Genomes and Genes


Danny Chan


Affiliation: The University of Hong Kong
Country: China


  1. Zhang Y, Xiong C, Kudelko M, Li Y, Wang C, Wong Y, et al. Early onset of disc degeneration in SM/J mice is associated with changes in ion transport systems and fibrotic events. Matrix Biol. 2018;70:123-139 pubmed publisher
    ..The proteomic data has been deposited to the ProteomeXchange Consortium via the PRIDE [1] partner repository with the dataset identifier PXD008784. ..
  2. Shen W, Shen Y, Lam Y, Chan D. Live Imaging of Planaria. Methods Mol Biol. 2018;1774:507-518 pubmed publisher
    ..In combination with cell-permeable fluorescent dyes, this immobilization method allows for the time-lapse imaging of planaria during regeneration and other physiological processes. ..
  3. Yee A, Lam M, Tam V, Chan W, Chu I, Cheah K, et al. Fibrotic-like changes in degenerate human intervertebral discs revealed by quantitative proteomic analysis. Osteoarthritis Cartilage. 2016;24:503-13 pubmed publisher
    ..The nature of the ECM changes, together with observed decreased in solubility and changes in fibril diameter is consistent with a fibrotic-like environment. ..
  4. Bach F, Zhang Y, Miranda Bedate A, Verdonschot L, Bergknut N, Creemers L, et al. Increased caveolin-1 in intervertebral disc degeneration facilitates repair. Arthritis Res Ther. 2016;18:59 pubmed publisher
    ..Further studies are needed to investigate how caveolin-1 modifies other signaling pathways and facilitates IVD repair. ..