Research Topics
Species | David S-C HuiSummaryAffiliation: The Chinese University of Hong Kong Country: China Publications
| Collaborators
|
Detail Information
Publications
Exhaled air dispersion during coughing with and without wearing a surgical or N95 maskDavid S Hui
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong SAR, The People s Republic of China
PLoS ONE 7:e50845. 2012..We compared the expelled air dispersion distances during coughing from a human patient simulator (HPS) lying at 45° with and without wearing a surgical mask or N95 mask in a negative pressure isolation room...- A prospective cohort study of the long-term effects of CPAP on carotid artery intima-media thickness in obstructive sleep apnea syndromeDavid S Hui
SH Ho Sleep Apnea Management Center, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, New Territories, Hong Kong, China
Respir Res 13:22. 2012..To examine the long-term effect of CPAP on carotid artery intima-media thickness (IMT) in patients with Obstructive sleep apnea syndrome(OSAS)... 
The unmasking of Pneumocystis jiroveci pneumonia during reversal of immunosuppression: case reports and literature reviewAlan K L Wu
Division of Infectious Diseases, Centre of Infection, Queen Mary Hospital, The University of Hong Kong Hong Kong Special Administrative Region, China
BMC Infect Dis 4:57. 2004....
Severe acute respiratory syndrome and coronavirusDavid S C Hui
Division of Respiratory Medicine, Stanley Ho Center for Emerging Infectious Diseases, Prince of Wales Hospital, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
Infect Dis Clin North Am 24:619-38. 2010..Horseshoe bats are implicated in the emergence of novel coronavirus infection in humans. Further studies are needed to examine host genetic markers that may predict clinical outcome...- Impact of severe acute respiratory syndrome (SARS) on pulmonary function, functional capacity and quality of life in a cohort of survivorsD S Hui
Center for Emerging Infectious Diseases, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong
Thorax 60:401-9. 2005..To examine the impact of severe acute respiratory syndrome (SARS) on pulmonary function, exercise capacity, and health-related quality of life (HRQoL) among survivors... 
The 1-year impact of severe acute respiratory syndrome on pulmonary function, exercise capacity, and quality of life in a cohort of survivorsDavid S Hui
Center for Emerging Infectious Diseases, Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, NT, Hong Kong
Chest 128:2247-61. 2005..To examine pulmonary function, exercise capacity, and health-related quality of life (HRQoL) among severe acute respiratory syndrome (SARS) survivors...- An overview on severe acute respiratory syndrome (SARS)D S C Hui
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Monaldi Arch Chest Dis 63:149-57. 2005..Rapid diagnosis, early isolation, and good infection control measures are important in preventing spread of the infection... - Nasal CPAP reduces systemic blood pressure in patients with obstructive sleep apnoea and mild sleepinessD S Hui
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Thorax 61:1083-90. 2006..A randomised controlled study was undertaken to examine the effect of nasal continuous positive airway pressure (CPAP) on 24 hour systemic blood pressure (BP) in patients with obstructive sleep apnoea (OSA)... - Noninvasive positive-pressure ventilation: An experimental model to assess air and particle dispersionDavid S Hui
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, NT, Hong Kong
Chest 130:730-40. 2006..We studied exhaled air and particle dispersion through an oronasal mask attached to a human-patient simulator (HPS) during noninvasive positive-pressure ventilation (NPPV)... - Exhaled air and aerosolized droplet dispersion during application of a jet nebulizerDavid S Hui
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, NT, Hong Kong
Chest 135:648-54. 2009.... - Sleep-disordered breathing and continuous positive airway pressure compliance in a group of commercial bus drivers in Hong KongDavid S C Hui
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
Respirology 11:723-30. 2006..Sleep-disordered breathing may predispose drivers to road traffic accidents. However, CPAP acceptance and compliance among commercial bus drivers is unknown... - Exhaled air dispersion during oxygen delivery via a simple oxygen maskDavid S Hui
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, New Territories, Hong Kong, People s Republic of China
Chest 132:540-6. 2007..We studied the dispersion of exhaled air through a simple oxygen mask applied to a human patient simulator (HPS) during the delivery of different oxygen flow in a room free of air currents... - Exhaled air dispersion and removal is influenced by isolation room size and ventilation settings during oxygen delivery via nasal cannulaDavid S Hui
