Jing Ping Yun

Summary

Affiliation: Sun Yat-sen University
Country: China

Publications

  1. pmc The accumulation and prognosis value of tumor infiltrating IL-17 producing cells in esophageal squamous cell carcinoma
    Lin Lv
    State Key Laboratory of Oncology in Southern China and Department of Experimental Research, Cancer Center, Sun Yat Sen University, Guangzhou, People s Republic of China
    PLoS ONE 6:e18219. 2011
  2. pmc Histone deacetylase inhibitors facilitate dihydroartemisinin-induced apoptosis in liver cancer in vitro and in vivo
    Chris Zhiyi Zhang
    State Key Laboratory of Oncology in Southern China, Sun Yat sen University Cancer Center, Guangzhou, China
    PLoS ONE 7:e39870. 2012
  3. pmc Increased expression of nucleophosmin/B23 in hepatocellular carcinoma and correlation with clinicopathological parameters
    J P Yun
    State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat Sen University, Guangzhou, China
    Br J Cancer 96:477-84. 2007
  4. pmc Primary small cell carcinoma of the esophagus: clinicopathological and immunohistochemical features of 21 cases
    Jing Ping Yun
    State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat Sen University, Guangzhou, China
    BMC Cancer 7:38. 2007
  5. doi request reprint miR-720 inhibits tumor invasion and migration in breast cancer by targeting TWIST1
    Lin Zi Li
    Sun Yat sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, People s Republic of China
    Carcinogenesis 35:469-78. 2014
  6. pmc Low BRMS1 expression promotes nasopharyngeal carcinoma metastasis in vitro and in vivo and is associated with poor patient survival
    Rui xue Cui
    Department of Radiation Oncology, Sun Yat sen University Cancer Center, Guangzhou, People s Republic of China
    BMC Cancer 12:376. 2012
  7. pmc Decreased expression of zinc-alpha2-glycoprotein in hepatocellular carcinoma associates with poor prognosis
    Yan Huang
    Department of Pathology, State Key Laboratory of Oncology in South China, Sun Yat sen University Cancer Center, Guangzhou, China
    J Transl Med 10:106. 2012
  8. doi request reprint Identification of a 7-gene signature that predicts relapse and survival for early stage patients with cervical carcinoma
    Long Huang
    State Key Laboratory of Oncology in Southern China and Department of Gynecology, Cancer Center, Sun Yat Sen University, and Department of Obstetrics and Gynecology, Nanfang Hospital, 651 Dongfeng Road East, Guangzhou, 510060, People s Republic of China
    Med Oncol 29:2911-8. 2012
  9. doi request reprint High-expression of ZBP-89 correlates with distal metastasis and poor prognosis of patients in clear cell renal cell carcinoma
    Mu Yan Cai
    State Key Laboratory of Oncology in Southern China, Sun Yat sen University Cancer Center, Guangzhou 510060, China
    Biochem Biophys Res Commun 426:636-42. 2012
  10. pmc The prognostic effect of perineural invasion in esophageal squamous cell carcinoma
    Jie Wei Chen
    Sun Yat sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine, Guangzhou, China
    BMC Cancer 14:313. 2014

