Shun Wan Chan

Summary

Affiliation: The Hong Kong Polytechnic University
Country: China

Publications

  1. pmc Suppression of diet-induced hypercholesterolemia by turtle jelly, a traditional chinese functional food, in rats
    Jian Hong Wu
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, 518057 Shenzhen, China
    Evid Based Complement Alternat Med 2012:320304. 2012
  2. doi request reprint Panax ginseng, Rhodiola rosea and Schisandra chinensis
    Shun Wan Chan
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Int J Food Sci Nutr 63:75-81. 2012
  3. doi request reprint Serum nitric oxide synthase activity is a novel predictor of impaired vasorelaxation in rats
    Enoch Chan
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Clin Exp Pharmacol Physiol 39:894-6. 2012
  4. doi request reprint A review of the anticancer and immunomodulatory effects of Lycium barbarum fruit
    Wai Man Tang
    Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, People s Republic of China
    Inflammopharmacology 20:307-14. 2012
  5. doi request reprint A review of the pharmacological effects of Arctium lappa (burdock)
    Yuk Shing Chan
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, People s Republic of China
    Inflammopharmacology 19:245-54. 2011
  6. doi request reprint Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis
    Wing Yan Li
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Inflammopharmacology 22:127-34. 2014
  7. doi request reprint Chlorogenic acid exhibits cholesterol lowering and fatty liver attenuating properties by up-regulating the gene expression of PPAR-α in hypercholesterolemic rats induced with a high-cholesterol diet
    Chun Wai Wan
    Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, China
    Phytother Res 27:545-51. 2013
  8. doi request reprint Danshensu is the major marker for the antioxidant and vasorelaxation effects of Danshen (Salvia miltiorrhiza) water-extracts produced by different heat water-extractions
    Xuelin Zhou
    School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China
    Phytomedicine 19:1263-9. 2012
  9. doi request reprint Allicin protects rat cardiomyoblasts (H9c2 cells) from hydrogen peroxide-induced oxidative injury through inhibiting the generation of intracellular reactive oxygen species
    Jackie Yan Yan Chan
    Department of Applied Biology and Chemical Technology, Food Safety and Technology Research Centre, The Hong Kong Polytechnic University, Hong Kong, China
    Int J Food Sci Nutr 65:868-73. 2014
  10. doi request reprint A review of the cardiovascular benefits and antioxidant properties of allicin
    Jackie Yan Yan Chan
    Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, PR China
    Phytother Res 27:637-46. 2013

Collaborators

  • Ri fu Yang
  • John H K Yeung
  • Enoch Chan
  • Yiu Wa Kwan
  • Jian Hong Wu
  • Robbie Yat Kan Chan
  • George Pak Heng Leung
  • Simon Ming Yuen Lee
  • Peter Hoi Fu Yu
  • Chun Wai Wan
  • Yam Fung Ng
  • Jackie Yan Yan Chan
  • Wing Yan Li
  • Tung Ting Sham
  • Philip Chiu Tsun Tang
  • Daniel Kam Wah Mok
  • De Jian Guo
  • Ching Yee Kwok
  • Janet Yuen Yan Chan
  • Rachel Wai Sum Li
  • Chun Mei Li
  • Chi On Chan
  • Ivan Ying Ming Chung
  • Xuelin Zhou
  • Wai Man Tang
  • Tsz Shan Kam
  • Yuk Shing Chan
  • Maggie Pui Man Hoi
  • Cui Yang
  • You hua Wang
  • Zi Dong Guo
  • Michael Gyda
  • Huan Zhang
  • Wing Sum Lam
  • Jian Mei Yang
  • Susan Ho
  • Hei Tung Tsui
  • Wing Kwan Pin
  • Marcus Ho Yin Wong
  • Ailsa Chui Ying Yuen
  • Man Sau Wong
  • Candy Ngai Yan Wong
  • Xiao Li Dong
  • Tai qiu Qiu
  • Zhen yu He
  • Xue Lian Tian
  • Kit San Yuen
  • Yan Deng
  • Fan Li
  • Siu Kai Kong
  • Sin Ming Chiu
  • Hui Ling Tseng
  • Robbie Chan
  • Pou Seng Choi
  • Wing Fat-Yiu
  • Yuan Lan Shu
  • Penelope M Y Or
  • Jia Ming Yang
  • Francis F Y Lam
  • Pui Long Kwan
  • Qing Hua Wang
  • Ho Pui Ho
  • Pui Man Hoi
  • Yee Ki Lee
  • Cho Yee Wong
  • Siu Hung Tsui
  • Long Ni Cheng
  • Ming Fai Chan
  • Kit Yee Leung
  • Xing Xian Liu
  • Shun Yin Sze
  • Chi Hang So
  • Christina Chui Wa Poon
  • Sai Wang Seto
  • Kar Man Ng
  • Alice Lai Shan Au
  • Cynthia Ying Kat Wong

