Shun Wan Chan

Summary

Affiliation: The Hong Kong Polytechnic University
Country: China

Publications

  1. pmc Suppression of diet-induced hypercholesterolemia by turtle jelly, a traditional chinese functional food, in rats
    Jian Hong Wu
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, 518057 Shenzhen, China
    Evid Based Complement Alternat Med 2012:320304. 2012
  2. doi request reprint Panax ginseng, Rhodiola rosea and Schisandra chinensis
    Shun Wan Chan
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Int J Food Sci Nutr 63:75-81. 2012
  3. doi request reprint Serum nitric oxide synthase activity is a novel predictor of impaired vasorelaxation in rats
    Enoch Chan
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Clin Exp Pharmacol Physiol 39:894-6. 2012
  4. doi request reprint A review of the anticancer and immunomodulatory effects of Lycium barbarum fruit
    Wai Man Tang
    Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, People s Republic of China
    Inflammopharmacology 20:307-14. 2012
  5. doi request reprint A review of the pharmacological effects of Arctium lappa (burdock)
    Yuk Shing Chan
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, People s Republic of China
    Inflammopharmacology 19:245-54. 2011
  6. doi request reprint Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis
    Wing Yan Li
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Inflammopharmacology 22:127-34. 2014
  7. doi request reprint Chlorogenic acid exhibits cholesterol lowering and fatty liver attenuating properties by up-regulating the gene expression of PPAR-α in hypercholesterolemic rats induced with a high-cholesterol diet
    Chun Wai Wan
    Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, China
    Phytother Res 27:545-51. 2013
  8. doi request reprint Danshensu is the major marker for the antioxidant and vasorelaxation effects of Danshen (Salvia miltiorrhiza) water-extracts produced by different heat water-extractions
    Xuelin Zhou
    School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China
    Phytomedicine 19:1263-9. 2012
  9. doi request reprint A review of the cardiovascular benefits and antioxidant properties of allicin
    Jackie Yan Yan Chan
    Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, PR China
    Phytother Res 27:637-46. 2013
  10. doi request reprint Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes
    Wing Yan Li
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Pharm Biol 51:1175-81. 2013

Collaborators

  • Ri fu Yang
  • John H K Yeung
  • Enoch Chan
  • Jian Hong Wu
  • Peter Hoi Fu Yu
  • Yiu Wa Kwan
  • Robbie Yat Kan Chan
  • Simon Ming Yuen Lee
  • George Pak Heng Leung
  • Chun Wai Wan
  • Wing Yan Li
  • De Jian Guo
  • Ching Yee Kwok
  • Janet Yuen Yan Chan
  • Chun Mei Li
  • Jackie Yan Yan Chan
  • Xuelin Zhou
  • Wai Man Tang
  • Tsz Shan Kam
  • Yuk Shing Chan
  • Yam Fung Ng
  • Huan Zhang
  • Zi Dong Guo
  • Zhen yu He
  • Wing Kwan Pin
  • Candy Ngai Yan Wong
  • Man Sau Wong
  • Marcus Ho Yin Wong
  • Xue Lian Tian
  • Xiao Li Dong
  • Ailsa Chui Ying Yuen
  • Tai qiu Qiu
  • Qing Hua Wang
  • Jia Ming Yang
  • Pui Long Kwan
  • Pui Man Hoi
  • Penelope M Y Or
  • Pou Seng Choi
  • Francis F Y Lam
  • Robbie Chan
  • Wing Fat-Yiu
  • Kit San Yuen
  • Yee Ki Lee
  • Ho Pui Ho
  • Yan Deng
  • Cho Yee Wong
  • Yuan Lan Shu
  • Siu Kai Kong
  • Fan Li
  • Hui Ling Tseng
  • Chi On Chan
  • Daniel Kam Wah Mok
  • Sin Ming Chiu
  • Xing Xian Liu
  • Ming Fai Chan
  • Shun Yin Sze
  • Kit Yee Leung
  • Ivan Ying Ming Chung
  • Long Ni Cheng
  • Siu Hung Tsui
  • Christina Chui Wa Poon
  • Chi Hang So
  • Sai Wang Seto
  • Kar Man Ng
  • Alice Lai Shan Au
  • Cynthia Ying Kat Wong

