Eric Yu Hai Chen

Summary

Affiliation: The University of Hong Kong
Country: China

Publications

  1. ncbi request reprint Prevalence and course of schizophrenia in a Chinese rural area
    Mao Sheng Ran
    Institute of Mental Health, West China Hospital, West China Medical School of Sichuan University, Chengdu
    Aust N Z J Psychiatry 37:452-7. 2003
  2. ncbi request reprint A prospective 3-year longitudinal study of cognitive predictors of relapse in first-episode schizophrenic patients
    Eric Yu Hai Chen
    Department of Psychiatry, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Schizophr Res 77:99-104. 2005
  3. doi request reprint HT1001, a proprietary North American ginseng extract, improves working memory in schizophrenia: a double-blind, placebo-controlled study
    Eric Y H Chen
    Department of Psychiatry, Queen Mary Hospital, University of Hong Kong, Hong Kong, S A R, China
    Phytother Res 26:1166-72. 2012
  4. pmc Suicide among adults aged 30-49: a psychological autopsy study in Hong Kong
    Paul W C Wong
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, Pokfulam, Hong Kong SAR, PR China
    BMC Public Health 8:147. 2008
  5. ncbi request reprint Stroop interference and facilitation effects in first-episode schizophrenic patients
    E Y Chen
    Department of Psychiatry, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, Hong Kong
    Schizophr Res 48:29-44. 2001
  6. ncbi request reprint Self-administered instrument to measure the patient's experience of recovery after first-episode psychosis: development and validation of the Psychosis Recovery Inventory
    Eric Y H Chen
    Department of Psychiatry, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Aust N Z J Psychiatry 39:493-9. 2005
  7. ncbi request reprint The impact of family experience on the duration of untreated psychosis (DUP) in Hong Kong
    Eric Yu Hai Chen
    Dept of Psychiatry, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Soc Psychiatry Psychiatr Epidemiol 40:350-6. 2005
  8. ncbi request reprint Phenotyping psychosis: room for neurocomputational and content-dependent cognitive endophenotypes?
    Eric Y H Chen
    Department of Psychiatry, University of Hong Kong, Hong Kong
    Cogn Neuropsychiatry 14:451-72. 2009
  9. ncbi request reprint A 3-year prospective study of neurological soft signs in first-episode schizophrenia
    Eric Yu Hai Chen
    Department of Psychiatry, University of Hong Kong Queen Mary Hospital, Pokfulam Road, Hong Kong
    Schizophr Res 75:45-54. 2005
  10. pmc Maintenance treatment with quetiapine versus discontinuation after one year of treatment in patients with remitted first episode psychosis: randomised controlled trial
    Eric Y H Chen
    Department of Psychiatry, University of Hong Kong, Hong Kong
    BMJ 341:c4024. 2010

Collaborators

Detail Information

Publications47

  1. ncbi request reprint Prevalence and course of schizophrenia in a Chinese rural area
    Mao Sheng Ran
    Institute of Mental Health, West China Hospital, West China Medical School of Sichuan University, Chengdu
    Aust N Z J Psychiatry 37:452-7. 2003
    ..To assess the characteristics and factors affecting course of schizophrenia in a Chinese rural area...
  2. ncbi request reprint A prospective 3-year longitudinal study of cognitive predictors of relapse in first-episode schizophrenic patients
    Eric Yu Hai Chen
    Department of Psychiatry, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Schizophr Res 77:99-104. 2005
    ..Cognitive predictors of relapse have been extensively explored only in few long term longitudinal studies of first-episode schizophrenia...
  3. doi request reprint HT1001, a proprietary North American ginseng extract, improves working memory in schizophrenia: a double-blind, placebo-controlled study
    Eric Y H Chen
    Department of Psychiatry, Queen Mary Hospital, University of Hong Kong, Hong Kong, S A R, China
    Phytother Res 26:1166-72. 2012
    ....
  4. pmc Suicide among adults aged 30-49: a psychological autopsy study in Hong Kong
    Paul W C Wong
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, Pokfulam, Hong Kong SAR, PR China
    BMC Public Health 8:147. 2008
    ..A surge in suicide rates in middle age people in Hong Kong and many Asian countries was recently observed. However, there is a paucity of suicide research on this subgroup of people in Asia...
