-line treatment of resistant Helicobacter pylori infection
    W M Wong
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong
    Aliment Pharmacol Ther 23:421-7. 2006
    ..To test the efficacy of levofloxacin-based second-line therapy for resistant Helicobacter pylori infection...
  37. ncbi request reprint Positive association between gastro-oesophageal reflux disease and irritable bowel syndrome in a Chinese population
    T K Cheung
    Department of Medicine, University of Hong Kong, Hong Kong, China
    Aliment Pharmacol Ther 25:1099-104. 2007
    ..Gastro-oesophageal reflux disease and irritable bowel syndrome are common diseases which may be related...
  38. ncbi request reprint Comparison between empirical prokinetics, Helicobacter test-and-treat and empirical endoscopy in primary-care patients presenting with dyspepsia: a one-year study
    Wayne H C Hu
    Department of Medicine, University of Hong Kong, China
    World J Gastroenterol 12:5010-6. 2006
    ..To investigate the optimal strategy to treat dyspeptic patients in primary care...
  39. ncbi request reprint An evaluation of a rapid urine test for the diagnosis of Helicobacter pylori infection in the Chinese population
    W M Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Aliment Pharmacol Ther 16:813-7. 2002
    ..A new rapid urine test was developed to detect anti-Helicobacter pylori antibody in urine using the principle of immunochromatography. The accuracy of this test in the Chinese population remains to be defined...
  40. ncbi request reprint Update on clarithromycin resistance in Helicobacter pylori in Hong Kong and its effect on clarithromycin-based triple therapy
    Q Gu
    Department of Gastroenterology, The First Hospital, Peking University, Beijing, China
    Digestion 73:101-6. 2006
    ..To determine the antibiotic susceptibility of Helicobacter pylori and evaluate the efficacy of a clarithromycin-based triple therapy in relation to antibiotic resistance...
  41. pmc Eradication of Helicobacter pylori infection reverses E-cadherin promoter hypermethylation
    A O O Chan
    Department of Medicine, University of Hong Kong, Hong Kong
    Gut 55:463-8. 2006
    ..Reversing hypermethylation may halt the carcinogenic process. We have previously reported that Helicobacter pylori infection is associated with E-cadherin methylation in chronic gastritis patients...
  42. ncbi request reprint One-week omeprazole, furazolidone and amoxicillin rescue therapy after failure of Helicobacter pylori eradication with standard triple therapies
    W M Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Aliment Pharmacol Ther 16:793-8. 2002
    ..pylori infection...
  43. ncbi request reprint Onset and disappearance of reflux symptoms in a Chinese population: a 1-year follow-up study
    W M Wong
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong
    Aliment Pharmacol Ther 20:803-12. 2004
    ..The natural history of gastro-oesophageal reflux disease in Asian population has not been studied before...
  44. ncbi request reprint A rapid-release 50-mg tablet-based 13C-urea breath test for the diagnosis of Helicobacter pylori infection
    W M Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, China
    Aliment Pharmacol Ther 17:253-7. 2003
    ..Recently, a rapid-release 100-mg 13C-urea tablet with citrate supplement (Diabact UBT) showed excellent performance in a European population...
  45. ncbi request reprint Symptomatic response to lansoprazole predicts abnormal acid reflux in endoscopy-negative patients with non-cardiac chest pain
    H H X Xia
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Aliment Pharmacol Ther 17:369-77. 2003
    ..To determine whether symptomatic response to lansoprazole predicts abnormal acid reflux in endoscopy-negative patients with non-cardiac chest pain...
  46. ncbi request reprint One-week ranitidine bismuth citrate, amoxicillin and metronidazole triple therapy for the treatment of Helicobacter pylori infection in Chinese
    W K Hung
    Department of Surgery, Kwong Wah Hospital, Hong Kong
    Aliment Pharmacol Ther 16:2067-72. 2002
    ....
  47. pmc Aspirin inhibits the growth of Helicobacter pylori and enhances its susceptibility to antimicrobial agents
    W H Wang
    Department of Gastroenterology, First Hospital, Peking University, Beijing, China
    Gut 52:490-5. 2003
    ..The interaction between aspirin and H pylori in vitro is also not clear. We investigated the effect of aspirin on the growth of H pylori and on the susceptibility of H pylori to antimicrobials...
  48. ncbi request reprint Long-term prospective follow-up of endoscopic oesophagitis in southern Chinese--prevalence and spectrum of the disease
    W M Wong
    Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China
    Aliment Pharmacol Ther 16:2037-42. 2002
    ..To study the prevalence, clinical characteristics and long-term outcome of oesophagitis in Chinese patients...
  49. pmc Double blind, randomised, placebo controlled study of four weeks of lansoprazole for the treatment of functional dyspepsia in Chinese patients
    W M Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Gut 51:502-6. 2002
    ..The use of proton pump inhibitors for the treatment of functional dyspepsia is controversial and the role of Helicobacter pylori infection in functional dyspepsia is uncertain...
  50. ncbi request reprint Prevalence, clinical spectrum and health care utilization of gastro-oesophageal reflux disease in a Chinese population: a population-based study
    W M Wong
    Departments of Medicine and Statistics and Actuarial Science, University of Hong Kong, Hong Kong
    Aliment Pharmacol Ther 18:595-604. 2003
    ..Population-based data on gastro-oesophageal reflux disease in Chinese are lacking. The prevalence, clinical spectrum and health care-seeking behaviour of subjects with gastro-oesophageal reflux disease were studied...
