Gregory Cheng

Summary

Affiliation: The Chinese University of Hong Kong
Country: China

Publications

  1. doi Eltrombopag for the treatment of immune thrombocytopenia
    Gregory Cheng
    Dr Stanley Ho Medical Development Foundation, 9 F ICBC Tower, Macau Landmark, 555 Avenida da Amizade, Macau, China
    Expert Rev Hematol 4:261-9. 2011
  2. ncbi Factors affecting the maintenance stable warfarin dosage in Hong Kong Chinese patients
    Vivian W Y Lee
    School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N T, Hong Kong
    J Thromb Thrombolysis 20:33-8. 2005
  3. pmc Incidence of Deep Vein Thrombosis in Hospitalized Chinese Medical Patients and the Impact of DVT Prophylaxis
    Gregory Cheng
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong
    Thrombosis 2011:629383. 2011
  4. doi Eltrombopag for management of chronic immune thrombocytopenia (RAISE): a 6-month, randomised, phase 3 study
    Gregory Cheng
    Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China
    Lancet 377:393-402. 2011
  5. ncbi Use of convalescent plasma therapy in SARS patients in Hong Kong
    Y Cheng
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing Street, Shatin, Hong Kong
    Eur J Clin Microbiol Infect Dis 24:44-6. 2005
  6. doi Warfarin dosing algorithm using clinical, demographic and pharmacogenetic data from Chinese patients
    Joyce H S You
    School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong
    J Thromb Thrombolysis 31:113-8. 2011
  7. ncbi Association of Vitamin K epoxide reductase complex 1 (VKORC1) variants with warfarin dose in a Hong Kong Chinese patient population
    David L Veenstra
    School of Pharmacy, The Chinese University of Hong Kong, Hong Kong
    Pharmacogenet Genomics 15:687-91. 2005
  8. ncbi The potential clinical and economic outcomes of pharmacogenetics-oriented management of warfarin therapy - a decision analysis
    Joyce H S You
    Centre for Pharmacoeconomics Research, School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong Shatin, N T, Hong Kong, China
    Thromb Haemost 92:590-7. 2004
  9. pmc Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis
    Raymond S M Wong
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China
    BMJ 326:1358-62. 2003
  10. doi Simultaneous measurement of S-warfarin, R-warfarin, S-7-hydroxywarfarin and R-7-hydroxywarfarin in human plasma by liquid chromatography-tandem mass spectrometry
    Zhong Zuo
    School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, SAR
    J Pharm Biomed Anal 52:305-10. 2010

