Ui Soon Khoo

Summary

Affiliation: The University of Hong Kong
Country: China

Publications

  1. ncbi Localization of hRad9 in breast cancer
    Vivian Chan
    University Department of Medicine, Queen Mary Hospital, Hong Kong, China
    BMC Cancer 8:196. 2008
  2. ncbi Role of polymorphisms of the inflammatory response genes and DC-SIGNR in genetic susceptibility to SARS and other infections
    U S Khoo
    Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong
    Hong Kong Med J 14:31-5. 2008
  3. ncbi DC-SIGN and L-SIGN: the SIGNs for infection
    Ui Soon Khoo
    Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, University Pathology Building, Hong Kong, SAR, China
    J Mol Med (Berl) 86:861-74. 2008
  4. ncbi Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection
    Vera S F Chan
    Department of Surgery, Hong Kong Jockey Club Clinical Research Center, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, SAR, China
    Nat Genet 38:38-46. 2006
  5. ncbi CD209 (DC-SIGN) -336A>G promoter polymorphism and severe acute respiratory syndrome in Hong Kong Chinese
    Kelvin Yuen Kwong Chan
    Department of Pathology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China
    Hum Immunol 71:702-7. 2010
  6. ncbi Association of ICAM3 genetic variant with severe acute respiratory syndrome
    Kelvin Y K Chan
    Department of Pathology, University of Hong Kong, Queen Mary Hospital, Pokfulam Rd, Hong Kong
    J Infect Dis 196:271-80. 2007
  7. ncbi Liquid-based cytology and conventional cervical smears: a comparison study in an Asian screening population
    Annie N Y Cheung
    Department of Pathology, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Cancer 99:331-5. 2003
  8. ncbi Single nucleotide polymorphism of pi-class glutathione s-transferase and susceptibility to endometrial carcinoma
    Queeny K Y Chan
    Department of Pathology, The University of Hong Kong, Hong Kong, China
    Clin Cancer Res 11:2981-5. 2005
  9. ncbi Proliferation to apoptosis ratio as a prognostic marker in adenocarcinoma of uterine cervix
    Tsin Wah Leung
    Department of Obstetrics and Gynecology, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Gynecol Oncol 92:866-72. 2004
  10. ncbi SpliceArray profiling of breast cancer reveals a novel variant of NCOR2/SMRT that is associated with tamoxifen resistance and control of ERα transcriptional activity
    Luduo Zhang
    Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
    Cancer Res 73:246-55. 2013

Collaborators

Detail Information

Publications14

  1. ncbi Localization of hRad9 in breast cancer
    Vivian Chan
    University Department of Medicine, Queen Mary Hospital, Hong Kong, China
    BMC Cancer 8:196. 2008
    ..We have previously shown that the mRNA up-regulation correlated with tumor size and local recurrence. Immunohistochemical studies were made to better define the role of hRad9 in breast carcinogenesis...
  2. ncbi Role of polymorphisms of the inflammatory response genes and DC-SIGNR in genetic susceptibility to SARS and other infections
    U S Khoo
    Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong
    Hong Kong Med J 14:31-5. 2008
    ....
  3. ncbi DC-SIGN and L-SIGN: the SIGNs for infection
    Ui Soon Khoo
    Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, University Pathology Building, Hong Kong, SAR, China
    J Mol Med (Berl) 86:861-74. 2008
    ..These findings support the neck region as an excellent candidate acting as a functional target for selective pressures exerted by pathogens...
  4. ncbi Homozygous L-SIGN (CLEC4M) plays a protective role in SARS coronavirus infection
    Vera S F Chan
    Department of Surgery, Hong Kong Jockey Club Clinical Research Center, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, SAR, China
    Nat Genet 38:38-46. 2006
    ..Thus, homozygosity for L-SIGN plays a protective role during SARS infection...
  5. ncbi CD209 (DC-SIGN) -336A>G promoter polymorphism and severe acute respiratory syndrome in Hong Kong Chinese
    Kelvin Yuen Kwong Chan
    Department of Pathology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong SAR, China
    Hum Immunol 71:702-7. 2010
    ..This association is in keeping with the role of CD209 in modulating immune response to viral infection. The relevance of these findings for other infectious diseases and inflammatory conditions would be worth investigating...
  6. ncbi Association of ICAM3 genetic variant with severe acute respiratory syndrome
    Kelvin Y K Chan
    Department of Pathology, University of Hong Kong, Queen Mary Hospital, Pokfulam Rd, Hong Kong
    J Infect Dis 196:271-80. 2007
    ..31 [95% confidence interval {CI}, 1.37-13.56]) and lower total white blood cell counts (P=.022; OR, 0.30 [95% CI, 0.10-0.89]) on admission. These findings support the role of ICAM3 in the immunopathogenesis of SARS...
  7. ncbi Liquid-based cytology and conventional cervical smears: a comparison study in an Asian screening population
    Annie N Y Cheung
    Department of Pathology, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Cancer 99:331-5. 2003
    ....
  8. ncbi Single nucleotide polymorphism of pi-class glutathione s-transferase and susceptibility to endometrial carcinoma
    Queeny K Y Chan
    Department of Pathology, The University of Hong Kong, Hong Kong, China
    Clin Cancer Res 11:2981-5. 2005
    ..In this study, we aimed at determining the association between the GSTP1 polymorphism and the risk of endometrial carcinoma in a Chinese population...
  9. ncbi Proliferation to apoptosis ratio as a prognostic marker in adenocarcinoma of uterine cervix
    Tsin Wah Leung
    Department of Obstetrics and Gynecology, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
    Gynecol Oncol 92:866-72. 2004
    ....
  10. ncbi SpliceArray profiling of breast cancer reveals a novel variant of NCOR2/SMRT that is associated with tamoxifen resistance and control of ERα transcriptional activity
    Luduo Zhang
    Department of Pathology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, China
    Cancer Res 73:246-55. 2013
    ..Our findings highlight a novel splice variant of the ERα corepressor NCOR2 as a candidate biomarker in breast cancer that not only predicts tamoxifen response but may be targeted to overcome tamoxifen resistance...
  11. ncbi Significance of the myxovirus resistance A (MxA) gene -123C>a single-nucleotide polymorphism in suppressed interferon beta induction of severe acute respiratory syndrome coronavirus infection
    Johannes Chi Yun Ching
    Department of Pathology, University of Hong Kong, Princess Margaret Hospital, Hong Kong
    J Infect Dis 201:1899-908. 2010
    ....
  12. ncbi Recurrent BRCA1 and BRCA2 germline mutations in ovarian cancer: a founder mutation of BRCA1 identified in the Chinese population
    Ui Soon Khoo
    Department of Pathology, Queen Mary Hospital, The University of Hong Kong, Hong Kong
    Hum Mutat 19:307-8. 2002
    ....
  13. ncbi Atypical squamous cells of undetermined significance on cervical smears: follow-up study of an Asian screening population
    Annie N Y Cheung
    Department of Pathology, The University of Hong Kong, Hong Kong, China
    Cancer 102:74-80. 2004
    ..The current study reports on the significance of cervical smears identified as atypical squamous cells of undetermined significance (ASCUS) in the largest Asian screening population to date...
  14. ncbi A novel subset of putative stem/progenitor CD34+Oct-4+ cells is the major target for SARS coronavirus in human lung
    Yongxiong Chen
    Department of Surgery, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China
    J Exp Med 204:2529-36. 2007
    ..Infection of these cells may contribute to the loss of lung repair capacity that leads to respiratory failure as clinically observed...