  51. ncbi request reprint Anxiety but not depression determines health care-seeking behaviour in Chinese patients with dyspepsia and irritable bowel syndrome: a population-based study
    W H C Hu
    Department of Medicine, University of Hong Kong, China
    Aliment Pharmacol Ther 16:2081-8. 2002
    ..To study the prevalence of dyspepsia and irritable bowel syndrome and the effects of co-existing anxiety and depression on health care utilization by a population survey in Chinese...
  52. ncbi request reprint Normal 24-hour ambulatory proximal and distal gastroesophageal reflux parameters in Chinese
    W H C Hu
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong
    Hong Kong Med J 8:168-71. 2002
    ..To quantify normal proximal and distal oesophageal acid parameters in healthy Chinese...
  53. ncbi request reprint A sensitive guaiac faecal occult blood test is less useful than an immunochemical test for colorectal cancer screening in a Chinese population
    B C Y Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Aliment Pharmacol Ther 18:941-6. 2003
    ..The optimal faecal occult blood test, whether guaiac or immunochemical, for colorectal cancer screening in the Chinese population remains to be defined...
  54. ncbi request reprint Randomized controlled study of rabeprazole, levofloxacin and rifabutin triple therapy vs. quadruple therapy as second-line treatment for Helicobacter pylori infection
    W M Wong
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Aliment Pharmacol Ther 17:553-60. 2003
    ..To test the efficacy of rabeprazole, levofloxacin and rifabutin triple therapy vs. quadruple therapy for the second-line treatment of Helicobacter pylori infection...
  55. ncbi request reprint Double-blind, randomized controlled study to assess the effects of lansoprazole 30 mg and lansoprazole 15 mg on 24-h oesophageal and intragastric pH in Chinese subjects with gastro-oesophageal reflux disease
    W M Wong
    Department of Medicine, University of Hong Kong, Hong Kong SAR, China
    Aliment Pharmacol Ther 19:455-62. 2004
    ..Previous studies have suggested that the acid secretory capacity of the Chinese population is lower than that of the Western population...
  56. ncbi request reprint Trends in the prevalence of peptic ulcer disease and Helicobacter pylori infection in family physician-referred uninvestigated dyspeptic patients in Hong Kong
    B Xia
    Department of Internal Medicine, Research Center of Digestive Diseases of Zhongnan Hospital, Key Laboratory of Allergy and Immune Related Diseases, Wuhan University School of Medicine, China
    Aliment Pharmacol Ther 22:243-9. 2005
    ..Peptic ulcer disease is mainly caused by Helicobacter pylori infection and the use of non-steroidal anti-inflammatory drugs...
  57. pmc Soluble E-cadherin is a valid prognostic marker in gastric carcinoma
    A O Chan
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Gut 48:808-11. 2001
    ..CONCLUSION: Serum soluble E-cadherin is a potential valid prognostic marker for gastric cancer. A high concentration predicts palliative/conservative treatment and T4 invasion...
  58. ncbi request reprint Images of interest. Hepatobiliary and pancreatic: Choledochoduodenal fistula secondary to duodenal ulcer disease
    W M Wong
    Department of Medicine, Queen Mary Hospital, The University of Hong Kong, Hong Kong
    J Gastroenterol Hepatol 19:829. 2004
  59. ncbi request reprint The role of cholecystectomy in reducing recurrent gallstone pancreatitis
    C K Hui
    Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
    Endoscopy 36:206-11. 2004
    ..This is a retrospective study to assess whether cholecystectomy can decrease the incidence of RAP in patients with gallstone-related pancreatitis...
  60. ncbi request reprint A validated symptoms questionnaire (Chinese GERDQ) for the diagnosis of gastro-oesophageal reflux disease in the Chinese population
    W M Wong
    Department of Medicine, University of Hong Kong, Hong Kong S A R, China
    Aliment Pharmacol Ther 17:1407-13. 2003
    ..To develop a validated gastro-oesophageal disease (GERD) symptom questionnaire for the Chinese population...
  61. ncbi request reprint Sequential intravenous/oral antibiotic vs. continuous intravenous antibiotic in the treatment of pyogenic liver abscess
    F H Ng
    Department of Medicine, Ruttonjee Hospital, Hong Kong, ROC
    Aliment Pharmacol Ther 16:1083-90. 2002
    ..In this retrospective analysis, the efficacy of continuous intravenous antibiotic therapy (group I) vs. sequential intravenous/oral antibiotic therapy (group II) was studied in patients with pyogenic liver abscess...
  62. ncbi request reprint Acute cholangitis--predictive factors for emergency ERCP
    C K Hui
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Aliment Pharmacol Ther 15:1633-7. 2001
    ..8% and a specificity of 59.6%. CONCLUSIONS: As patients with severe acute cholangitis show a higher mortality, we recommend that emergency ERCP be performed in patients with one or more of the four prognostic factors...
  63. ncbi request reprint Images of interest. Gastrointestinal: Villous adenoma of the esophagus
    W M Wong
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    J Gastroenterol Hepatol 19:1213. 2004