  5. ncbi request reprint Stroop interference and facilitation effects in first-episode schizophrenic patients
    E Y Chen
    Department of Psychiatry, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, Hong Kong
    Schizophr Res 48:29-44. 2001
    ..The increased facilitation effect for patients in their early phase of treatment (but not later) may represent an acute effect of anti-psychotic medication. Its nature and significance require further investigation...
  6. ncbi request reprint Self-administered instrument to measure the patient's experience of recovery after first-episode psychosis: development and validation of the Psychosis Recovery Inventory
    Eric Y H Chen
    Department of Psychiatry, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Aust N Z J Psychiatry 39:493-9. 2005
    ..The Psychosis Recovery Inventory (PRI) is designed to specifically address a number of closely related issues that are faced by patients who are recovering from a first-episode psychosis...
  7. ncbi request reprint The impact of family experience on the duration of untreated psychosis (DUP) in Hong Kong
    Eric Yu Hai Chen
    Dept of Psychiatry, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Soc Psychiatry Psychiatr Epidemiol 40:350-6. 2005
    ..We also studied the effects of pre-morbid adjustment, educational level, living alone, and mode of onset as potential determinants of the duration of untreated psychosis (DUP)...
  8. ncbi request reprint Phenotyping psychosis: room for neurocomputational and content-dependent cognitive endophenotypes?
    Eric Y H Chen
    Department of Psychiatry, University of Hong Kong, Hong Kong
    Cogn Neuropsychiatry 14:451-72. 2009
    ..Cognitive dysfunctions have been widely pursued as target endophenotype in schizophrenia. We critically discuss the promise and limitations of this approach...
  9. ncbi request reprint A 3-year prospective study of neurological soft signs in first-episode schizophrenia
    Eric Yu Hai Chen
    Department of Psychiatry, University of Hong Kong Queen Mary Hospital, Pokfulam Road, Hong Kong
    Schizophr Res 75:45-54. 2005
    ..A higher level of neurological soft signs is related to a lower educational level and an older age at onset, but the level of neurological soft signs does not predict the outcome in terms of relapse or occupational functioning...
  10. pmc Maintenance treatment with quetiapine versus discontinuation after one year of treatment in patients with remitted first episode psychosis: randomised controlled trial
    Eric Y H Chen
    Department of Psychiatry, University of Hong Kong, Hong Kong
    BMJ 341:c4024. 2010
    ..To study rates of relapse in remitted patients with first episode psychosis who either continued or discontinued antipsychotic drugs after at least one year of maintenance treatment...
  11. doi request reprint Three-year outcome of phase-specific early intervention for first-episode psychosis: a cohort study in Hong Kong
    Eric Y H Chen
    Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital Department of Psychiatry, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Early Interv Psychiatry 5:315-23. 2011
    ..The study aimed to determine the effectiveness of phase-specific early intervention in first-episode psychosis...
  12. ncbi request reprint Neurological signs and sustained attention impairment in schizophrenia
    E Y Chen
    Department of Psychiatry, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Eur Arch Psychiatry Clin Neurosci 251:1-5. 2001
    ..The results support the notion of heterogeneity and diversity in neurological signs (even among soft neurological signs) and argue against the use of a single global measure to embrace all soft neurological signs in schizophrenia...
  13. ncbi request reprint A cluster analysis of the circumstances of death in suicides in Hong Kong
    Eric Y H Chen
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, Pokfulam, Hong Kong
    Suicide Life Threat Behav 37:576-84. 2007
    ..Suicide prevention strategy may have to target potential subgroups with specific approaches...
  14. ncbi request reprint The relationship of early premorbid adjustment with negative symptoms and cognitive functions in first-episode schizophrenia: a prospective three-year follow-up study
    Wing Chung Chang
    Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong Electronic address
    Psychiatry Res 209:353-60. 2013
    ..The results highlighted the importance of applying a more refined delineation of premorbid functioning in studying illness outcome. ..