Detail Information

Publications21

  1. pmc Suppression of diet-induced hypercholesterolemia by turtle jelly, a traditional chinese functional food, in rats
    Jian Hong Wu
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, 518057 Shenzhen, China
    Evid Based Complement Alternat Med 2012:320304. 2012
    ..The results revealed that TJ could block the downregulation of LDLR and PEPCK and upregulation of PPARα mRNA and protein expressions in the livers of rats fed with hypercholesterolemic diet...
  2. doi request reprint Panax ginseng, Rhodiola rosea and Schisandra chinensis
    Shun Wan Chan
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Int J Food Sci Nutr 63:75-81. 2012
    ..Thus, in most cases, the art of the TCM practitioner is to prescribe these herbs after a complete evaluation of overall heath status of the patients...
  3. doi request reprint Serum nitric oxide synthase activity is a novel predictor of impaired vasorelaxation in rats
    Enoch Chan
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Clin Exp Pharmacol Physiol 39:894-6. 2012
    ..4. This finding is a good foundation for the development of a simple and low-cost alternative for diagnosing vascular diseases and evaluating the effectiveness of drugs on the vascular system in patients...
  4. doi request reprint A review of the anticancer and immunomodulatory effects of Lycium barbarum fruit
    Wai Man Tang
    Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, People s Republic of China
    Inflammopharmacology 20:307-14. 2012
    ..It is not known whether there are any undesirable effects. Further studies on its pharmacological mechanisms and toxicology could facilitate a safe usage of this TCM herb...
  5. doi request reprint A review of the pharmacological effects of Arctium lappa (burdock)
    Yuk Shing Chan
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, People s Republic of China
    Inflammopharmacology 19:245-54. 2011
    ..However, it is also essential to be aware of the side effects of burdock including contact dermatitis and other allergic/inflammatory responses that might be evoked by burdock...
  6. doi request reprint Emodin elicits cytotoxicity in human lung adenocarcinoma A549 cells through inducing apoptosis
    Wing Yan Li
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Inflammopharmacology 22:127-34. 2014
    ..These results suggest that emodin could induce growth inhibition and apoptosis in A549 cells through modifying the extrinsic apoptotic pathways and the induction of cell cycle arrest...
  7. doi request reprint Chlorogenic acid exhibits cholesterol lowering and fatty liver attenuating properties by up-regulating the gene expression of PPAR-α in hypercholesterolemic rats induced with a high-cholesterol diet
    Chun Wai Wan
    Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, China
    Phytother Res 27:545-51. 2013
    ..The hypocholesterolemic functions of chlorogenic acid are probably due to the increase in fatty acids unitization in liver via the up-regulation of peroxisome proliferation-activated receptor α mRNA...
  8. doi request reprint Danshensu is the major marker for the antioxidant and vasorelaxation effects of Danshen (Salvia miltiorrhiza) water-extracts produced by different heat water-extractions
    Xuelin Zhou
    School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong, China
    Phytomedicine 19:1263-9. 2012
    ..Danshensu is, therefore, a useful marker for the quality control of Danshen water-extracts in antioxidant and vasodilation, while tanshinone IIA for anti-apoptotic potential of different extracts...
  9. doi request reprint Allicin protects rat cardiomyoblasts (H9c2 cells) from hydrogen peroxide-induced oxidative injury through inhibiting the generation of intracellular reactive oxygen species
    Jackie Yan Yan Chan
    Department of Applied Biology and Chemical Technology, Food Safety and Technology Research Centre, The Hong Kong Polytechnic University, Hong Kong, China
    Int J Food Sci Nutr 65:868-73. 2014
    ..For the observed protective effect on H9c2 cells, allicin might also be effective in reducing free radical-induced myocardial cell death in ischemic condition...
  10. doi request reprint A review of the cardiovascular benefits and antioxidant properties of allicin
    Jackie Yan Yan Chan
    Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, SAR, PR China