Stanley Ho Center for Emerging Infectious Diseases, Department Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
Respirology 16:1005-13. 2011..We compared the exhaled air dispersion distances during oxygen delivery via nasal cannula to a human-patient simulator (HPS) in two different isolation rooms... - Review of clinical symptoms and spectrum in humans with influenza A/H5N1 infectionDavid S C Hui
Division of Respiratory Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong
Respirology 13:S10-3. 2008.... - Influenza A/H5N1 infection: other treatment options and issuesDavid S C Hui
Division of Respiratory Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong
Respirology 13:S22-6. 2008..Non-pharmacological measures such as early case isolation, household quarantine, school/workplace closure, good community hygiene and restrictions on travel are useful measures in controlling a pandemic... - Clinical features, pathogenesis and immunobiology of severe acute respiratory syndromeDavid S Hui
Division of Respiratory Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Curr Opin Pulm Med 14:241-7. 2008..A better understanding of these issues may help prevent and control future outbreaks of severe acute respiratory syndrome... - A multicentre surveillance study on the characteristics, bacterial aetiologies and in vitro antibiotic susceptibilities in patients with acute exacerbations of chronic bronchitisDavid S Hui
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
Respirology 16:532-9. 2011..Antimicrobial resistance is a global problem and the prevalence is high in many Asian countries... - Exhaled air dispersion distances during noninvasive ventilation via different Respironics face masksDavid S Hui
David S Hui, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong, People s Republic of China
Chest 136:998-1005. 2009.... - Clinical management of pandemic 2009 influenza A(H1N1) infectionDavid S Hui
Division of Respiratory Medicine, The Chinese University of Hong Kong, 9 F, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, New Territories, Hong Kong
Chest 137:916-25. 2010..Nonpharmacologic measures, such as early case isolation, household quarantine, school/workplace closure, good community hygiene, and restrictions on travel are useful measures in controlling an influenza pandemic at its early phase... - Influenza-like illness in residential care homes: a study of the incidence, aetiological agents, natural history and health resource utilisationD S Hui
Department of Medicine amd Therapeutics, The Chinese University of Hong Kong, 30 32 Ngan Shing St, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Thorax 63:690-7. 2008..A study was undertaken to examine the incidence, underlying aetiology, natural history and associated healthcare resource utilisation related to ILI in the RCHE population... - The effects of nasal continuous positive airway pressure on platelet activation in obstructive sleep apnea syndromeDavid S Hui
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Chest 125:1768-75. 2004..A case-controlled study to assess the effects of nasal continuous positive airway pressure (CPAP) on platelet activation in patients with obstructive sleep apnea (OSAS) syndrome... - Prevalence of sleep-disordered breathing and continuous positive airway pressure compliance: results in chinese patients with first-ever ischemic strokeDavid S C Hui
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Chest 122:852-60. 2002..To assess the prevalence of sleep-disordered breathing (SDB), continuous positive airway pressure (CPAP) acceptance, and CPAP compliance in patients who have experienced ischemic stroke... - SARS: clinical features and diagnosisDavid Shu Cheong Hui
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
Respirology 8:S20-4. 2003.... - Cephalometric assessment of craniofacial morphology in Chinese patients with obstructive sleep apnoeaD S C Hui
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Respir Med 97:640-6. 2003..To compare the differences in craniofacial morphology in Chinese patients with and without obstructive sleep apnoea (OSA)... - Severe acute respiratory syndrome (SARS): epidemiology and clinical featuresD S C Hui
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Postgrad Med J 80:373-81. 2004..Measurement of serum RNA by real time reverse transcriptase-polymerase chain reaction technique has a detection rate of 75%-80% in the first week of the illness... - Prevalence of snoring and sleep-disordered breathing in a group of commercial bus drivers in Hong KongD S C Hui
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories
Intern Med J 32:149-57. 2002..To assess the prevalence of sleep-disordered breathing (SDB) and its associated symptoms in a group of commercial bus drivers in Hong Kong... - Effects of augmented continuous positive airway pressure education and support on compliance and outcome in a Chinese populationD S Hui
Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
Chest 117:1410-6. 2000..To study the effects of augmentation of continuous positive airway pressure (CPAP) education and support on compliance and outcome in patients with obstructive sleep apnea (OSA)... - Determinants of continuous positive airway pressure compliance in a group of Chinese patients with obstructive sleep apneaD S Hui
Department of Medicine and Therapeutics, Centre for Clinical Trials and Epidemiological Research, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Chest 120:170-6. 2001..To assess continuous positive airway pressure (CPAP) compliance and factors associated with CPAP compliance among Chinese patients with obstructive sleep apnea (OSA)... - Prevalence of snoring and sleep-disordered breathing in a student populationD S Hui
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong
Chest 116:1530-6. 1999..We aim to determine the symptoms and prevalence of SDB in a university student population using a questionnaire survey followed by home sleep monitoring... - A one-year prospective study of infectious etiology in patients hospitalized with acute exacerbations of COPD and concomitant pneumoniaFanny W S Ko
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing Street, Shatin, New Territories, Hong Kong
Respir Med 102:1109-16. 2008..This study assessed the infectious etiology of patients hospitalized for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) with concomitant pneumonia... - ACE2 gene polymorphisms do not affect outcome of severe acute respiratory syndromeRossa W K Chiu
The Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Shatin
Clin Chem 50:1683-6. 2004 - Sputum bacteriology in patients with acute exacerbations of COPD in Hong KongFanny W S Ko
Department of Medicine and Therapeutics, Prince of Wales Hospital, Chinese University of Hong Kong, Ngan Shing Street, Shatin, New Territories, Hong Kong
Respir Med 99:454-60. 2005..31/162 episodes, respectively, P=0.02). CONCLUSIONS: H. influenzae was the commonest bacterium isolated in sputum in patients with AECOPD. In areas endemic of tuberculosis, it is advisable to use fluoroquinolones for AECOPD with caution... - Thin-section CT in patients with severe acute respiratory syndrome following hospital discharge: preliminary experienceGregory E Antonio
Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Chinese University of Hong Kong, 30-32 Ngan Shing St, Shatin, Hong Kong SAR
Radiology 228:810-5. 2003..Patients who are older and have more severe disease during treatment are more likely to develop thin-section CT findings of fibrosis... - Severe acute respiratory syndrome: thin-section computed tomography features, temporal changes, and clinicoradiologic correlation during the convalescent periodKa-Tak Wong
Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Hong Kong, China
J Comput Assist Tomogr 28:790-5. 2004.... - Viral etiology of acute exacerbations of COPD in Hong KongFanny W S Ko
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, New Territories, Hong Kong
Chest 132:900-8. 2007..Viral respiratory infections may precipitate acute exacerbations of COPD (AECOPD). However, little is known about viral etiology related to AECOPD in Asia. We aimed to study the viral etiology of AECOPD in Hong Kong... - Imaging of severe acute respiratory syndrome in Hong KongGregory E Antonio
Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Chinese University of Hong Kong, 30-32 Ngan Shing St, Shatin, Hong Kong, Republic of China
AJR Am J Roentgenol 181:11-7. 2003 - Factors associated with early hospital discharge of adult influenza patientsNelson Lee
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
Antivir Ther 12:501-8. 2007..Understanding factors affecting length of hospital stay (LOS) in patients with severe influenza may improve their management... - Value of serum procalcitonin, neopterin, and C-reactive protein in differentiating bacterial from viral etiologies in patients presenting with lower respiratory tract infectionsMargaret Ip
Department of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
Diagn Microbiol Infect Dis 59:131-6. 2007..857, whereas (CRP x PCT)/neopterin was 0.856. Combination of 2 or all 3 of the biomarkers may improve the discriminatory power in delineating bacterial versus viral etiology in LRTI... - Predicting changes in clinical status of young asthmatics: clinical scores or objective parameters?Ting F Leung
Department of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
Pediatr Pulmonol 44:442-9. 2009..203, P = 0.042). In conclusion, C-ACT is better than DSS and objective parameters in reflecting changes in asthma status and predicting asthma exacerbations in young children... - Asthma Control Test correlates well with the treatment decisions made by asthma specialistsFanny W S Ko
