Eric Y H Chen

Summary

Affiliation: The University of Hong Kong
Country: China

Publications

  1. ncbi Suicide in Hong Kong: a case-control psychological autopsy study
    Eric Y H Chen
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, Pokfulam, Hong Kong
    Psychol Med 36:815-25. 2006
  2. ncbi Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis
    Christy L M Hui
    Department of Psychiatry, University of Hong Kong, Hong Kong, China Electronic address
    Schizophr Res 150:297-302. 2013
  3. pmc Suicide among adults aged 30-49: a psychological autopsy study in Hong Kong
    Paul W C Wong
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, Pokfulam, Hong Kong SAR, PR China
    BMC Public Health 8:147. 2008
  4. ncbi A cluster analysis of the circumstances of death in suicides in Hong Kong
    Eric Y H Chen
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, Pokfulam, Hong Kong
    Suicide Life Threat Behav 37:576-84. 2007
  5. doi Persistent negative symptoms in first-episode schizophrenia: a prospective three-year follow-up study
    W C Chang
    Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Schizophr Res 133:22-8. 2011
  6. ncbi Impact of physical activity on functioning of patients with first-episode psychosis--a 6 months prospective longitudinal study
    Edwin H M Lee
    Department of Psychiatry, University of Hong Kong, Hong Kong, China Electronic address
    Schizophr Res 150:538-41. 2013
  7. ncbi Suicide and unemployment: what are the missing links?
    Wincy S C Chan
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, and Department of Social Work and Social Administration, Faculty of Sciences, University of Hong Kong, Pokfulam, Hong Kong, SAR
    Arch Suicide Res 11:327-35. 2007
  8. ncbi Socio-economic and psychological correlates of suicidality among Hong Kong working-age adults: results from a population-based survey
    Ka Y Liu
    HKJC Centre for Suicide Research and Prevention, University of Hong Kong, Hong Kong
    Psychol Med 36:1759-67. 2006
  9. pmc Maintenance treatment with quetiapine versus discontinuation after one year of treatment in patients with remitted first episode psychosis: randomised controlled trial
    Eric Y H Chen
    Department of Psychiatry, University of Hong Kong, Hong Kong
    BMJ 341:c4024. 2010
  10. doi A naturalistic study of grey matter volume increase after early treatment in anti-psychotic naïve, newly diagnosed schizophrenia
    Michelle Y Deng
    Department of Psychiatry, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Hong Kong, Hong Kong
    Psychopharmacology (Berl) 206:437-46. 2009