Collaborators

Detail Information

Publications34

  1. pmc The accumulation and prognosis value of tumor infiltrating IL-17 producing cells in esophageal squamous cell carcinoma
    Lin Lv
    State Key Laboratory of Oncology in Southern China and Department of Experimental Research, Cancer Center, Sun Yat Sen University, Guangzhou, People s Republic of China
    PLoS ONE 6:e18219. 2011
    ..The role of IL-17 producing cells in tumors is controversial. In the present study, we investigated the prognostic value of measuring tumor-infiltrating IL-17 producing cell levels in human esophageal squamous cell carcinoma (ESCC)...
  2. pmc Histone deacetylase inhibitors facilitate dihydroartemisinin-induced apoptosis in liver cancer in vitro and in vivo
    Chris Zhiyi Zhang
    State Key Laboratory of Oncology in Southern China, Sun Yat sen University Cancer Center, Guangzhou, China
    PLoS ONE 7:e39870. 2012
    ..Taken together, our data suggest that the combination of HDACi and DHA offers an antitumor effect on liver cancer, and this combination treatment should be considered as a promising strategy for chemotherapy...
  3. pmc Increased expression of nucleophosmin/B23 in hepatocellular carcinoma and correlation with clinicopathological parameters
    J P Yun
    State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat Sen University, Guangzhou, China
    Br J Cancer 96:477-84. 2007
    ..05). Our results suggest that NPM may play an important role in the progression of tumorigenesis and that NPM may serve as a potential marker for HCC...
  4. pmc Primary small cell carcinoma of the esophagus: clinicopathological and immunohistochemical features of 21 cases
    Jing Ping Yun
    State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat Sen University, Guangzhou, China
    BMC Cancer 7:38. 2007
    ....
  5. doi request reprint miR-720 inhibits tumor invasion and migration in breast cancer by targeting TWIST1
    Lin Zi Li
    Sun Yat sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, People s Republic of China
    Carcinogenesis 35:469-78. 2014
    ..Collectively, our data indicate that miR-720 is frequently decreased in breast cancer and manifests antimetastatic activity by downregulating TWIST1, presenting a novel mechanism of miRNA-mediated regulation of tumor metastasis. ..
  6. pmc Low BRMS1 expression promotes nasopharyngeal carcinoma metastasis in vitro and in vivo and is associated with poor patient survival
    Rui xue Cui
    Department of Radiation Oncology, Sun Yat sen University Cancer Center, Guangzhou, People s Republic of China
    BMC Cancer 12:376. 2012
    ..This study aimed to investigate the impact of BRMS1 on metastasis in nasopharyngeal carcinoma (NPC) and to evaluate the prognostic significance of BRMS1 in NPC patients...
  7. pmc Decreased expression of zinc-alpha2-glycoprotein in hepatocellular carcinoma associates with poor prognosis
    Yan Huang
    Department of Pathology, State Key Laboratory of Oncology in South China, Sun Yat sen University Cancer Center, Guangzhou, China
    J Transl Med 10:106. 2012
    ..Zinc-alpha2-glycoprotein (AZGP1, ZAG) was recently demonstrated to be an important factor in tumor carcinogenesis. However, AZGP1 expression in hepatocellular carcinoma (HCC) and its significance remain largely unknown...
  8. doi request reprint Identification of a 7-gene signature that predicts relapse and survival for early stage patients with cervical carcinoma
    Long Huang
    State Key Laboratory of Oncology in Southern China and Department of Gynecology, Cancer Center, Sun Yat Sen University, and Department of Obstetrics and Gynecology, Nanfang Hospital, 651 Dongfeng Road East, Guangzhou, 510060, People s Republic of China
    Med Oncol 29:2911-8. 2012
    ..The 7-gene signature can predict cancer recurrence and survival of cervical cancer patients. This may have prognostic or therapeutic implications for the future management of cervical cancer patients...
  9. doi request reprint High-expression of ZBP-89 correlates with distal metastasis and poor prognosis of patients in clear cell renal cell carcinoma
    Mu Yan Cai
    State Key Laboratory of Oncology in Southern China, Sun Yat sen University Cancer Center, Guangzhou 510060, China
    Biochem Biophys Res Commun 426:636-42. 2012
    ..853; P=0.004). Collectively, our study provides vigorous evidence that ZBP-89 was significantly downregulated in CCRCC and could be served as a promising biomarker for prediction of distal metastasis and prognosis of patient with CCRCC...
  10. pmc The prognostic effect of perineural invasion in esophageal squamous cell carcinoma
    Jie Wei Chen
    Sun Yat sen University Cancer Center State Key Laboratory of Oncology in South China Collaborative Innovation Center for Cancer Medicine, Guangzhou, China
    BMC Cancer 14:313. 2014
    ..The objective of this study was to determine the association between PNI status and clinical outcomes...
