Ki Wai Chik

Summary

Affiliation: The Chinese University of Hong Kong
Country: China

Publications

  1. ncbi request reprint Elevated serum interleukin-15 level in acute graft-versus-host disease after hematopoietic cell transplantation
    Ki Wai Chik
    Department of Pediatrics, The Chinese University of Hong Kong, Peoples Republic of China
    J Pediatr Hematol Oncol 25:960-4. 2003
  2. ncbi request reprint Oseltamivir prophylaxis during the influenza season in a paediatric cancer centre: prospective observational study
    K W Chik
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Hong Kong Med J 10:103-6. 2004
  3. ncbi request reprint Case report: human herpesvirus 7 associated fatal encephalitis in a peripheral blood stem cell transplant recipient
    Paul K S Chan
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    J Med Virol 66:493-6. 2002
  4. ncbi request reprint Arsenic trioxide mediates intrinsic and extrinsic pathways of apoptosis and cell cycle arrest in acute megakaryocytic leukemia
    Hubert Kin Bong Lam
    Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, P R China
    Int J Oncol 27:537-45. 2005
  5. ncbi request reprint Neurocutaneous melanomatosis with a rapidly deteriorating course
    Winnie C W Chu
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing Street, Shatin, Hong Kong, China
    AJNR Am J Neuroradiol 24:287-90. 2003
  6. ncbi request reprint Autoimmune hypothyroidism after unrelated haematopoietic stem cell transplantation in children
    Vincent Lee
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong
    J Pediatr Hematol Oncol 28:293-5. 2006
  7. ncbi request reprint Growth and endocrine function following bone marrow transplantation for thalassemia major
    Chi Kong Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, China
    Pediatr Hematol Oncol 21:411-9. 2004
  8. ncbi request reprint Detection of micrometastasis of neuroblastoma to bone marrow and tumor dissemination to hematopoietic autografts using flow cytometry and reverse transcriptase-polymerase chain reaction
    Kam Sze Tsang
    Division of Hematology Blood and Marrow Transplantation, Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, China
    Cancer 97:2887-97. 2003
  9. ncbi request reprint Enlargement of hepatoduodenal ligament lymph nodes in beta thalassemia children receiving multiple transfusions: a common observation
    Winnie C W Chu
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Haematologica 87:882-4. 2002
  10. ncbi request reprint Genetic variation of glycoproteins B and H of human herpesvirus 7 in Hong Kong
    Paul K S Chan
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    J Med Virol 71:429-33. 2003

