Wing Keung Chan

Summary

Affiliation: The University of Hong Kong
Country: China

Publications

  1. ncbi Ganoderma lucidum polysaccharides can induce human monocytic leukemia cells into dendritic cells with immuno-stimulatory function
    Wing Keung Chan
    Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, PR China
    J Hematol Oncol 1:9. 2008
  2. ncbi Response of human dendritic cells to different immunomodulatory polysaccharides derived from mushroom and barley
    Wing Keung Chan
    Department of Paediatrics and Adolescent Medicine, Hong Kong Jockey Club Clinical Research Center, Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Int Immunol 19:891-9. 2007
  3. ncbi MHC expression kinetics and immunogenicity of mesenchymal stromal cells after short-term IFN-gamma challenge
    Wing Keung Chan
    Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
    Exp Hematol 36:1545-55. 2008
  4. ncbi Ganoderma lucidum mycelium and spore extracts as natural adjuvants for immunotherapy
    Wing Keung Chan
    Department of Paediatrics and Adolescent Medicine, Hong Kong Jockey Club Clinical Research Centre, Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China
    J Altern Complement Med 11:1047-57. 2005
  5. ncbi Brazilian green propolis and its constituent, Artepillin C inhibits allogeneic activated human CD4 T cells expansion and activation
    Ka Wai Cheung
    Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
    J Ethnopharmacol 138:463-71. 2011
  6. ncbi Prolonged exposure to bacterial toxins downregulated expression of toll-like receptors in mesenchymal stromal cell-derived osteoprogenitors
    Irene Fung Ying Mo
    Department of Paediatrics and Adolescent Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong, PR China
    BMC Cell Biol 9:52. 2008
  7. ncbi The effects of beta-glucan on human immune and cancer cells
    Godfrey Chi Fung Chan
    Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
    J Hematol Oncol 2:25. 2009

Collaborators

Detail Information

Publications7

  1. ncbi Ganoderma lucidum polysaccharides can induce human monocytic leukemia cells into dendritic cells with immuno-stimulatory function
    Wing Keung Chan
    Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong, PR China
    J Hematol Oncol 1:9. 2008
    ..The question of how leukemic cells especially in monocytic lineage respond to GL-PS stimuli remains unclear...
  2. ncbi Response of human dendritic cells to different immunomodulatory polysaccharides derived from mushroom and barley
    Wing Keung Chan
    Department of Paediatrics and Adolescent Medicine, Hong Kong Jockey Club Clinical Research Center, Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Int Immunol 19:891-9. 2007
    ..Our study also provides a reproducible biological platform for comparing the potential therapeutic effects of different herbal-derived polysaccharides in the future...
  3. ncbi MHC expression kinetics and immunogenicity of mesenchymal stromal cells after short-term IFN-gamma challenge
    Wing Keung Chan
    Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
    Exp Hematol 36:1545-55. 2008
    ..This information is helpful to delineate how human MSCs can be modulated by IFN-gamma in different clinical scenarios...
  4. ncbi Ganoderma lucidum mycelium and spore extracts as natural adjuvants for immunotherapy
    Wing Keung Chan
    Department of Paediatrics and Adolescent Medicine, Hong Kong Jockey Club Clinical Research Centre, Faculty of Medicine, The University of Hong Kong, Hong Kong, SAR, China
    J Altern Complement Med 11:1047-57. 2005
    ..CONCLUSION: These findings provide evidences that GL-M has immunomodulating effects on human immune cells and therefore can be used as a natural adjuvant for cancer immunotherapy with DCs...
  5. ncbi Brazilian green propolis and its constituent, Artepillin C inhibits allogeneic activated human CD4 T cells expansion and activation
    Ka Wai Cheung
    Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
    J Ethnopharmacol 138:463-71. 2011
    ..All these can be linked to the modulation of immune function. Therefore, it will be relevant for us to find out whether there is any novel compound that can account for such action and the mechanism involved...
  6. ncbi Prolonged exposure to bacterial toxins downregulated expression of toll-like receptors in mesenchymal stromal cell-derived osteoprogenitors
    Irene Fung Ying Mo
    Department of Paediatrics and Adolescent Medicine, Faculty of Medicine, The University of Hong Kong, Hong Kong, PR China
    BMC Cell Biol 9:52. 2008
    ..This study investigated whether proliferation and osteogenic differentiation of MSCs would be affected by potent gram-positive and gram-negative derived bacterial toxins commonly found in human settings...
  7. ncbi The effects of beta-glucan on human immune and cancer cells
    Godfrey Chi Fung Chan
    Department of Paediatrics and Adolescent Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong
    J Hematol Oncol 2:25. 2009
    ..Future effort should direct at performing well-designed clinical trials to verify the actual clinical efficacy of beta-glucans or beta-glucans containing compounds...