Department of Medicine, The Chinese University of Hong Kong, Hong Kong, China
Respirology 14:559-66. 2009.... - Measurement of tumor necrosis factor-alpha, leukotriene B4, and interleukin 8 in the exhaled breath condensate in patients with acute exacerbations of chronic obstructive pulmonary diseaseFanny W S Ko
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong
Int J Chron Obstruct Pulmon Dis 4:79-86. 2009..Assessment of airway inflammation in the clinical course of acute exacerbations of chronic obstructive pulmonary disease (AECOPD) may advance our understanding of the pathogenesis and treatment... - Outdoor air pollution: impact on chronic obstructive pulmonary disease patientsFanny W S Ko
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing Street, Shatin, New Territories, Hong Kong, PRC
Curr Opin Pulm Med 15:150-7. 2009..Recent publications (2007-2008) on the effects of outdoor air pollutants specifically on COPD patients are reviewed in this article... - Acute encephalopathy associated with influenza A infection in adultsNelson Lee
Division of Infectious Diseases, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, 9 F Clinical Sciences Building, Department of Medicine and Therapeutics, Shatin, Hong Kong, People s Republic of China
Emerg Infect Dis 16:139-42. 2010..Patients recovered without sequelae. Hyperactivated cytokine response may play a role in pathogenesis... - Prevalence of allergic rhinitis and its associated morbidity in adults with asthma: a multicentre studyFanny W S Ko
Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
Hong Kong Med J 16:354-61. 2010..To assess the prevalence of allergic rhinitis in adult patients with asthma in Hong Kong, and to compare the morbidity endured by asthma patients with and without allergic rhinitis... - A community model of group therapy for the older patients with chronic obstructive pulmonary disease: a pilot studyJean Woo
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Hong Kong, China
J Eval Clin Pract 12:523-31. 2006..A community-based programme for chronic obstructive pulmonary disease (COPD) patients in group sessions is designed, and the feasibility, acceptability and physical and psychosocial outcomes evaluated... - Human metapneumovirus detection in patients with severe acute respiratory syndromePaul K S Chan
Faculty of Medicine of the Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
Emerg Infect Dis 9:1058-63. 2003..These widely available HEp-2 cells should be included in conjunction with a molecular method for cell culture followup to detect HMPV, particularly in patients with SARS... - 12-year change in prevalence of respiratory symptoms in elderly Chinese living in Hong KongFanny W S Ko
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing Street, Shatin, New Territories, Hong Kong
Respir Med 100:1598-607. 2006..7% in 1991 and 7.7% in 2003). The prevalence of respiratory symptoms has increased over the past 12 years and this may be related to environmental factors especially increasing air pollution in Hong Kong... - Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control studyK C Allen Chan
The Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Prince of Wales Hospital, Hong Kong
BMC Infect Dis 5:26. 2005..Thus, we have investigated the association between ACE insertion/deletion (I/D) polymorphism and the progression to ARDS or requirement of intensive care in SARS patients... - Laboratory diagnosis of SARSPaul K S Chan
Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China
Emerg Infect Dis 10:825-31. 2004..Positive virologic test results in patient groups were associated with mechanical ventilation or death (p < 0.001), suggesting a correlation between viral load and disease severity... - Early results of endoscopic lung volume reduction for emphysemaAnthony P C Yim
Division of Cardiothoracic Surgery, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, China
J Thorac Cardiovasc Surg 127:1564-73. 2004..We determined the feasibility, safety, and short-term efficacy of bronchoscopic placement of a one-way endobronchial valve in selected bronchopulmonary segments as an alternative to surgical lung volume reduction... - Exhaled breath condensate levels of 8-isoprostane, growth related oncogene alpha and monocyte chemoattractant protein-1 in patients with chronic obstructive pulmonary diseaseFanny W S Ko
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Respir Med 100:630-8. 2006..8-isoprostane level, but not GROalpha and MCP-1, in EBC was increased in COPD patients with poorer lung function. This suggests an increased oxidative stress in the airway in patients with more severe COPD... - A 1-year prospective study of the infectious etiology in patients hospitalized with acute exacerbations of COPDFanny W S Ko