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Elevated serum interleukin-15 level in acute graft-versus-host disease after hematopoietic cell transplantation
    Ki Wai Chik
    Department of Pediatrics, The Chinese University of Hong Kong, Peoples Republic of China
    J Pediatr Hematol Oncol 25:960-4. 2003
    ..To correlate serum cytokine levels and the development of acute graft-versus-host disease (GVHD), the authors conducted a prospective study on serial measurements of interferon (IFN)-gamma and interleukin (IL)-10, IL-12 and IL-15...
  2. ncbi request reprint Oseltamivir prophylaxis during the influenza season in a paediatric cancer centre: prospective observational study
    K W Chik
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Hong Kong Med J 10:103-6. 2004
    ..To determine the role of oseltamivir prophylaxis for immunocompromised patients...
  3. ncbi request reprint Case report: human herpesvirus 7 associated fatal encephalitis in a peripheral blood stem cell transplant recipient
    Paul K S Chan
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    J Med Virol 66:493-6. 2002
    ..All microbiological investigations were negative, except for the presence of HHV-7 DNA in cerebrospinal fluid and brain stem tissue samples...
  4. ncbi request reprint Arsenic trioxide mediates intrinsic and extrinsic pathways of apoptosis and cell cycle arrest in acute megakaryocytic leukemia
    Hubert Kin Bong Lam
    Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong, P R China
    Int J Oncol 27:537-45. 2005
    ..The multiple-signaling mechanism of ATO warrants it a potential agent to incorporate in the treatment regimen of AMKL...
  5. ncbi request reprint Neurocutaneous melanomatosis with a rapidly deteriorating course
    Winnie C W Chu
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, 30 32 Ngan Shing Street, Shatin, Hong Kong, China
    AJNR Am J Neuroradiol 24:287-90. 2003
    ..We present serial MR imaging findings in the brain and spine of a child with congenital giant hairy nevi who developed progressive leptomeningeal melanomatosis and whose neurologic condition rapidly deteriorated...
  6. ncbi request reprint Autoimmune hypothyroidism after unrelated haematopoietic stem cell transplantation in children
    Vincent Lee
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong
    J Pediatr Hematol Oncol 28:293-5. 2006
    ..The causes of post-transplantation autoimmune hypothyroidism are probably multiple. In these two patients, the presence of chronic graft-versus-host disease may be the most significant contributing factor...
  7. ncbi request reprint Growth and endocrine function following bone marrow transplantation for thalassemia major
    Chi Kong Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, China
    Pediatr Hematol Oncol 21:411-9. 2004
    ..One patient developed diabetes mellitus and one had growth hormone deficiency after BMT. In conclusion, improvement of growth after BMT in TM was common. Gonadal failure is universal in girls, and boys were less affected...
  8. ncbi request reprint Detection of micrometastasis of neuroblastoma to bone marrow and tumor dissemination to hematopoietic autografts using flow cytometry and reverse transcriptase-polymerase chain reaction
    Kam Sze Tsang
    Division of Hematology Blood and Marrow Transplantation, Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, China
    Cancer 97:2887-97. 2003
    ..The identification of neuroblastoma metastases to bone marrow (BM) is requisite in staging disease for risk-adopted therapy. However, micrometastases were not elucidated fully...
  9. ncbi request reprint Enlargement of hepatoduodenal ligament lymph nodes in beta thalassemia children receiving multiple transfusions: a common observation
    Winnie C W Chu
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Haematologica 87:882-4. 2002
  10. ncbi request reprint Genetic variation of glycoproteins B and H of human herpesvirus 7 in Hong Kong
    Paul K S Chan
    Department of Microbiology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR, China
    J Med Virol 71:429-33. 2003
    ..4%) Hong Kong isolates were of the gH allele group B, and all others were of the gH allele group C. These data indicate the possibility of using gB or gH alleles as markers for studying world-wide population movements and genetics...
  11. ncbi request reprint Identification of TPO receptors on central nervous system-a preliminary report
    Mo Yang
    Department of Paediatrics, The Chinese University of Hong Kong, Hong Kong
    Zhongguo Shi Yan Xue Ye Xue Za Zhi 12:494-7. 2004
    ..In conclusion, the first evidence showed the expression of TPO receptor c-mpl in central nervous system. Moreover, the effect of TPO on neural cell proliferation and anti-apoptosis was also demonstrated on in vitro neural cells...
  12. ncbi request reprint Clonal evolution of 8p11 stem cell syndrome in a 14-year-old Chinese boy: a review of literature of t(8;13) associated myeloproliferative diseases
    Wai Shan Wong
    Department of Anatomical and Cellular Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong SAR, China
    Leuk Res 31:235-8. 2007
    ..Also differential clonal TcRgamma gene rearrangements in the BM and LN samples were observed. These findings provide novel insights into the genetic pathogenesis...
  13. ncbi request reprint Immunogenicity of a two-dose regime of varicella vaccine in children with cancers