    Phytother Res 27:637-46. 2013
    ..Other pharmacological benefits such as anticancer and antimicrobial activities were also discussed. It is concluded that allicin can be potentially developed into a health product for the cardiovascular system...
  11. pmc A review on the traditional Chinese medicinal herbs and formulae with hypolipidemic effect
    Tung Ting Sham
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong
    Biomed Res Int 2014:925302. 2014
    ..Hyperlipidemic patients should be warned about the potential risks of herb-drug interactions, particularly those taking anticoagulants and antiplatelet drugs. ..
  12. pmc Relaxation effect of abacavir on rat basilar arteries
    Rachel Wai Sum Li
    Department of Pharmacology and Pharmacy, Faculty of Medicine, The University of Hong Kong, Hong Kong, China
    PLoS ONE 10:e0123043. 2015
    ..In addition, based on the structural similarity between abacavir and adenosine, we propose that abacavir may affect vascular contractility through endogenous adenosine release or adenosine receptors in blood vessels...
  13. doi request reprint Emodin induces cytotoxic effect in human breast carcinoma MCF-7 cell through modulating the expression of apoptosis-related genes
    Wing Yan Li
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Pharm Biol 51:1175-81. 2013
    ..Development of therapeutic agents that can inhibit growth and induce apoptosis in breast cancer cells can help solve the problem. Emodin is an active anthraquinone that has been reported to have diverse biological effects...
  14. doi request reprint Semen Astragali Complanati: an ethnopharmacological, phytochemical and pharmacological review
    Yam Fung Ng
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China Food Safety and Technology Research Centre, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    J Ethnopharmacol 155:39-53. 2014
    ....
  15. doi request reprint Resveratrol and cardiovascular health--promising therapeutic or hopeless illusion?
    Philip Chiu Tsun Tang
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong, China
    Pharmacol Res 90:88-115. 2014
    ....
  16. ncbi request reprint Evaluation of anti-oxidant capacity of root of Scutellaria baicalensis Georgi, in comparison with roots of Polygonum multiflorum Thunb and Panax ginseng CA Meyer
    Enoch Chan
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, China
    Am J Chin Med 38:815-27. 2010
    ..This shows that Huangqin could be an effective dietary anti-oxidant that can be consumed regularly as a functional food for the prevention of oxidant/free radical-related diseases...
  17. doi request reprint Ligusticum chuanxiong prevents ovariectomy-induced liver and vascular damage in rats
    Chun Mei Li
    College of Light Industry and Food, South China University of Technology, Guangzhou, China
    Am J Chin Med 41:831-48. 2013
    ..Taken together, LC may be a promising natural supplement for postmenopausal women to prevent NAFLD and CVDs. ..
  18. doi request reprint Enhancement of in vitro and in vivo anticancer activities of polysaccharide peptide from Grifola frondosa by chemical modifications
    Janet Yuen Yan Chan
    Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong SAR, China
    Pharm Biol 49:1114-20. 2011
    ..Grifola frondosa (Polyporaceae), maitake, is a widely consumed edible mushroom in some Asian countries. The fruit bodies and mycelia of maitake have shown different bioactive compounds with anticancer and other therapeutic properties...
  19. doi request reprint Effects and mechanism of turmeric vasorelaxation of the thoracic aorta in hypercholesterolemic rats
    Tsz Shan Kam
    Department of Applied Biology and Chemical Technology, Hong Kong Polytechnic University, Kowloon, Hong Kong, China
    J Med Food 15:190-9. 2012
    ....
  20. ncbi request reprint Extract of Scutellaria baicalensis Georgi root exerts protection against myocardial ischemia-reperfusion injury in rats
    Enoch Chan
    State Key Laboratory of Chinese Medicine and Molecular Pharmacology, Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hong Kong
    Am J Chin Med 39:693-704. 2011
    ..The Sb extract could additionally enhance acetylcholine-induced vasorelaxation. It was proposed that the Sb extract exerted its cardioprotection by stimulating the catalase activity and improving vascular elasticity...