Collaborators

Detail Information

Publications39

  1. ncbi Suicide in Hong Kong: a case-control psychological autopsy study
    Eric Y H Chen
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, Pokfulam, Hong Kong
    Psychol Med 36:815-25. 2006
    ..In Hong Kong, this issue requires vigorous examination in light of a 50% increase in suicide rate between 1997 and 2003...
  2. ncbi Predicting 1-year risk for relapse in patients who have discontinued or continued quetiapine after remission from first-episode psychosis
    Christy L M Hui
    Department of Psychiatry, University of Hong Kong, Hong Kong, China Electronic address
    Schizophr Res 150:297-302. 2013
    ..It is this situation i.e., discontinuation of medication that predictors will be most useful. We identify predictors for relapse in situations of (i) discontinuation and (ii) continuation of maintenance medication...
  3. pmc Suicide among adults aged 30-49: a psychological autopsy study in Hong Kong
    Paul W C Wong
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, Pokfulam, Hong Kong SAR, PR China
    BMC Public Health 8:147. 2008
    ..A surge in suicide rates in middle age people in Hong Kong and many Asian countries was recently observed. However, there is a paucity of suicide research on this subgroup of people in Asia...
  4. ncbi A cluster analysis of the circumstances of death in suicides in Hong Kong
    Eric Y H Chen
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, University of Hong Kong, Pokfulam, Hong Kong
    Suicide Life Threat Behav 37:576-84. 2007
    ..Suicide prevention strategy may have to target potential subgroups with specific approaches...
  5. doi Persistent negative symptoms in first-episode schizophrenia: a prospective three-year follow-up study
    W C Chang
    Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong
    Schizophr Res 133:22-8. 2011
    ..We aimed at evaluating the prevalence and stability of primary negative symptoms, and factors associated with persistent primary negative symptoms in a first-episode sample...
  6. ncbi Impact of physical activity on functioning of patients with first-episode psychosis--a 6 months prospective longitudinal study
    Edwin H M Lee
    Department of Psychiatry, University of Hong Kong, Hong Kong, China Electronic address
    Schizophr Res 150:538-41. 2013
    ..207, P=0.001) at baseline predicted poorer functioning at 6months. Early intervention for psychosis should target to improve patients' physical activity level which may help subsequent functioning. ..
  7. ncbi Suicide and unemployment: what are the missing links?
    Wincy S C Chan
    Hong Kong Jockey Club Centre for Suicide Research and Prevention, and Department of Social Work and Social Administration, Faculty of Sciences, University of Hong Kong, Pokfulam, Hong Kong, SAR
    Arch Suicide Res 11:327-35. 2007
    ....
  8. ncbi Socio-economic and psychological correlates of suicidality among Hong Kong working-age adults: results from a population-based survey
    Ka Y Liu
    HKJC Centre for Suicide Research and Prevention, University of Hong Kong, Hong Kong
    Psychol Med 36:1759-67. 2006
    ....
  9. pmc Maintenance treatment with quetiapine versus discontinuation after one year of treatment in patients with remitted first episode psychosis: randomised controlled trial
    Eric Y H Chen
    Department of Psychiatry, University of Hong Kong, Hong Kong
    BMJ 341:c4024. 2010
    ..To study rates of relapse in remitted patients with first episode psychosis who either continued or discontinued antipsychotic drugs after at least one year of maintenance treatment...
  10. doi A naturalistic study of grey matter volume increase after early treatment in anti-psychotic naïve, newly diagnosed schizophrenia
    Michelle Y Deng
    Department of Psychiatry, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Hong Kong, Hong Kong
    Psychopharmacology (Berl) 206:437-46. 2009
    ..Anti-psychotic treatment appears to be associated with striatal volume increase, but how early this change occurs is still unknown...
  11. doi Cost-effectiveness of an early assessment service for young people with early psychosis in Hong Kong
    Kenny K Wong
    Department of Psychiatry, University of Hong Kong, Queen Mary Hospital, Pok Fu Lam Road, Hong Kong
    Aust N Z J Psychiatry 45:673-80. 2011
    ..The present study examined the cost-effectiveness of the service over a period of 24 months compared to standard care...
  12. ncbi Genetics of schizophrenia spectrum disorders: looking back and peering ahead
    Hon Cheong So
    Department of Psychiatry, The University of Hong Kong, LKS Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Ann Acad Med Singapore 38:436-4. 2009
    ....
  13. doi Naming psychosis: the Hong Kong experience
    Cindy P Y Chiu
    Department of Psychiatry, University of Hong Kong, Hong Kong SAR, China
    Early Interv Psychiatry 4:270-4. 2010
    ....
