Research Topics
| Annie Oo ChanSummaryAffiliation: The University of Hong Kong Country: China Publications
| Collaborators
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Detail Information
Publications
Differing coping mechanisms, stress level and anorectal physiology in patients with functional constipationAnnie Oo Chan
Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
World J Gastroenterol 11:5362-6. 2005..To investigate coping mechanisms, constipation symptoms and anorectal physiology in 80 constipated subjects and 18 controls...
Stability of E-cadherin methylation status in gastric mucosa associated with histology changesA O O Chan
Division of Gastroenterology and Hepatology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
Aliment Pharmacol Ther 24:831-6. 2006..We have previously shown reversal of E-cadherin methylation in gastric mucosa from patients with dyspepsia at week 6 after Helicobacter pylori-eradication therapy. But the long-term methylation status of these patients was unknown...
Increasing dietary fiber intake in terms of kiwifruit improves constipation in Chinese patientsAnnie On On Chan
Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
World J Gastroenterol 13:4771-5. 2007..To investigate if increased dietary fiber, in terms of kiwifruit, is effective in Chinese constipated patients...
Efficacy of tegaserod for functional constipation in Chinese subjects: a randomized double-blind controlled trial in a single centreA O O On Chan
Department of Medicine, The University of Hong Kong, Hong Kong
Aliment Pharmacol Ther 25:463-9. 2007..Tegaserod has been shown to be effective in chronic constipation in Western population. Aim We investigated if tegaserod is equally effective in Chinese population...
Influence of positive family history on clinical characteristics of functional constipationAnnie On On Chan
Division of Gastroenterology and Hepatology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong
Clin Gastroenterol Hepatol 5:197-200. 2007..Their clinical characteristics have not been studied. The aim of this study was to investigate the clinical characteristics of patients with functional constipation with and without a positive family history...
CpG island methylation in precursors of gastrointestinal malignanciesAnnie On On Chan
Department of Medicine, The University of Hong Kong, Hong Kong
Curr Mol Med 6:401-8. 2006..Targeting of the epigenetic changes that occur before the development of frank malignancy offers a potential chemopreventive strategy...
Coexistence between colorectal cancer/adenoma and coronary artery disease: results from 1382 patientsA O O Chan
Division of Gastroenterology and Hepatology, Department of Medicine, the University of Hongkong, Hong Kong, China
Aliment Pharmacol Ther 24:535-9. 2006..Common risk factors exist in colorectal neoplasia (cancer or adenoma) and coronary artery disease...
Prevalence of colorectal neoplasm among patients with newly diagnosed coronary artery diseaseAnnie On On Chan
Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
JAMA 298:1412-9. 2007..Colorectal neoplasm and coronary artery disease (CAD) share similar risk factors, and their co-occurrence may be associated...
Validated questionnaire on diagnosis and symptom severity for functional constipation in the Chinese populationA O O Chan
Department of Medicine, University of Hong Kong, Hong Kong
Aliment Pharmacol Ther 22:483-8. 2005..Functional constipation is a common problem in clinical practice. No validated questionnaire is available in Chinese...
E-cadherin in gastric cancerAnnie On On Chan
Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
World J Gastroenterol 12:199-203. 2006..In particular, our work on E-cadherin in gastric cancer, including its relation with Helicobacter pylori and clinical applications, are described in detail...
An inverse correlation between Interleukin-6 and select gene promoter methylation in patients with gastric cancerLi Ping Tang
Department of Medicine, University of Hong Kong, Hong Kong, SAR, China
Digestion 74:85-90. 2006..002) and signet cell histology (p = 0.001). Conclusion: IL-6 is of prognostic value for patients of gastric cancer. Low serum IL-6 levels were associated with p16 or DAPK gene methylation in patients with gastric cancer...
E-cadherin promoter hypermethylation induced by interleukin-1beta treatment or H. pylori infection in human gastric cancer cell linesXuemin Qian
Division of Gastroenterology and Hepatology, Department of Medicine, University of Hong Kong, Hong Kong
Cancer Lett 263:107-13. 2008..pylori. Treatment of IL-1ra could reverse the phenomena. Our study indicated that IL-1beta is an important step in mediating E-cadherin methylation...
Celecoxib compared with lansoprazole and naproxen to prevent gastrointestinal ulcer complicationsKam Chuen Lai
Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
Am J Med 118:1271-8. 2005..We compared the efficacy of a selective COX-2 inhibitor with that of proton pump inhibitor co-therapy in the reduction in the incidence of ulcer relapse in patients with a history of NSAID-related peptic ulcers...
Esomeprazole with aspirin versus clopidogrel for prevention of recurrent gastrointestinal ulcer complicationsKam Chuen Lai
Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China
Clin Gastroenterol Hepatol 4:860-5. 2006..We tested the hypothesis that clopidogrel is as effective as esomeprazole and aspirin in preventing recurrences of ulcer complications...
Attitudes and knowledge of colorectal cancer and screening in Hong Kong: a population-based studyBenjamin Cy Wong
Department of Medicine and Institute of Molecular Biology, University of Hong Kong, Hong Kong, China
J Gastroenterol Hepatol 21:41-6. 2006..However, participation in the CRC screening program depends on the knowledge and attitude of the population. The aim of this study is to investigate the knowledge and attitude towards CRC screening in the Hong Kong population...
Stenting of coronary bifurcation lesions by using modified crush technique with double kissing balloon inflation (sleeve technique): immediate procedure result and short-term clinical outcomesMan Hong Jim
Cardiac Medical Unit, Grantham Hospital, Hong Kong, China
Catheter Cardiovasc Interv 69:969-75. 2007..Sleeve technique is a modified version of crush technique. It is specifically designed to increase the success rate of final kissing balloon inflation, which used to be a major limitation of the latter...
Early prediction of tumor recurrence after curative resection of gastric carcinoma by measuring soluble E-cadherinAnnie On On Chan
Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong, China
Cancer 104:740-6. 2005..The use of this marker may allow time for vigilant surveillance and consideration of adjuvant therapy...
Decreasing trend of esophageal adenocarcinoma in Hong KongYuk Kei Yee
Department of Medicine, University of Hong Kong, Hong Kong
Cancer Epidemiol Biomarkers Prev 16:2637-40. 2007..The incidence of esophageal adenocarcinoma was increasing in the Western Europe and United States, but not in East Asian countries. Population based study on the trend of esophageal adenocarcinoma in Hong Kong was not available...
Prognostic implications of PR-segment depression in inferior leads in acute inferior myocardial infarctionMan Hong Jim
Department of Medicine, Queen Mary Hospital, Hong Kong, PRC
Clin Cardiol 29:363-8. 2006..PR-segment depression in the inferior leads is a simplified ECG sign for detecting possible underlying atrial ischemia...
Long-term follow-up study of Chinese patients with YMDD mutations: significance of hepatitis B virus genotypes and characteristics of biochemical flaresMan Fung Yuen
Division of Gastroenterology and Hepatology, Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Rd, Hong Kong, Peoples Republic of China
J Clin Microbiol 42:3932-6. 2004..Biochemical flares were common, with 16% being severe in nature. High pretreatment ALT levels were associated with a higher chance of biochemical flares...
Independent risk factors and predictive score for the development of hepatocellular carcinoma in chronic hepatitis BMan Fung Yuen
Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong
J Hepatol 50:80-8. 2009....