  11. pmc Decreased expression of PTPN12 correlates with tumor recurrence and poor survival of patients with hepatocellular carcinoma
    Rong zhen Luo
    Sun Yat sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China Department of Pathology, Sun Yat sen University Cancer Center, Guangzhou, China
    PLoS ONE 9:e85592. 2014
    ..However, the PTPN12 expression and its prognostic significance in HCC have not been well elucidated...
  12. pmc Knockdown of miR-21 in human breast cancer cell lines inhibits proliferation, in vitro migration and in vivo tumor growth
    Li Xu Yan
    State Key Laboratory of Oncology in Southern China, Sun Yat sen University Cancer Center, 651 Dong Feng Road East, Guangzhou, 510060, PR China
    Breast Cancer Res 13:R2. 2011
    ..However, few functional studies are available for miR-21, and few targets have been identified. In this study, we explored the role of miR-21 in human breast cancer cells and tissues, and searched for miR-21 targets...
  13. ncbi request reprint NORE1A sensitises cancer cells to sorafenib-induced apoptosis and indicates hepatocellular carcinoma prognosis
    Li li Liu
    State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat sen University Cancer Center, No 651, Dongfeng Road East, Guangzhou, 510060, China
    Tumour Biol 35:1763-74. 2014
    ..Collectively, our data suggest that NORE1A may be a promising prognostic biomarker and therapeutic target in HCC...
  14. pmc Knockdown of nucleophosmin induces S-phase arrest in HepG2 cells
    Qing qing Wang
    Department of Pathology, Sun Yat sen University Cancer Center, Guangzhou, Guangdong, People s Republic of China
    Chin J Cancer 30:853-60. 2011
    ..Furthermore, knockdown of NPM abrogated ActD-induced G2/M phase cell cycle arrest. Taken together, these data demonstrate that inhibition of NPM has a significant effect on the cell cycle...
  15. ncbi request reprint [Expression of CD56, as a potential diagnostic marker, in small cell carcinoma]
    Jing Ping Yun
    State Key Laboratory of Oncology in Southern China, Guangzhou, Guangdong, P R China
    Ai Zheng 24:1140-3. 2005
    ..This study was to investigate the expression of CD56, a neural cell adhesion molecule (NCAM), in small cell carcinoma tissues, and to explore the possibility of CD56 as a diagnostic marker of small cell carcinoma...
  16. doi request reprint An in situ molecular signature to predict early recurrence in hepatitis B virus-related hepatocellular carcinoma
    Jing Xu
    State Key Laboratory of Oncology in South China, Cancer Center, Sun Yat Sen Zhongshan University, Guangzhou, PR China
    J Hepatol 57:313-21. 2012
    ..To develop an in situ molecular signature to predict postsurgical recurrence in hepatocellular carcinoma (HCC) patients...
  17. pmc Correlation between expression of p53, p21/WAF1, and MDM2 proteins and their prognostic significance in primary hepatocellular carcinoma
    Mei Fang Zhang
    State Key Laboratory of Oncology in Southern China, Cancer Center of Sun Yat Sen University, Guangzhou, China
    J Transl Med 7:110. 2009
    ..Our aim was to investigate the expression of the 3 proteins in hepatocellular carcinoma (HCC) and their prognostic significance...
  18. pmc Prognostic significance of the pN classification supplemented by vascular invasion for esophageal squamous cell carcinoma
    Chong Mei Zhu
    Sun Yat sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, China Department of Pathology, Sun Yat sen University Cancer Center, Guangzhou, China
    PLoS ONE 9:e96129. 2014
    ..The biological behavior and clinical outcome of esophageal squamous cell carcinoma (ESCC) are difficult to predict...
  19. doi request reprint Clinicopathologic significance of putative stem cell marker, CD44 and CD133, in human gastric carcinoma
    Shi Chen
    The State Key Laboratory of Oncology in South China, Sun Yat sen University Cancer Center, Guangzhou, China
    J Surg Oncol 107:799-806. 2013
    ..CD44 and CD133 have been reported as putative stem cell markers. However, the clinicopathologic significance of CD44 and CD133 expression in patients with gastric carcinoma (GC) has not been clearly elucidated...
  20. pmc Overexpression of karyopherin 2 in human ovarian malignant germ cell tumor correlates with poor prognosis
    Li He
    State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat Sen University, Guangzhou, Guangdong, People s Republic of China
    PLoS ONE 7:e42992. 2012
    ..The aim of this study was to identify a biomarker useful in the diagnosis and therapy of ovarian malignant germ cell tumor (OMGCT)...
  21. pmc Overexpression of ZEB2 in peritumoral liver tissue correlates with favorable survival after curative resection of hepatocellular carcinoma
    Mu Yan Cai
    State Key Laboratory of Oncology in South China, Guangzhou, China
    PLoS ONE 7:e32838. 2012
    ..However, the expression patterns of ZEB2 in hepatocellular carcinoma (HCC) and its effect on prognosis of HCC patients treated with hepatectomy are unclear...