  15. doi request reprint The concurrent and predictive validity of symptomatic remission criteria in first-episode schizophrenia
    Wing Chung Chang
    Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Schizophr Res 143:107-15. 2013
    ..Predictive validity of the proposed remission definition was under-studied. Relationship of remission with subjective quality of life (QoL) was inadequately addressed with inconsistent findings being observed...
  16. doi request reprint Duration of untreated psychosis: relationship with baseline characteristics and three-year outcome in first-episode psychosis
    Wing Chung Chang
    Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Psychiatry Res 198:360-5. 2012
    ..Additionally, it suggested that an adverse impact of treatment delay for psychosis may likely be applied across regions of various ethno-cultural backgrounds...
  17. doi request reprint Prospective relationship between duration of untreated psychosis and 13-year clinical outcome: a first-episode psychosis study
    Jennifer Yee Man Tang
    Department of Psychiatry, The University of Hong Kong, Hong Kong Electronic address
    Schizophr Res 153:1-8. 2014
    ..Although the DUP-outcome relationship is commonly assumed to be linear, the threshold effect has not been adequately examined...
  18. doi request reprint Longitudinal changes in semantic categorization performance after symptomatic remission from first-episode psychosis: a 3-year follow-up study
    Christy Lai Ming Hui
    Department of Psychiatry, University of Hong Kong, Hong Kong
    Schizophr Res 137:118-23. 2012
    ..Overall, the data are suggestive of a state effect in semantic abnormalities rather than a trait effect. The correlation between degree of impairment and symptoms may explain previous inconsistent findings...
  19. doi request reprint Reliability and validity of the life functioning assessment inventory (L-FAI) for patients with psychosis
    Christy Lai Ming Hui
    Department of Psychiatry, Queen Mary Hospital, University of Hong Kong, 102, Pokfulam Road, Hong Kong, Hong Kong
    Soc Psychiatry Psychiatr Epidemiol 48:1687-95. 2013
    ..L-FAI assesses four life domains including work, social relationships, leisure, and homemaking. Specific and concrete anchor points are set in each of these domains...
  20. ncbi request reprint Correlates of insight with symptomatology and executive function in patients with first-episode schizophrenia-spectrum disorder: a longitudinal perspective
    Sherry Kit Wa Chan
    Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, Room 219, New Clinical Building, 102 Pokfulam Road, Hong Kong Electronic address
    Psychiatry Res 216:177-84. 2014
    ..Although the variance explained was small, it suggests better set-shifting capacity facilitates the improvement of insight at an early stage of the illness. ..
  21. doi request reprint Relationship between diminished expression and cognitive impairment in first-episode schizophrenia: a prospective three-year follow-up study
    Wing Chung Chang
    Department of Psychiatry, The University of Hong Kong, Hong Kong Electronic address
    Schizophr Res 152:146-51. 2014
    ..This study aimed to examine cross-sectional and longitudinal relationships of DE with cognitive functions in first-episode schizophrenia utilizing a prospective design...
  22. ncbi request reprint Random number generation deficit in early schizophrenia
    Kevin Ka Shing Chan
    Department of Psychiatry, The University of Hong Kong, SAR, China
    Percept Mot Skills 112:91-103. 2011
    ....
  23. ncbi request reprint Suicide and unemployment: what are the missing links?
    Wincy S C Chan
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, and Department of Social Work and Social Administration, Faculty of Sciences, University of Hong Kong, Pokfulam, Hong Kong, SAR
    Arch Suicide Res 11:327-35. 2007
    ....
  24. ncbi request reprint Cognitive enhancement therapy for schizophrenia
    Mao Sheng Ran
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Lancet 364:2163-5. 2004
  25. ncbi request reprint The effects of a celebrity suicide on suicide rates in Hong Kong
    Paul S F Yip
    HKJC Centre for Suicide Research and Prevention, The University of Hong Kong, Hong Kong SAR, PR China
    J Affect Disord 93:245-52. 2006
    ..We have examined the impact on suicides following the death of a famous Hong Kong pop singer whose death from suicide by jumping from a height, occurred on 1st April 2003, and resulted in extensive and often dramatic media coverage...