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing St, Shatin, New Territories, Hong Kong, Peoples Republic of China
Chest 131:44-52. 2007..Infection is a major cause of acute exacerbations of COPD (AECOPDs). We aimed to study the infectious etiology related to AECOPD... - Long-term outcome of acute respiratory distress syndrome caused by severe acute respiratory syndrome (SARS): an observational studyThomas St Li
Department of Anaesthesia and Intensive Care, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong
Crit Care Resusc 8:302-8. 2006..We examined long-term outcome of pulmonary function, exercise capacity and health-related quality of life (HRQoL) in patients with acute respiratory distress syndrome (ARDS) caused by severe acute respiratory syndrome (SARS)... - Temporal relationship between air pollutants and hospital admissions for chronic obstructive pulmonary disease in Hong KongFanny W S Ko
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing Street, Shatin, New Territories, Hong Kong
Thorax 62:780-5. 2007..To assess any relationship between the levels of ambient air pollutants and hospital admissions for chronic obstructive pulmonary disease (COPD) in Hong Kong... - Are exhaled breath condensates useful in monitoring asthma?Fanny W S Ko
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing Street, Shatin, New Territories, Hong Kong
Curr Allergy Asthma Rep 7:65-71. 2007..More studies are needed before this technique can be recommended for clinical use... - SARS: clinical presentation, transmission, pathogenesis and treatment optionsPaul K S Chan
Department of Microbiology, Faculty of Medicine, The Chinese University of Hong Kong, Hong Kong Special Administrative Region, People s Republic of China
Clin Sci (Lond) 110:193-204. 2006..Although SARS led to more than 700 deaths worldwide, the lessons learnt have prepared healthcare systems worldwide to face future emerging and re-emerging infections... - Allele-specific conventional reverse-transcription polymerase chain reaction as a screening assay for discriminating influenza a H1N1 (H275Y) oseltamivir-resistant and wild-type virusesKarry L K Ngai
Faculty of Medicine, Department of Microbiology, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong Special Administration Region, China
J Med Virol 82:1295-8. 2010..Further improvement in performance is expected when applied to cell culture isolates with a higher viral titer. These allele-specific cRT-PCR assays can be a simple, low-cost option for large-scale screening of influenza isolates... - Validation of Embletta portable diagnostic system for identifying patients with suspected obstructive sleep apnoea syndrome (OSAS)Susanna S S Ng
Division of Respiratory Medicine, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, HK, China
Respirology 15:336-42. 2010..The simple device may be useful for screening and diagnostic purpose when access to PSG is limited... - Advancements in the battle against severe acute respiratory syndromeDavid S C Hui
Department of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Expert Opin Pharmacother 5:1687-93. 2004..This paper provides a review of the epidemiology, clinical features and possible treatment strategies of SARS... - Role of 'atypical pathogens' among adult hospitalized patients with community-acquired pneumoniaGrace Lui
Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong
Respirology 14:1098-105. 2009..This study examined the role of these 'atypical pathogens' (AP) among adult hospitalized patients with CAP... - Increased expression of plasma and CD4+ T lymphocyte costimulatory molecule CD26 in adult patients with allergic asthmaSamantha W M Lun
Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
J Clin Immunol 27:430-7. 2007..05). In conclusion, the aberrant expression of CD26 may contribute to the inflammatory process and Th2 predominance in the immunopathogenesis of allergic asthma... - Viral loads and duration of viral shedding in adult patients hospitalized with influenzaNelson Lee
Department of Medicine and Therapeutics, Stanley Ho Centre for Emerging Infectious Diseases, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
J Infect Dis 200:492-500. 2009..The goal of this study was to characterize viral loads and factors affecting viral clearance in persons with severe influenza... - Steroid-induced osteonecrosis in severe acute respiratory syndrome: a retrospective analysis of biochemical markers of bone metabolism and corticosteroid therapyMichael H M Chan
Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
Pathology 38:229-35. 2006..The Day 28-44 increase in the serum CTx coincided with the timing of corticosteroid use. The Day >51 increase in serum OC and BALP coincided with the timing of corticosteroid withdrawal... - Chest radiograph scores as potential prognostic indicators in severe acute respiratory syndrome (SARS)Gregory E Antonio
