Jun Ming Tang

Summary

Country: China

Publications

  1. Tan L, Xiao J, Yu D, Zhang L, Zheng F, Guo L, et al. PEP-1-SOD1 fusion proteins block cardiac myofibroblast activation and angiotensin II-induced collagen production. BMC Cardiovasc Disord. 2015;15:116 pubmed publisher
    ..PEP-1-SOD1 suppressed MCF proliferation and differentiation and reduced production of collagen type I and III. Therefore, PEP-1-SOD1 fusion protein may be a potential novel therapeutic agent for cardiac fibrosis. ..
  2. Chen X, Lv Y, Zhao D, Zhang L, Zheng F, Yang J, et al. Vascular endothelial growth factor-C protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis. Mol Cell Biochem. 2016;413:9-23 pubmed publisher
    ..VEGF-C exerts its cardiac protection following I/R injury via its anti-apoptotic effect. ..
  3. Li G, Luo B, Lv Y, Zheng F, Wang L, Wei M, et al. Dual effects of VEGF-B on activating cardiomyocytes and cardiac stem cells to protect the heart against short- and long-term ischemia-reperfusion injury. J Transl Med. 2016;14:116 pubmed publisher
    ..VEGF-B could contribute to a favorable short- and long-term prognosis for I/R via the dual manipulation of cardiomyocytes and CSCs. ..
  4. Tang J, Wang J, Kong X, Yang J, Guo L, Zheng F, et al. Vascular endothelial growth factor promotes cardiac stem cell migration via the PI3K/Akt pathway. Exp Cell Res. 2009;315:3521-31 pubmed publisher
    ..The CSC accumulation was inhibited by either the VEGF receptor blocker SU5416 or the PI3K/Ak inhibitor wortmannin. VEGF signaling may mediate the migration of CSCs via activation of PI3K/Akt. ..
  5. Tang J, Wang J, Zhang L, Zheng F, Yang J, Kong X, et al. VEGF/SDF-1 promotes cardiac stem cell mobilization and myocardial repair in the infarcted heart. Cardiovasc Res. 2011;91:402-11 pubmed publisher
    ..Exogenously expressed VEGF promotes myocardial repair at least in part through SDF-1?/CXCR4-mediated recruitment of CSC. ..
  6. Liu S, Wang H, Tang J, Zhou X. Hypoxia-induced collagen synthesis of human lung fibroblasts by activating the angiotensin system. Int J Mol Sci. 2013;14:24029-45 pubmed publisher
    ..Our results indicate that Ang II-mediated NF-?B signalling via ATR is involved in hypoxia-induced collagen synthesis in human lung fibroblasts...

Locale

Detail Information

Publications6

  1. Tan L, Xiao J, Yu D, Zhang L, Zheng F, Guo L, et al. PEP-1-SOD1 fusion proteins block cardiac myofibroblast activation and angiotensin II-induced collagen production. BMC Cardiovasc Disord. 2015;15:116 pubmed publisher
    ..PEP-1-SOD1 suppressed MCF proliferation and differentiation and reduced production of collagen type I and III. Therefore, PEP-1-SOD1 fusion protein may be a potential novel therapeutic agent for cardiac fibrosis. ..
  2. Chen X, Lv Y, Zhao D, Zhang L, Zheng F, Yang J, et al. Vascular endothelial growth factor-C protects heart from ischemia/reperfusion injury by inhibiting cardiomyocyte apoptosis. Mol Cell Biochem. 2016;413:9-23 pubmed publisher
    ..VEGF-C exerts its cardiac protection following I/R injury via its anti-apoptotic effect. ..
  3. Li G, Luo B, Lv Y, Zheng F, Wang L, Wei M, et al. Dual effects of VEGF-B on activating cardiomyocytes and cardiac stem cells to protect the heart against short- and long-term ischemia-reperfusion injury. J Transl Med. 2016;14:116 pubmed publisher
    ..VEGF-B could contribute to a favorable short- and long-term prognosis for I/R via the dual manipulation of cardiomyocytes and CSCs. ..
  4. Tang J, Wang J, Kong X, Yang J, Guo L, Zheng F, et al. Vascular endothelial growth factor promotes cardiac stem cell migration via the PI3K/Akt pathway. Exp Cell Res. 2009;315:3521-31 pubmed publisher
    ..The CSC accumulation was inhibited by either the VEGF receptor blocker SU5416 or the PI3K/Ak inhibitor wortmannin. VEGF signaling may mediate the migration of CSCs via activation of PI3K/Akt. ..
  5. Tang J, Wang J, Zhang L, Zheng F, Yang J, Kong X, et al. VEGF/SDF-1 promotes cardiac stem cell mobilization and myocardial repair in the infarcted heart. Cardiovasc Res. 2011;91:402-11 pubmed publisher
    ..Exogenously expressed VEGF promotes myocardial repair at least in part through SDF-1?/CXCR4-mediated recruitment of CSC. ..
  6. Liu S, Wang H, Tang J, Zhou X. Hypoxia-induced collagen synthesis of human lung fibroblasts by activating the angiotensin system. Int J Mol Sci. 2013;14:24029-45 pubmed publisher
    ..Our results indicate that Ang II-mediated NF-?B signalling via ATR is involved in hypoxia-induced collagen synthesis in human lung fibroblasts...