  26. ncbi request reprint Suicide in Hong Kong: a case-control psychological autopsy study
    Eric Y H Chen
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, Pokfulam, Hong Kong
    Psychol Med 36:815-25. 2006
    ..In Hong Kong, this issue requires vigorous examination in light of a 50% increase in suicide rate between 1997 and 2003...
  27. doi request reprint Naming psychosis: the Hong Kong experience
    Cindy P Y Chiu
    Department of Psychiatry, University of Hong Kong, Hong Kong SAR, China
    Early Interv Psychiatry 4:270-4. 2010
    ....
  28. ncbi request reprint Cerebral grey, white matter and csf in never-medicated, first-episode schizophrenia
    Siew E Chua
    Department of Psychiatry, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, S A R China
    Schizophr Res 89:12-21. 2007
    ..Ratio of lateral ventricle to caudate volume was bilaterally significantly increased (p<0.005, 2-tailed), which could represent an early biomarker in first-episode, never-medicated schizophrenia...
  29. ncbi request reprint The role of knowledge and motivation in symptom identification accuracy among schizophrenic patients: application of signal detection theory
    Agatha W S Wong
    University of Hong Kong, Hong Kong
    Br J Clin Psychol 45:427-36. 2006
    ..The present study assessed the joint influence of lack of knowledge and motivated denial in schizophrenic patients' low symptom awareness...
  30. ncbi request reprint An instrument to assess mental patients' capacity to appraise and report subjective quality of life
    Josephine G W S Wong
    Department of Psychiatry, The University of Hong Kong, Hong Kong SAR, China
    Qual Life Res 14:687-94. 2005
    ..The CapQOL demonstrated satisfactory psychometric properties. Further validation studies in people with psychosis as well as other mental disabilities are indicated...
  31. ncbi request reprint Impact of untreated psychosis on quality of life in patients with first-episode schizophrenia
    C W Law
    Department of Psychiatry, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong
    Qual Life Res 14:1803-11. 2005
    ..Amongst various clinical parameters, the severity of depressive symptoms correlates most with QOL...
  32. ncbi request reprint Decision-making capacity of inpatients with schizophrenia in Hong Kong
    Josephine G W S Wong
    The Department of Psychiatry, University of Hong Kong, Hong Kong
    J Nerv Ment Dis 193:316-22. 2005
    ..Verbal working memory was a moderate predictor of the ability to understand treatment information. Decision-making impairments and negative treatment attitude were related to the decision not to adhere to medication...
  33. ncbi request reprint Population-attributable risk of suicide conferred by axis I psychiatric diagnoses in a Hong Kong Chinese population
    Sandra Sau Man Chan
    Department of Psychiatry, Chinese University of Hong Kong, Ground Floor, Multicentre, Tai Po Hospital, 9 Chuen On Rd, Tai Po, N T, Hong Kong
    Psychiatr Serv 60:1135-8. 2009
    ..This study was conducted to determine the population-attributable risk (PAR) of completed suicide among Hong Kong Chinese with axis I psychiatric diagnoses...
  34. ncbi request reprint Socio-economic and psychological correlates of suicidality among Hong Kong working-age adults: results from a population-based survey
    Ka Y Liu
    HKJC Centre for Suicide Research and Prevention, University of Hong Kong, Hong Kong
    Psychol Med 36:1759-67. 2006
    ....
  35. ncbi request reprint Detection of non-adherent behaviour in early psychosis
    Christy L M Hui
    Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, China
    Aust N Z J Psychiatry 40:446-51. 2006
    ..The evaluation of adherence is often difficult in the clinical setting. This study compared patient self-reporting and clinician judgment of adherence behaviour in patients with early and chronic schizophrenia...
  36. ncbi request reprint An association study of RGS4 polymorphisms with clinical phenotypes of schizophrenia in a Chinese population
    Hon Cheong So
    Department of Psychiatry, University of Hong Kong, Hong Kong, China
    Am J Med Genet B Neuropsychiatr Genet 147:77-85. 2008
    ..The association with information subtest score suggests an effect of RGS4 on premorbid functioning, which may be related to neurodevelopmental processes. Further independent studies are required to verify our findings...