Collaborators

Detail Information

Publications18

  1. doi Eltrombopag for the treatment of immune thrombocytopenia
    Gregory Cheng
    Dr Stanley Ho Medical Development Foundation, 9 F ICBC Tower, Macau Landmark, 555 Avenida da Amizade, Macau, China
    Expert Rev Hematol 4:261-9. 2011
    ....
  2. ncbi Factors affecting the maintenance stable warfarin dosage in Hong Kong Chinese patients
    Vivian W Y Lee
    School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N T, Hong Kong
    J Thromb Thrombolysis 20:33-8. 2005
    ..Multiple factors can affect the anticoagulation effect of warfarin. The objective of this study was to determine the relationship between different clinical factors and outcomes of warfarin therapy in Hong Kong Chinese patients...
  3. pmc Incidence of Deep Vein Thrombosis in Hospitalized Chinese Medical Patients and the Impact of DVT Prophylaxis
    Gregory Cheng
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, Hong Kong
    Thrombosis 2011:629383. 2011
    ..8%, 2%, and 1.7% for the year 2005, 2006, and 2007, respectively. The incidence was 1.1% for 2008 (P < .001). Conclusion. Proximal DVT was substantial in Chinese medical patients, and DVT prophylaxis might reduce such risk...
  4. doi Eltrombopag for management of chronic immune thrombocytopenia (RAISE): a 6-month, randomised, phase 3 study
    Gregory Cheng
    Chinese University of Hong Kong, Shatin, NT, Hong Kong SAR, China
    Lancet 377:393-402. 2011
    ..We aimed to compare the response to once daily eltrombopag versus placebo in patients with chronic immune thrombocytopenia during a 6-month period...
  5. ncbi Use of convalescent plasma therapy in SARS patients in Hong Kong
    Y Cheng
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Ngan Shing Street, Shatin, Hong Kong
    Eur J Clin Microbiol Infect Dis 24:44-6. 2005
    ..3% vs 15.6%; P<0.001) and among those who were PCR positive and seronegative for coronavirus at the time of plasma infusion (66.7% vs 20%; P=0.001)...
  6. doi Warfarin dosing algorithm using clinical, demographic and pharmacogenetic data from Chinese patients
    Joyce H S You
    School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, NT, Hong Kong
    J Thromb Thrombolysis 31:113-8. 2011
    ..In conclusion, a genotype-guided dosing algorithm for warfarin therapy was developed for Chinese patients to explain 68% of dosage variation. The predicted doses differed from the actual doses by no more than 20% in 50% of patients...
  7. ncbi Association of Vitamin K epoxide reductase complex 1 (VKORC1) variants with warfarin dose in a Hong Kong Chinese patient population
    David L Veenstra
    School of Pharmacy, The Chinese University of Hong Kong, Hong Kong
    Pharmacogenet Genomics 15:687-91. 2005
    ..To evaluate the association of VKORC1 genetic variants with warfarin dose requirements in a Hong Kong Chinese patient population...
  8. ncbi The potential clinical and economic outcomes of pharmacogenetics-oriented management of warfarin therapy - a decision analysis
    Joyce H S You
    Centre for Pharmacoeconomics Research, School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong Shatin, N T, Hong Kong, China
    Thromb Haemost 92:590-7. 2004
    ..The cost-effectiveness of this treatment scheme depends on the relative cost and effectiveness of a pharmacogenetics-oriented intensified anticoagulation service comparing to the standard AC care...
  9. pmc Haematological manifestations in patients with severe acute respiratory syndrome: retrospective analysis
    Raymond S M Wong
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong Special Administrative Region, China
    BMJ 326:1358-62. 2003
    ..To evaluate the haematological findings of patients with severe acute respiratory syndrome (SARS)...
  10. doi Simultaneous measurement of S-warfarin, R-warfarin, S-7-hydroxywarfarin and R-7-hydroxywarfarin in human plasma by liquid chromatography-tandem mass spectrometry
    Zhong Zuo
    School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, SAR
    J Pharm Biomed Anal 52:305-10. 2010
    ..The method was successfully applied to analyze the steady state plasma concentrations of the four analytes in 30 patients...
  11. ncbi Cost-effectiveness of two models of management for patients on chronic warfarin therapy--a Markov model analysis
    Joyce H S You
    Centre for Pharmacoeconomics Research, School of Pharmacy, Faculty of Medicine, The Chinese University of Hong Kong, Shatin, N T, Hong Kong
    Thromb Haemost 90:1106-11. 2003
    ..In conclusion, the coordinated care provided by an anticoagulation clinic appears to be more cost-effective than routine medical care in the management of warfarin therapy from the perspective of public health organization in Hong Kong...
  12. ncbi Initial treatment of immune thrombocytopenic purpura with high-dose dexamethasone
    Yunfeng Cheng
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Shatin NT, Hong Kong
    N Engl J Med 349:831-6. 2003
    ..We assessed the effectiveness of high-dose dexamethasone as initial treatment in a series of consecutive adults with immune thrombocytopenic purpura...
  13. ncbi Successful treatment of pure red cell aplasia associated with systemic lupus erythematosus with oral danazol and steroid
    Alice Y K Chan
    Rheumatology Unit, Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Rheumatol Int 25:388-90. 2005
    ..Oral danazol 200 mg twice per day was started together with low-dose prednisolone therapy. There was no further recurrence of anemia 1 month after this combined therapy...
  14. pmc A mathematical model for fresh frozen plasma transfusion strategies during major trauma resuscitation with ongoing hemorrhage
    Anthony M H Ho
    Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong SAR, PRC
    Can J Surg 48:470-8. 2005
    ..Meanwhile, coagulopathy remains a common occurrence during major trauma resuscitation and hemorrhage remains a major cause of traumatic deaths, suggesting that current coagulation factor replacement practices may be inadequate...
  15. ncbi Cross-reactivity of antibody against SARS-coronavirus nucleocapsid protein with IL-11
    Man Cheng
    Department of Biochemistry, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong, China
    Biochem Biophys Res Commun 338:1654-60. 2005
    ..In a neutralization assay, IL-11-induced STAT 3 phosphorylation in rat intestinal epithelial IEC-18 cells was completely suppressed by the anti-N scFv clone L9N01...
  16. ncbi Relationship between patients' warfarin knowledge and anticoagulation control
    Elaine Othilia Y L Tang
    School of Pharmacy, The Chinese University of Hong Kong, Hong Kong
    Ann Pharmacother 37:34-9. 2003
    ..To evaluate patients' knowledge of warfarin and its relationship to anticoagulation control...
  17. ncbi The effects of nasal continuous positive airway pressure on platelet activation in obstructive sleep apnea syndrome
    David S Hui
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Chest 125:1768-75. 2004
    ..A case-controlled study to assess the effects of nasal continuous positive airway pressure (CPAP) on platelet activation in patients with obstructive sleep apnea (OSAS) syndrome...
  18. ncbi Use of herbal medicines by patients receiving warfarin
    Raymond S M Wong
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Drug Saf 26:585-8. 2003
    ..Patients receiving warfarin therapy are discouraged from taking herbal medicines. Whether patients adhere to this advice and, if they do not, the types of products they use, are not known...