Department of Diagnostic Radiology and Organ Imaging, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China
AJR Am J Roentgenol 184:734-41. 2005..73 per 5% of AO% (p < 0.0001) or 2.93 per lung zone opacified (p < 0.0001). CONCLUSION: Chest radiographic scores (percentage of lung or the number of zones opacified) by day 7 could be used as fatal prognostic indicators... - Airflow and droplet spreading around oxygen masks: a simulation model for infection control researchMargaret Ip
Centre for Emerging Infectious Diseases, School of Public Health, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong SAR, China
Am J Infect Control 35:684-9. 2007..Respiratory assist devices, such as oxygen masks, may enhance the potential to spread infectious aerosols from patients with respiratory infections... - Development and comparison of molecular assays for the rapid detection of the pandemic influenza A (H1N1) 2009 virusWai Yip Lam
Faculty of Medicine, Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, People s Republic of China
J Med Virol 82:675-83. 2010..The newly developed cRT-PCR assay targeting the HA gene allows rapid, specific, and sensitive screening of this novel agent, which can serve as an alternative for laboratories where a real-time PCR machine is not available... - Thin-section CT of severe acute respiratory syndrome: evaluation of 73 patients exposed to or with the diseaseK T Wong
Department of Diagnostic Radiology, Prince of Wales Hospital, Chinese University of Hong Kong, 30 32 Ngan Shing St, Shatin, Hong Kong SAR
Radiology 228:395-400. 2003..To retrospectively analyze the thin-section computed tomographic (CT) features in patients with severe acute respiratory syndrome (SARS) at the authors' institution... - Expression and functional analysis of toll-like receptors of peripheral blood cells in asthmatic patients: implication for immunopathological mechanism in asthmaSamantha W M Lun
Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
J Clin Immunol 29:330-42. 2009..05). Therefore, the decreased activation of TLR4 and TLR5 in asthmatic patients might contribute to the immunopathological mechanisms of asthma by reducing the release of Th1 and anti-inflammatory cytokines... - Prevalence of sleep disturbances in Chinese patients with end stage renal failure on maintenance hemodialysisDavid S C Hui
Department of Medicine and Therapeutics, Division of Respiratory Medicine, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
Med Sci Monit 8:CR331-6. 2002..Sleep disorders, such as daytime sleepiness, insomnia, restless legs syndrome (RLS) and obstructive sleep apnea syndrome (OSAS) have been reported as prevalent among patients with end stage renal failure(ESRF)... - Aberrant expression of CC and CXC chemokines and their receptors in patients with asthmaSamantha W M Lun
Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong, China
J Clin Immunol 26:145-52. 2006..05). In conclusion, plasma RANTES may be a surrogate marker for asthma and the diminished Th1 related CXC chemokine production may contribute to Th2 predominance in asthma... - Severe obstructive sleep apnea is associated with left ventricular diastolic dysfunctionJeffrey W H Fung
Division of Cardiology, Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
Chest 121:422-9. 2002..005). CONCLUSION: Diastolic dysfunction with ARP was common in patients with OSA. More severe sleep apnea was associated with a higher degree of left ventricular diastolic dysfunction in this study... - The impact of severe acute respiratory syndrome on the physical profile and quality of lifeHerman Mun-Cheung Lau
Physiotherapy Department, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, P.R. China
Arch Phys Med Rehabil 86:1134-40. 2005..05). CONCLUSIONS: SARS survivors had deficits in cardiorespiratory and musculoskeletal performance, and their HRQOL appeared to be significantly impaired... - A randomised controlled trial of the effectiveness of an exercise training program in patients recovering from severe acute respiratory syndromeHerman Mun Cheung Lau
Department of Physiotherapy, The Prince of Wales Hospital, Shatin, Hong Kong, China
Aust J Physiother 51:213-9. 2005..However, health-related quality of life was not affected by physical training... - Early enhanced expression of interferon-inducible protein-10 (CXCL-10) and other chemokines predicts adverse outcome in severe acute respiratory syndromeNelson Leung Sang Tang
Department of Chemical Pathology, Faculty of Medicine, The Chinese University of Hong Kong, Shatin
Clin Chem 51:2333-40. 2005..Previous studies on chemokines have included only small numbers of patients, and the utility of plasma chemokines as prognostic indicators is unclear... - Lack of support for an association between CLEC4M homozygosity and protection against SARS coronavirus infectionNelson Leung-Sang Tang
Nat Genet 39:691-2; author reply 694-6. 2007