  37. doi request reprint A naturalistic study of grey matter volume increase after early treatment in anti-psychotic naïve, newly diagnosed schizophrenia
    Michelle Y Deng
    Department of Psychiatry, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Hong Kong, Hong Kong
    Psychopharmacology (Berl) 206:437-46. 2009
    ..Anti-psychotic treatment appears to be associated with striatal volume increase, but how early this change occurs is still unknown...
  38. ncbi request reprint Impaired facilitation of self-control cognition by glucose in patients with schizophrenia: a randomized controlled study
    Chung Ming Leung
    Department of Psychiatry, University of Hong Kong, Hong Kong
    Schizophr Res 156:38-45. 2014
    ..This study aims to investigate whether patient's (a) glucose facilitation effects will be impaired, and (b) will have exaggerated depletion in a self-control task...
  39. doi request reprint Early intervention for psychosis in Hong Kong--the EASY programme
    Jennifer Y M Tang
    Department of Psychiatry, The University of Hong Kong, Hong Kong, China
    Early Interv Psychiatry 4:214-9. 2010
    ..This article aims to describe the Hong Kong experience in developing and implementing an early psychosis programme...
  40. doi request reprint Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population
    Hon Cheong So
    Department of Psychiatry, University of Hong Kong, Hong Kong SAR, China
    Am J Med Genet B Neuropsychiatr Genet 153:103-13. 2010
    ..Taken together, these results suggest that NGC may be a novel candidate gene, and neuregulin signaling pathways may play an important role in schizophrenia...
  41. ncbi request reprint Genetics of schizophrenia spectrum disorders: looking back and peering ahead
    Hon Cheong So
    Department of Psychiatry, The University of Hong Kong, LKS Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Ann Acad Med Singapore 38:436-4. 2009
    ....
  42. ncbi request reprint Blink rate does matter: a study of blink rate, sustained attention, and neurological signs in schizophrenia
    Raymond C K Chan
    Department of Psychiatry, University of Hong Kong, Hong Kong, China
    J Nerv Ment Dis 192:781-3. 2004
    ..There was also a trend for those patients at the upper quartiles to commit more error in a sustained attention task. These findings suggest that blink rate is associated with disinhibition signs in the present sample...
  43. ncbi request reprint What does recovery from schizophrenia mean? Perceptions of long-term patients
    Roger M K Ng
    Department of Psychiatry, Kowloon Hospital, Hong Kong, China
    Int J Soc Psychiatry 54:118-30. 2008
    ..The study investigated the meaning of recovery to eight people with chronic schizophrenia...
  44. doi request reprint Mortality of geriatric and younger patients with schizophrenia in the community
    Mao Sheng Ran
    College of Professional Studies, University of Guam, Mangilao, Guam
    Suicide Life Threat Behav 38:143-51. 2008
    ..Specific intervention strategies for decreasing mortality and suicide should be developed for patients with schizophrenia in different age groups...
  45. ncbi request reprint Suicidal behavior among inpatients with schizophrenia and mood disorders in Chengdu, China
    Mao Sheng Ran
    Institute of Mental Health, West China Hospital, West China Medical School of Sichuan University, Chengdu, China
    Suicide Life Threat Behav 34:311-9. 2004
    ..Mood disorder patients, especially those with major depressive disorder, had more and more serious suicide attempts than the patients with schizophrenia...
  46. ncbi request reprint Characteristics of suicide attempters and nonattempters with schizophrenia in a rural community
    Mao Sheng Ran
    College of Professional Studies, University of Guam, Mangilao, Guam 96923
    Suicide Life Threat Behav 35:694-701. 2005
    ..Early interventions focusing on reducing hopelessness and controlling positive symptoms may help reduce the risk of suicide attempts among patients with schizophrenia...
  47. ncbi request reprint Mortality in people with schizophrenia in rural China: 10-year cohort study
    Mao Sheng Ran
    College of Professional Studies, University of Guam, Mangilao, Guam 96923, USA
    Br J Psychiatry 190:237-42. 2007
    ..Long-term mortality and the risk factors for premature death among patients with schizophrenia living in rural communities are unknown...