Detail Information

Publications16

  1. pmc Suppression of diet-induced hypercholesterolemia by turtle jelly, a traditional chinese functional food, in rats
    Jian Hong Wu
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, 518057 Shenzhen, China
    Evid Based Complement Alternat Med 2012:320304. 2012
    ..The results revealed that TJ could block the downregulation of LDLR and PEPCK and upregulation of PPARα mRNA and protein expressions in the livers of rats fed with hypercholesterolemic diet...
  2. doi request reprint Panax ginseng, Rhodiola rosea and Schisandra chinensis
    Shun Wan Chan
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Int J Food Sci Nutr 63:75-81. 2012
    ..Thus, in most cases, the art of the TCM practitioner is to prescribe these herbs after a complete evaluation of overall heath status of the patients...
  3. doi request reprint Serum nitric oxide synthase activity is a novel predictor of impaired vasorelaxation in rats
    Enoch Chan
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Clin Exp Pharmacol Physiol 39:894-6. 2012
    ..4. This finding is a good foundation for the development of a simple and low-cost alternative for diagnosing vascular diseases and evaluating the effectiveness of drugs on the vascular system in patients...
  4. doi request reprint A review of the anticancer and immunomodulatory effects of Lycium barbarum fruit
    Wai Man Tang
    Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, People s Republic of China
    Inflammopharmacology 20:307-14. 2012
    ..It is not known whether there are any undesirable effects. Further studies on its pharmacological mechanisms and toxicology could facilitate a safe usage of this TCM herb...
  5. doi request reprint A review of the pharmacological effects of Arctium lappa (burdock)
    Yuk Shing Chan
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, People s Republic of China
    Inflammopharmacology 19:245-54. 2011
    ..However, it is also essential to be aware of the side effects of burdock including contact dermatitis and other allergic/inflammatory responses that might be evoked by burdock...
  6. doi request reprint Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis
    Wing Yan Li
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Inflammopharmacology 22:127-34. 2014
    ..These results suggest that emodin could induce growth inhibition and apoptosis in A549 cells through modifying the extrinsic apoptotic pathways and the induction of cell cycle arrest...
  7. doi request reprint Chlorogenic acid exhibits cholesterol lowering and fatty liver attenuating properties by up-regulating the gene expression of PPAR-α in hypercholesterolemic rats induced with a high-cholesterol diet
    Chun Wai Wan
    Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, China
    Phytother Res 27:545-51. 2013
    ..The hypocholesterolemic functions of chlorogenic acid are probably due to the increase in fatty acids unitization in liver via the up-regulation of peroxisome proliferation-activated receptor α mRNA...
  8. doi request reprint Danshensu is the major marker for the antioxidant and vasorelaxation effects of Danshen (Salvia miltiorrhiza) water-extracts produced by different heat water-extractions
    Xuelin Zhou
    School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China
    Phytomedicine 19:1263-9. 2012
    ..Danshensu is, therefore, a useful marker for the quality control of Danshen water-extracts in antioxidant and vasodilation, while tanshinone IIA for anti-apoptotic potential of different extracts...
  9. doi request reprint A review of the cardiovascular benefits and antioxidant properties of allicin
    Jackie Yan Yan Chan
    Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, PR China
    Phytother Res 27:637-46. 2013
    ..Other pharmacological benefits such as anticancer and antimicrobial activities were also discussed. It is concluded that allicin can be potentially developed into a health product for the cardiovascular system...
  10. doi request reprint Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes
    Wing Yan Li
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Pharm Biol 51:1175-81. 2013
    ..Development of therapeutic agents that can inhibit growth and induce apoptosis in breast cancer cells can help solve the problem. Emodin is an active anthraquinone that has been reported to have diverse biological effects...
  11. ncbi request reprint Evaluation of anti-oxidant capacity of root of Scutellaria baicalensis Georgi, in comparison with roots of Polygonum multiflorum Thunb and Panax ginseng CA Meyer
    Enoch Chan
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, China
    Am J Chin Med 38:815-27. 2010
    ..This shows that Huangqin could be an effective dietary anti-oxidant that can be consumed regularly as a functional food for the prevention of oxidant/free radical-related diseases...
  12. doi request reprint Ligusticum chuanxiong prevents ovariectomy-induced liver and vascular damage in rats
    Chun Mei Li
    College of Light Industry and Food, South China University of Technology, Guangzhou, China
    Am J Chin Med 41:831-48. 2013
    ..Taken together, LC may be a promising natural supplement for postmenopausal women to prevent NAFLD and CVDs. ..
  13. doi request reprint Enhancement of in vitro and in vivo anticancer activities of polysaccharide peptide from Grifola frondosa by chemical modifications
    Janet Yuen Yan Chan
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, China
    Pharm Biol 49:1114-20. 2011
    ..Grifola frondosa (Polyporaceae), maitake, is a widely consumed edible mushroom in some Asian countries. The fruit bodies and mycelia of maitake have shown different bioactive compounds with anticancer and other therapeutic properties...
  14. doi request reprint Effects and mechanism of turmeric vasorelaxation of the thoracic aorta in hypercholesterolemic rats
    Tsz Shan Kam
    Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Kowloon, Hong Kong, China
    J Med Food 15:190-9. 2012
    ....
  15. ncbi request reprint Extract of Scutellaria baicalensis Georgi root exerts protection against myocardial ischemia-reperfusion injury in rats
    Enoch Chan
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong
    Am J Chin Med 39:693-704. 2011
    ..The Sb extract could additionally enhance acetylcholine-induced vasorelaxation. It was proposed that the Sb extract exerted its cardioprotection by stimulating the catalase activity and improving vascular elasticity...