Gavin M Joynt

..To examine the practice and ethical attitudes of intensive care doctors in Hong Kong and to compare findings with those from European studies...

..To examine the demographics, process indicators of adult in-hospital cardiopulmonary arrest resuscitation, and outcomes in a teaching hospital in Hong Kong...

..The effects of intra-abdominal pressure (IAP), followed by restoration of APP with norepinephrine, on renal blood flow were determined...

..To determine the frequency of and potential risk factors for catheter-related deep venous thrombosis (DVT) in critically ill adult patients...

..We assessed the availability, cost, and content of generic short courses designed to teach basic critical care skills to junior physicians or nonspecialist intensive care physicians taking up duties in intensive care units...

..We conclude that in critically ill patients with normal renal function, inadequate plasma concentrations may result following od bolus dosing of ceftriaxone. Drug accumulation may occur in critically ill patients with renal failure...

..We report the case of a 24-year-old man who experienced an acute attack after he had stopped taking his prophylactic medication...

..The objective of this paper was to review the modern published literature to establish a representative consensus view of the incidence, causes, pathophysiology, management and outcome of intra-abdominal hypertension...

..To evaluate factors associated with decisions to refuse ICU admission and to assess the outcome of refused patients...

..To evaluate the incidence of deep venous thrombosis in critically ill, Intensive Care Unit patients of Chinese ethnicity...

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..None of these healthcare workers had antibody to SARS CoV, indicating that subclinical or mild infection attributable to SARS-CoV in adults is rare...

..To describe the extent and temporal pattern of transmission of severe acute respiratory syndrome (SARS) to intensive care unit staff...

..Respiratory assist devices, such as oxygen masks, may enhance the potential to spread infectious aerosols from patients with respiratory infections...

..These data show that adsorption of levofloxacin by PAN haemofilters is concentration dependent and reversible in vitro and suggest that adsorption by haemofilters is unlikely to affect levofloxacin pharmacokinetics significantly in vivo...

..Adsorption is dependent on filter material and is not reversed by a decrease in circulating concentration...

..Close monitoring of peak amikacin levels should be considered for patients receiving CVVH with PAN hemofilters...

..To study the epidemiology of Candida bloodstream infection in the Intensive Care Unit...

..The presence of cysts in one patient who received short-term and one patient who received no mechanical ventilation suggests that severe SARS-induced ARDS may independently result in cyst formation...

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..Pandemic influenza remains a threat to world health and will probably result in an overwhelming number of critically ill patients. Preparations should be made now to meet this threat...

..To determine the period prevalence, demographic characteristics, cost of treatment, and outcomes of patients admitted to the intensive care unit for continuous renal replacement therapy...

..We examined long-term outcome of pulmonary function, exercise capacity and health-related quality of life (HRQoL) in patients with acute respiratory distress syndrome (ARDS) caused by severe acute respiratory syndrome (SARS)...

..Appropriate antibacterial therapy is important to maximize patient survival in sepsis. Acute renal failure complicates optimal antibiotic administration...

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..We conducted a randomized controlled trial to determine if a workshop that uses "illness scripts" could improve students' clinical reasoning skills when making diagnoses of patients portrayed in written scenarios...

..Little is known about the virological and inflammatory responses of severe pandemic 2009 influenza A(H1N1) virus pneumonia during antiviral treatment...

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..Aspartic acid to glycine substitution (D222G) of haemagglutinin subunit (HA1) was associated with adverse outcomes in 2009 pandemic influenza A (H1N1) infections...

..To describe a course designed to help medical undergraduates develop the necessary competencies to recognise and manage acutely ill patients...

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..The authors conducted a randomized controlled trial to determine whether ventilation in ASV results in a shorter time to extubation than pressure-regulated volume-controlled ventilation with automode (PRVCa) after cardiac surgery...

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..Few studies have evaluated the impact of medical training on medical students' attitudes towards end-of-life decisions and none have compared them with an age-matched group of non-medical students...

..To document the outcome and determine prognostic factors for patients with severe acute respiratory syndrome who require admission to an intensive care unit...

..We studied exhaled air and particle dispersion through an oronasal mask attached to a human-patient simulator (HPS) during noninvasive positive-pressure ventilation (NPPV)...

..Withholding therapy rather than withdrawing therapy occurs more frequently than in Western populations...

..Significant adsorption of levofloxacin onto PAN filters occurs...

..To examine the impact of severe acute respiratory syndrome (SARS) on pulmonary function, exercise capacity, and health-related quality of life (HRQoL) among survivors...

..Two cases are presented to illustrate the benefits of using thoracic paravertebral block to control the pain of multiple fractured ribs without compromising the ongoing neurological assessment...

..4; 95% confidence interval, 2.8-31.2). CONCLUSION: After transthoracic oesophagectomy, early extubation is safe and can lead to a shorter stay in the intensive care unit. Epidural analgesia appears to facilitate early extubation...

..5 h. Sixteen (89%) died following MSE and the 2 survivors were highly dependent or remained in a persistent vegetative state, supporting the view that prognosis is poor in this condition...

..These teaching tips introduce clinical learners to decision analysis in a fashion aimed to illustrate principles of clinical reasoning and how patient values can be actively incorporated into complex decision making...

..These widely available HEp-2 cells should be included in conjunction with a molecular method for cell culture followup to detect HMPV, particularly in patients with SARS...

..More comprehensive data are required regarding end-of-life issues in the Asian context, especially in relation to the general population's perception as to the processes involved...

..The overall educational intervention was well received by students and effective in improving students' clinical decision analysis skills under simulated conditions...

..It remains for individual clinicians, patients and their surrogates to decide whether use of high doses of vasopressor is appropriate, given the low probability of survival...

..There is uncertainty about its true precision and this causes difficulty when validating new cardiac output technology. Our aim in this investigation was to determine the current precision error of thermodilution measurements...

..04, 95% CI 1.01-1.07), delay in treatment (OR=3.52, 95%CI 1.01-12.18), SE due to cerebrovascular disease (OR=9.73, 95% CI 1.58-59.96) and CNS infection (OR=30.27, 95% CI 3.14-292.19)...

..60; 95 percent confidence interval, 1.03 to 2.50; P=0.04). CONCLUSIONS: SARS is a serious respiratory illness that led to significant morbidity and mortality in our cohort...

..Increased plasma DNA persists for days after injuries, especially in patients with multiple organ dysfunction syndrome...

..A large randomized, controlled study is required to confirm this impression...

..The aim of this study was to establish an ideal dataset that needs to be reported when presenting pharmacokinetic data for these patients and review current literature for completeness of this dataset...

..CONCLUSION: The use of high dose pulse methylprednisolone during the clinical course of a SARS outbreak was associated with clinical improvement, but randomised controlled trials are needed to ascertain its efficacy in this condition...

..Combining APACHE II score with serum albumin concentrations did not improve the accuracy of outcome prediction over that of APACHE II alone...

..Mortality is around five to ten per cent. Stringent hygiene and quarantine measures are mandatory to prevent the further spread of this threatening disease...