  14. ncbi The role of knowledge and motivation in symptom identification accuracy among schizophrenic patients: application of signal detection theory
    Agatha W S Wong
    University of Hong Kong, Hong Kong
    Br J Clin Psychol 45:427-36. 2006
    ..The present study assessed the joint influence of lack of knowledge and motivated denial in schizophrenic patients' low symptom awareness...
  15. ncbi Cerebral grey, white matter and csf in never-medicated, first-episode schizophrenia
    Siew E Chua
    Department of Psychiatry, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong, S A R China
    Schizophr Res 89:12-21. 2007
    ..Ratio of lateral ventricle to caudate volume was bilaterally significantly increased (p<0.005, 2-tailed), which could represent an early biomarker in first-episode, never-medicated schizophrenia...
  16. ncbi The effects of a celebrity suicide on suicide rates in Hong Kong
    Paul S F Yip
    HKJC Centre for Suicide Research and Prevention, The University of Hong Kong, Hong Kong SAR, PR China
    J Affect Disord 93:245-52. 2006
    ..We have examined the impact on suicides following the death of a famous Hong Kong pop singer whose death from suicide by jumping from a height, occurred on 1st April 2003, and resulted in extensive and often dramatic media coverage...
  17. ncbi An instrument to assess mental patients' capacity to appraise and report subjective quality of life
    Josephine G W S Wong
    Department of Psychiatry, The University of Hong Kong, Hong Kong SAR, China
    Qual Life Res 14:687-94. 2005
    ..The CapQOL demonstrated satisfactory psychometric properties. Further validation studies in people with psychosis as well as other mental disabilities are indicated...
  18. ncbi Self-administered instrument to measure the patient's experience of recovery after first-episode psychosis: development and validation of the Psychosis Recovery Inventory
    Eric Y H Chen
    Department of Psychiatry, Queen Mary Hospital, Pokfulam Road, Hong Kong
    Aust N Z J Psychiatry 39:493-9. 2005
    ..The Psychosis Recovery Inventory (PRI) is designed to specifically address a number of closely related issues that are faced by patients who are recovering from a first-episode psychosis...
  19. doi HT1001, a proprietary North American ginseng extract, improves working memory in schizophrenia: a double-blind, placebo-controlled study
    Eric Y H Chen
    Department of Psychiatry, Queen Mary Hospital, University of Hong Kong, Hong Kong, S A R, China
    Phytother Res 26:1166-72. 2012
    ....
  20. ncbi Decision-making capacity of inpatients with schizophrenia in Hong Kong
    Josephine G W S Wong
    The Department of Psychiatry, University of Hong Kong, Hong Kong
    J Nerv Ment Dis 193:316-22. 2005
    ..Verbal working memory was a moderate predictor of the ability to understand treatment information. Decision-making impairments and negative treatment attitude were related to the decision not to adhere to medication...
  21. ncbi Phenotyping psychosis: room for neurocomputational and content-dependent cognitive endophenotypes?
    Eric Y H Chen
    Department of Psychiatry, University of Hong Kong, Hong Kong
    Cogn Neuropsychiatry 14:451-72. 2009
    ..Cognitive dysfunctions have been widely pursued as target endophenotype in schizophrenia. We critically discuss the promise and limitations of this approach...
  22. ncbi An association study of RGS4 polymorphisms with clinical phenotypes of schizophrenia in a Chinese population
    Hon Cheong So
    Department of Psychiatry, University of Hong Kong, Hong Kong, China
    Am J Med Genet B Neuropsychiatr Genet 147:77-85. 2008
    ..The association with information subtest score suggests an effect of RGS4 on premorbid functioning, which may be related to neurodevelopmental processes. Further independent studies are required to verify our findings...
  23. ncbi Blink rate does matter: a study of blink rate, sustained attention, and neurological signs in schizophrenia
    Raymond C K Chan
    Department of Psychiatry, University of Hong Kong, Hong Kong, China
    J Nerv Ment Dis 192:781-3. 2004
    ..There was also a trend for those patients at the upper quartiles to commit more error in a sustained attention task. These findings suggest that blink rate is associated with disinhibition signs in the present sample...
  24. ncbi The differential clinical and neurocognitive profiles of COMT SNP rs165599 genotypes in schizophrenia
    Raymond C K Chan
    Neuropsychology and Applied Cognitive Neuroscience Laboratory, Department of Psychology, Sun Yat Sen University, Guangzhou, China
    J Int Neuropsychol Soc 11:202-4. 2005
  25. ncbi The components of executive functioning in a cohort of patients with chronic schizophrenia: a multiple single-case study design
    Raymond C K Chan
    Neuropsychology and Applied Cognitive Neuroscience Laboratory, Department of Psychology, Sun Yat Sen University, Guangzhou 510275, China
    Schizophr Res 81:173-89. 2006