  22. pmc Upregulator of cell proliferation predicts poor prognosis in hepatocellular carcinoma and contributes to hepatocarcinogenesis by downregulating FOXO3a
    Chan Xie
    Department of Infectious Diseases, The Third Affiliated Hospital of Sun Yat Sen University, Guangzhou, Guangdong Province, China
    PLoS ONE 7:e40607. 2012
    ....
  23. ncbi request reprint Nucleophosmin/B23 interacts with p21WAF1/CIP1 and contributes to its stability
    Jianyong Xiao
    Department of Pathology, Cancer Center of Sun Yat Sen University, Guangzhou, China
    Cell Cycle 8:889-95. 2009
    ..Altogether, we provide evidence for a direct binding between NPM and p21, and assign NPM as a positive post-translational regulator of p21...
  24. ncbi request reprint Prognostic value of a microRNA signature in nasopharyngeal carcinoma: a microRNA expression analysis
    Na Liu
    Department of Radiation Oncology, Sun Yat sen University Cancer Center, Guangzhou, China
    Lancet Oncol 13:633-41. 2012
    ..MicroRNAs (miRNAs) can be used as prognostic biomarkers in many types of cancer. We aimed to identify miRNAs that were prognostic in patients with nasopharyngeal carcinoma...
  25. doi request reprint A clinicopathological aspect of primary small-cell carcinoma of the uterine cervix: a single-centre study of 25 cases
    Jun Dong Li
    State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat Sen University, Guangzhou, PR China
    J Clin Pathol 64:1102-7. 2011
    ..In this study, the authors report 25 Chinese cases of SCCC, with a particular focus on their clinical and pathological characteristics...
  26. ncbi request reprint Effects of microRNA-29 on apoptosis, tumorigenicity, and prognosis of hepatocellular carcinoma
    Yujuan Xiong
    Key Laboratory of Gene Engineering of the Ministry of Education, State Key Laboratory of Biocontrol, School of Life Sciences, Sun Yat Sen University, China
    Hepatology 51:836-45. 2010
    ....
  27. doi request reprint Identification of a gene-expression signature for predicting lymph node metastasis in patients with early stage cervical carcinoma
    Long Huang
    State Key Laboratory of Oncology in Southern China, Cancer Center, Sun Yat Sen University, Guangzhou, People s Republic of China
    Cancer 117:3363-73. 2011
    ..Pelvic lymph node metastasis (PLNM) is an important prognostic factor for patients with cervical carcinoma. The objective of this study was to identify a gene-expression signature that could predict PLNM in cervical carcinoma...
  28. ncbi request reprint Tumor-educated tolerogenic dendritic cells induce CD3epsilon down-regulation and apoptosis of T cells through oxygen-dependent pathways
    Dong Ming Kuang
    State Key Laboratory of Biocontrol, Sun Yat Sen University, Guangzhou, People s Republic of China
    J Immunol 181:3089-98. 2008
    ....
  29. pmc High expression of GOLPH3 in esophageal squamous cell carcinoma correlates with poor prognosis
    Jian Hua Wang
    Department of Chest, Second People s Hospital of Guangdong Province, Guangzhou, Guangdong, PR China
    PLoS ONE 7:e45622. 2012
    ..The aim of this study was to examine GOLPH3 expression in patients with esophageal squamous cell cancer (ESCC) and explore its clinical significance...
  30. ncbi request reprint Nuclear matrix protein expressions in hepatocytes of normal and cirrhotic rat livers under normal and regenerating conditions
    Jing Ping Yun
    Department of Pathology, Cancer Center of Sun Yat Sen University, Guangzhou, China
    J Cell Biochem 91:1269-79. 2004
    ..Some of the NMPs are specific for liver regeneration and may play a critical role in cell proliferation and cell cycle, and some are specific for liver cirrhosis...
  31. ncbi request reprint Identification and characterization of BH3 domain protein Bim and its isoforms in human hepatocellular carcinomas
    Ji Miao
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Apoptosis 12:1691-701. 2007
    ..In conclusion, Bim alpha isoforms appears to have a role in the regulation of apoptosis in HCC cells, which may contribute to not only the growth of tumor cells but also the sensitivity of HCC cells to chemotherapy...
  32. ncbi request reprint Adenovirus-mediated tBid overexpression results in therapeutic effects on p53-resistant hepatocellular carcinoma
    Ji Miao
    Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, New Territories, Hong Kong
    Int J Cancer 119:1985-93. 2006
    ..The cell death induced by Ad/AFPtBid in HCC cells is via an apoptotic pathway that can be independent of p53 status...
  33. ncbi request reprint Nucleophosmin/B23 is a proliferate shuttle protein associated with nuclear matrix
    Jing Ping Yun
    Department of Pathology, Cancer Center of Sun Yat Sen University, Guangzhou 510060, China
    J Cell Biochem 90:1140-8. 2003
    ..1 and molecular weight of 40 kDa. These results indicated that B23 was a proliferate shuttle protein involving in cell cycle and cell proliferation associated with nuclear matrix...