    Ting Fan Leung
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, China
    Eur J Haematol 72:353-7. 2004
    ..Live-attenuated varicella vaccine is effective and safe in immunocompetent children. In this study, we assess the immunogenicity and adverse events following varicella vaccination in immunosuppressed cancer children...
  14. doi request reprint Humoral immune response after post-chemotherapy booster diphtheria-tetanus-pertussis vaccine in pediatric oncology patients
    Frankie Wai Tsoi Cheng
    Department of Pediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong Hong Kong
    Pediatr Blood Cancer 52:248-53. 2009
    ..In this randomized controlled study, we studied the effect of immune responses to diphtheria-tetanus-pertussis (DTP) booster vaccination in children 6 months after completing chemotherapy...
  15. ncbi request reprint Second transplant for a thalassemia patient after graft rejection: with immunosuppression and allogeneic peripheral blood stem cell
    Chi Kong Li
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong
    Pediatr Hematol Oncol 19:267-71. 2002
    ..There were no severe treatment-related complications or acute or chronic graft versus host disease after second transplant. The patient remained transfusion independent at 26 months after second transplant...
  16. ncbi request reprint Thrombospondin-1 induces apoptosis in primary leukemia and cell lines mediated by CD36 and Caspase-3
    Karen Li
    Department of Paediatrics, Prince of Wales Hospital, Shatin, N T, Hong Kong
    Int J Mol Med 12:995-1001. 2003
    ..Our data provided strong evidence that TSP-1 exerted direct apoptotic effects on leukemia cells and could be developed as an adjunct to conventional therapy, particularly for leukemia cells that express CD36 or other TSP-1 receptors...
  17. ncbi request reprint White matter and cerebral metabolite changes in children undergoing treatment for acute lymphoblastic leukemia: longitudinal study with MR imaging and 1H MR spectroscopy
    Winnie C W Chu
    Department of Diagnostic Radiology and Organ Imaging, Medical Physics Div, Chinese Univ of Hong Kong, Prince of Wales Hosp, 30 32 Ngan Shing St, Shatin, Hong Kong SAR, China
    Radiology 229:659-69. 2003
    ..To assess the development of white matter and cerebral metabolite changes during and after treatment in children with acute lymphoblastic leukemia...
  18. ncbi request reprint Patterns of bone diseases in transfusion-dependent homozygous thalassaemia major: predominance of osteoporosis and desferrioxamine-induced bone dysplasia
    Yu Leung Chan
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Pediatr Radiol 32:492-7. 2002
    ..To study the radiographic skeletal changes in transfusion-dependent homozygous beta-thalassaemia...
  19. ncbi request reprint Liver volume in thalassaemia major: relationship with body weight, serum ferritin, and liver function
    Yu Leung Chan
    Department of Diagnostic Radiology and Organ Imaging, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
    Pediatr Radiol 35:165-8. 2005
    ..It is not known whether body weight alone can adjust for the volume of liver in the calculation of the chelating dose in beta-thalassaemia major patients, who frequently have iron overload and hepatitis...
  20. ncbi request reprint Periorbital alveolar soft part sarcoma with radiologic features mimicking haemangioma
    Winnie C W Chu
    Department of Diagnostic Radiology and Organ Imaging, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Med Pediatr Oncol 41:145-6. 2003
  21. ncbi request reprint Predominant hematopoietic origin of cell-free DNA in plasma and serum after sex-mismatched bone marrow transplantation
    Yanni Y N Lui
    Department of Chemical Pathology, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong SAR
    Clin Chem 48:421-7. 2002
    ..We used a sex-mismatched bone marrow transplantation model to study the relative contribution of hematopoietic and nonhematopoietic cells to circulating DNA...
  22. ncbi request reprint Critical airway obstruction, superior vena cava syndrome, and spontaneous cardiac arrest in a child with acute leukemia
    Kam Lun Ellis Hon
    Department of Paediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    Pediatr Emerg Care 21:844-6. 2005
    ..This report serves to alert clinicians of the oncological emergency of "superior mediastinal syndrome" causing airway and superior vena cava obstruction leading to death in this potentially curable disease...
  23. pmc A malignant itch
    Kam Lun Ellis Hon
    Department of Pediatrics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong
    J Natl Med Assoc 98:1992-4. 2006
    ..This report serves to alert clinicians of the gold paradigm that in a patient with an unexplained generalized itch, lymphoma and other malignancies must be considered...
  24. ncbi request reprint A randomized controlled study evaluating the safety and efficacy of deferiprone treatment in thalassemia major patients from Hong Kong
    Shau Yin Ha
    Department of Pediatrics and Adolescent Medicine, The University of Hong Kong, Queen Mary Hospital, PR China
    Hemoglobin 30:263-74. 2006
    ..We conclude that the short-term use of L1, with or without DFO, was safe and efficacious in our Chinese patient cohort. The long-term efficacy of reducing iron overload by treatment regimens including L1 requires further study...