    ..The differential breakdown for the executive functioning performance across the participants suggests that the fractionation of central executive functioning occurs in schizophrenia...
  26. ncbi Neurological abnormalities in Chinese schizophrenic patients
    Raymond C K Chan
    Neuropsychology and Applied Cognitive Neuroscience Laboratory, Institute of Psychology, Chinese Academy of Sciences, Beijing, China
    Behav Neurol 18:171-81. 2007
    ..This study attempted to examine the prevalence and type of neurological signs in Chinese patients with schizophrenia...
  27. ncbi Neurocognitive deficits in first-episode schizophrenic patients and their first-degree relatives
    Xiaohong Ma
    Psychiatric Laboratory and Department of Psychiatry, West China Hospital, Sichuan University, Chengdu, P R China
    Am J Med Genet B Neuropsychiatr Genet 144:407-16. 2007
    ..These patterns of neurocognitive deficits may represent "endophenotypes" denoting varying degrees of vulnerability to schizophrenia and may be of value in future molecular genetic studies...
  28. ncbi Transition to psychosis: 6-month follow-up of a Chinese high-risk group in Hong Kong
    May M L Lam
    Kwai Chung Hospital, New Territorries, Hong Kong SAR
    Aust N Z J Psychiatry 40:414-20. 2006
    ....
  29. ncbi Impact of untreated psychosis on quality of life in patients with first-episode schizophrenia
    C W Law
    Department of Psychiatry, Queen Mary Hospital, The University of Hong Kong, 102 Pokfulam Road, Hong Kong
    Qual Life Res 14:1803-11. 2005
    ..Amongst various clinical parameters, the severity of depressive symptoms correlates most with QOL...
  30. ncbi A comparison between schizophrenia patients and healthy controls on the expression of attentional blink in a rapid serial visual presentation (RSVP) paradigm
    Vinci Cheung
    Department of Psychiatry, The University of Hong Kong, Pokulam, PRC
    Schizophr Bull 28:443-58. 2002
    ..The present results add to the extensive literature on the nature and specification of attentional dysfunction implicated in schizophrenia...
  31. ncbi What does recovery from schizophrenia mean? Perceptions of long-term patients
    Roger M K Ng
    Department of Psychiatry, Kowloon Hospital, Hong Kong, China
    Int J Soc Psychiatry 54:118-30. 2008
    ..The study investigated the meaning of recovery to eight people with chronic schizophrenia...
  32. ncbi Detection of non-adherent behaviour in early psychosis
    Christy L M Hui
    Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, China
    Aust N Z J Psychiatry 40:446-51. 2006
    ..The evaluation of adherence is often difficult in the clinical setting. This study compared patient self-reporting and clinician judgment of adherence behaviour in patients with early and chronic schizophrenia...
  33. ncbi Prose memory deficits associated with schizophrenia
    Tatia M C Lee
    Neuropsychology Laboratory, The University of Hong Kong, Hong Kong, China
    Schizophr Res 81:199-209. 2006
    ..These results may have important implications for rehabilitation of verbal declarative memory deficits in schizophrenia...
  34. ncbi Specific executive dysfunction in patients with first-episode medication-naïve schizophrenia
    Raymond C K Chan
    Neuropsychology and Applied Cognitive Neuroscience Laboratory, Department of Psychology, Sun Yat Sen University, Guangzhou, China
    Schizophr Res 82:51-64. 2006
    ..This differential breakdown of executive function components is unlikely to be an artefact of general intellectual decline or memory impairment in schizophrenia...
  35. ncbi Perceptions on remission and recovery in schizophrenia
    Hector W H Tsang
    Psychopathology 40:469. 2007
  36. pmc Changes in serum lipids, independent of weight, are associated with changes in symptoms during long-term clozapine treatment
    Ric M Procyshyn
    Department of Research, Riverview Hospital, Port Coquitlam, BC, Canada
    J Psychiatry Neurosci 32:331-8. 2007
    ..The primary objective of this study was to determine whether an increase in serum lipids is associated with improvement in schizophrenia symptoms during steady state treatment with clozapine...
  37. ncbi Clozapine alone versus clozapine and risperidone with refractory schizophrenia
    William G Honer
    Centre for Complex Disorders and the Department of Psychiatry, University of British Columbia, Vancouver General Hospital Research Pavilion, Vancouver, Canada
    N Engl J Med 354:472-82. 2006
    ..The treatment of schizophrenia with multiple antipsychotic drugs is common, but the benefits and risks are not known...
  38. ncbi The contribution of a cognitive bias against disconfirmatory evidence (BADE) to delusions: a study in an Asian sample with first episode schizophrenia spectrum disorders
    Todd S Woodward
    Schizophr Res 83:297-8. 2006
  39. ncbi Asymmetric lateral ventricular enlargement in Chinese with 1st episode schizophrenia
    Siew E Chua
    Schizophr Res 57:123-4. 2002